Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence - Hanson, Robert L.; Van Hout, Cristopher V.; Hsueh, Wen-Chi; Shuldiner, Alan R.; Kobes, Sayuko; Sinha, Madhumita; Baier, Leslie J.; Knowler, William C. (Diabetologia, 2020)
Keywords: African Americans; Blood Glucose - metabolism; C-Peptide - metabolism; Cross-Sectional Studies; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Fasting; Gene frequency; Genetic analysis; Genetic distance; Genetic divergence; Genetic diversity; Genotype; Glucose; Glucose tolerance; Glucose Tolerance Test; Glycated Hemoglobin - metabolism; Heritability; Human Physiology; Humans; Hypotheses; Insulin; Insulin - metabolism; Insulin resistance; Insulin Resistance - physiology; Internal Medicine; Laboratory testing; Medicine; Medicine & Public Health; Metabolic Diseases; Native North Americans; Natural selection; Obesity; Obesity - metabolism; Phenotypic divergence; Obesity; Type 2 diabetes mellitus; Natural selection