Epithelial−mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer - Jeong, Hyein; Koh, Jaemoon; Kim, Sehui; Song, Seung Geun; Lee, Soo Hyun; Jeon, Youngjoo; Lee, Chul-Hwan; Keam, Bhumsuk; Lee, Se-Hoon; Chung, Doo Hyun; Jeon, Yoon Kyung (British journal of cancer, 2024)
Keywords: 631/67/327; 692/4028/67/1059/2325; 692/4028/67/1612/1350; 692/53/2423; Animals; B7-H1 Antigen - genetics; B7-H1 Antigen - metabolism; Biomedical and Life Sciences; Biomedicine; Cancer Research; Carcinoma, Non-Small-Cell Lung - drug therapy; Carcinoma, Non-Small-Cell Lung - genetics; Carcinoma, Non-Small-Cell Lung - immunology; Carcinoma, Non-Small-Cell Lung - metabolism; Carcinoma, Non-Small-Cell Lung - pathology; Cell Line, Tumor; Cytotoxicity; Drug Resistance; Epidemiology; Epithelial-Mesenchymal Transition; Female; Humans; Immune checkpoint inhibitors; Immune Checkpoint Inhibitors - pharmacology; Immune Checkpoint Inhibitors - therapeutic use; Infiltration; Lung cancer; Lung Neoplasms - drug therapy; Lung Neoplasms - genetics; Lung Neoplasms - immunology; Lung Neoplasms - metabolism; Lung Neoplasms - pathology; Lymphocytes T; Macrophages; MAP kinase; Metastases; Mice; Mice, Nude; Molecular Medicine; Non-small cell lung carcinoma; Oncology; PD-L1 protein; Phenotypes; Protein phosphatase; Signal Transduction; Small cell lung carcinoma; Transforming Growth Factor beta - metabolism; Tumors