HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer - Lin, Ching-Ling; Tsai, Ming-Lin; Lin, Chun-Yu; Hsu, Kai-Wen; Hsieh, Wen-Shyang; Chi, Wei-Ming; Huang, Li-Chi; Lee, Chia-Hwa (International journal of molecular sciences, 2019)
Keywords: Acetylation; Apoptosis; Apoptosis - drug effects; Apoptosis - genetics; Cell Line, Tumor; CRISPR-Cas Systems; FDA approval; Gene Editing; Gene Expression Regulation, Neoplastic - drug effects; Gene Knockout Techniques; Histone Deacetylase 1 - genetics; Histone Deacetylase 2 - genetics; Histone Deacetylase Inhibitors - pharmacology; Histones - metabolism; Humans; Investigations; Mutation; Neoplasm Metastasis; Neoplasm Staging; Thyroid cancer; Thyroid Neoplasms - drug therapy; Thyroid Neoplasms - genetics; Thyroid Neoplasms - metabolism; Thyroid Neoplasms - pathology; United States--US; anaplastic thyroid carcinoma; knockout; CRISPR/Cas9; squamous thyroid carcinoma; histone deacetylase inhibitor