Defining the Patient with Lumbar Discogenic Pain: Real-World Implications for Diagnosis and Effective Clinical Management
There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative disc disease, the specific diagnostic criteria lack clarity and fail to capture the primary components which include axial midline low back pain...
        Saved in:
      
    
          | Published in | Journal of personalized medicine Vol. 13; no. 5; p. 821 | 
|---|---|
| Main Authors | , , , , , | 
| Format | Journal Article | 
| Language | English | 
| Published | 
        Switzerland
          MDPI AG
    
        12.05.2023
     MDPI  | 
| Subjects | |
| Online Access | Get full text | 
| ISSN | 2075-4426 2075-4426  | 
| DOI | 10.3390/jpm13050821 | 
Cover
| Abstract | There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative disc disease, the specific diagnostic criteria lack clarity and fail to capture the primary components which include axial midline low back pain with or without non-radicular/non-sciatic referred leg pain in a sclerotomal distribution. In fact, there is no specific ICD-10-CM diagnostic code to classify and define discogenic pain as a unique source of pain distinct from other recognized sources of chronic low back pain including facetogenic, neurocompressive including herniation and/or stenosis, sacroiliac, vertebrogenic, and psychogenic. All of these other sources have well-defined ICD-10-CM codes. Corresponding codes for discogenic pain remain absent from the diagnostic coding vernacular. The International Society for the Advancement of Spine Surgery (ISASS) has proposed a modernization of ICD-10-CM codes to specifically define pain associated with lumbar and lumbosacral degenerative disc disease. The proposed codes would also allow the pain to be characterized by location: lumbar region only, leg only, or both. Successful implementation of these codes would benefit both physicians and payers in distinguishing, tracking, and improving algorithms and treatments for discogenic pain associated with intervertebral disc degeneration. | 
    
|---|---|
| AbstractList | There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative disc disease, the specific diagnostic criteria lack clarity and fail to capture the primary components which include axial midline low back pain with or without non-radicular/non-sciatic referred leg pain in a sclerotomal distribution. In fact, there is no specific ICD-10-CM diagnostic code to classify and define discogenic pain as a unique source of pain distinct from other recognized sources of chronic low back pain including facetogenic, neurocompressive including herniation and/or stenosis, sacroiliac, vertebrogenic, and psychogenic. All of these other sources have well-defined ICD-10-CM codes. Corresponding codes for discogenic pain remain absent from the diagnostic coding vernacular. The International Society for the Advancement of Spine Surgery (ISASS) has proposed a modernization of ICD-10-CM codes to specifically define pain associated with lumbar and lumbosacral degenerative disc disease. The proposed codes would also allow the pain to be characterized by location: lumbar region only, leg only, or both. Successful implementation of these codes would benefit both physicians and payers in distinguishing, tracking, and improving algorithms and treatments for discogenic pain associated with intervertebral disc degeneration. There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative disc disease, the specific diagnostic criteria lack clarity and fail to capture the primary components which include axial midline low back pain with or without non-radicular/non-sciatic referred leg pain in a sclerotomal distribution. In fact, there is no specific ICD-10-CM diagnostic code to classify and define discogenic pain as a unique source of pain distinct from other recognized sources of chronic low back pain including facetogenic, neurocompressive including herniation and/or stenosis, sacroiliac, vertebrogenic, and psychogenic. All of these other sources have well-defined ICD-10-CM codes. Corresponding codes for discogenic pain remain absent from the diagnostic coding vernacular. The International Society for the Advancement of Spine Surgery (ISASS) has proposed a modernization of ICD-10-CM codes to specifically define pain associated with lumbar and lumbosacral degenerative disc disease. The proposed codes would also allow the pain to be characterized by location: lumbar region only, leg only, or both. Successful implementation of these codes would benefit both physicians and payers in distinguishing, tracking, and improving algorithms and treatments for discogenic pain associated with intervertebral disc degeneration.There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative disc disease, the specific diagnostic criteria lack clarity and fail to capture the primary components which include axial midline low back pain with or without non-radicular/non-sciatic referred leg pain in a sclerotomal distribution. In fact, there is no specific ICD-10-CM diagnostic code to classify and define discogenic pain as a unique source of pain distinct from other recognized sources of chronic low back pain including facetogenic, neurocompressive including herniation and/or stenosis, sacroiliac, vertebrogenic, and psychogenic. All of these other sources have well-defined ICD-10-CM codes. Corresponding codes for discogenic pain remain absent from the diagnostic coding vernacular. The International Society for the Advancement of Spine Surgery (ISASS) has proposed a modernization of ICD-10-CM codes to specifically define pain associated with lumbar and lumbosacral degenerative disc disease. The proposed codes would also allow the pain to be characterized by location: lumbar region only, leg only, or both. Successful implementation of these codes would benefit both physicians and payers in distinguishing, tracking, and improving algorithms and treatments for discogenic pain associated with intervertebral disc degeneration.  | 
    
| Audience | Academic | 
    
| Author | Lorio, Morgan P. Lewandrowski, Kai-Uwe Mekhail, Nagy Block, Jon E. Beall, Douglas P. Calodney, Aaron K.  | 
    
| AuthorAffiliation | 6 Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA; mekhain@ccf.org 2 Clinical Radiology of Oklahoma, 1800 S. Renaissance Blvd., Ste. 110, Edmond, OK 73013, USA; db@clinrad.org 1 Advanced Orthopedics, 499 E. Central Pkwy., Ste. 130, Altamonte Springs, FL 32701, USA; mloriomd@gmail.com 5 Independent Consultant, 2210 Jackson Street, Ste. 401, San Francisco, CA 94115, USA 3 Precision Spine Care, 2737 S. Broadway, Tyler, TX 75701, USA; aaroncalodney@me.com 4 Center for Advanced Spine Care of Southern Arizona, 4787 E. Camp Lowell Drive, Tucson, AZ 85712, USA; business@tucsonspine.com  | 
    
| AuthorAffiliation_xml | – name: 5 Independent Consultant, 2210 Jackson Street, Ste. 401, San Francisco, CA 94115, USA – name: 3 Precision Spine Care, 2737 S. Broadway, Tyler, TX 75701, USA; aaroncalodney@me.com – name: 1 Advanced Orthopedics, 499 E. Central Pkwy., Ste. 130, Altamonte Springs, FL 32701, USA; mloriomd@gmail.com – name: 6 Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA; mekhain@ccf.org – name: 2 Clinical Radiology of Oklahoma, 1800 S. Renaissance Blvd., Ste. 110, Edmond, OK 73013, USA; db@clinrad.org – name: 4 Center for Advanced Spine Care of Southern Arizona, 4787 E. Camp Lowell Drive, Tucson, AZ 85712, USA; business@tucsonspine.com  | 
    
| Author_xml | – sequence: 1 givenname: Morgan P. surname: Lorio fullname: Lorio, Morgan P. – sequence: 2 givenname: Douglas P. orcidid: 0000-0001-8340-696X surname: Beall fullname: Beall, Douglas P. – sequence: 3 givenname: Aaron K. surname: Calodney fullname: Calodney, Aaron K. – sequence: 4 givenname: Kai-Uwe orcidid: 0000-0001-7842-2914 surname: Lewandrowski fullname: Lewandrowski, Kai-Uwe – sequence: 5 givenname: Jon E. orcidid: 0000-0001-9954-8938 surname: Block fullname: Block, Jon E. – sequence: 6 givenname: Nagy surname: Mekhail fullname: Mekhail, Nagy  | 
    
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37240991$$D View this record in MEDLINE/PubMed | 
    
| BookMark | eNp9kk1v1DAQhiNUREvpiTuyxAUJtvgjcRIuqNoWqLQIhEAcLcc7znrl2CFOWu2_Z5YtdFsB9sHW-Jl3PK_9ODsIMUCWPWX0VIiavl73HRO0oBVnD7IjTstiludcHuztD7OTlNYUR1VwLumj7FCUPKd1zY6yzTlYF1xoybgC8lmPDsJIrt24Ioupa_RAzl0ysYXgDB678IZ8Ae1n3-Pgl-Sy670zmBRDIjZuYd2GmFwiOizJhbVgRncFZO6xiNGefNRBt9BhkSfZQ6t9gpOb9Tj79u7i6_zDbPHp_eX8bDEzeVmOs5ILSi0TeVHXQkrOeQO2bvTSssYwW0rBBQYFKysqoaKaWSEbAyVoWdSVFsfZq53uFHq9udbeq35wnR42ilG1NVHtmYj42x3eT00HS4M3HfRtStRO3T0JbqXaeIVinOeFpKjw4kZhiD8mSKPq0ELwXgeIU1K84pRyIUWO6PN76DpOQ0A7kGJ1XlQ1rW6pVntQLtiIhc1WVJ2VBc8rWXGJ1OlfKJxL6JzBX2Mdxu8kPNvv9E-Lvz8HAmwHmCGmNIBVxo2_HhuVnf-HfS_v5fzP7J_EE9lv | 
    
| CitedBy_id | crossref_primary_10_3390_healthcare11222956 crossref_primary_10_1186_s10020_024_00777_z crossref_primary_10_3390_jpm13061012 crossref_primary_10_1002_jsp2_70021 crossref_primary_10_3390_jcm13195915 crossref_primary_10_1186_s13018_024_04554_w crossref_primary_10_2147_JPR_S441180 crossref_primary_10_3390_bioengineering11060535 crossref_primary_10_3390_biology12101305 crossref_primary_10_1002_smll_202404963 crossref_primary_10_1007_s11916_024_01296_6  | 
    
| Cites_doi | 10.1097/01.brs.0000231761.73859.2c 10.1097/00007632-200007010-00005 10.1007/s00586-017-5292-3 10.1097/00007632-200001010-00019 10.1097/01.brs.0000162624.95262.73 10.1097/00007632-200112010-00007 10.1016/j.pmr.2014.01.006 10.1007/s13244-017-0584-z 10.1016/S0140-6736(18)30480-X 10.1097/BRS.0b013e31815a59a0 10.36076/ppj.2005/8/187 10.1016/S1042-3680(18)30701-0 10.1097/01.brs.0000146461.27105.2b 10.1302/0301-620X.74B5.1388173 10.1002/jor.23195 10.1038/s41584-022-00888-z 10.1016/j.eclinm.2023.101960 10.1097/00007632-199509150-00007 10.1016/j.pmrj.2010.09.006 10.1097/00007632-199711150-00012 10.1007/s00586-005-0892-8 10.36076/ppj.2001/4/308 10.1016/j.pain.2004.08.016 10.1007/s12195-009-0072-8 10.1016/j.rcl.2012.04.012 10.1097/01.brs.0000219946.25103.db 10.1016/S1529-9430(02)00563-6 10.1097/BRS.0b013e318263ba59 10.1002/jbm4.10180 10.1016/j.pain.2009.08.020 10.36076/ppj.2008/11/513 10.1016/j.spinee.2013.06.075 10.1016/S1529-9430(03)00068-8 10.1007/s00586-015-4359-2 10.1302/0301-620X.87B1.15708 10.1097/00007632-198303000-00012 10.1002/path.1108 10.1302/0301-620X.84B2.0840196 10.1097/00007632-198704000-00019 10.1016/j.spinee.2013.06.063 10.1016/S0030-5898(20)31644-8 10.1002/jor.23346 10.1007/s00586-023-07665-w 10.1097/00007632-197803000-00003 10.1097/01.brs.0000149186.63457.20 10.1097/00007632-198802000-00008 10.1097/00003086-199206000-00003 10.1016/S0033-8389(22)02550-7 10.1097/BRS.0b013e31815b9850 10.1016/j.spinee.2005.01.007 10.1097/00007632-199506000-00022 10.1002/jsp2.1231 10.1016/S0140-6736(97)02135-1 10.1148/rg.276065509 10.1097/00007632-199409000-00018 10.1136/bmj.322.7301.1511 10.1016/j.spinee.2012.12.003 10.3390/ijms24032728 10.1359/jbmr.2001.16.4.681 10.1097/00007632-199710150-00005 10.1111/j.1526-4637.2005.05034.x 10.1097/00007632-200103010-00006 10.1111/j.1469-7580.2010.01227.x 10.1111/j.1533-2500.2010.00408.x 10.1111/pme.12082 10.1097/00007632-200212010-00002 10.1002/jsp2.1123 10.1097/00007632-199509000-00007 10.1016/j.spinee.2011.07.021 10.1097/BRS.0b013e31815b64d2 10.1038/s41413-020-00125-x 10.3390/ijms24010208 10.1146/annurev.pu.12.050191.001041 10.1016/j.joca.2015.03.028 10.1186/s12891-016-1074-z 10.1097/01.brs.0000222032.52336.8e 10.1097/01.brs.0000201324.45537.46 10.1097/00007632-199409151-00005 10.1093/pm/pnab070 10.1097/00007632-200212150-00007 10.1002/jsp2.1230 10.1016/j.matbio.2018.03.019 10.1302/0301-620X.90B10.20910 10.1002/art.10585  | 
    
| ContentType | Journal Article | 
    
| Copyright | COPYRIGHT 2023 MDPI AG 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2023 by the authors. 2023  | 
    
| Copyright_xml | – notice: COPYRIGHT 2023 MDPI AG – notice: 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2023 by the authors. 2023  | 
    
| DBID | AAYXX CITATION NPM 8FE 8FH ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO GNUQQ HCIFZ LK8 M7P PHGZM PHGZT PIMPY PKEHL PQEST PQGLB PQQKQ PQUKI 7X8 5PM ADTOC UNPAY  | 
    
| DOI | 10.3390/jpm13050821 | 
    
| DatabaseName | CrossRef PubMed ProQuest SciTech Collection ProQuest Natural Science Journals ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials - QC Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central ProQuest Central Student SciTech Premium Collection Biological Sciences Biological Science Database ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition MEDLINE - Academic PubMed Central (Full Participant titles) Unpaywall for CDI: Periodical Content Unpaywall  | 
    
| DatabaseTitle | CrossRef PubMed Publicly Available Content Database ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Biological Science Collection ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection Biological Science Database ProQuest SciTech Collection ProQuest Central ProQuest One Applied & Life Sciences ProQuest One Academic UKI Edition Natural Science Collection ProQuest Central Korea Biological Science Collection ProQuest Central (New) ProQuest One Academic ProQuest One Academic (New) MEDLINE - Academic  | 
    
| DatabaseTitleList | CrossRef PubMed MEDLINE - Academic Publicly Available Content Database  | 
    
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: UNPAY name: Unpaywall url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/ sourceTypes: Open Access Repository – sequence: 3 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database  | 
    
| DeliveryMethod | fulltext_linktorsrc | 
    
| Discipline | Medicine | 
    
| EISSN | 2075-4426 | 
    
| ExternalDocumentID | 10.3390/jpm13050821 PMC10224560 A752486826 37240991 10_3390_jpm13050821  | 
    
| Genre | Journal Article | 
    
| GroupedDBID | 53G 5VS 8FE 8FH AADQD AAFWJ AAYXX ADBBV AFKRA AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BBNVY BCNDV BENPR BHPHI CCPQU CITATION DIK EMOBN GX1 HCIFZ HYE IAO IHR ITC KQ8 LK8 M48 M7P MODMG M~E OK1 PGMZT PHGZM PHGZT PIMPY PQGLB PROAC RPM GROUPED_DOAJ NPM ABUWG AZQEC DWQXO GNUQQ PKEHL PQEST PQQKQ PQUKI 7X8 PUEGO 5PM ADRAZ ADTOC IPNFZ RIG UNPAY  | 
    
| ID | FETCH-LOGICAL-c477t-72300f134599366222bef9badf1bc1f76323222317806e80a1f36bce7ea6598a3 | 
    
| IEDL.DBID | M48 | 
    
| ISSN | 2075-4426 | 
    
| IngestDate | Sun Oct 26 03:55:31 EDT 2025 Tue Sep 30 17:13:58 EDT 2025 Thu Sep 04 15:31:14 EDT 2025 Sun Jul 13 05:11:30 EDT 2025 Mon Oct 20 22:53:12 EDT 2025 Mon Oct 20 16:58:47 EDT 2025 Thu Jan 02 22:51:35 EST 2025 Thu Apr 24 23:07:08 EDT 2025 Thu Oct 16 04:45:59 EDT 2025  | 
    
| IsDoiOpenAccess | true | 
    
| IsOpenAccess | true | 
    
| IsPeerReviewed | true | 
    
| IsScholarly | true | 
    
| Issue | 5 | 
    
| Keywords | lumbar diagnosis pain reimbursement discogenic referred  | 
    
| Language | English | 
    
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). cc-by  | 
    
| LinkModel | DirectLink | 
    
| MergedId | FETCHMERGED-LOGICAL-c477t-72300f134599366222bef9badf1bc1f76323222317806e80a1f36bce7ea6598a3 | 
    
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23  | 
    
| ORCID | 0000-0001-9954-8938 0000-0001-7842-2914 0000-0001-8340-696X  | 
    
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.3390/jpm13050821 | 
    
| PMID | 37240991 | 
    
| PQID | 2819458908 | 
    
| PQPubID | 2032376 | 
    
| ParticipantIDs | unpaywall_primary_10_3390_jpm13050821 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10224560 proquest_miscellaneous_2820023634 proquest_journals_2819458908 gale_infotracmisc_A752486826 gale_infotracacademiconefile_A752486826 pubmed_primary_37240991 crossref_citationtrail_10_3390_jpm13050821 crossref_primary_10_3390_jpm13050821  | 
    
| PublicationCentury | 2000 | 
    
| PublicationDate | 2023-05-12 | 
    
| PublicationDateYYYYMMDD | 2023-05-12 | 
    
| PublicationDate_xml | – month: 05 year: 2023 text: 2023-05-12 day: 12  | 
    
| PublicationDecade | 2020 | 
    
| PublicationPlace | Switzerland | 
    
| PublicationPlace_xml | – name: Switzerland – name: Basel  | 
    
| PublicationTitle | Journal of personalized medicine | 
    
| PublicationTitleAlternate | J Pers Med | 
    
| PublicationYear | 2023 | 
    
| Publisher | MDPI AG MDPI  | 
    
| Publisher_xml | – name: MDPI AG – name: MDPI  | 
    
| References | ref_50 Simon (ref_74) 2014; 25 Carey (ref_30) 2000; 25 Brodke (ref_28) 2004; 86-A Kushchayev (ref_15) 2018; 9 Thurston (ref_33) 1983; 8 Kepler (ref_37) 2013; 13 Turk (ref_78) 2004; 4 Kurgansky (ref_83) 2002; 27 Derby (ref_91) 2005; 6 ref_95 Alini (ref_2) 2023; 6 Vanharanta (ref_94) 1987; 12 ref_18 Miller (ref_40) 1988; 13 Fields (ref_65) 2014; 14 Nachemson (ref_31) 1992; 279 Vo (ref_47) 2016; 34 Lyu (ref_45) 2021; 9 Weiler (ref_71) 2005; 30 Freemont (ref_62) 1997; 350 Calavia (ref_9) 2010; 217 Peng (ref_20) 2005; 87 Brisby (ref_73) 2006; 88 Johnson (ref_35) 2002; 46 Moneta (ref_69) 1994; 19 Groh (ref_67) 2021; 22 Buckwalter (ref_39) 1995; 20 Iatridis (ref_55) 2009; 2 DePalma (ref_82) 2011; 3 Shah (ref_89) 2005; 8 Kallewaard (ref_14) 2010; 10 Bogduk (ref_81) 2009; 147 Malik (ref_16) 2013; 13 ref_21 Choi (ref_54) 2018; 70 Fritz (ref_87) 2007; 27 White (ref_34) 1978; 3 Osti (ref_51) 1990; 15 Fournier (ref_66) 2020; 3 Moore (ref_22) 2007; 32 Boos (ref_38) 2002; 27 Osti (ref_52) 1992; 74 Kuslich (ref_23) 1991; 22 Diwan (ref_5) 2022; 6 Rhyne (ref_76) 1995; 20 Christenson (ref_32) 1977; 15 Roberts (ref_42) 2006; 88 Guzman (ref_29) 2001; 322 Hurri (ref_13) 2004; 112 Stefanakis (ref_56) 2012; 37 Freemont (ref_64) 2002; 197 Han (ref_12) 2023; 59 Rode (ref_26) 2002; 73 Bogduk (ref_57) 2012; 50 Bogduk (ref_3) 1991; 2 Fine (ref_7) 2023; 19 Stynes (ref_84) 2016; 17 Videman (ref_44) 2004; 29 Hadjipavlou (ref_10) 2008; 90 Peng (ref_19) 2006; 31 Shahraki (ref_70) 2016; 35 Ulrich (ref_53) 2007; 32 Bogduk (ref_4) 2013; 14 Lotz (ref_49) 2006; 88 Johnson (ref_63) 2001; 26 Schwarzer (ref_75) 1995; 20 Simpson (ref_60) 2001; 16 Stynes (ref_85) 2015; 25 Coppes (ref_61) 1997; 22 Inoue (ref_68) 2006; 31 Fardon (ref_6) 2001; 26 Burke (ref_72) 2002; 84 Wolfer (ref_92) 2008; 11 ref_80 Hartvigsen (ref_24) 2018; 391 Adams (ref_1) 2006; 31 Derby (ref_90) 2005; 5 Guyer (ref_86) 2003; 3 ref_88 Manchikanti (ref_17) 2001; 4 Vergroesen (ref_41) 2015; 23 Urban (ref_46) 2003; 5 Peng (ref_58) 2006; 15 Deyo (ref_27) 1991; 12 Johnson (ref_36) 2005; 30 Fazzalari (ref_48) 1997; 22 Haefeli (ref_11) 2006; 31 Griffith (ref_59) 2007; 32 Zehra (ref_25) 2018; 27 Fujii (ref_8) 2019; 3 Alamin (ref_93) 2011; 11 Adams (ref_43) 2000; 25 (ref_77) 1994; 19 Boswell (ref_79) 2007; 10  | 
    
| References_xml | – volume: 31 start-page: 2151 year: 2006 ident: ref_1 article-title: What is intervertebral disc degeneration, and what causes it? publication-title: Spine doi: 10.1097/01.brs.0000231761.73859.2c – volume: 25 start-page: 1625 year: 2000 ident: ref_43 article-title: Mechanical Initiation of Intervertebral Disc Degeneration publication-title: Spine doi: 10.1097/00007632-200007010-00005 – volume: 27 start-page: 2 year: 2018 ident: ref_25 article-title: Structural vertebral endplate nomenclature and etiology: A study by the ISSLS Spinal Phenotype Focus Group publication-title: Eur. Spine J. doi: 10.1007/s00586-017-5292-3 – volume: 25 start-page: 115 year: 2000 ident: ref_30 article-title: Beyond the good prognosis. Examination of an inception cohort of patients with chronic low back pain publication-title: Spine doi: 10.1097/00007632-200001010-00019 – volume: 30 start-page: 1139 year: 2005 ident: ref_36 article-title: Human Intervertebral Disc Aggrecan Inhibits Endothelial Cell Adhesion and Cell Migration In Vitro publication-title: Spine doi: 10.1097/01.brs.0000162624.95262.73 – volume: 26 start-page: 2550 year: 2001 ident: ref_63 article-title: Immunohistochemical Detection of Schwann Cells in Innervated and Vascularized Human Intervertebral Discs publication-title: Spine doi: 10.1097/00007632-200112010-00007 – volume: 25 start-page: 305 year: 2014 ident: ref_74 article-title: Discogenic Low Back Pain publication-title: Phys. Med. Rehabil. Clin. N. Am. doi: 10.1016/j.pmr.2014.01.006 – ident: ref_80 – volume: 9 start-page: 253 year: 2018 ident: ref_15 article-title: ABCs of the degenerative spine publication-title: Insights Imaging doi: 10.1007/s13244-017-0584-z – volume: 391 start-page: 2356 year: 2018 ident: ref_24 article-title: What low back pain is and why we need to pay attention publication-title: Lancet doi: 10.1016/S0140-6736(18)30480-X – volume: 32 start-page: E708 year: 2007 ident: ref_59 article-title: Modified Pfirrmann Grading System for Lumbar Intervertebral Disc Degeneration publication-title: Spine doi: 10.1097/BRS.0b013e31815a59a0 – volume: 8 start-page: 187 year: 2005 ident: ref_89 article-title: Discography as a diagnostic test for spinal pain: A systematic and narrative review publication-title: Pain. Physician doi: 10.36076/ppj.2005/8/187 – volume: 2 start-page: 791 year: 1991 ident: ref_3 article-title: The Lumbar Disc and Low Back Pain publication-title: Neurosurg. Clin. N. Am. doi: 10.1016/S1042-3680(18)30701-0 – volume: 29 start-page: 2668 year: 2004 ident: ref_44 article-title: The Occurrence of Anular Tears and Their Relation to Lifetime Back Pain History: A Cadaveric Study Using Barium Sulfate Discography publication-title: Spine doi: 10.1097/01.brs.0000146461.27105.2b – volume: 74 start-page: 678 year: 1992 ident: ref_52 article-title: Annular tears and disc degeneration in the lumbar spine. A post-mortem study of 135 discs publication-title: J. Bone Jt. Surg. doi: 10.1302/0301-620X.74B5.1388173 – volume: 34 start-page: 1289 year: 2016 ident: ref_47 article-title: Molecular mechanisms of biological aging in intervertebral discs publication-title: J. Orthop. Res. doi: 10.1002/jor.23195 – volume: 19 start-page: 136 year: 2023 ident: ref_7 article-title: Intervertebral disc degeneration and osteoarthritis: A common molecular disease spectrum publication-title: Nat. Rev. Rheumatol. doi: 10.1038/s41584-022-00888-z – ident: ref_88 – volume: 59 start-page: 101960 year: 2023 ident: ref_12 article-title: Low back pain of disc, sacroiliac joint, or facet joint origin: A diagnostic accuracy systematic review publication-title: Eclinicalmedicine doi: 10.1016/j.eclinm.2023.101960 – volume: 20 start-page: 1997 year: 1995 ident: ref_76 article-title: Outcome of Unoperated Discogram-Positive Low Back Pain publication-title: Spine doi: 10.1097/00007632-199509150-00007 – volume: 3 start-page: 33 year: 2011 ident: ref_82 article-title: Does the Location of Low Back Pain Predict Its Source? publication-title: PMR doi: 10.1016/j.pmrj.2010.09.006 – volume: 22 start-page: 2641 year: 1997 ident: ref_48 article-title: Pathogenesis of Tears of the Anulus Investigated by Multiple-Level Transaxial Analysis of the T12-L1 Disc publication-title: Spine doi: 10.1097/00007632-199711150-00012 – volume: 15 start-page: 583 year: 2006 ident: ref_58 article-title: The pathogenesis and clinical significance of a high-intensity zone (HIZ) of lumbar intervertebral disc on MR imaging in the patient with discogenic low back pain publication-title: Eur. Spine J. doi: 10.1007/s00586-005-0892-8 – volume: 4 start-page: 308 year: 2001 ident: ref_17 article-title: Evaluation of the relative contributions of various structures in chronic low back pain publication-title: Pain Physician doi: 10.36076/ppj.2001/4/308 – volume: 112 start-page: 225 year: 2004 ident: ref_13 article-title: Discogenic pain publication-title: Pain doi: 10.1016/j.pain.2004.08.016 – volume: 2 start-page: 437 year: 2009 ident: ref_55 article-title: Localized Intervertebral Disc Injury Leads to Organ Level Changes in Structure, Cellularity, and Biosynthesis publication-title: Cell. Mol. Bioeng. doi: 10.1007/s12195-009-0072-8 – volume: 50 start-page: 613 year: 2012 ident: ref_57 article-title: Degenerative Joint Disease of the Spine publication-title: Radiol. Clin. N. Am. doi: 10.1016/j.rcl.2012.04.012 – volume: 31 start-page: 1433 year: 2006 ident: ref_68 article-title: Exposure of the Nucleus Pulposus to the Outside of the Anulus Fibrosus Induces Nerve Injury and Regeneration of the Afferent Fibers Innervating the Lumbar Intervertebral Discs in Rats publication-title: Spine doi: 10.1097/01.brs.0000219946.25103.db – volume: 15 start-page: 762 year: 1990 ident: ref_51 article-title: 1990 Volvo Award in Experimental Studies: Anulus Tears and Intervertebral Disc Degeneration. An experimental study using an animal model publication-title: Spine – volume: 3 start-page: 11S year: 2003 ident: ref_86 article-title: Lumbar discography publication-title: Spine J. doi: 10.1016/S1529-9430(02)00563-6 – volume: 37 start-page: 1883 year: 2012 ident: ref_56 article-title: Annulus Fissures Are Mechanically and Chemically Conducive to the Ingrowth of Nerves and Blood Vessels publication-title: Spine doi: 10.1097/BRS.0b013e318263ba59 – volume: 3 start-page: e10180 year: 2019 ident: ref_8 article-title: Discogenic Back Pain: Literature Review of Definition, Diagnosis, and Treatment publication-title: JBMR Plus doi: 10.1002/jbm4.10180 – volume: 86-A start-page: 1810 year: 2004 ident: ref_28 article-title: Nonoperative management of low back pain and lumbar disc degeneration publication-title: J. Bone Joint Surg. Am. – volume: 147 start-page: 17 year: 2009 ident: ref_81 article-title: On the definitions and physiology of back pain, referred pain, and radicular pain publication-title: Pain doi: 10.1016/j.pain.2009.08.020 – volume: 11 start-page: 513 year: 2008 ident: ref_92 article-title: Systematic review of lumbar provocation discography in asymptomatic subjects with a meta-analysis of false-positive rates publication-title: Pain Physician doi: 10.36076/ppj.2008/11/513 – volume: 14 start-page: 513 year: 2014 ident: ref_65 article-title: Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc publication-title: Spine J. doi: 10.1016/j.spinee.2013.06.075 – volume: 4 start-page: 1 year: 2004 ident: ref_78 article-title: Understanding pain sufferers: The role of cognitive processes publication-title: Spine J. doi: 10.1016/S1529-9430(03)00068-8 – volume: 25 start-page: 2734 year: 2015 ident: ref_85 article-title: Reliability among clinicians diagnosing low back-related leg pain publication-title: Eur. Spine J. doi: 10.1007/s00586-015-4359-2 – volume: 87 start-page: 62 year: 2005 ident: ref_20 article-title: The pathogenesis of discogenic low back pain publication-title: J. Bone Joint Surg. Br. doi: 10.1302/0301-620X.87B1.15708 – volume: 8 start-page: 199 year: 1983 ident: ref_33 article-title: Normal Kinematics of the Lumbar Spine and Pelvis publication-title: Spine doi: 10.1097/00007632-198303000-00012 – volume: 197 start-page: 286 year: 2002 ident: ref_64 article-title: Nerve growth factor expression and innervation of the painful intervertebral disc publication-title: J. Pathol. doi: 10.1002/path.1108 – volume: 84 start-page: 196 year: 2002 ident: ref_72 article-title: Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators publication-title: J. Bone Jt. Surg. doi: 10.1302/0301-620X.84B2.0840196 – volume: 12 start-page: 295 year: 1987 ident: ref_94 article-title: The Relationship of Pain Provocation to Lumbar Disc Deterioration as Seen by CT/Discography publication-title: Spine doi: 10.1097/00007632-198704000-00019 – volume: 13 start-page: 1675 year: 2013 ident: ref_16 article-title: Diagnostic criteria and treatment of discogenic pain: A systematic review of recent clinical literature publication-title: Spine J. doi: 10.1016/j.spinee.2013.06.063 – volume: 22 start-page: 181 year: 1991 ident: ref_23 article-title: The tissue origin of low back pain and sciatica: A report of pain response to tissue stimulation during operations on the lumbar spine using local anesthesia publication-title: Orthop. Clin. N. Am. doi: 10.1016/S0030-5898(20)31644-8 – volume: 35 start-page: 113 year: 2016 ident: ref_70 article-title: Prediction of clinically relevant initiation and progression of tears within annulus fibrosus publication-title: J. Orthop. Res. doi: 10.1002/jor.23346 – ident: ref_95 doi: 10.1007/s00586-023-07665-w – volume: 3 start-page: 12 year: 1978 ident: ref_34 article-title: The Basic Kinematics of the Human Spine. A review of past and current knowledge publication-title: Spine doi: 10.1097/00007632-197803000-00003 – volume: 30 start-page: 44 year: 2005 ident: ref_71 article-title: Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy Controls publication-title: Spine doi: 10.1097/01.brs.0000149186.63457.20 – volume: 13 start-page: 173 year: 1988 ident: ref_40 article-title: Lumbar disc degeneration: Correlation with age, sex, and spine level in 600 autopsy specimens publication-title: Spine doi: 10.1097/00007632-198802000-00008 – volume: 279 start-page: 8 year: 1992 ident: ref_31 article-title: Newest knowledge of low back pain. A critical look publication-title: Clin. Orthop. doi: 10.1097/00003086-199206000-00003 – volume: 88 start-page: 10 year: 2006 ident: ref_42 article-title: Histology and pathology of the human intervertebral disc publication-title: J. Bone Joint Surg. Am. – volume: 15 start-page: 133 year: 1977 ident: ref_32 article-title: The radiologic study of the normal spine: Cervical, thoracic, lumbar, and sacral publication-title: Radiol. Clin. N. Am. doi: 10.1016/S0033-8389(22)02550-7 – volume: 32 start-page: 2812 year: 2007 ident: ref_53 article-title: Repeated Disc Injury Causes Persistent Inflammation publication-title: Spine doi: 10.1097/BRS.0b013e31815b9850 – volume: 5 start-page: 389 year: 2005 ident: ref_90 article-title: Comparison of discographic findings in asymptomatic subject discs and the negative discs of chronic LBP patients: Can discography distinguish asymptomatic discs among morphologically abnormal discs? publication-title: Spine J. doi: 10.1016/j.spinee.2005.01.007 – volume: 20 start-page: 1307 year: 1995 ident: ref_39 article-title: Aging and Degeneration of the Human Intervertebral Disc publication-title: Spine doi: 10.1097/00007632-199506000-00022 – volume: 6 start-page: e1231 year: 2022 ident: ref_5 article-title: Intervertebral disc degeneration and how it leads to low back pain publication-title: JOR Spine doi: 10.1002/jsp2.1231 – volume: 10 start-page: 7 year: 2007 ident: ref_79 article-title: Interventional techniques: Evidence-based practice guidelines in the management of chronic spinal pain publication-title: Pain. Physician – volume: 350 start-page: 178 year: 1997 ident: ref_62 article-title: Nerve ingrowth into diseased intervertebral disc in chronic back pain publication-title: Lancet doi: 10.1016/S0140-6736(97)02135-1 – volume: 27 start-page: 1751 year: 2007 ident: ref_87 article-title: Management of Chronic Low Back Pain: Rationales, Principles, and Targets of Imaging-guided Spinal Injections publication-title: RadioGraphics doi: 10.1148/rg.276065509 – volume: 88 start-page: 76 year: 2006 ident: ref_49 article-title: Innervation, Inflammation, and Hypermobility May Characterize Pathologic Disc Degeneration: Review of Animal Model Data publication-title: J. Bone Jt. Surg. – volume: 19 start-page: 1968 year: 1994 ident: ref_69 article-title: Reported Pain During Lumbar Discography As a Function of Anular Ruptures and Disc Degeneration publication-title: Spine doi: 10.1097/00007632-199409000-00018 – volume: 322 start-page: 1511 year: 2001 ident: ref_29 article-title: Multidisciplinary rehabilitation for chronic low back pain: Systematic review publication-title: BMJ doi: 10.1136/bmj.322.7301.1511 – volume: 13 start-page: 318 year: 2013 ident: ref_37 article-title: The molecular basis of intervertebral disc degeneration publication-title: Spine J. doi: 10.1016/j.spinee.2012.12.003 – ident: ref_21 doi: 10.3390/ijms24032728 – volume: 16 start-page: 681 year: 2001 ident: ref_60 article-title: Intervertebral Disc Disorganization Is Related to Trabecular Bone Architecture in the Lumbar Spine publication-title: J. Bone Miner. Res. doi: 10.1359/jbmr.2001.16.4.681 – volume: 22 start-page: 2342 year: 1997 ident: ref_61 article-title: Innervation of "Painful" Lumbar Discs publication-title: Spine doi: 10.1097/00007632-199710150-00005 – volume: 6 start-page: 213 year: 2005 ident: ref_91 article-title: Pressure-Controlled Lumbar Discography in Volunteers Without Low Back Symptoms publication-title: Pain Med. doi: 10.1111/j.1526-4637.2005.05034.x – volume: 26 start-page: E93 year: 2001 ident: ref_6 article-title: Nomenclature and classification of lumbar disc pathology. Recommendations of the Combined Task Forces of the North American Spine Society, American Society of Spine Radiology, and American Society of Neuroradiology publication-title: Spine doi: 10.1097/00007632-200103010-00006 – volume: 217 start-page: 1 year: 2010 ident: ref_9 article-title: Intervertebral disc, sensory nerves and neurotrophins: Who is who in discogenic pain? publication-title: J. Anat. doi: 10.1111/j.1469-7580.2010.01227.x – volume: 10 start-page: 560 year: 2010 ident: ref_14 article-title: 15. Discogenic low back pain publication-title: Pain Pract. doi: 10.1111/j.1533-2500.2010.00408.x – ident: ref_50 – volume: 88 start-page: 68 year: 2006 ident: ref_73 article-title: Pathology and possible mechanisms of nervous system response to disc degeneration publication-title: J. Bone Joint Surg. Am. – volume: 14 start-page: 813 year: 2013 ident: ref_4 article-title: Lumbar Discogenic Pain: State-of-the-Art Review publication-title: Pain Med. doi: 10.1111/pme.12082 – volume: 27 start-page: 2631 year: 2002 ident: ref_38 article-title: Classification of Age-Related Changes in Lumbar Intervertebral Discs publication-title: Spine doi: 10.1097/00007632-200212010-00002 – volume: 3 start-page: e1123 year: 2020 ident: ref_66 article-title: Vascularization of the human intervertebral disc: A scoping review publication-title: JOR Spine doi: 10.1002/jsp2.1123 – volume: 20 start-page: 1878 year: 1995 ident: ref_75 article-title: The Prevalence and Clinical Features of Internal Disc Disruption in Patients With Chronic Low Back Pain publication-title: Spine doi: 10.1097/00007632-199509000-00007 – volume: 11 start-page: 756 year: 2011 ident: ref_93 article-title: Provocative lumbar discography versus functional anesthetic discography: A comparison of the results of two different diagnostic techniques in 52 patients with chronic low back pain publication-title: Spine J. doi: 10.1016/j.spinee.2011.07.021 – volume: 32 start-page: 2797 year: 2007 ident: ref_22 article-title: The Natural History of Age-related Disc Degeneration. The pathology and sequelae of tears publication-title: Spine doi: 10.1097/BRS.0b013e31815b64d2 – volume: 9 start-page: 7 year: 2021 ident: ref_45 article-title: Painful intervertebral disc degeneration and inflammation: From laboratory evidence to clinical interventions publication-title: Bone Res. doi: 10.1038/s41413-020-00125-x – ident: ref_18 doi: 10.3390/ijms24010208 – volume: 12 start-page: 141 year: 1991 ident: ref_27 article-title: Cost, controversy, crisis: Low back pain and the health of the public publication-title: Annu. Rev. Public Health doi: 10.1146/annurev.pu.12.050191.001041 – volume: 23 start-page: 1057 year: 2015 ident: ref_41 article-title: Mechanics and biology in intervertebral disc degeneration: A vicious circle publication-title: Osteoarthr. Cartil. doi: 10.1016/j.joca.2015.03.028 – volume: 17 start-page: 1 year: 2016 ident: ref_84 article-title: Classification of patients with low back-related leg pain: A systematic review publication-title: BMC Musculoskelet. Disord. doi: 10.1186/s12891-016-1074-z – volume: 31 start-page: 1522 year: 2006 ident: ref_11 article-title: The Course of Macroscopic Degeneration in the Human Lumbar Intervertebral Disc publication-title: Spine doi: 10.1097/01.brs.0000222032.52336.8e – volume: 31 start-page: 560 year: 2006 ident: ref_19 article-title: Possible Pathogenesis of Painful Intervertebral Disc Degeneration publication-title: Spine doi: 10.1097/01.brs.0000201324.45537.46 – volume: 19 start-page: 2041S year: 1994 ident: ref_77 article-title: Studying the Natural History of Back Pain publication-title: Spine doi: 10.1097/00007632-199409151-00005 – volume: 22 start-page: 1281 year: 2021 ident: ref_67 article-title: Innervation of the Human Intervertebral Disc: A Scoping Review publication-title: Pain. Med. doi: 10.1093/pm/pnab070 – volume: 27 start-page: 2776 year: 2002 ident: ref_83 article-title: Disc Stimulation and Patterns of Referred Pain publication-title: Spine doi: 10.1097/00007632-200212150-00007 – volume: 6 start-page: e1230 year: 2023 ident: ref_2 article-title: An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics publication-title: JOR Spine doi: 10.1002/jsp2.1230 – volume: 70 start-page: 102 year: 2018 ident: ref_54 article-title: A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis publication-title: Matrix Biol. doi: 10.1016/j.matbio.2018.03.019 – volume: 5 start-page: 120 year: 2003 ident: ref_46 article-title: Degeneration of the intervertebral disc publication-title: Thromb. Haemost. – volume: 90 start-page: 1261 year: 2008 ident: ref_10 article-title: The pathophysiology of disc degeneration: A critical review publication-title: J. Bone Joint Surg. Br. doi: 10.1302/0301-620X.90B10.20910 – volume: 73 start-page: 18 year: 2002 ident: ref_26 article-title: Coding standards remain AHIMA priority in 2002 publication-title: J. AHIMA – volume: 46 start-page: 2658 year: 2002 ident: ref_35 article-title: Human intervertebral disc aggrecan inhibits nerve growth in vitro publication-title: Arthritis Rheum. doi: 10.1002/art.10585  | 
    
| SSID | ssj0000852260 | 
    
| Score | 2.353416 | 
    
| Snippet | There is an enormous body of literature that has identified the intervertebral disc as a potent pain generator. However, with regard to lumbar degenerative... | 
    
| SourceID | unpaywall pubmedcentral proquest gale pubmed crossref  | 
    
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source  | 
    
| StartPage | 821 | 
    
| SubjectTerms | Back pain Backache Biomechanics Bone surgery Care and treatment Degeneration Degenerative disc disease Information management Intervertebral discs Low back pain Neural coding Opinion Pain Patients Precision medicine Spine (lumbar) Stenosis Surgeons  | 
    
| SummonAdditionalLinks | – databaseName: ProQuest Central dbid: BENPR link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1tSxwxEB7sCW2_iH2zW21JwVIoBHezyb4Uitiq2NIeIhX8tmSzCd1y7l29O8R_78y-eSvFr5vZJWwmk2eSJ88A7Arl4jwXkjuXhFziGsO1EzlPExMXSkbaFjXbYhydnMsfF-piDcbdXRiiVXYxsQ7UxdTQHvkeHfhIlaR-sj_7x6lqFJ2udiU0dFtaofhSS4w9gnVBylgjWP96ND4963ddEGAg3vCbi3oh5vt7f2eXGMYRpohgsDTdD9ArK9R99uSTZTXTN9d6MllZmo43YaPFlOygcYJnsGar5_D4V3tq_gJuDq2r60AwRHvstFFSZbQDy34uL3N9xQ7LuZmiK5UGm8vqMztD_Mhrog37vsI5Zwhx0bhm55VzpquCNfLHGDNZKzE6YXeUmpdwfnz0-9sJb0sucCPjeMFjzEh8F4RSIW6JIgQPuXVprgsX5CZwGIwEHc0g6Ej8yCa-DlwY5cbGVkcqTXT4CkbVtLKvgQX4REnaY9KFtM5PrXSpCjHhVAWiCufBp-5vZ6bVI6eyGJMM8xIammxlaDzY7Y1njQzH_80-0rBlNDnxW0a3dwywRyRzlR3ESsgkwpTKg52BJU4qM2zuBj5rJ_U8u3NBD973zfQmEdUqO12SjahF-UPpwVbjJ32HwxjhE-JxD5KBB_UGJPU9bKnKP7Xkdy38h-DUgw-9sz30I9483P9teCqwl8SCCMQOjBZXS_sWwdUif9fOmFvLDCQS priority: 102 providerName: ProQuest – databaseName: Unpaywall dbid: UNPAY link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bi9QwFD7oLKgv3i_VVSKsCEK3bS5t6osMrssquiziwPpUkjbB6mxn2Jkq66_3pM3UmUFEfG1OS9qcnPOd5OsXgD0qbKY15aG1koUcc0yoLNVhLsusEjxVpurYFsfp0YS_OxWnfsFt4WmVWIrXXZCmmM9CjjkkSlgkIkmTaF7ZV9_9SlKSSiYlQhZ2GXZSgVh8BDuT45PxZ3ei3Ore_qc8hrV99HV-hiEbIQlNNtLQdjBey0bbTMmrbTNXFz_UdLqWhg5vQLF6gZ598m2_Xer98ueWtuP_v-FNuO4RKhn3LnULLpnmNlz54Pfg78DFgbHdqRIEsSM56XVZiVvPJe_bM63OyUG9KGfomHWJzXXzknxENBp2tB3ydo3BThAwo3HH9asXRDUV6cWUMQITL1g6Jb8JOndhcvjm0-uj0B_gEJY8y5ZhhvVNbBPGBaKgNEUooo3NtapsosvEYmijbqMHIYyMUyNjlViW6tJkRuFwSsXuwaiZNeYBkASvCO5WrFTFjY1zw20uGJavokKMYgN4sRrPovTq5u6QjWmBVY4b_GJt8APYG4znvajHn82eO8co3FTHZ5XK_7GAPXKiWcU4E5TLFAu0AHY3LHGKlpvNK9cqfIhYFG4HkwuZxzKAp0Ozu9PR3hoza50N7ST-GQ_gfu-JQ4dZhmAM0X0AcsNHBwMnHL7Z0tRfOgHxTkYQoW4AzwZ3_tuHePiPdo_gGsXuOnJFQndhtDxvzWPEbEv9xE_MX6m1Oww priority: 102 providerName: Unpaywall  | 
    
| Title | Defining the Patient with Lumbar Discogenic Pain: Real-World Implications for Diagnosis and Effective Clinical Management | 
    
| URI | https://www.ncbi.nlm.nih.gov/pubmed/37240991 https://www.proquest.com/docview/2819458908 https://www.proquest.com/docview/2820023634 https://pubmed.ncbi.nlm.nih.gov/PMC10224560 https://www.mdpi.com/2075-4426/13/5/821/pdf?version=1683881613  | 
    
| UnpaywallVersion | publishedVersion | 
    
| Volume | 13 | 
    
| hasFullText | 1 | 
    
| inHoldings | 1 | 
    
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: KQ8 dateStart: 20110101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: DIK dateStart: 20110101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVFQY databaseName: GFMER Free Medical Journals customDbUrl: eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: GX1 dateStart: 20110101 isFulltext: true titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php providerName: Geneva Foundation for Medical Education and Research – providerCode: PRVHPJ databaseName: ROAD : Directory of Open Access Scholarly Resources customDbUrl: eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: M~E dateStart: 20110101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVAQN databaseName: PubMed Central customDbUrl: eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: RPM dateStart: 20110101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: http://www.proquest.com/pqcentral?accountid=15518 eissn: 2075-4426 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: BENPR dateStart: 20110101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVFZP databaseName: Scholars Portal Journals: Open Access customDbUrl: eissn: 2075-4426 dateEnd: 20250831 omitProxy: true ssIdentifier: ssj0000852260 issn: 2075-4426 databaseCode: M48 dateStart: 20110301 isFulltext: true titleUrlDefault: http://journals.scholarsportal.info providerName: Scholars Portal  | 
    
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1tb9MwED6NTQK-IN7JGJWRhpCQAolj5wUJocI2BmJVNVGp-xQ5ia1lytLSF0H_PXdJGppq2lf7HDn22fecfX4O4JBLEyQJF7YxoWcLtDG2MjyxozANMil8pbMq2mLgn47Ej7Ec78A6GWczgPMbXTvKJzWaFe___l59xgX_iTxOdNk_XE2vcSdGpEEPyvfQREWUw-GswflXdTAWwgw6b-FoIm2BZql-q7fdvmOdtvfoDSO1HUB5b1lO1eqPKooN63TyEB40sJL1az14BDu6fAx3z5qL8yewOtKmSgXBEPCxYU2myugQlv1cXidqxo7yeTpBbcpTrM7Lj-wcIaRdxdqw7xth5wxRLgpXAXr5nKkyYzUDMm6brGEZLdj_qJqnMDo5_vX11G6yLtipCIKFHaBT4hjXExKhi-8jfki0iRKVGTdJXYP7EafbGcQdoePr0FGu8fwk1YFWvoxC5T2D3XJS6hfAXCyRgo6ZVCa0cSItTCQ99DllhsDCWPBuPdpx2lCSU2aMIkbXhKYm3pgaCw5b4WnNxHGz2Fuatpg0Br-VquaZAfaImK7ifiC5CH30qiw46Ejiukq71euJj9dqGdO1o5Bh5IQWvG6rqSXFqpV6siQZXvHye8KC57WetB32AlLPCHsZdjSoFSC2725NmV9WrN8V9x_iUwvetMp220Ds3_57L-E-x15SIITLD2B3MVvqV4ivFkkP9r4cD4bnPbjzbez2qpWEZaPBsH_xD1e_JX4 | 
    
| linkProvider | Scholars Portal | 
    
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1ta9swED66FtZ9GXuft27ToGUwMLUl-W1QRre0JGsaSmmh3zxZlphH6mRNQsmf22_byZbduIx-69foYoTudPecdHoOYJsGOsoyyl2tY-ZyjDGu0DRzk1hGecBDofKq2mIU9s_5j4vgYg3-Nm9hTFll4xMrR51PpDkj3zUXPjyIEy_-Ov3jmq5R5na1aaEhbGuFfK-iGLMPO47U8hpTuNneoIf63qH08ODse9-1XQZcyaNo7kYIwj3tMx5gqA5DjJeZ0kkmcu1n0te4_6i5jcA4G3uhij3haxZmUkVKhEESC4bffQAbnPEEk7-Nbwejk9P2lAcBDeIbr34YyFji7f6eXmLYQFhE_U4ovB0QViLi7WrNzUU5FctrMR6vhMLDJ_DYYliyXxvdU1hT5TN4eGxv6Z_Dsqd01XeCILokJzVzKzEnvmS4uMzEFekVMzlB0y0kDhflF3KKeNWtCnvIYKXGnSCkRuGqGrCYEVHmpKZbRh9NLKXpmNyU8LyA83tZ_JewXk5K9RqIj78E3JxpiZwr7SWK6yRgmOAGOaIY7cDnZrVTafnPTRuOcYp5kFFNuqIaB7Zb4WlN-_F_sU9GbalxBvgtKeybBpyRodVK96OA8jjEFM6BrY4kbmLZHW4Un1onMktvTN6Bj-2w-acpjCvVZGFkaNUEgHEHXtV20k6YRQjXEP87EHcsqBUw1OLdkbL4VVGMV0SDCIYd2GmN7a6FeHP3_D_AZv_seJgOB6Ojt_CI4oxNBYZPt2B9frVQ7xDYzbP3dvcQ-HnfG_Yf-dpfSg | 
    
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3da9swED-6Frq9jH3PW7dp0DIYmNiy5I9BGd3S0KxdCGWFvnmyLDGP1MmahJJ_cX_VTrbsxmX0ra_RxQjd1-90pzuAXcp1lGWUuVrHgcvQx7hC08xNYhnlnIVC5VW1xSg8OmPfzvn5Bvxt3sKYssrGJlaGOp9Kc0feMwkfxuPEi3valkWM-4PPsz-umSBlMq3NOA1hxyzk-1W7MfvI41itrjCcm-8P-8j7PUoHhz--Hrl24oArWRQt3AgBuaf9gHF022GIvjNTOslErv1M-hp1kZrMBPrc2AtV7AlfB2EmVaREyJNYBPjde7Blkl9oJLa-HI7Gp-2ND4IbxDpe_UgwCBKv93t2gS4EIRL1O27xpnNY8443KzfvL8uZWF2JyWTNLQ4ewUOLZ8lBLYCPYUOVT2D7u83YP4VVX-lqBgVBpEnGdRdXYm5_ycnyIhOXpF_M5RTFuJC4XJSfyCliV7cq8iHDtXp3gvAaiavKwGJORJmTuvUy2mti25tOyHU5zzM4u5PDfw6b5bRUL4H4-Atn5n5L5ExpL1FMJzzAYJfniGi0Ax-b006l7YVuRnJMUoyJDGvSNdY4sNsSz-oWIP8n-2DYlhrDgN-Swr5vwB2ZFlvpQcQpi0MM5xzY6VCiQsvucsP41BqUeXot_g68b5fNP02RXKmmS0NDq4EAAXPgRS0n7YaDCKEbxgIOxB0JaglMm_HuSln8qtqNV00HERg7sNcK220H8er2_b-DbVTc9GQ4On4NDyhu2BRj-HQHNheXS_UGMd4ie2uVh8DPu9bXf1sfY3k | 
    
| linkToUnpaywall | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bi9QwFD7oLKgv3i_VVSKsCEK3bS5t6osMrssquiziwPpUkjbB6mxn2Jkq66_3pM3UmUFEfG1OS9qcnPOd5OsXgD0qbKY15aG1koUcc0yoLNVhLsusEjxVpurYFsfp0YS_OxWnfsFt4WmVWIrXXZCmmM9CjjkkSlgkIkmTaF7ZV9_9SlKSSiYlQhZ2GXZSgVh8BDuT45PxZ3ei3Ore_qc8hrV99HV-hiEbIQlNNtLQdjBey0bbTMmrbTNXFz_UdLqWhg5vQLF6gZ598m2_Xer98ueWtuP_v-FNuO4RKhn3LnULLpnmNlz54Pfg78DFgbHdqRIEsSM56XVZiVvPJe_bM63OyUG9KGfomHWJzXXzknxENBp2tB3ydo3BThAwo3HH9asXRDUV6cWUMQITL1g6Jb8JOndhcvjm0-uj0B_gEJY8y5ZhhvVNbBPGBaKgNEUooo3NtapsosvEYmijbqMHIYyMUyNjlViW6tJkRuFwSsXuwaiZNeYBkASvCO5WrFTFjY1zw20uGJavokKMYgN4sRrPovTq5u6QjWmBVY4b_GJt8APYG4znvajHn82eO8co3FTHZ5XK_7GAPXKiWcU4E5TLFAu0AHY3LHGKlpvNK9cqfIhYFG4HkwuZxzKAp0Ozu9PR3hoza50N7ST-GQ_gfu-JQ4dZhmAM0X0AcsNHBwMnHL7Z0tRfOgHxTkYQoW4AzwZ3_tuHePiPdo_gGsXuOnJFQndhtDxvzWPEbEv9xE_MX6m1Oww | 
    
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Defining+the+Patient+with+Lumbar+Discogenic+Pain%3A+Real-World+Implications+for+Diagnosis+and+Effective+Clinical+Management&rft.jtitle=Journal+of+personalized+medicine&rft.au=Lorio%2C+Morgan+P&rft.au=Beall%2C+Douglas+P&rft.au=Calodney%2C+Aaron+K&rft.au=Lewandrowski%2C+Kai-Uwe&rft.date=2023-05-12&rft.pub=MDPI+AG&rft.issn=2075-4426&rft.eissn=2075-4426&rft.volume=13&rft.issue=5&rft_id=info:doi/10.3390%2Fjpm13050821&rft.externalDocID=A752486826 | 
    
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2075-4426&client=summon | 
    
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2075-4426&client=summon | 
    
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2075-4426&client=summon |