The Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Subjects With Type 2 Diabetes Mellitus - Sahasrabudhe, V.; Terra, S. G.; Hickman, A.; Saur, D.; Shi, H.; O'Gorman, M.; Zhou, Z.; Cutler, D. L. (Journal of clinical pharmacology, 2017)
Keywords: Aged; Blood Glucose - drug effects; Bridged Bicyclo Compounds, Heterocyclic - therapeutic use; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; ertugliflozin; Female; Glomerular Filtration Rate - physiology; Glucose - metabolism; Glucosides - metabolism; Humans; Hypoglycemic Agents - therapeutic use; Kidney - metabolism; Male; Middle Aged; renal impairment; Renal Insufficiency - metabolism; Sodium-Glucose Transporter 2 - metabolism; sodium‐glucose cotransporter 2; type 2 diabetes mellitus; type 2 diabetes mellitus; ertugliflozin; sodium-glucose cotransporter 2; renal impairment