Systems analysis of protective immune responses to RTS,S malaria vaccination in humans - Kazmin, Dmitri; Nakaya, Helder I.; Lee, Eva K.; Johnson, Matthew J.; van der Most, Robbert; van den Berg, Robert A.; Ballou, W. Ripley; Jongert, Erik; Wille-Reece, Ulrike; Ockenhouse, Christian; Aderem, Alan; Zak, Daniel E.; et al. (Proceedings of the National Academy of Sciences - PNAS, 2017)
Keywords: Adaptive Immunity - drug effects; Adenoviridae; Adenoviridae - genetics; Adenoviridae - immunology; Antibodies, Protozoan - biosynthesis; B-Lymphocytes - drug effects; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; Biological Sciences; CD4-Positive T-Lymphocytes - drug effects; CD4-Positive T-Lymphocytes - immunology; CD4-Positive T-Lymphocytes - metabolism; Dendritic Cells - drug effects; Dendritic Cells - immunology; Dendritic Cells - metabolism; Gene Expression Profiling; Gene Expression Regulation; Genetic Vectors - chemistry; Genetic Vectors - immunology; Humans; Immunity (Disease); Immunity, Innate - drug effects; Immunization; Immunization, Secondary - methods; Immunogenicity, Vaccine; Killer Cells, Natural - drug effects; Killer Cells, Natural - immunology; Killer Cells, Natural - metabolism; Malaria; Malaria Vaccines - administration & dosage; Malaria, Falciparum - immunology; Malaria, Falciparum - parasitology; Malaria, Falciparum - prevention & control; Parasitic protozoa; Plasmodium falciparum; Plasmodium falciparum - immunology; Plasmodium falciparum - pathogenicity; Proteins; Protozoan Proteins - administration & dosage; Protozoan Proteins - genetics; Protozoan Proteins - immunology; Systematic biology; Systems analysis; Vaccination - methods; Vaccines; Vaccines, Synthetic - administration & dosage; Vector-borne diseases; systems biology; systems vaccinology; vaccine; immune; malaria