An Automated Deep Learning Model for the Cerebellum Segmentation from Fetal Brain Images

• Published in: BioMed research international Vol. 2022; no. 1; p. 8342767
• Main Authors: Sreelakshmy, R., Titus, Anita, Sasirekha, N., Logashanmugam, E., Begam, R. Benazir, Ramkumar, G., Raju, Raja
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2022; John Wiley & Sons, Inc
• Subjects: Abnormalities; Algorithms; Automation; Back propagation; Biomedical research; Brain; Brain research; Central nervous system; Cerebellum; Cerebellum - diagnostic imaging; Deep Learning; Female; Fetal brain; Fetus; Fetuses; Gestational age; Humans; Image processing; Image Processing, Computer-Assisted - methods; Image segmentation; Imaging techniques; Machine learning; Medical examination; Medical imaging; Methods; Metric space; Neural networks; Neuroimaging; Optimization techniques; Pregnancy; Semantics; Ultrasonic imaging; Ultrasonics in obstetrics; Ultrasonography; Ultrasonography, Prenatal; Wiener filtering; India
• ISSN: 2314-6133; 2314-6141; 2314-6141
• DOI: 10.1155/2022/8342767

Cerebellum measures taken from routinely obtained ultrasound (US) images have been frequently employed to determine gestational age and identify developing central nervous system’s anatomical abnormalities. Standardized cerebellar assessments from large-scale clinical datasets are required to investigate correlations between the growing cerebellum and postnatal neurodevelopmental results. These studies could uncover structural abnormalities that could be employed as indicators to forecast neurodevelopmental and growth consequences. To achieve this, higher-throughput, precise, and impartial measures must be used to replace the existing human, semiautomatic, and advanced algorithms, which seem to be time-consuming and inaccurate. In this article, we presented an innovative deep learning (DL) technique for automatic fetal cerebellum segmentation from 2-dimensional (2D) US brain images. We present ReU-Net, a semantic segmentation network tailored to the anatomy of the fetal cerebellum. Moreover, we use U-Net as a foundation models with the incorporation of residual blocks and Wiener filter over the last 2 layers to segregate the cerebellum (c) from the noisy US data. 590 images for training and 150 images for testing were taken; also, we employed a 5-fold cross-assessment method. Our ReU-Net scored 91%, 92%, 25.42, 98%, 92%, and 94% for Dice Score Coefficient (DSC), F1-score, Hausdorff Distance (HD), accuracy, recall, and precision, correspondingly. The suggested method outperforms the other U-Net predicated techniques by a quantitatively significant margin (p 0.001). Our presented approach can be used to allow high bandwidth imaging techniques in medical study fetal US images as well as biometric evaluation on a broader scale in fetal US images.