Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome

Patients with decompensated heart failure and cardiorenal syndrome were randomly assigned to ultrafiltration or diuretic therapy. Ultrafiltration was inferior to diuretics with respect to the primary end point, a bivariate measure of change in creatinine and body weight. The acute cardiorenal syndro...

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Published inThe New England journal of medicine Vol. 367; no. 24; pp. 2296 - 2304
Main Authors Bart, Bradley A, Goldsmith, Steven R, Lee, Kerry L, Givertz, Michael M, O'Connor, Christopher M, Bull, David A, Redfield, Margaret M, Deswal, Anita, Rouleau, Jean L, LeWinter, Martin M, Ofili, Elizabeth O, Stevenson, Lynne W, Semigran, Marc J, Felker, G. Michael, Chen, Horng H, Hernandez, Adrian F, Anstrom, Kevin J, McNulty, Steven E, Velazquez, Eric J, Ibarra, Jenny C, Mascette, Alice M, Braunwald, Eugene
Format Journal Article
LanguageEnglish
Published Waltham, MA Massachusetts Medical Society 13.12.2012
Subjects
Online AccessGet full text
ISSN0028-4793
1533-4406
1533-4406
DOI10.1056/NEJMoa1210357

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Abstract Patients with decompensated heart failure and cardiorenal syndrome were randomly assigned to ultrafiltration or diuretic therapy. Ultrafiltration was inferior to diuretics with respect to the primary end point, a bivariate measure of change in creatinine and body weight. The acute cardiorenal syndrome (type 1) is defined as worsening renal function in patients with acute decompensated heart failure. 1 It occurs in 25 to 33% of patients with acute decompensated heart failure and is associated with poor outcomes. 1 , 2 Multiple processes contribute to the development of the acute cardiorenal syndrome, including extrarenal hemodynamic changes, neurohormonal activation, intrarenal microvascular and cellular dysregulation, and oxidative stress. 1 In some cases, intravenous diuretics, which are often administered in patients with acute decompensated heart failure, 3 may directly contribute to worsening renal function. 1 , 4 , 5 The use of diuretics to treat persistent congestion after the onset . . .
AbstractList Patients with decompensated heart failure and cardiorenal syndrome were randomly assigned to ultrafiltration or diuretic therapy. Ultrafiltration was inferior to diuretics with respect to the primary end point, a bivariate measure of change in creatinine and body weight. The acute cardiorenal syndrome (type 1) is defined as worsening renal function in patients with acute decompensated heart failure. 1 It occurs in 25 to 33% of patients with acute decompensated heart failure and is associated with poor outcomes. 1 , 2 Multiple processes contribute to the development of the acute cardiorenal syndrome, including extrarenal hemodynamic changes, neurohormonal activation, intrarenal microvascular and cellular dysregulation, and oxidative stress. 1 In some cases, intravenous diuretics, which are often administered in patients with acute decompensated heart failure, 3 may directly contribute to worsening renal function. 1 , 4 , 5 The use of diuretics to treat persistent congestion after the onset . . .
Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function. We randomly assigned a total of 188 patients with acute decompensated heart failure, worsened renal function, and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafiltration (94 patients). The primary end point was the bivariate change from baseline in the serum creatinine level and body weight, as assessed 96 hours after random assignment. Patients were followed for 60 days. Ultrafiltration was inferior to pharmacologic therapy with respect to the bivariate end point of the change in the serum creatinine level and body weight 96 hours after enrollment (P=0.003), owing primarily to an increase in the creatinine level in the ultrafiltration group. At 96 hours, the mean change in the creatinine level was -0.04±0.53 mg per deciliter (-3.5±46.9 μmol per liter) in the pharmacologic-therapy group, as compared with +0.23±0.70 mg per deciliter (20.3±61.9 μmol per liter) in the ultrafiltration group (P=0.003). There was no significant difference in weight loss 96 hours after enrollment between patients in the pharmacologic-therapy group and those in the ultrafiltration group (a loss of 5.5±5.1 kg [12.1±11.3 lb] and 5.7±3.9 kg [12.6±8.5 lb], respectively; P=0.58). A higher percentage of patients in the ultrafiltration group than in the pharmacologic-therapy group had a serious adverse event (72% vs. 57%, P=0.03). In a randomized trial involving patients hospitalized for acute decompensated heart failure, worsened renal function, and persistent congestion, the use of a stepped pharmacologic-therapy algorithm was superior to a strategy of ultrafiltration for the preservation of renal function at 96 hours, with a similar amount of weight loss with the two approaches. Ultrafiltration was associated with a higher rate of adverse events. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00608491.).
Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function.BACKGROUNDUltrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function.We randomly assigned a total of 188 patients with acute decompensated heart failure, worsened renal function, and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafiltration (94 patients). The primary end point was the bivariate change from baseline in the serum creatinine level and body weight, as assessed 96 hours after random assignment. Patients were followed for 60 days.METHODSWe randomly assigned a total of 188 patients with acute decompensated heart failure, worsened renal function, and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafiltration (94 patients). The primary end point was the bivariate change from baseline in the serum creatinine level and body weight, as assessed 96 hours after random assignment. Patients were followed for 60 days.Ultrafiltration was inferior to pharmacologic therapy with respect to the bivariate end point of the change in the serum creatinine level and body weight 96 hours after enrollment (P=0.003), owing primarily to an increase in the creatinine level in the ultrafiltration group. At 96 hours, the mean change in the creatinine level was -0.04±0.53 mg per deciliter (-3.5±46.9 μmol per liter) in the pharmacologic-therapy group, as compared with +0.23±0.70 mg per deciliter (20.3±61.9 μmol per liter) in the ultrafiltration group (P=0.003). There was no significant difference in weight loss 96 hours after enrollment between patients in the pharmacologic-therapy group and those in the ultrafiltration group (a loss of 5.5±5.1 kg [12.1±11.3 lb] and 5.7±3.9 kg [12.6±8.5 lb], respectively; P=0.58). A higher percentage of patients in the ultrafiltration group than in the pharmacologic-therapy group had a serious adverse event (72% vs. 57%, P=0.03).RESULTSUltrafiltration was inferior to pharmacologic therapy with respect to the bivariate end point of the change in the serum creatinine level and body weight 96 hours after enrollment (P=0.003), owing primarily to an increase in the creatinine level in the ultrafiltration group. At 96 hours, the mean change in the creatinine level was -0.04±0.53 mg per deciliter (-3.5±46.9 μmol per liter) in the pharmacologic-therapy group, as compared with +0.23±0.70 mg per deciliter (20.3±61.9 μmol per liter) in the ultrafiltration group (P=0.003). There was no significant difference in weight loss 96 hours after enrollment between patients in the pharmacologic-therapy group and those in the ultrafiltration group (a loss of 5.5±5.1 kg [12.1±11.3 lb] and 5.7±3.9 kg [12.6±8.5 lb], respectively; P=0.58). A higher percentage of patients in the ultrafiltration group than in the pharmacologic-therapy group had a serious adverse event (72% vs. 57%, P=0.03).In a randomized trial involving patients hospitalized for acute decompensated heart failure, worsened renal function, and persistent congestion, the use of a stepped pharmacologic-therapy algorithm was superior to a strategy of ultrafiltration for the preservation of renal function at 96 hours, with a similar amount of weight loss with the two approaches. Ultrafiltration was associated with a higher rate of adverse events. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00608491.).CONCLUSIONSIn a randomized trial involving patients hospitalized for acute decompensated heart failure, worsened renal function, and persistent congestion, the use of a stepped pharmacologic-therapy algorithm was superior to a strategy of ultrafiltration for the preservation of renal function at 96 hours, with a similar amount of weight loss with the two approaches. Ultrafiltration was associated with a higher rate of adverse events. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00608491.).
Background Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the efficacy and safety of ultrafiltration in patients with acute decompensated heart failure complicated by persistent congestion and worsened renal function. Methods We randomly assigned a total of 188 patients with acute decompensated heart failure, worsened renal function, and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafiltration (94 patients). The primary end point was the bivariate change from baseline in the serum creatinine level and body weight, as assessed 96 hours after random assignment. Patients were followed for 60 days. Results Ultrafiltration was inferior to pharmacologic therapy with respect to the bivariate end point of the change in the serum creatinine level and body weight 96 hours after enrollment (P=0.003), owing primarily to an increase in the creatinine level in the ultrafiltration group. At 96 hours, the mean change in the creatinine level was -0.04±0.53 mg per deciliter (-3.5±46.9 μmol per liter) in the pharmacologic-therapy group, as compared with +0.23±0.70 mg per deciliter (20.3±61.9 μmol per liter) in the ultrafiltration group (P=0.003). There was no significant difference in weight loss 96 hours after enrollment between patients in the pharmacologic-therapy group and those in the ultrafiltration group (a loss of 5.5±5.1 kg [12.1±11.3 lb] and 5.7±3.9 kg [12.6±8.5 lb], respectively; P=0.58). A higher percentage of patients in the ultrafiltration group than in the pharmacologic-therapy group had a serious adverse event (72% vs. 57%, P=0.03). Conclusions In a randomized trial involving patients hospitalized for acute decompensated heart failure, worsened renal function, and persistent congestion, the use of a stepped pharmacologic-therapy algorithm was superior to a strategy of ultrafiltration for the preservation of renal function at 96 hours, with a similar amount of weight loss with the two approaches. Ultrafiltration was associated with a higher rate of adverse events. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00608491.)
Author Deswal, Anita
Stevenson, Lynne W
Ibarra, Jenny C
LeWinter, Martin M
Bart, Bradley A
Chen, Horng H
O'Connor, Christopher M
Semigran, Marc J
Lee, Kerry L
Mascette, Alice M
Ofili, Elizabeth O
Velazquez, Eric J
Felker, G. Michael
Goldsmith, Steven R
Hernandez, Adrian F
Anstrom, Kevin J
Redfield, Margaret M
Givertz, Michael M
Rouleau, Jean L
McNulty, Steven E
Bull, David A
Braunwald, Eugene
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  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
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  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
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  givenname: Elizabeth O
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  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
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  givenname: Lynne W
  surname: Stevenson
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  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
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  givenname: Marc J
  surname: Semigran
  fullname: Semigran, Marc J
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 14
  givenname: G. Michael
  surname: Felker
  fullname: Felker, G. Michael
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 15
  givenname: Horng H
  surname: Chen
  fullname: Chen, Horng H
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 16
  givenname: Adrian F
  surname: Hernandez
  fullname: Hernandez, Adrian F
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 17
  givenname: Kevin J
  surname: Anstrom
  fullname: Anstrom, Kevin J
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 18
  givenname: Steven E
  surname: McNulty
  fullname: McNulty, Steven E
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 19
  givenname: Eric J
  surname: Velazquez
  fullname: Velazquez, Eric J
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 20
  givenname: Jenny C
  surname: Ibarra
  fullname: Ibarra, Jenny C
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 21
  givenname: Alice M
  surname: Mascette
  fullname: Mascette, Alice M
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
– sequence: 22
  givenname: Eugene
  surname: Braunwald
  fullname: Braunwald, Eugene
  organization: From the Hennepin County Medical Center, Minneapolis (B.A.B., S.R.G.) and Mayo Clinic, Rochester (M.M.R., H.H.C.) — both in Minnesota; Duke Clinical Research Institute (K.L.L., A.F.H., K.J.A., S.E.M., E.J.V., J.C.I.) and Duke University Medical Center and Duke Heart Center (C.M.O., G.M.F.) — both in Durham, NC; Brigham and Women's Hospital (M.M.G., L.W.S., E.B.) and Massachusetts General Hospital (M.J.S.) — both in Boston; University of Utah, Salt Lake City (D.A.B.); Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston (A.D.); University of Montreal and Montreal Heart Institute, Montreal (J.L.R.); University of Vermont, Burlington (M.M.L.); Morehouse School of Medicine, Atlanta (E.O.O.); and the National Heart, Lung, and Blood Institute, Bethesda, MD (A.M.M.)
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26727121$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/23131078$$D View this record in MEDLINE/PubMed
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CODEN NEJMAG
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Cites_doi 10.1016/j.jacc.2003.07.031
10.1016/j.cardfail.2006.02.007
10.1053/j.ajkd.2011.07.023
10.1056/NEJMoa0912613
10.1016/j.cardfail.2011.12.009
10.1016/j.ahj.2003.08.012
10.1016/j.jacc.2012.01.077
10.1161/CIRCULATIONAHA.109.192065
10.1056/NEJMoa1005419
10.1016/S0735-1097(01)01479-6
10.2307/2281868
10.1016/j.cardfail.2008.03.002
10.1214/aoms/1177732979
10.1056/NEJMoa1100171
10.1161/CIRCHEARTFAILURE.111.963413
10.1016/j.jacc.2006.07.073
10.1378/chest.116.5.1208
10.1016/j.jacc.2005.05.098
10.1016/j.jacc.2011.10.910
10.1161/CIRCHEARTFAILURE.109.863381
10.1161/CIRCULATIONAHA.109.933275
ContentType Journal Article
Contributor Lee, K
Redfield, M
Sheppard, R
Mackendanz, S
Parillo, J
Lipinski, P
Velazquez, E
Bart, B
Cai, J
Deswal, A
Kfoury, A
Bull, D
Stehlik, J
Milbrandt, S
Morrissette, J
Greenberg, B
Tracy, R
Bozkurt, B
Chadwick, L
Virmani, R
Desvigne-Nickens, P
Mascette, A
Abraham, W
St Laurent, K
Ofili, E
Felker, M
Rosenberg, R
Hegeman, J
Scanlon, J
Johnson, M
Penn, M
Anstrom, K
Tuinei, J
Rose, E
Anello, S
Cocca-Spofford, D
Rouleau, J
Ibarra, J
Johnson, J
Fleurent, J
Geyen, K
Fleck, D
Altmus, D
Ducharme, A
Hanovich, G
Chee, A
Ryan, J
Cornell, E
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Keywords Heart failure
Medicine
Cardiovascular disease
Ultrafiltration
Heart disease
Syndrome
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References Testani, JM, Chen, J, McCauley, BD, Kimmel, SE, Shannon, RP (r021) 2010; 122
Costanzo, MR, Guglin, ME, Saltzberg, MT (r010) 2007; 49
Bart, BA, Boyle, A, Bank, AJ (r015) 2005; 46
Butler, J, Forman, DE, Abraham, WT (r017) 2004; 147
Forman, DE, Butler, J, Wang, Y (r018) 2004; 43
Grant, S, Aitchison, T, Henderson, E (r009) 1999; 116
Felker, GM, Lee, KL, Bull, DA (r020) 2011; 364
r011
Bart, BA, Walsh, MM, Blake, D, Goldsmith, SR (r016) 2008; 14
Marenzi, G, Lauri, G, Grazi, M, Assanelli, E, Campodonico, J, Agostoni, P (r014) 2001; 38
Bart, BA, Goldsmith, SR, Lee, KL (r007) 2012; 18
r013
Hunt, SA, Abraham, WT, Chin, MH (r003) 2009; 119
Metra, M, Davison, B, Bettari, L (r002) 2012; 5
Hotelling, H (r008) 1931; 2
Felker, GM, Mentz, RJ (r004) 2012; 59
Bart, BA (r006) 2009; 2
Kaplan, EL, Meier, P (r012) 1958; 53
Ronco, C, Cicoira, M, McCullough, PA (r001) 2012; 60
O'Connor, CM, Starling, RC, Hernandez, AF (r022) 2011; 365
Owan, TE, Hodge, DO, Herges, RM, Jacobsen, SJ, Roger, VL, Redfield, MM (r019) 2006; 12
Massie, BM, O'Connor, CM, Metra, M (r023) 2010; 363
Freda, BJ, Slawsky, M, Mallidi, J, Braden, GL (r005) 2011; 58
r020
r010
r021
r022
r001
r012
r023
r006
r017
r007
r018
r008
r019
r009
r002
r003
r014
r004
r015
r005
r016
22014726 - Am J Kidney Dis. 2011 Dec;58(6):1005-17
10559077 - Chest. 1999 Nov;116(5):1208-17
14760333 - Am Heart J. 2004 Feb;147(2):331-8
20925544 - N Engl J Med. 2010 Oct 7;363(15):1419-28
16325039 - J Am Coll Cardiol. 2005 Dec 6;46(11):2043-6
22676934 - J Am Coll Cardiol. 2012 Jun 12;59(24):2145-53
22385937 - J Card Fail. 2012 Mar;18(3):176-82
23131079 - N Engl J Med. 2012 Dec 13;367(24):2351-2
22840531 - J Am Coll Cardiol. 2012 Sep 18;60(12):1031-42
23514297 - N Engl J Med. 2013 Mar 21;368(12):1157-8
23165076 - Nat Rev Cardiol. 2013 Jan;10(1):2
22167320 - Circ Heart Fail. 2012 Jan;5(1):54-62
14715185 - J Am Coll Cardiol. 2004 Jan 7;43(1):61-7
21366472 - N Engl J Med. 2011 Mar 3;364(9):797-805
23514296 - N Engl J Med. 2013 Mar 21;368(12):1157
23548557 - Am J Kidney Dis. 2013 Sep;62(3):453-6
23514298 - N Engl J Med. 2013 Mar 21;368(12):1158
11583865 - J Am Coll Cardiol. 2001 Oct;38(4):963-8
19324966 - Circulation. 2009 Apr 14;119(14):e391-479
21732835 - N Engl J Med. 2011 Jul 7;365(1):32-43
20606118 - Circulation. 2010 Jul 20;122(3):265-72
18672202 - J Card Fail. 2008 Aug;14(6):531-2; author reply 532-3
23514295 - N Engl J Med. 2013 Mar 21;368(12):1159-60
16679257 - J Card Fail. 2006 May;12(4):257-62
23514299 - N Engl J Med. 2013 Mar 21;368(12):1158-9
23165301 - Nat Rev Nephrol. 2013 Jan;9(1):2
19808381 - Circ Heart Fail. 2009 Sep;2(5):499-504
17291932 - J Am Coll Cardiol. 2007 Feb 13;49(6):675-83
References_xml – volume: 46
  start-page: 2043
  year: 2005
  end-page: 2046
  ident: r015
  article-title: Ultrafiltration versus usual care for hospitalized patients with heart failure: the Relief for Acutely Fluid-Overloaded Patients with Decompensated Congestive Heart Failure (RAPID-CHF) trial.
  publication-title: J Am Coll Cardiol
– volume: 12
  start-page: 257
  year: 2006
  end-page: 262
  ident: r019
  article-title: Secular trends in renal dysfunction and outcomes in hospitalized heart failure patients.
  publication-title: J Card Fail
– volume: 363
  start-page: 1419
  year: 2010
  end-page: 1428
  ident: r023
  article-title: Rolofylline, an adenosine A -receptor antagonist, in acute heart failure.
  publication-title: N Engl J Med
– volume: 2
  start-page: 499
  year: 2009
  end-page: 504
  ident: r006
  article-title: Treatment of congestion in congestive heart failure: ultrafiltration is the only rational initial treatment of volume overload in decompensated heart failure.
  publication-title: Circ Heart Fail
– volume: 116
  start-page: 1208
  year: 1999
  end-page: 1217
  ident: r009
  article-title: A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
  publication-title: Chest
– volume: 122
  start-page: 265
  year: 2010
  end-page: 272
  ident: r021
  article-title: Potential effects of aggressive decongestion during the treatment of decompensated heart failure on renal function and survival.
  publication-title: Circulation
– volume: 119
  start-page: e391
  year: 2009
  end-page: e479
  ident: r003
  article-title: 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation.
  publication-title: Circulation ;[Erratum, Circulation 2010;121(12)e258.]
– volume: 38
  start-page: 963
  year: 2001
  end-page: 968
  ident: r014
  article-title: Circulatory response to fluid overload removal by extracorporeal ultrafiltration in refractory congestive heart failure.
  publication-title: J Am Coll Cardiol
– ident: r011
  article-title: Multivariate linear regression models. In: Johnson RA, Wichern DW. Applied multivariate statistical analysis. 6th ed. Upper Saddle River, NJ: Pearson Prentice Hall, 2007:331-3.
– ident: r013
  article-title: Cox DR. Regression models and life-tables. J R Stat Soc, B 1972;34:187-220.
– volume: 18
  start-page: 176
  year: 2012
  end-page: 182
  ident: r007
  article-title: Cardiorenal rescue study in acute decompensated heart failure: rationale and design of CARRESS-HF, for the Heart Failure Clinical Research Network.
  publication-title: J Card Fail
– volume: 58
  start-page: 1005
  year: 2011
  end-page: 1017
  ident: r005
  article-title: Decongestive treatment of acute decompensated heart failure: cardiorenal implications of ultrafiltration and diuretics.
  publication-title: Am J Kidney Dis
– volume: 53
  start-page: 457
  year: 1958
  end-page: 481
  ident: r012
  article-title: Nonparametric estimation from incomplete observations.
  publication-title: J Am Stat Assoc
– volume: 49
  start-page: 675
  year: 2007
  end-page: 683
  ident: r010
  article-title: Ultrafiltration versus intravenous diuretics for patients hospitalized for acute decompensated heart failure.
  publication-title: J Am Coll Cardiol ;[Erratum, J Am Coll Cardiol 2007;49:1136.]
– volume: 59
  start-page: 2145
  year: 2012
  end-page: 2153
  ident: r004
  article-title: Diuretics and ultrafiltration in acute decompensated heart failure.
  publication-title: J Am Coll Cardiol
– volume: 364
  start-page: 797
  year: 2011
  end-page: 805
  ident: r020
  article-title: Diuretic strategies in patients with acute decompensated heart failure.
  publication-title: N Engl J Med
– volume: 60
  start-page: 1031
  year: 2012
  end-page: 1042
  ident: r001
  article-title: Cardiorenal syndrome type 1: pathophysiological crosstalk leading to combined heart and kidney dysfunction in the setting of acutely decompensated heart failure.
  publication-title: J Am Coll Cardiol
– volume: 365
  start-page: 32
  year: 2011
  end-page: 43
  ident: r022
  article-title: Effect of nesiritide in patients with acute decompensated heart failure.
  publication-title: N Engl J Med ;[Erratum, N Engl J Med 2011;365:773.]
– volume: 2
  start-page: 360
  year: 1931
  end-page: 378
  ident: r008
  article-title: The generalization of Student's ratio.
  publication-title: Ann Math Stat
– volume: 14
  start-page: 531
  year: 2008
  end-page: 533
  ident: r016
  article-title: Ultrafiltration for cardiorenal syndrome.
  publication-title: J Card Fail
– volume: 147
  start-page: 331
  year: 2004
  end-page: 338
  ident: r017
  article-title: Relationship between heart failure treatment and development of worsening renal function among hospitalized patients.
  publication-title: Am Heart J
– volume: 5
  start-page: 54
  year: 2012
  end-page: 62
  ident: r002
  article-title: Is worsening renal function an ominous prognostic sign in patients with acute heart failure? The role of congestion and its interaction with renal function.
  publication-title: Circ Heart Fail
– volume: 43
  start-page: 61
  year: 2004
  end-page: 67
  ident: r018
  article-title: Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure.
  publication-title: J Am Coll Cardiol
– ident: r018
  doi: 10.1016/j.jacc.2003.07.031
– ident: r019
  doi: 10.1016/j.cardfail.2006.02.007
– ident: r005
  doi: 10.1053/j.ajkd.2011.07.023
– ident: r023
  doi: 10.1056/NEJMoa0912613
– ident: r007
  doi: 10.1016/j.cardfail.2011.12.009
– ident: r017
  doi: 10.1016/j.ahj.2003.08.012
– ident: r001
  doi: 10.1016/j.jacc.2012.01.077
– ident: r003
  doi: 10.1161/CIRCULATIONAHA.109.192065
– ident: r020
  doi: 10.1056/NEJMoa1005419
– ident: r014
  doi: 10.1016/S0735-1097(01)01479-6
– ident: r012
  doi: 10.2307/2281868
– ident: r016
  doi: 10.1016/j.cardfail.2008.03.002
– ident: r008
  doi: 10.1214/aoms/1177732979
– ident: r022
  doi: 10.1056/NEJMoa1100171
– ident: r002
  doi: 10.1161/CIRCHEARTFAILURE.111.963413
– ident: r010
  doi: 10.1016/j.jacc.2006.07.073
– ident: r009
  doi: 10.1378/chest.116.5.1208
– ident: r015
  doi: 10.1016/j.jacc.2005.05.098
– ident: r004
  doi: 10.1016/j.jacc.2011.10.910
– ident: r006
  doi: 10.1161/CIRCHEARTFAILURE.109.863381
– ident: r021
  doi: 10.1161/CIRCULATIONAHA.109.933275
– reference: 16679257 - J Card Fail. 2006 May;12(4):257-62
– reference: 23514296 - N Engl J Med. 2013 Mar 21;368(12):1157
– reference: 14715185 - J Am Coll Cardiol. 2004 Jan 7;43(1):61-7
– reference: 22167320 - Circ Heart Fail. 2012 Jan;5(1):54-62
– reference: 18672202 - J Card Fail. 2008 Aug;14(6):531-2; author reply 532-3
– reference: 22385937 - J Card Fail. 2012 Mar;18(3):176-82
– reference: 22840531 - J Am Coll Cardiol. 2012 Sep 18;60(12):1031-42
– reference: 14760333 - Am Heart J. 2004 Feb;147(2):331-8
– reference: 11583865 - J Am Coll Cardiol. 2001 Oct;38(4):963-8
– reference: 20925544 - N Engl J Med. 2010 Oct 7;363(15):1419-28
– reference: 23131079 - N Engl J Med. 2012 Dec 13;367(24):2351-2
– reference: 16325039 - J Am Coll Cardiol. 2005 Dec 6;46(11):2043-6
– reference: 23514299 - N Engl J Med. 2013 Mar 21;368(12):1158-9
– reference: 21366472 - N Engl J Med. 2011 Mar 3;364(9):797-805
– reference: 23548557 - Am J Kidney Dis. 2013 Sep;62(3):453-6
– reference: 23514298 - N Engl J Med. 2013 Mar 21;368(12):1158
– reference: 20606118 - Circulation. 2010 Jul 20;122(3):265-72
– reference: 23514297 - N Engl J Med. 2013 Mar 21;368(12):1157-8
– reference: 19324966 - Circulation. 2009 Apr 14;119(14):e391-479
– reference: 23165301 - Nat Rev Nephrol. 2013 Jan;9(1):2
– reference: 19808381 - Circ Heart Fail. 2009 Sep;2(5):499-504
– reference: 17291932 - J Am Coll Cardiol. 2007 Feb 13;49(6):675-83
– reference: 22676934 - J Am Coll Cardiol. 2012 Jun 12;59(24):2145-53
– reference: 10559077 - Chest. 1999 Nov;116(5):1208-17
– reference: 21732835 - N Engl J Med. 2011 Jul 7;365(1):32-43
– reference: 22014726 - Am J Kidney Dis. 2011 Dec;58(6):1005-17
– reference: 23514295 - N Engl J Med. 2013 Mar 21;368(12):1159-60
– reference: 23165076 - Nat Rev Cardiol. 2013 Jan;10(1):2
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Snippet Patients with decompensated heart failure and cardiorenal syndrome were randomly assigned to ultrafiltration or diuretic therapy. Ultrafiltration was inferior...
Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known about the...
Background Ultrafiltration is an alternative strategy to diuretic therapy for the treatment of patients with acute decompensated heart failure. Little is known...
SourceID pubmedcentral
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pubmed
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SourceType Open Access Repository
Aggregation Database
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Publisher
StartPage 2296
SubjectTerms Aged
Algorithms
Biological and medical sciences
Cardio-Renal Syndrome - etiology
Cardio-Renal Syndrome - therapy
Cardiology. Vascular system
Creatinine - blood
Diuretics - adverse effects
Diuretics - therapeutic use
Drug therapy
Female
General aspects
Heart
Heart failure
Heart Failure - complications
Heart Failure - drug therapy
Heart Failure - mortality
Heart Failure - therapy
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Humans
Infusions, Intravenous
Male
Medical sciences
Middle Aged
Ultrafiltration - adverse effects
Weight Loss - drug effects
Title Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome
URI https://nejm.org/doi/full/10.1056/NEJMoa1210357
https://www.ncbi.nlm.nih.gov/pubmed/23131078
https://www.proquest.com/docview/1239051716
https://www.proquest.com/docview/1239055786
https://pubmed.ncbi.nlm.nih.gov/PMC3690472
Volume 367
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