How low can you go – Insight into the level of mutated protein required to cause pathogenic effects in hypertrophic cardiomyopathy

Saved in:
Bibliographic Details
Published inJournal of Molecular and Cellular Cardiology Plus (Online) Vol. 1; p. 100009
Main Author Gehmlich, Katja
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.09.2022
Elsevier
Online AccessGet full text
ISSN2772-9761
2772-9761
DOI10.1016/j.jmccpl.2022.100009

Cover

ArticleNumber 100009
Author Gehmlich, Katja
Author_xml – sequence: 1
  givenname: Katja
  orcidid: 0000-0003-4019-1844
  surname: Gehmlich
  fullname: Gehmlich, Katja
  email: k.gehmlich@bham.ac.uk
  organization: Institute of Cardiovascular Sciences, University of Birmingham, UK
BackLink https://www.ncbi.nlm.nih.gov/pubmed/39801718$$D View this record in MEDLINE/PubMed
BookMark eNqFkcFu1DAQhiNUREvpGyDkI5ddbCdxEgkhoQroSpW4wNmyJ-ONlyRObacoNw68AW_Ik-BtSoW41JLl0a9__pHne56djG7ELHvJ6JZRJt4ctocBYOq3nHKepHSaJ9kZryq-aSrBTv6pT7OLEA7JwRuWN5w9y07zpqasYvVZ9vPKfSd9uqBGsriZ7B35_eMX2Y3B7rtI7BgdiR2SHm-xJ86QYY4qYksm7yLakXi8ma1PQjKCmgOSScXO7XG0QNAYhBhSDOmWCX30buqSDsq31g2LO3qXF9lTo_qAF_fvefb144cvl1eb68-fdpfvrzdQVCJuKq2EbrDJqRYUmDIcqlrzpqm1Mo3ITQlGQy7SSCNQtQVlLaetYUwXecl4fp7t1tzWqYOcvB2UX6RTVt4Jzu-l8tFCj5IKAaXQUFYtK0xNNSjKTQW6pNgi1inr9ZqV9nAzY4hysAGw79WIbg4yZ2VR13V1N_bVvXXWA7YPg_9SSIZiNYB3IXg0DxZG5ZG3PMiVtzzylivv1PZubcO0s1uLXgawOAK2iQfE9Cn7WMDb_wKgtwmb6r_h8nj7Hx4ezA8
Cites_doi 10.1085/jgp.201812160
10.1056/NEJMra0902923
ContentType Journal Article
Copyright 2022 The Author
Copyright_xml – notice: 2022 The Author
DBID 6I.
AAFTH
AAYXX
CITATION
NPM
7X8
DOA
DOI 10.1016/j.jmccpl.2022.100009
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
PubMed
MEDLINE - Academic
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
PubMed
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
EISSN 2772-9761
ExternalDocumentID oai_doaj_org_article_066c56bc57d14f80bca02f7cb50edee8
39801718
10_1016_j_jmccpl_2022_100009
S2772976122000034
Genre Journal Article
GrantInformation_xml – fundername: Medical Research Council
  grantid: MR/V009540/1
– fundername: National Centre for the Replacement, Refinement and Reduction of Animals in Research
  grantid: NC/T001747/1
GroupedDBID .1-
.FO
0R~
AALRI
AAXUO
AAYWO
ACVFH
ADCNI
ADVLN
AEUPX
AEXQZ
AFJKZ
AFPUW
AFRHN
AIGII
AITUG
AJUYK
AKBMS
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
APXCP
EBS
FDB
GROUPED_DOAJ
M41
M~E
ROL
RPM
Z5R
6I.
AAFTH
AAYXX
CITATION
NPM
7X8
ID FETCH-LOGICAL-c476t-7ba6b9e930b60c1af2c78b2998baf963f5cfbc36fecf6ead401d20df11b435123
IEDL.DBID DOA
ISSN 2772-9761
IngestDate Wed Aug 27 01:27:29 EDT 2025
Thu Sep 04 23:49:28 EDT 2025
Mon Jul 21 05:56:20 EDT 2025
Thu Sep 11 00:19:48 EDT 2025
Fri Feb 23 02:39:51 EST 2024
Tue Aug 26 20:07:51 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Language English
License This is an open access article under the CC BY-NC-ND license.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c476t-7ba6b9e930b60c1af2c78b2998baf963f5cfbc36fecf6ead401d20df11b435123
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0003-4019-1844
OpenAccessLink https://doaj.org/article/066c56bc57d14f80bca02f7cb50edee8
PMID 39801718
PQID 3154888712
PQPubID 23479
ParticipantIDs doaj_primary_oai_doaj_org_article_066c56bc57d14f80bca02f7cb50edee8
proquest_miscellaneous_3154888712
pubmed_primary_39801718
crossref_primary_10_1016_j_jmccpl_2022_100009
elsevier_sciencedirect_doi_10_1016_j_jmccpl_2022_100009
elsevier_clinicalkey_doi_10_1016_j_jmccpl_2022_100009
PublicationCentury 2000
PublicationDate September 2022
2022-09-00
2022-Sep
20220901
2022-09-01
PublicationDateYYYYMMDD 2022-09-01
PublicationDate_xml – month: 09
  year: 2022
  text: September 2022
PublicationDecade 2020
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Journal of Molecular and Cellular Cardiology Plus (Online)
PublicationTitleAlternate J Mol Cell Cardiol Plus
PublicationYear 2022
Publisher Elsevier Ltd
Elsevier
Publisher_xml – name: Elsevier Ltd
– name: Elsevier
References Piroddi, Witjas-Paalberends, Ferrara, Ferrantini, Vitale, Scellini, Wijnker, Sequiera, Dooijes, Dos Remedios, Schlossarek, Leung, Messer, Ward, Biggeri, Tesi, Carrier, Redwood, Marston, van der Velden, Poggesi (bb0010) 2019; 151
Watkins, Ashrafian, Redwood (bb0005) 2011; 364
Sequeira (bb6005) 2022
Sequeira (10.1016/j.jmccpl.2022.100009_bb6005) 2022
Watkins (10.1016/j.jmccpl.2022.100009_bb0005) 2011; 364
Piroddi (10.1016/j.jmccpl.2022.100009_bb0010) 2019; 151
References_xml – year: 2022
  ident: bb6005
  article-title: JMCC Plus
– volume: 151
  start-page: 18
  year: 2019
  end-page: 29
  ident: bb0010
  article-title: The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM
  publication-title: J Gen Physiol
– volume: 364
  start-page: 1643
  year: 2011
  end-page: 1656
  ident: bb0005
  article-title: Inherited cardiomyopathies
  publication-title: N Engl J Med
– volume: 151
  start-page: 18
  issue: 1
  year: 2019
  ident: 10.1016/j.jmccpl.2022.100009_bb0010
  article-title: The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM
  publication-title: J Gen Physiol
  doi: 10.1085/jgp.201812160
– year: 2022
  ident: 10.1016/j.jmccpl.2022.100009_bb6005
– volume: 364
  start-page: 1643
  issue: 17
  year: 2011
  ident: 10.1016/j.jmccpl.2022.100009_bb0005
  article-title: Inherited cardiomyopathies
  publication-title: N Engl J Med
  doi: 10.1056/NEJMra0902923
SSID ssj0002913921
Score 2.1974514
SourceID doaj
proquest
pubmed
crossref
elsevier
SourceType Open Website
Aggregation Database
Index Database
Publisher
StartPage 100009
Title How low can you go – Insight into the level of mutated protein required to cause pathogenic effects in hypertrophic cardiomyopathy
URI https://www.clinicalkey.com/#!/content/1-s2.0-S2772976122000034
https://dx.doi.org/10.1016/j.jmccpl.2022.100009
https://www.ncbi.nlm.nih.gov/pubmed/39801718
https://www.proquest.com/docview/3154888712
https://doaj.org/article/066c56bc57d14f80bca02f7cb50edee8
Volume 1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2772-9761
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0002913921
  issn: 2772-9761
  databaseCode: DOA
  dateStart: 20220101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 2772-9761
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0002913921
  issn: 2772-9761
  databaseCode: M~E
  dateStart: 20220101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
– providerCode: PRVAQN
  databaseName: PubMed Central
  customDbUrl:
  eissn: 2772-9761
  dateEnd: 99991231
  omitProxy: true
  ssIdentifier: ssj0002913921
  issn: 2772-9761
  databaseCode: RPM
  dateStart: 20220101
  isFulltext: true
  titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/
  providerName: National Library of Medicine
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV07j9QwELbQVTQIxGvhOBmJNpB3nBIQpwUJKk66zvJMbG5Pt_FqNxHajoJ_wD_klzBjJ6u7Ah0FRRrLj9gz9veNPR4L8aooVdllFpIaVZWUSOaOQTBJW6AluDfQAF9O_vylXp6Vn86r82tPfbFPWAwPHAfuDUEiVjVg1XRZ6VQKaNLcNQhVajtrwzVfgrFrxhSvwTlHu8yz-a5ccOi6XCNu-LQhz1-HXe32BhaFkP03IOlvlDNAz-l9cW_ijPJt_NcH4o7tH4qfS_9dXtFHYyP3fpTfvPz945f82O_Y3parfvCS2J28Yrcg6Z1cj0wsOxlCM6x6ubXsBUwJlBHNuLOSnyf2pFErlJOfB1UjL8hU3Q5bv7mgdAz-q-u957z7R-Ls9MPX98tkelIhwbKph6QBU0Nr2yKFOsXMuBwbBQRJCoyjuegqdIBFTU24mpSMrK8uTzuXZUC8ilDusTjqfW-fCpmC6mxjCzCqZSNRGaqzKG1LBh-xLliIZB5cvYmRM_TsUnapozA0C0NHYSzEO5bAIS_HvQ4JpA160gZ9mzYsRDXLT89XS2kxpIpWtzTeHMpN1CNSin8o-XJWE00zk49bTG_9uNMFW4O0hmf5QjyJ-nPoXNEqDlSknv2PTj8Xd_mHoufbsTgatqN9QVRpgJMwK07CHtYfv3UXNQ
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=How+low+can+you+go+%E2%80%93+Insight+into+the+level+of+mutated+protein+required+to+cause+pathogenic+effects+in+hypertrophic+cardiomyopathy&rft.jtitle=Journal+of+Molecular+and+Cellular+Cardiology+Plus+%28Online%29&rft.au=Gehmlich%2C+Katja&rft.date=2022-09-01&rft.pub=Elsevier+Ltd&rft.issn=2772-9761&rft.eissn=2772-9761&rft.volume=1&rft_id=info:doi/10.1016%2Fj.jmccpl.2022.100009&rft.externalDocID=S2772976122000034
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2772-9761&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2772-9761&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2772-9761&client=summon