Population Pharmacokinetic Meta-Analysis of Denosumab in Healthy Subjects and Postmenopausal Women with Osteopenia or Osteoporosis - Sutjandra, Liviawati; Rodriguez, Rachelle D.; Doshi, Sameer; Ma, Mark; Peterson, Mark C.; Jang, Graham R.; Chow, Andrew T.; Pérez-Ruixo, Juan José (Clinical pharmacokinetics, 2011)
Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal - blood; Antibodies, Monoclonal - pharmacokinetics; Antibodies, Monoclonal, Humanized; Biological and medical sciences; Bone Density Conservation Agents - blood; Bone Density Conservation Agents - pharmacokinetics; Bone Diseases, Metabolic - blood; Bone Diseases, Metabolic - drug therapy; Denosumab; Diagnosis; Diseases of the osteoarticular system; Drug therapy; Female; General pharmacology; Health aspects; Humans; Internal Medicine; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Models, Biological; Original Research Article; Osteopenia; Osteoporosis; Osteoporosis - blood; Osteoporosis - drug therapy; Osteoporosis. Osteomalacia. Paget disease; Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions; Pharmacology. Drug treatments; Pharmacology/Toxicology; Pharmacotherapy; Postmenopausal women; Postmenopause - blood; RANK Ligand - antagonists & inhibitors; Young Adult; Spain; Omalizumab; Ustekinumab; Denosumab; Stochastic Approximation Expectation Maximization; Conditional Weighted Residual; Human; Population pharmacokinetics; Healthy subject; Menopause; Diseases of the osteoarticular system; Monoclonal antibody; Metaanalysis; Immunomodulator; Osteoporosis; Postmenopause; Adult; Female; Woman; Osteopenia