Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis - Puchalska, Patrycja; Martin, Shannon E.; Huang, Xiaojing; Lengfeld, Justin E.; Daniel, Bence; Graham, Mark J.; Han, Xianlin; Nagy, Laszlo; Patti, Gary J.; Crawford, Peter A. (Cell metabolism, 2019)
Keywords: 3-Hydroxybutyric Acid - metabolism; acetoacetate; Acetoacetates - metabolism; Animals; beta-hydroxybutyrate; fibrosis; Hepatocytes - metabolism; Hepatocytes - pathology; immunometabolism; ketone bodies; Liver Cirrhosis, Experimental - metabolism; macrophages; Macrophages - cytology; Macrophages - metabolism; Mice; Mice, Inbred C57BL; Mitochondria - metabolism; nonalcoholic fatty liver disease; stable isotope tracing untargeted metabolomics; macrophages; stable isotope tracing untargeted metabolomics; nonalcoholic fatty liver disease; acetoacetate; immunometabolism; beta-hydroxybutyrate; ketone bodies; fibrosis