Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity - Cruz, Esteban; Sifniotis, Vicki; Sumer-Bayraktar, Zeynep; Reslan, Mouhamad; Wilkinson-White, Lorna; Cordwell, Stuart; Kayser, Veysel (Pharmaceutics, 2021)
Keywords: Amino acids; biobetters; Cloning; Enzymes; Glycosylation; Manufacturing; Monoclonal antibodies; Mutagenesis; Mutation; Pharmaceutical industry; protein aggregation; Proteins; Regulatory approval; therapeutic monoclonal antibodies; Trastuzumab; Sydney New South Wales Australia; Melbourne Victoria Australia; Australia; United States--US