Chondromyxoid fibroma of the lumbar spine: case report and literature review
Purpose Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one in...
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Published in | European spine journal Vol. 21; no. Suppl 4; pp. 458 - 462 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Springer-Verlag
01.06.2012
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
ISSN | 0940-6719 1432-0932 1432-0932 |
DOI | 10.1007/s00586-011-2078-x |
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Abstract | Purpose
Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone.
Methods
A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5.
Results
Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up.
Conclusion
Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour. |
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AbstractList | Purpose: Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone. Methods: A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5. Results: Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up. Conclusion: Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour. Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone. A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5. Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up. Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour. Purpose Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone. Methods A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5. Results Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up. Conclusion Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour. Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone.PURPOSEChondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone.A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5.METHODSA 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5.Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up.RESULTSComplete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up.Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour.CONCLUSIONDespite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour. Issue Title: Supplement for Case Reports online only 2012 Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in the cervical and thoracic segments. Lumbar involvement is extremely rare. We report the ninth case of lumbar CMF and the first one involving the articular process of the vertebra. A review of the literature is also intended making special emphasis on the differential diagnosis with other benign spinal tumours of the bone. A 21-year-old Caucasian male suffering from low back pain that increased with sports and interrupted sleep was diagnosed with a tumoural lesion in the right inferior articular process of L5. Complete surgical excision of the tumour was accomplished. Histological diagnosis confirmed a CMF. The patient remains asymptomatic at 1-year follow-up. Despite the low incidence of CMF in the lumbar spine, differential diagnosis must include this subtype of lesion among other benign tumours of the bone and cartilage. Histological diagnosis is essential in order to provide the patient with an accurate management of the pathology. Recurrence rate is to be considered even in the case of complete surgical excision. Radiotherapy administration is controversial due to suspicion of malignant transformation of the tumour.[PUBLICATION ABSTRACT] |
Author | Gutiérrez-González, Raquel Saab, Anwar García-Uría, José Jiménez-Heffernan, José De Reina, Laura |
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Cites_doi | 10.3928/01477447-20080601-27 10.1016/S0046-8177(98)90058-2 10.1016/j.ejrad.2005.12.006 10.1007/s002560050271 10.1002/1097-0142(197209)30:3<726::AID-CNCR2820300321>3.0.CO;2-T 10.1007/s00586-006-0188-7 10.1302/0301-620X.53B2.198 10.2106/00004623-198365020-00008 |
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Keywords | Chondromyxoid fibroma Treatment Lumbar Spine |
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References_xml | – volume: 53 start-page: 198 year: 1971 end-page: 216 ident: CR11 article-title: Chondromyxoid fibroma of bone. A clinico-pathological study of thirty-two cases publication-title: J Bone Joint Surg Br – start-page: 117 year: 2007 end-page: 130 ident: CR9 article-title: Benign bony tumours of the spine publication-title: Tumors of the spine and spinal cord – volume: 29 start-page: 50 year: 1968 end-page: 52 ident: CR1 article-title: A case of chondromyxoid fibroma of the spine publication-title: Ortop Traum Protez – volume: 31 start-page: 610 year: 2008 ident: CR6 article-title: Chondromyxoid fibroma of the lumbar spine in a pediatric patient publication-title: Orthopedics doi: 10.3928/01477447-20080601-27 – volume: 49 start-page: 305 year: 1975 end-page: 312 ident: CR2 article-title: Chondromyxoid fibroma of the vertebra. Report of a case publication-title: J Jpn Orthop Assoc – volume: 29 start-page: 438 year: 1998 end-page: 446 ident: CR5 article-title: Chondromyxoid fibroma of bone: a clinicopathologic review of 278 cases publication-title: Hum Pathol doi: 10.1016/S0046-8177(98)90058-2 – volume: 58 start-page: 48 year: 2006 end-page: 67 ident: CR8 article-title: Imaging and differential diagnosis of primary bone tumors and tumor-like lesions of the spine publication-title: Eur J Radiol doi: 10.1016/j.ejrad.2005.12.006 – volume: 26 start-page: 488 year: 1997 end-page: 492 ident: CR4 article-title: Chondromyxoid fibroma of the lumbar spine publication-title: Skeletal Radiol doi: 10.1007/s002560050271 – volume: 45 start-page: 541 year: 1948 end-page: 551 ident: CR10 article-title: Chondromyxoid fibroma of bone: a distinctive benign tumor likely to be mistaken especially for chondrosarcoma publication-title: Arch Pathol – volume: 30 start-page: 726 year: 1972 end-page: 736 ident: CR13 article-title: Chondromyxoid fibroma: a clinicopathologic study of 76 cases publication-title: Cancer doi: 10.1002/1097-0142(197209)30:3<726::AID-CNCR2820300321>3.0.CO;2-T – volume: 16 start-page: 405 year: 2007 end-page: 409 ident: CR7 article-title: Primary bone tumours of the spine: a 42-year survey from the Leeds Regional Bone Tumour Registry publication-title: Eur Spine J doi: 10.1007/s00586-006-0188-7 – volume: 29 start-page: 271 year: 1978 end-page: 272 ident: CR3 article-title: Chondromyxoid fibroma of lumbar spine publication-title: J Can Assoc Radiol – volume: 65 start-page: 198 year: 1983 end-page: 204 ident: CR12 article-title: Chondromyxoid fibroma. The experience at the Instituto Ortopedico Rizzoli publication-title: J Bone Joint Surg Am – volume: 53 start-page: 198 year: 1971 ident: 2078_CR11 publication-title: J Bone Joint Surg Br doi: 10.1302/0301-620X.53B2.198 – volume: 58 start-page: 48 year: 2006 ident: 2078_CR8 publication-title: Eur J Radiol doi: 10.1016/j.ejrad.2005.12.006 – volume: 26 start-page: 488 year: 1997 ident: 2078_CR4 publication-title: Skeletal Radiol doi: 10.1007/s002560050271 – volume: 16 start-page: 405 year: 2007 ident: 2078_CR7 publication-title: Eur Spine J doi: 10.1007/s00586-006-0188-7 – start-page: 117 volume-title: Tumors of the spine and spinal cord year: 2007 ident: 2078_CR9 – volume: 29 start-page: 438 year: 1998 ident: 2078_CR5 publication-title: Hum Pathol doi: 10.1016/S0046-8177(98)90058-2 – volume: 31 start-page: 610 year: 2008 ident: 2078_CR6 publication-title: Orthopedics doi: 10.3928/01477447-20080601-27 – volume: 30 start-page: 726 year: 1972 ident: 2078_CR13 publication-title: Cancer doi: 10.1002/1097-0142(197209)30:3<726::AID-CNCR2820300321>3.0.CO;2-T – volume: 29 start-page: 271 year: 1978 ident: 2078_CR3 publication-title: J Can Assoc Radiol – volume: 65 start-page: 198 year: 1983 ident: 2078_CR12 publication-title: J Bone Joint Surg Am doi: 10.2106/00004623-198365020-00008 – volume: 45 start-page: 541 year: 1948 ident: 2078_CR10 publication-title: Arch Pathol – volume: 29 start-page: 50 year: 1968 ident: 2078_CR1 publication-title: Ortop Traum Protez – volume: 49 start-page: 305 year: 1975 ident: 2078_CR2 publication-title: J Jpn Orthop Assoc |
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Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more... Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more frequent in... Issue Title: Supplement for Case Reports online only 2012 Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone... Purpose: Chondromyxoid fibroma (CMF) is a benign tumour of the bone that typically occurs in long bone metaphysis. Spinal involvement is uncommon, but more... |
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SubjectTerms | Benign Bone (long) Cartilage Case Report Case reports Differential diagnosis Fibroma - diagnostic imaging Fibroma - pathology Fibroma - surgery Humans Literature reviews Low back pain Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - pathology Lumbar Vertebrae - surgery Male Medicine Medicine & Public Health Metaphysis Neurosurgery Radiography Radiotherapy Sleep Spinal Neoplasms - diagnostic imaging Spinal Neoplasms - pathology Spinal Neoplasms - surgery Spine Spine (lumbar) Sports Surgical Orthopedics Thorax Transformation Treatment Outcome Vertebrae Young Adult |
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Title | Chondromyxoid fibroma of the lumbar spine: case report and literature review |
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