The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study - Pirtle, Jimmie L.; Hickman, Melissa D.; Boinpelly, Varun C.; Surineni, Kamalakar; Thakur, Hemant K.; Grasing, Kenneth W. (Pharmacology, biochemistry and behavior, 2019)
Keywords: Administration, Intravenous; Administration, Oral; Adult; Benzazepines - administration & dosage; Benzazepines - adverse effects; Benzazepines - pharmacology; Blood Pressure - drug effects; Cocaine - administration & dosage; Cocaine - adverse effects; Cocaine - pharmacology; Cocaine-related disorders; Cocaine-Related Disorders - drug therapy; Craving - drug effects; Cross-Over Studies; Depression, Chemical; Dose-response relationship; Double-Blind Method; Drug interactions; Drug Therapy, Combination; Heart Rate - drug effects; Humans; Infusions; Intravenous; Male; Middle Aged; Self Administration; Serotonin 5-HT2 Receptor Agonists - administration & dosage; Serotonin 5-HT2 Receptor Agonists - adverse effects; Serotonin 5-HT2 Receptor Agonists - pharmacology; Serotonin receptor agonists; Stimulation, Chemical; Treatment Outcome; Vasoconstrictor Agents - administration & dosage; Vasoconstrictor Agents - adverse effects; Vasoconstrictor Agents - pharmacology; Cocaine-related disorders; Self-administration; Intravenous; Serotonin receptor agonists; Drug interactions; Dose-response relationship; Infusions