SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations - Bustion, Annamarie E; Nayak, Renuka R; Agrawal, Ayushi; Turnbaugh, Peter J; Pollard, Katherine S (eLife, 2023)
Keywords: Algorithms; Bacteria; Bacteria - metabolism; Biochemistry and Chemical Biology; Clostridium scindens; Computational and Systems Biology; Digestive system; Drug metabolism; enzyme prediction; Enzymes; Experimental methods; Food; Gastrointestinal Microbiome; Genes; Genomes; Gut microbiota; Humans; Intestinal microflora; Metabolism; Metabolites; Methotrexate; microbiome metabolism; Microbiomes; Microbiota; Proteins; Queries; Research methodology; computational biology; microbiome metabolism; systems biology; chemical biology; biochemistry; methotrexate; enzyme prediction; Clostridium scindens