Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians - Piaggi, Paolo; Köroğlu, Çiğdem; Nair, Anup K; Sutherland, Jeff; Muller, Yunhua L; Kumar, Pankaj; Hsueh, Wen-Chi; Kobes, Sayuko; Shuldiner, Alan R; Kim, Hye In; Gosalia, Nehal; Van Hout, Cristopher V; et al. (The journal of clinical endocrinology and metabolism, 2020)
Keywords: Adolescent; Adult; Alleles; American Indians or Alaska Natives - genetics; Amino acid oxidase; Analysis; Clinical s; Codon; Codon, Nonsense; D-Amino-acid oxidase; D-Amino-Acid Oxidase - genetics; Dopamine; Energy balance; Energy expenditure; Energy metabolism; Energy Metabolism - genetics; Ethylenediaminetetraacetic acid; Exome; Female; Gene Frequency; Genetic analysis; Genetic diversity; Glucose Tolerance Test; Humans; Male; Middle Aged; Minority & ethnic groups; Native Americans; Native North Americans; Nonsense mutation; Obesity; Obesity - genetics; Oxidases; Proteolysis; Stop codon; Type 2 diabetes; Whole Exome Sequencing; Young Adult; India; respiratory quotient; energy expenditure; thrifty metabolic phenotype; whole-exome sequencing; energy metabolism