Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma - Shanmugam, Vignesh; Griffin, Gabriel K.; Jacobsen, Eric D.; Fletcher, Christopher D. M.; Sholl, Lynette M.; Hornick, Jason L. (Modern pathology, 2019)
Keywords: 1-Phosphatidylinositol 3-kinase; 692/420/755; 692/699/67/69; 82/51; Adolescent; Adult; Aged; Aged, 80 and over; B-cell lymphoma; Child; Cyclin-dependent kinase 4; Cyclin-dependent kinase inhibitors; Female; Histiocytic Sarcoma - genetics; Histiocytic Sarcoma - pathology; Histiocytosis; Humans; INK4 protein; Laboratory Medicine; Langerhans cell histiocytosis; Lymphocytes B; Macrophages; Male; MAP kinase; MAP Kinase Signaling System - genetics; Medicine; Medicine & Public Health; MEK inhibitors; Middle Aged; Mutation; Next-generation sequencing; Pathology; PTEN protein; ras Proteins - genetics; Sarcoma; Signal transduction; TOR protein; Tumors; Young Adult