3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs - Nunes, Ana S.; Barros, Andreia S.; Costa, Elisabete C.; Moreira, André F.; Correia, Ilídio J. (Biotechnology and bioengineering, 2019)
Keywords: Anticancer properties; Antineoplastic Agents - pharmacology; Antitumor agents; Cancer; Cell culture; Cell Line, Tumor; Cellular structure; Drug resistance; Drug Resistance, Neoplasm; Drug screening; drugs; Humans; Hypoxia; in vitro models; Models, Theoretical; Solid tumors; Spheroids; Spheroids, Cellular - drug effects; Structure-function relationships; Three dimensional models; Tumors; drug resistance; spheroids; drugs; in vitro models; solid tumors