Functional Characterization of Human Pluripotent Stem Cell-Derived Models of the Brain with Microelectrode Arrays - Pelkonen, Anssi; Pistono, Cristiana; Klecki, Pamela; Gómez-Budia, Mireia; Dougalis, Antonios; Konttinen, Henna; Stanová, Iveta; Fagerlund, Ilkka; Leinonen, Ville; Korhonen, Paula; Malm, Tarja (Cells (Basel, Switzerland), 2021)
Keywords: Alzheimer's disease; Arrays; Brain - physiology; Brain research; Cell culture; Design; differentiation; disease modeling; Electric potential; Electrodes; functional characterization; Gene expression; Humans; microelectrode array; Microelectrodes; Microenvironments; Models, Biological; neuronal network; Neurons; Neurons - physiology; Neurosciences; Organoids; Organoids - physiology; Pluripotency; pluripotent stem cells; Pluripotent Stem Cells - metabolism; Review; Signal transduction; Silicon; Stem cells; Transcription factors; United States--US; Utah; Michigan; microelectrode array; cell phenotype; differentiation; pluripotent stem cells; neuronal network; disease modeling; brain; neurons; functional characterization