Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice - Crozier, Stephen J.; Sans, M. Dolors; Guo, LiLi; D'Alecy, Louis G.; Williams, John A. (The Journal of physiology, 2006)
Keywords: Alimentary; Animals; Carrier Proteins - metabolism; Diet; DNA - biosynthesis; Gabexate - administration & dosage; Gabexate - analogs & derivatives; Gabexate - pharmacology; Male; Mice; Mice, Inbred ICR; Organ Size; Pancreas - drug effects; Pancreas - enzymology; Pancreas - growth & development; Phosphoproteins - metabolism; Phosphorylation; Protease Inhibitors - administration & dosage; Protease Inhibitors - pharmacology; Protein Biosynthesis; Protein Kinase Inhibitors - administration & dosage; Protein Kinase Inhibitors - pharmacology; Protein Kinases - metabolism; Ribosomal Protein S6 - metabolism; Signal Transduction; Sirolimus - administration & dosage; Sirolimus - pharmacology; TOR Serine-Threonine Kinases