The Impact of Genetic Polymorphisms in Glutamate-Cysteine Ligase, a Key Enzyme of Glutathione Biosynthesis, on Ischemic Stroke Risk and Brain Infarct Size - Polonikov, Alexey; Bocharova, Iuliia; Azarova, Iuliia; Klyosova, Elena; Bykanova, Marina; Bushueva, Olga; Polonikova, Anna; Churnosov, Mikhail; Solodilova, Maria (Life (Basel, Switzerland), 2022)
Keywords: Alcohol; Biosynthesis; Brain damage; brain infarction; Brain injury; Brain research; Carotid arteries; Cell cycle; Cerebrovascular disease; Cysteine; Environmental factors; Environmental risk; Enzymes; Epigenetics; Epistasis; Fruits; GCLC; GCLM; Gene polymorphism; Genes; Glutamate-cysteine ligase; Glutathione; Haplotypes; Health care; Health risks; Homeostasis; Ischemia; ischemic stroke; Metabolism; Nucleotides; Outdoor air quality; Oxidative stress; Patients; Physiology; Plasma; Regression analysis; Risk analysis; Risk factors; Sex; Signal transduction; Single-nucleotide polymorphism; Smoking; Stroke; Vegetables; United States--US; gene–gene interactions; GCLC; brain infarction; single nucleotide polymorphism; glutathione; gene–environment interactions; GCLM; ischemic stroke; oxidative stress