Rationale and design of the COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 trial): A randomized, placebo-controlled, multicenter study on the use of colchicine for the primary prevention of the postpericardiotomy syndrome, postoperative effusions, and postoperative atrial fibrillation - Imazio, Massimo; Belli, Riccardo; Brucato, Antonio; Ferrazzi, Paolo; Patrini, Davide; Martinelli, Luigi; Polizzi, Vincenzo; Cemin, Roberto; Leggieri, Anna; Caforio, Alida L.P.; Finkelstein, Yaron; Hoit, Brian; et al. (The American heart journal, 2013)
Keywords: Aspirin; Atrial Fibrillation - etiology; Atrial Fibrillation - prevention & control; Cardiac arrhythmia; Cardiovascular; Cell adhesion & migration; Clinical trials; Colchicine - therapeutic use; Drug therapy; Fever; Heart surgery; Humans; Multicenter Studies as Topic - methods; Nonsteroidal anti-inflammatory drugs; Older people; Patients; Pericardial Effusion - etiology; Pericardial Effusion - prevention & control; Pericardiectomy - adverse effects; Postoperative Complications - etiology; Postoperative Complications - prevention & control; Primary Prevention - methods; Randomized Controlled Trials as Topic - methods; Syndrome; Tubulin Modulators - therapeutic use