Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential - Giner-Calabuig, Mar; De Leon, Seila; Wang, Julian; Fehlmann, Tara D.; Ukaegbu, Chinedu; Gibson, Joanna; Alustiza-Fernandez, Miren; Pico, Maria-Dolores; Alenda, Cristina; Herraiz, Maite; Carrillo-Palau, Marta; Salces, Inmaculada; et al. (British journal of cancer, 2022)
Keywords: 631/67/1504/1885/1393; 692/4028/67/69; Biomedical and Life Sciences; Biomedicine; Brain Neoplasms; Cancer Research; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis - genetics; DNA Mismatch Repair - genetics; Drug Resistance; Epidemiology; Genetic disorders; Histocompatibility antigen HLA; Humans; Immunogenicity; Microsatellite Instability; Mismatch repair; Mismatch Repair Endonuclease PMS2 - genetics; MLH1 protein; Molecular Medicine; MSH2 protein; MSH6 protein; Mutation; MutL Protein Homolog 1 - genetics; Neoantigens; Neoplastic Syndromes, Hereditary; Next-generation sequencing; Oncology; Phenotypes; Pms2 protein; Precision medicine; Tumors