A coarse-grained NADH redox model enables inference of subcellular metabolic fluxes from fluorescence lifetime imaging - Yang, Xingbo; Ha, Gloria; Needleman, Daniel J (eLife, 2021)
Keywords: Accuracy; Animals; Biochemistry; Biochemistry and Chemical Biology; Cell culture; coarse-grained model; Developmental biology; Electron transport chain; Energy; Enzymes; FLIM; Fluorescence; Homeostasis; Infertility; Lifetime; Machine learning; Mass spectrometry; metabolic flux; Metabolism; Metabolites; Mice; Microscopy; Microscopy, Fluorescence; Mitochondria; Mitochondria - metabolism; NAD - metabolism; NADH; Oocytes; Optical Imaging; Oxidation-Reduction; Oxygen consumption; Phosphorylation; Physics of Living Systems; Scientific imaging; Tissue culture; mouse; NADH; chemical biology; metabolic flux; oocytes; mitochondria; biochemistry; coarse-grained model; FLIM; human; physics of living systems