Cytokines as therapeutic targets for cardio- and cerebrovascular diseases
Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality worldwide. In this context, inflammation is involved in the chronic process leading atherosclerotic plaque formation and its complications, as...
Saved in:
| Published in | Basic research in cardiology Vol. 116; no. 1; p. 23 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Berlin/Heidelberg
Springer Berlin Heidelberg
01.12.2021
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0300-8428 1435-1803 1435-1803 |
| DOI | 10.1007/s00395-021-00863-x |
Cover
| Abstract | Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality worldwide. In this context, inflammation is involved in the chronic process leading atherosclerotic plaque formation and its complications, as well as in the maladaptive response to acute ischemic events. For this reason, modulation of inflammation is nowadays seen as a promising therapeutic strategy to counteract the burden of cardio- and cerebrovascular disease. Being produced and recognized by both inflammatory and vascular cells, the complex network of cytokines holds key functions in the crosstalk of these two systems and orchestrates the progression of atherothrombosis. By binding to membrane receptors, these soluble mediators trigger specific intracellular signaling pathways eventually leading to the activation of transcription factors and a deep modulation of cell function. Both stimulatory and inhibitory cytokines have been described and progressively reported as markers of disease or interesting therapeutic targets in the cardiovascular field. Nevertheless, cytokine inhibition is burdened by harmful side effects that will most likely prevent its chronic use in favor of acute administrations in well-selected subjects at high risk. Here, we summarize the current state of knowledge regarding the modulatory role of cytokines on atherosclerosis, myocardial infarction, and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and the potential implication of these advances into daily clinical practice. |
|---|---|
| AbstractList | Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality worldwide. In this context, inflammation is involved in the chronic process leading atherosclerotic plaque formation and its complications, as well as in the maladaptive response to acute ischemic events. For this reason, modulation of inflammation is nowadays seen as a promising therapeutic strategy to counteract the burden of cardio- and cerebrovascular disease. Being produced and recognized by both inflammatory and vascular cells, the complex network of cytokines holds key functions in the crosstalk of these two systems and orchestrates the progression of atherothrombosis. By binding to membrane receptors, these soluble mediators trigger specific intracellular signaling pathways eventually leading to the activation of transcription factors and a deep modulation of cell function. Both stimulatory and inhibitory cytokines have been described and progressively reported as markers of disease or interesting therapeutic targets in the cardiovascular field. Nevertheless, cytokine inhibition is burdened by harmful side effects that will most likely prevent its chronic use in favor of acute administrations in well-selected subjects at high risk. Here, we summarize the current state of knowledge regarding the modulatory role of cytokines on atherosclerosis, myocardial infarction, and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and the potential implication of these advances into daily clinical practice. Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality worldwide. In this context, inflammation is involved in the chronic process leading atherosclerotic plaque formation and its complications, as well as in the maladaptive response to acute ischemic events. For this reason, modulation of inflammation is nowadays seen as a promising therapeutic strategy to counteract the burden of cardio- and cerebrovascular disease. Being produced and recognized by both inflammatory and vascular cells, the complex network of cytokines holds key functions in the crosstalk of these two systems and orchestrates the progression of atherothrombosis. By binding to membrane receptors, these soluble mediators trigger specific intracellular signaling pathways eventually leading to the activation of transcription factors and a deep modulation of cell function. Both stimulatory and inhibitory cytokines have been described and progressively reported as markers of disease or interesting therapeutic targets in the cardiovascular field. Nevertheless, cytokine inhibition is burdened by harmful side effects that will most likely prevent its chronic use in favor of acute administrations in well-selected subjects at high risk. Here, we summarize the current state of knowledge regarding the modulatory role of cytokines on atherosclerosis, myocardial infarction, and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and the potential implication of these advances into daily clinical practice.Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality worldwide. In this context, inflammation is involved in the chronic process leading atherosclerotic plaque formation and its complications, as well as in the maladaptive response to acute ischemic events. For this reason, modulation of inflammation is nowadays seen as a promising therapeutic strategy to counteract the burden of cardio- and cerebrovascular disease. Being produced and recognized by both inflammatory and vascular cells, the complex network of cytokines holds key functions in the crosstalk of these two systems and orchestrates the progression of atherothrombosis. By binding to membrane receptors, these soluble mediators trigger specific intracellular signaling pathways eventually leading to the activation of transcription factors and a deep modulation of cell function. Both stimulatory and inhibitory cytokines have been described and progressively reported as markers of disease or interesting therapeutic targets in the cardiovascular field. Nevertheless, cytokine inhibition is burdened by harmful side effects that will most likely prevent its chronic use in favor of acute administrations in well-selected subjects at high risk. Here, we summarize the current state of knowledge regarding the modulatory role of cytokines on atherosclerosis, myocardial infarction, and stroke. Then, we discuss evidence from clinical trials specifically targeting cytokines and the potential implication of these advances into daily clinical practice. |
| ArticleNumber | 23 |
| Author | Carbone, Federico Ministrini, Stefano Montecucco, Fabrizio Liberale, Luca Camici, Giovanni G. |
| Author_xml | – sequence: 1 givenname: Luca orcidid: 0000-0003-1472-7975 surname: Liberale fullname: Liberale, Luca email: luca.liberale@uzh.ch organization: Center for Molecular Cardiology, University of Zürich, First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa – sequence: 2 givenname: Stefano surname: Ministrini fullname: Ministrini, Stefano organization: First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Internal Medicine, Angiology and Atherosclerosis, Department of Medicine and Surgery, University of Perugia – sequence: 3 givenname: Federico surname: Carbone fullname: Carbone, Federico organization: First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino Genoa, Italian Cardiovascular Network – sequence: 4 givenname: Giovanni G. surname: Camici fullname: Camici, Giovanni G. organization: Center for Molecular Cardiology, University of Zürich, Department of Cardiology, University Heart Center, University Hospital Zurich, Department of Research and Education, University Hospital Zurich – sequence: 5 givenname: Fabrizio surname: Montecucco fullname: Montecucco, Fabrizio organization: IRCCS Ospedale Policlinico San Martino Genoa, Italian Cardiovascular Network, First Clinic of Internal Medicine, Department of Internal Medicine and Centre of Excellence for Biomedical Research (CEBR), University of Genoa |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33770265$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kU9v1DAQxS1URLeFL8ABReLCJTC2Y8e5IKEVlEqVuMDZmjjjrUs2Xmynar892W7Lnx56msP83tObeSfsaIoTMfaaw3sO0H7IALJTNQheAxgt65tnbMUbqWpuQB6xFUiA2jTCHLOTnK8AeKM1f8GOpWxbEFqt2Pn6tsSfYaJcYa7KJSXc0VyCqwqmDZVc-Zgqh2kIsa5wGipHifoUrzG7ecRUDSETZsov2XOPY6ZX9_OU_fjy-fv6a33x7ex8_emidk3blFq06BvvW0I50ADaNa6Twg2dVqQ1KuReGA7aN4PEXvVe9saDcX2DA--kkafs48F3N_dbGhxNJeFodylsMd3aiMH-v5nCpd3Ea9t2XWuEXAze3Ruk-GumXOw2ZEfjiBPFOVuhQIvlP8AX9O0j9CrOaVrO21NKtYp3sFBv_k30J8rDlxfAHACXYs6JvHWhYAlxHzCMloPdF2oPhdqlUHtXqL1ZpOKR9MH9SZE8iPICTxtKf2M_ofoNQNq01w |
| CitedBy_id | crossref_primary_10_2147_JIR_S399021 crossref_primary_10_3746_pnf_2024_29_3_288 crossref_primary_10_1186_s12877_024_05304_7 crossref_primary_10_14336_AD_2021_0604 crossref_primary_10_4103_jicc_jicc_9_24 crossref_primary_10_1007_s13311_023_01368_2 crossref_primary_10_1111_cns_14289 crossref_primary_10_3390_nu15071672 crossref_primary_10_2147_IJN_S439728 crossref_primary_10_1016_j_archger_2023_105172 crossref_primary_10_1007_s00018_022_04307_0 crossref_primary_10_3389_fphar_2022_1057918 crossref_primary_10_1007_s00395_022_00948_1 crossref_primary_10_3390_biomedicines11071903 crossref_primary_10_1016_j_ebiom_2022_104054 crossref_primary_10_3390_antiox10121958 crossref_primary_10_2147_JIR_S457340 crossref_primary_10_1007_s11739_023_03201_2 crossref_primary_10_1111_apm_13479 crossref_primary_10_1007_s12265_024_10548_0 crossref_primary_10_3390_antiox13101180 crossref_primary_10_1016_j_biopha_2023_115589 crossref_primary_10_1016_j_nano_2021_102434 crossref_primary_10_1007_s00395_022_00971_2 crossref_primary_10_1007_s12265_022_10326_w crossref_primary_10_1016_j_ijbiomac_2024_138533 crossref_primary_10_3390_ijms231911066 crossref_primary_10_1016_j_jpba_2023_115754 crossref_primary_10_3389_fphar_2023_1038906 crossref_primary_10_1186_s12964_023_01368_x crossref_primary_10_26724_2079_8334_2022_4_82_153_157 crossref_primary_10_1016_j_neuint_2021_105114 crossref_primary_10_1016_j_dci_2021_104226 crossref_primary_10_3390_cancers16081487 crossref_primary_10_1016_j_hermed_2024_100884 crossref_primary_10_1093_cvr_cvae178 crossref_primary_10_3389_fcvm_2022_832014 crossref_primary_10_3390_ijms22115656 crossref_primary_10_1038_s41598_024_51496_8 crossref_primary_10_1016_j_cpnec_2024_100226 crossref_primary_10_3389_fcvm_2023_1158098 crossref_primary_10_4252_wjsc_v16_i12_1022 crossref_primary_10_1016_j_cclet_2022_04_081 crossref_primary_10_1016_j_amjms_2024_08_001 crossref_primary_10_1161_CIRCULATIONAHA_123_063760 crossref_primary_10_1016_j_intimp_2021_108204 crossref_primary_10_3389_fcell_2022_926086 crossref_primary_10_3389_fneur_2024_1372431 crossref_primary_10_3389_fpsyt_2023_1215173 crossref_primary_10_3390_ph17010109 crossref_primary_10_1016_j_heliyon_2024_e39162 crossref_primary_10_3389_fimmu_2021_758272 crossref_primary_10_1093_cvr_cvae246 crossref_primary_10_1371_journal_pone_0305532 crossref_primary_10_1016_j_ejphar_2023_175965 crossref_primary_10_1016_j_jacc_2021_12_017 crossref_primary_10_3390_molecules28155904 crossref_primary_10_1007_s11655_023_3643_y crossref_primary_10_3390_nu13093047 crossref_primary_10_3389_fcvm_2023_1110742 |
| Cites_doi | 10.1016/j.cardiores.2005.01.001 10.1074/jbc.272.31.19569 10.1073/pnas.86.17.6753 10.1097/00004647-199702000-00013 10.3390/jcm8122072 10.1093/eurheartj/ehx239 10.1038/s41586-019-0948-2 10.1161/CIRCULATIONAHA.118.038010 10.1016/j.jhep.2016.02.004 10.1371/journal.pone.0011765 10.1523/JNEUROSCI.23-25-08692.2003 10.3390/ijms21176009 10.1007/BF03020341 10.2174/0929867324666170303123734 10.1096/fj.03-1148fje 10.1161/CIRCRESAHA.119.315185 10.1161/01.hyp.33.1.183 10.1016/j.amjcard.2014.11.003 10.1074/jbc.RA118.004220 10.1016/j.it.2014.12.008 10.3324/haematol.2020.252395 10.12688/f1000research.19308.2 10.1016/j.cardiores.2005.01.008 10.1074/jbc.270.16.9558 10.1093/cvr/cvaa211 10.1371/journal.pone.0179065 10.1006/exnr.1996.0059 10.1186/s12974-015-0330-8 10.1080/09629359990298 10.1097/00004647-199609000-00017 10.1038/s41467-020-16439-7 10.4049/jimmunol.166.4.2674 10.1093/cvr/cvz042 10.1161/01.cir.101.9.1019 10.1097/01.fjc.0000250079.46526.38 10.1152/ajpheart.00374.2002 10.1016/j.bbrc.2009.07.152 10.1177/0271678X15606714 10.1523/JNEUROSCI.5505-08.2009 10.1038/srep29291 10.1016/j.neurobiolaging.2015.06.015 10.1152/ajpheart.2000.278.6.H1823 10.1523/JNEUROSCI.21-15-05528.2001 10.1161/01.RES.0000229685.37402.80 10.1182/blood.V75.6.1305.1305 10.1161/CIRCULATIONAHA.120.046301 10.1016/j.biocel.2020.105735 10.1161/ATVBAHA.107.159327 10.1161/01.atv.19.10.2364 10.1016/j.biopha.2018.12.031 10.1016/j.atherosclerosis.2004.11.016 10.1172/JCI118476 10.1186/s12974-014-0203-6 10.1038/s41586-020-2403-9 10.1136/openhrt-2019-001108 10.1136/jnnp.2004.054882 10.1161/01.RES.0000255031.15793.86 10.1161/STROKEAHA.115.012079 10.1161/01.atv.19.3.611 10.1038/sj.jcbfm.9600537 10.1097/FJC.0000000000000658 10.1016/s0022-4804(02)00038-0 10.1093/brain/aws075 10.1016/j.trsl.2016.12.003 10.3389/fcvm.2019.00140 10.1038/mi.2016.47 10.1007/s00296-017-3844-9 10.1161/01.CIR.0000077913.60364.D2 10.1016/0006-291x(92)91793-p 10.1016/j.healun.2004.06.021 10.1161/hq0302.104905 10.2174/1381612822666160822124546 10.2174/157340208786241336 10.1016/s1388-9842(02)00121-6 10.1172/JCI43713 10.1096/fj.03-0331fje 10.1152/ajplung.1990.258.2.L57 10.1161/CIRCULATIONAHA.108.802918 10.1161/01.cir.103.21.2610 10.1016/j.jacc.2019.05.024 10.1016/j.yjmcc.2011.06.022 10.1097/01.fjc.0000151930.12026.b7 10.1038/s41419-019-1716-9 10.1007/s10557-008-6130-y 10.1186/1475-2840-12-12 10.1007/s10741-010-9180-8 10.1016/0021-9150(94)05503-b 10.1016/j.brainres.2009.06.081 10.1016/s0002-8703(99)70375-3 10.1136/heartjnl-2013-303648 10.1126/science.aal3535 10.1159/000111367 10.1016/j.immuni.2018.09.011 10.1002/path.2305 10.1016/j.atherosclerosis.2007.06.015 10.1016/j.neulet.2014.07.003 10.1161/01.ATV.0000143933.20616.1b 10.1016/j.ymgme.2008.11.166 10.3858/emm.2009.41.10.082 10.1161/01.RES.0000177893.24574.13 10.1016/S0002-9440(10)63471-2 10.1097/00004647-199901000-00010 10.1152/ajpheart.00166.2007 10.1038/nm.2513 10.1111/j.1471-4159.2005.03227.x 10.2337/dc11-2219 10.1002/art.1780361206 10.1002/jcp.22142 10.1161/JAHA.117.008257 10.1056/NEJMoa1707914 10.1155/2018/8430123 10.1152/ajplung.00109.2006 10.1126/scitranslmed.aad5330 10.1152/ajpheart.00346.2014 10.1371/journal.pone.0027923 10.1084/jem.160.2.618 10.1161/STROKEAHA.118.020750 10.1093/eurheartj/ehz961 10.1056/NEJM197608122950707 10.1161/CIRCULATIONAHA.107.740233 10.1161/ATVBAHA.111.229997 10.1161/CIRCRESAHA.108.178475 10.1016/s0735-1097(01)01591-1 10.1186/1742-2094-5-46 10.1093/eurheartj/ehy286 10.1152/ajpheart.00641.2003 10.1161/01.CIR.0000155622.68580.DC 10.1113/expphysiol.2012.069831 10.1007/s00395-004-0509-0 10.1016/j.amjcard.2018.07.002 10.1161/01.cir.97.3.242 10.1097/FJC.0000000000000106 10.1161/01.res.85.8.e17 10.1016/j.bbi.2009.02.015 10.1016/s0735-1097(02)01738-2 10.1038/jcbfm.2012.97 10.1161/ATVBAHA.109.187146 10.1007/s00296-017-3842-y 10.1152/ajpcell.00157.2006 10.1161/ATVBAHA.119.312287 10.1161/01.res.0000018941.10726.fa 10.1007/s10557-012-6389-x 10.1186/s12974-019-1599-9 10.1016/j.yjmcc.2008.08.014 10.1161/CIRCRESAHA.108.173963 10.3109/00207454.2014.980906 10.1111/j.1600-065X.2008.00714.x 10.1007/s12016-018-8714-z 10.1007/s11914-020-00599-y 10.1152/ajpheart.00700.2006 10.1161/01.ATV.0000064374.15232.C3 10.1006/excr.1994.1296 10.1016/j.cardiores.2005.02.016 10.1016/j.amjcard.2013.01.287 10.1007/s00395-017-0622-5 10.1161/JAHA.117.008024 10.1100/2012/737585 10.1161/01.atv.16.12.1573 10.1007/s00395-019-0739-9 10.1155/2015/759610 10.1007/s00401-016-1541-5 10.1038/nature01323 10.1016/j.gene.2020.144900 10.1161/CIRCRESAHA.113.301934 10.1523/JNEUROSCI.22-01-00038.2002 10.1038/jcbfm.2013.100 10.1016/s0006-8993(97)00981-5 10.1007/s00011-016-0931-4 10.1016/j.jaut.2012.07.009 10.1016/j.jacbts.2017.06.005 10.1093/eurheartj/ehw171 10.1002/adma.201904607 10.3899/jrheum.200265 10.1038/sj.jcbfm.9600086 10.1111/j.1742-4658.2005.04979.x 10.1038/s41598-019-38670-z 10.1161/01.CIR.0000148135.08582.97 10.1182/blood-2005-03-1247 10.1161/01.str.31.7.1715 10.4062/biomolther.2016.050 10.1111/jnc.13422 10.1016/s0304-3940(98)00537-0 10.1007/s11886-018-1067-7 10.1016/j.it.2010.05.005 10.1161/hc37t1.094871 10.1016/j.vph.2016.08.004 10.1016/j.yjmcc.2004.12.015 10.1038/cdd.2011.93 10.1161/JAHA.119.014941 10.1160/TH16-08-0593 10.1186/ar4064 10.1016/j.immuni.2019.03.007 10.1161/ATVBAHA.118.312037 10.1016/0021-9150(91)90066-c 10.1113/expphysiol.2005.030734 10.1038/labinvest.3700322 10.7150/ijbs.4679 10.1093/eurheartj/ehz008 10.1155/2015/189292 10.1006/bbrc.1997.6436 10.1161/CIRCULATIONAHA.108.846105 10.1161/01.ATV.0000134378.86443.cd 10.1160/TH17-09-0630 10.1038/jcbfm.2013.155 10.1152/ajpheart.01210.2003 10.1161/01.atv.21.5.825 10.1111/j.1365-2141.1995.tb05348.x 10.1084/jem.185.5.933 10.1097/FJC.0b013e3181c87e53 10.1073/pnas.94.5.2007 10.1089/107999001750169871 10.1111/j.1471-4159.2009.06098.x 10.4049/jimmunol.1001623 10.1152/ajpcell.2002.282.1.C144 10.1007/s00395-008-0757-5 10.2353/ajpath.2008.070974 10.1038/cddis.2017.470 10.1089/wound.2013.0461 10.1016/j.yjmcc.2004.03.012 10.1177/0271678X15610339 10.1136/annrheumdis-2014-206624 10.1074/jbc.271.42.26174 10.1182/blood.V83.1.113.113 10.1371/journal.pone.0167195 10.1007/112_2020_26 10.1161/01.str.28.6.1233 10.1124/molpharm.120.000056 10.1126/scitranslmed.3006133 10.3390/biom9090416 10.1152/ajpcell.1993.264.4.C894 10.1161/CIRCRESAHA.108.188243 10.7150/ntno.37391 10.1016/j.bbamcr.2011.01.034 10.3892/etm.2015.2363 10.1161/01.ATV.0000127025.48140.a3 10.1097/FJC.0000000000000452 10.4049/jimmunol.172.1.567 10.1016/s1074-7613(04)00046-9 10.4161/cc.11.1.18473 10.1093/eurheartj/ehaa099 10.1016/j.cardiores.2005.06.026 10.1016/j.bbrc.2009.05.046 10.1038/nature11260 10.1152/ajpheart.00036.2004 10.1523/JNEUROSCI.1685-15.2015 10.1161/CIRCULATIONAHA.109.924886 10.1161/STROKEAHA.115.010001 10.1161/CIRCRESAHA.110.235713 10.4049/jimmunol.0901126 10.1016/j.bbi.2017.05.019 10.3390/ijms20236008 10.1189/jlb.70.2.192 10.4049/jimmunol.143.12.4015 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2021 The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2021 – notice: The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8AO 8FD 8FI 8FJ 8FK ABUWG AFKRA BENPR CCPQU FR3 FYUFA GHDGH K9. M0S M1P M7Z P64 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| DOI | 10.1007/s00395-021-00863-x |
| DatabaseName | Springer Nature OA Free Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Technology Research Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central ProQuest One Community College Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Medical Database Biochemistry Abstracts 1 Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Technology Research Database ProQuest One Academic Middle East (New) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition Biochemistry Abstracts 1 Engineering Research Database ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | Technology Research Database MEDLINE - Academic CrossRef MEDLINE |
| Database_xml | – sequence: 1 dbid: C6C name: Springer Nature OA Free Journals url: http://www.springeropen.com/ sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1435-1803 |
| ExternalDocumentID | PMC7997823 33770265 10_1007_s00395_021_00863_x |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GrantInformation_xml | – fundername: Rete Cardiologica of the Italian Ministry of Health – fundername: Sheikh Khalifa's Foundation – fundername: Alfred and Annemarie von Sick Grants for Translational and Clinical Research Cardiology and Oncology – fundername: Universität Zürich – fundername: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung grantid: 310030_197510 funderid: http://dx.doi.org/10.13039/501100001711 – fundername: Schweizerische Herzstiftung funderid: http://dx.doi.org/10.13039/501100004362 – fundername: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung grantid: 310030_197510 – fundername: ; – fundername: ; grantid: 310030_197510 |
| GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C .86 .GJ .VR 06C 06D 0R~ 0VY 1N0 1SB 2.D 203 23N 28- 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5RE 5VS 67Z 6NX 78A 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDZT ABECU ABFTV ABHLI ABHQN ABJNI ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHXU ACIWK ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACUDM ACZOJ ADBBV ADHHG ADHIR ADIMF ADINQ ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFIE AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFEXP AFKRA AFLOW AFQWF AFRAH AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ AXYYD AZFZN B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BSONS BVXVI C6C CAG CCPQU COF CSCUP DDRTE DL5 DNIVK DPUIP DU5 EBD EBLON EBS EIOEI EJD EMB EMOBN EN4 ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GRRUI GXS H13 HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ IHE IJ- IKXTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH LAS LLZTM M1P M4Y MA- N2Q N9A NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM OVD P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R89 R9I RHV RIG RNI ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TEORI TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 YLTOR Z45 Z7U Z82 Z87 Z8O Z8V Z91 ZGI ZMTXR ZOVNA ~EX ~KM AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC ADHKG AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT CGR CUY CVF ECM EIF NPM 7XB 8FD 8FK ABRTQ FR3 K9. M7Z P64 PJZUB PKEHL PPXIY PQEST PQUKI PRINS 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c474t-27af4ff7ea3ded06c4c932cd965e66a5a1f28106f4d3ab5bf3b8f08cb4ad19383 |
| IEDL.DBID | C6C |
| ISSN | 0300-8428 1435-1803 |
| IngestDate | Thu Aug 21 13:32:16 EDT 2025 Sat Sep 27 21:18:46 EDT 2025 Sat Aug 23 14:32:23 EDT 2025 Wed Feb 19 02:26:29 EST 2025 Tue Jul 01 02:27:16 EDT 2025 Thu Apr 24 23:07:54 EDT 2025 Fri Feb 21 02:46:25 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Cardiovascular disease Cytokines Interleukins IL-1 IL-6 Cerebrovascular disease |
| Language | English |
| License | Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c474t-27af4ff7ea3ded06c4c932cd965e66a5a1f28106f4d3ab5bf3b8f08cb4ad19383 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0003-1472-7975 |
| OpenAccessLink | https://doi.org/10.1007/s00395-021-00863-x |
| PMID | 33770265 |
| PQID | 2505575190 |
| PQPubID | 34036 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7997823 proquest_miscellaneous_2506277001 proquest_journals_2505575190 pubmed_primary_33770265 crossref_citationtrail_10_1007_s00395_021_00863_x crossref_primary_10_1007_s00395_021_00863_x springer_journals_10_1007_s00395_021_00863_x |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20211200 |
| PublicationDateYYYYMMDD | 2021-12-01 |
| PublicationDate_xml | – month: 12 year: 2021 text: 20211200 |
| PublicationDecade | 2020 |
| PublicationPlace | Berlin/Heidelberg |
| PublicationPlace_xml | – name: Berlin/Heidelberg – name: Germany – name: Heidelberg |
| PublicationTitle | Basic research in cardiology |
| PublicationTitleAbbrev | Basic Res Cardiol |
| PublicationTitleAlternate | Basic Res Cardiol |
| PublicationYear | 2021 |
| Publisher | Springer Berlin Heidelberg Springer Nature B.V |
| Publisher_xml | – name: Springer Berlin Heidelberg – name: Springer Nature B.V |
| References | Liberale, Dallegri, Montecucco, Carbone (CR141) 2017; 117 Dutta, Courties, Wei, Leuschner, Gorbatov, Robbins, Iwamoto, Thompson, Carlson, Heidt, Majmudar, Lasitschka, Etzrodt, Waterman, Waring, Chicoine, van der Laan, Niessen, Piek, Rubin, Butany, Stone, Katus, Murphy, Morrow, Sabatine, Vinegoni, Moskowitz, Pittet, Libby, Lin, Swirski, Weissleder, Nahrendorf (CR62) 2012; 487 Toldo, Mauro, Cutter, Van Tassell, Mezzaroma, Del Buono, Prestamburgo, Potere, Abbate (CR226) 2019; 73 Salmeron, Maniskas, Edwards, Wong, Rajkovic, Trout, Rahman, Hamilton, Fraser, Pinteaux, Bix (CR200) 2019; 16 Abbate, Salloum, Vecile, Das, Hoke, Straino, Biondi-Zoccai, Houser, Qureshi, Ownby, Gustini, Biasucci, Severino, Capogrossi, Vetrovec, Crea, Baldi, Kukreja, Dobrina (CR3) 2008; 117 Chung, Packer, Lo, Fasanmade, Willerson, Anti (CR45) 2003; 107 Scheller, Chalaris, Schmidt-Arras, Rose-John (CR203) 2011; 1813 Gu, Yang, Bonde, DiPaula, Fox-Talbot, Becker (CR93) 2006; 48 Ross, Glomset (CR195) 1976; 295 Wang, Guo, Ding, Mehta (CR242) 2018 Qin, Wang, Zhou, Wang, Wang, Wang (CR187) 2020; 755 Kober, Canault, Peiretti, Mueller, Kopp, Alessi, Cozzone, Nalbone, Bernard (CR127) 2007; 195 Williams, Bradley, Smith, Foxwell (CR244) 2004; 172 Akarasereenont, Techatrisak, Chotewuttakorn, Thaworn (CR7) 1999; 8 Gao, Liu, Yu, Yang, Li, Sun, Yan, Cai, Gao, Xiong, Wang, Tao (CR77) 2015; 308 Lim, Um, Park, Lee, Kwon (CR149) 2009; 41 Bujak, Dobaczewski, Chatila, Mendoza, Li, Reddy, Frangogiannis (CR31) 2008; 173 Toldo, Mezzaroma, Van Tassell, Farkas, Marchetti, Voelkel, Abbate (CR228) 2013; 98 Angelini, Hyun, Grigoryev, Garg, Gong, Singh, Passaniti, Hasday, Goldblum (CR11) 2006; 291 Robert, Chapelain, Jean, Neliat (CR194) 1992; 182 Everett, Cornel, Lainscak, Anker, Abbate, Thuren, Libby, Glynn, Ridker (CR70) 2019; 139 Guo, Li, Tao, Li, Liu, Dou, Jin, Li, Huang, Hu, Zhang (CR95) 2019; 31 Ooboshi, Ibayashi, Shichita, Kumai, Takada, Ago, Arakawa, Sugimori, Kamouchi, Kitazono, Iida (CR175) 2005; 111 Sun, Ren, Xiong, Chen, Zhao, Wang, Zhou, Han, Chen, Li, Kang, Zhu (CR220) 2017; 8 Liberale, Montecucco, Tardif, Libby, Camici (CR146) 2020; 41 Potteaux, Esposito, van Oostrom, Brun, Ardouin, Groux, Tedgui, Mallat (CR186) 2004; 24 Doran, Meller, McNamara (CR61) 2008; 28 Lawler, Bhatt, Godoy, Luscher, Bonow, Verma, Ridker (CR133) 2020 Gurantz, Yndestad, Halvorsen, Lunde, Omens, Ueland, Aukrust, Moore, Kjekshus, Greenberg (CR97) 2005; 67 Schreyer, Peschon, LeBoeuf (CR207) 1996; 271 Isoda, Sawada, Ishigami, Matsuki, Miyazaki, Kusuhara, Iwakura, Ohsuzu (CR110) 2004; 24 Abbate, Kontos, Abouzaki, Melchior, Thomas, Van Tassell, Oddi, Carbone, Trankle, Roberts, Mueller, Gambill, Christopher, Markley, Vetrovec, Dinarello, Biondi-Zoccai (CR1) 2015; 115 Goetze, Xi, Kawano, Kawano, Fleck, Hsueh, Law (CR86) 1999; 33 Boutin, LeFeuvre, Horai, Asano, Iwakura, Rothwell (CR28) 2001; 21 Schonbeck, Mach, Bonnefoy, Loppnow, Flad, Libby (CR206) 1997; 272 Krishnamurthy, Rajasingh, Lambers, Qin, Losordo, Kishore (CR129) 2009; 104 Yan, You, Chen, Liao, Sun (CR248) 2008; 103 Dong, Fujii, Imagawa, Matsumoto, Matsushita, Todo, Tsutsui, Sobel (CR60) 2007; 292 Coletta, Clark, Banarjee, Cleland (CR52) 2002; 4 Danzaki, Matsui, Ikesue, Ohta, Ito, Kanayama, Kurotaki, Morimoto, Iwakura, Yagita, Tsutsui, Uede (CR54) 2012; 32 Mog, Asase, Chaplin, Gao, Rajagopalan, Maiseyeu (CR165) 2019; 3 Coomes, Kannan, Pelly, Entwistle, Guidi, Perez-Lloret, Nikolov, Müller, Wilson (CR53) 2017; 10 Gulick, Chung, Pieper, Lange, Schreiner (CR94) 1989; 86 Moe, Marin-Garcia, Konig, Goldenthal, Lu, Feng (CR164) 2004; 287 Arango-Davila, Vera, Londono, Echeverri, Canas, Cardozo, Orozco, Rengifo, Canas (CR13) 2015; 125 Alexander, Moehle, Johnson, Yang, Lee, Jackson, Owens (CR9) 2012; 122 Nash, McGrath, Cartland, Patel, Kavurma (CR169) 2019; 115 Zhao, Newland, Mallat (CR252) 2020; 40 Amor, Feucht, Leibold, Ho, Zhu, Alonso-Curbelo, Mansilla-Soto, Boyer, Li, Giavridis, Kulick, Houlihan, Peerschke, Friedman, Ponomarev, Piersigilli, Sadelain, Lowe (CR10) 2020; 583 Kleveland, Kunszt, Bratlie, Ueland, Broch, Holte, Michelsen, Bendz, Amundsen, Espevik, Aakhus, Damas, Aukrust, Wiseth, Gullestad (CR126) 2016; 37 Kisiel, Kruszewski, Juszkiewicz, Raczkiewicz, Bachta, Tlustochowicz, Staniszewska-Varga, Klos, Duda, Boguslawska-Walecka, Ploski, Tlustochowicz (CR122) 2015; 2015 Pinderski, Fischbein, Subbanagounder, Fishbein, Kubo, Cheroutre, Curtiss, Berliner, Boisvert (CR183) 2002; 90 Harouki, Nicol, Remy-Jouet, Henry, Dumesnil, Lejeune, Renet, Golding, Djerada, Wecker, Bolduc, Bouly, Roussel, Richard, Mulder (CR101) 2017; 2 Zhang, Zhang, Ungvari, Zhang (CR251) 2009; 29 Clark, McMahon, Gueorguieva, Rowland, Scarth, Georgiou, Tyrrell, Hopkins, Rothwell (CR46) 2008; 28 Ip, Hoshi, Shouval, Snapper, Medzhitov (CR109) 2017; 356 Kume, Amano, Yamada, Kanazawa, Ohta, Hatta, Amano, Kuwaba (CR130) 2017; 37 Boada, Zinger, Tsao, Zhao, Martinez, Hartman, Naoi, Sukhoveshin, Sushnitha, Molinaro, Trachtenberg, Cooke, Tasciotti (CR23) 2020; 126 Merhi-Soussi, Kwak, Magne, Chadjichristos, Berti, Pelli, James, Mach, Gabay (CR163) 2005; 66 Clausen, Lambertsen, Dagnaes-Hansen, Babcock, von Linstow, Meldgaard, Kristensen, Deierborg, Finsen (CR51) 2016; 131 Bahrami, Liberale, Reiner, Carbone, Montecucco, Sahebkar (CR15) 2020; 177 Berthonneche, Sulpice, Boucher, Gouraud, de Leiris, O'Connor, Herbert, Janiak (CR21) 2004; 287 Tosato, Jones (CR230) 1990; 75 Alard, Ortega-Gomez, Wichapong, Bongiovanni, Horckmans, Megens, Leoni, Ferraro, Rossaint, Paulin, Ng, Ippel, Suylen, Hinkel, Blanchet, Gaillard, D’Amico, von Hundelshausen, Zarbock, Scheiermann, Hackeng, Steffens, Kupatt, Nicolaes, Weber, Soehnlein (CR8) 2015; 7 Feng, Wang, Yang (CR72) 2015; 9 Jong, Ten Cate, Linnenbank, de Boer, Reitsma, de Winter, Zuurbier (CR113) 2016; 65 Bonaventura, Liberale, Carbone, Vecchie, Diaz-Canestro, Camici, Montecucco, Dallegri (CR25) 2018; 118 Wang, Wu, Siegel, Egan, Billah (CR240) 1995; 270 Bonetti, Diaz-Canestro, Liberale, Crucet, Akhmedov, Merlini, Reiner, Gobbato, Stivala, Kollias, Ruschitzka, Luscher, Beer, Camici (CR26) 2019; 9 Belosjorow, Bolle, Duschin, Heusch, Schulz (CR17) 2003; 284 Liberale, Montecucco, Schwarz, Luscher, Camici (CR145) 2020 Liberale, Holy, Akhmedov, Bonetti, Nietlispach, Matter, Mach, Montecucco, Beer, Paneni, Ruschitzka, Libby, Luscher, Camici (CR143) 2019 Toldo, Mezzaroma, Bressi, Marchetti, Carbone, Sonnino, Van Tassell, Abbate (CR227) 2014; 64 Gronhoj, Clausen, Fenger, Lambertsen, Finsen (CR91) 2017; 65 Zhao, Wang, Sun, Zhang, Edwards, Aronowski (CR253) 2015; 35 Goldblum, Sun (CR88) 1990; 258 Lee, Kam, Kim, Kim, Kim, Cheon, Koo (CR135) 2017; 25 Branen, Hovgaard, Nitulescu, Bengtsson, Nilsson, Jovinge (CR29) 2004; 24 Mauro, Mezzaroma, Torrado, Kundur, Joshi, Stroud, Quaini, Lagrasta, Abbate, Toldo (CR159) 2017; 69 Cavelti-Weder, Babians-Brunner, Keller, Stahel, Kurz-Levin, Zayed, Solinger, Mandrup-Poulsen, Dinarello, Donath (CR40) 2012; 35 Hosomi, Ban, Naya, Takahashi, Guo, Song, Kohno (CR104) 2005; 25 Ottonello, Morone, Dapino, Dallegri (CR176) 1995; 91 Hawrylowicz, Santoro, Platt, Unanue (CR103) 1989; 143 Carbone, Liberale, Bonaventura, Cea, Montecucco (CR37) 2016; 22 Berry, Woo, Pirolli, Bish, Moise, Burdick, Morine, Jayasankar, Gardner, Sweeney (CR20) 2004; 23 Kleinbongard, Bose, Baars, Mohlenkamp, Konorza, Schoner, Elter-Schulz, Eggebrecht, Degen, Haude, Levkau, Schulz, Erbel, Heusch (CR123) 2011; 108 Carbone, Satta, Burger, Roth, Lenglet, Pagano, Lescuyer, Bertolotto, Spinella, Pane, Palombo, Pende, Dallegri, Mach, Vuilleumier, Montecucco (CR38) 2016; 85 Elhage, Maret, Pieraggi, Thiers, Arnal, Bayard (CR63) 1998; 97 Chi, Li, Stehno-Bittel, Gao, Morrison, Stechschulte, Dileepan (CR43) 2001; 21 Polunovsky, Wendt, Ingbar, Peterson, Bitterman (CR185) 1994; 214 Schumacher, Naga Prasad (CR210) 2018; 20 King, Balaji, Le, Crombleholme, Keswani (CR118) 2014; 3 Zhu, Huang, Dai, Wang, Gao, Han, Zhang (CR254) 2019; 111 McAlpine, Kiss, Rattik, He, Vassalli, Valet, Anzai, Chan, Mindur, Kahles, Poller, Frodermann, Fenn, Gregory, Halle, Iwamoto, Hoyer, Binder, Libby, Tafti, Scammell, Nahrendorf, Swirski (CR161) 2019; 566 Smith, Hulme, Vail, Heal, Parry-Jones, Scarth, Hopkins, Hoadley, Allan, Rothwell, Hopkins, Tyrrell (CR213) 2018; 49 Newman, Castresana, Webb, Wang (CR172) 2003; 109 Tourneur, Chiocchia (CR232) 2010; 31 Grewal, Priceputu, Davignon, Bernier (CR90) 2001; 21 Ge, Hertel, Koltsova, Sorensen-Zender, Kielstein, Ley, Haller, von Vietinghoff (CR80) 2013; 113 Boniface, Blom, Liu, de Waal (CR27) 2008; 226 Ibanez, Aletras, Arai, Arheden, Bax, Berry, Bucciarelli-Ducci, Croisille, Dall'Armellina, Dharmakumar, Eitel, Fernandez-Jimenez, Friedrich, Garcia-Dorado, Hausenloy, Kim, Kozerke, Kramer, Salerno, Sanchez-Gonzalez, Sanz, Fuster (CR108) 2019; 74 Davenport, Tipping (CR55) 2003; 163 Noels, Weber, Koenen (CR173) 2019; 39 Li, Zhao, Liu, Du, Ding, Zhang, Mehta (CR137) 1999; 137 Maekawa, Wada, Kanda, Niwa, Yamada, Saito, Fujiwara, Sekikawa, Seishima (CR154) 2002; 39 Picchi, Gao, Belmadani, Potter, Focardi, Chilian, Zhang (CR180) 2006; 99 Davis, Pillai, Lawrence, Sebti, Chellappan (CR57) 2012; 11 Nawashiro, Martin, Hallenbeck (CR170) 1997; 17 Lee, Lin, Wu, Yang (CR134) 2010; 224 Thompson, Van Eldik (CR224) 2009; 1287 Baars, Konorza, Kahlert, Mohlenkamp, Erbel, Heusch, Kleinbongard (CR14) 2013; 12 Chen, Andresen, Hill, Zhang, Booth, Zhang (CR42) 2008; 4 Garcia, Liu, Relton (CR79) 1995; 147 Abbate, Salloum, Van Tassell, Vecile, Toldo, Seropian, Mezzaroma, Dobrina (CR2) 2011; 6 Liberale, Carbone, Montecucco, Sahebkar (CR140) 2020; 122 Works, Koenig, Sapolsky (CR245) 2013; 33 Hanna, Frangogiannis (CR99) 2019; 6 Schmidt-Arras, Rose-John (CR205) 2016; 64 Liberale, Montecucco, Camici, Dallegri, Vecchie, Carbone, Bonaventura (CR144) 2017; 24 Spera, Ellison, Feuerstein, Barone (CR216) 1998; 251 Spulber, Bartfai, Schultzberg (CR217) 2009; 23 Grothusen, Hagemann, Attmann, Braesen, Broch, Cremer, Schoettler (CR92) 2012; 2012 Savard, Brochu, Chevin, Guiraut, Grbic, Sebire (CR202) 2015; 12 Gertz, Kronenberg, Kalin, Baldinger, Werner, Balkaya, Eom, Hellmann-Regen, Krober, Miller, Lindauer, Laufs, Di K Danzaki (863_CR54) 2012; 32 J Zhu (863_CR254) 2019; 111 P Davenport (863_CR55) 2003; 163 T Mohr (863_CR166) 2017; 12 BH Clausen (863_CR48) 2014; 11 L Liberale (863_CR146) 2020; 41 P Kleinbongard (863_CR125) 2011; 16 FC Barone (863_CR16) 1997; 28 MH Hartman (863_CR102) 2016; 11 B Kirk (863_CR121) 2020; 18 H Tilg (863_CR225) 1994; 83 N Hosomi (863_CR104) 2005; 25 F Kober (863_CR127) 2007; 195 P Libby (863_CR138) 2002; 420 RK Sumbria (863_CR219) 2012; 32 I Perez-de Puig (863_CR179) 2013; 33 BH Clausen (863_CR50) 2008; 5 B Mog (863_CR165) 2019; 3 G Tosato (863_CR230) 1990; 75 VL King (863_CR119) 2002; 22 AP Coletta (863_CR52) 2002; 4 C Grothusen (863_CR92) 2012; 2012 K Rajamaki (863_CR188) 2010; 5 P Ruiz-Limon (863_CR197) 2017; 183 K Schultz (863_CR208) 2007; 292 V Gelfo (863_CR83) 2020 T Baars (863_CR14) 2013; 12 WKE Ip (863_CR109) 2017; 356 ES Chung (863_CR45) 2003; 107 MW Hwang (863_CR107) 2001; 38 S Ge (863_CR80) 2013; 113 IT Lee (863_CR134) 2010; 224 AR Fatkhullina (863_CR71) 2018; 49 S Toldo (863_CR229) 2012; 26 L Liberale (863_CR143) 2019 WL Thompson (863_CR224) 2009; 1287 M Canault (863_CR35) 2008; 214 L Agostini (863_CR6) 2004; 20 L Williams (863_CR244) 2004; 172 S Potteaux (863_CR186) 2004; 24 PA Spera (863_CR216) 1998; 251 Z Yang (863_CR249) 2000; 101 S Maysami (863_CR160) 2016; 36 A Abbate (863_CR3) 2008; 117 WM Jong (863_CR113) 2016; 65 T Gulick (863_CR94) 1989; 86 GT Brown (863_CR30) 2011; 186 O Touzani (863_CR233) 2002; 22 J Guo (863_CR95) 2019; 31 P Kleinbongard (863_CR124) 2012; 52 SA Huber (863_CR105) 1999; 19 S Belosjorow (863_CR17) 2003; 284 LS Boesten (863_CR24) 2005; 66 P Kleinbongard (863_CR123) 2011; 108 A Abbate (863_CR1) 2015; 115 SM Coomes (863_CR53) 2017; 10 A Picchi (863_CR180) 2006; 99 R Schulz (863_CR209) 2009; 119 CS McAlpine (863_CR161) 2019; 566 X Chen (863_CR42) 2008; 4 D Engelbertsen (863_CR67) 2018 M Sugano (863_CR218) 2004; 18 C Boada (863_CR23) 2020; 126 PM Ridker (863_CR192) 2017; 377 S Toldo (863_CR227) 2014; 64 N Harouki (863_CR101) 2017; 2 T Yamashita (863_CR247) 2005; 94 SM Schumacher (863_CR210) 2018; 20 A Skyschally (863_CR212) 2007; 100 HA Gelbard (863_CR82) 1993; 15 HC Emsley (863_CR66) 2005; 76 JH Garcia (863_CR79) 1995; 147 H Ellingsgaard (863_CR64) 2011; 17 K Isoda (863_CR110) 2004; 24 L McCulloch (863_CR162) 2019; 8 Y Monden (863_CR167) 2007; 293 B Dawn (863_CR58) 2004; 37 C Cavelti-Weder (863_CR40) 2012; 35 CM Hawrylowicz (863_CR103) 1989; 143 P Pignatelli (863_CR182) 2005; 106 A Vromman (863_CR239) 2019; 40 M Pickering (863_CR181) 2005; 90 C Amor (863_CR10) 2020; 583 MF Berry (863_CR20) 2004; 23 S Spulber (863_CR217) 2009; 23 DJ Berg (863_CR18) 2001; 166 AC Morton (863_CR168) 2005; 68 T van Es (863_CR235) 2009; 388 X Yu (863_CR250) 2005; 45 E Smith (863_CR214) 2010; 121 L Ottonello (863_CR176) 1995; 91 K Kume (863_CR130) 2017; 37 KL Lambertsen (863_CR132) 2009; 29 GG Camici (863_CR34) 2017; 38 AG Mauro (863_CR159) 2017; 69 XM Gao (863_CR78) 2019; 114 H Hara (863_CR100) 1997; 94 A Abbate (863_CR5) 2013; 111 NR Bonetti (863_CR26) 2019; 9 J Mauer (863_CR158) 2015; 36 S Sasu (863_CR201) 2000; 278 M Qin (863_CR187) 2020; 755 D Li (863_CR137) 1999; 137 C Roubille (863_CR196) 2015; 74 BW Van Tassell (863_CR236) 2010; 55 G Yan (863_CR248) 2008; 103 MP Flaherty (863_CR73) 2008; 45 HJ Sun (863_CR220) 2017; 8 AC Doran (863_CR61) 2008; 28 GJ Padfield (863_CR178) 2013; 99 M Bujak (863_CR31) 2008; 173 BH Clausen (863_CR51) 2016; 131 JH Lee (863_CR135) 2017; 25 N Bergh (863_CR19) 2009; 385 L Liberale (863_CR141) 2017; 117 L Chi (863_CR43) 2001; 21 C Berthonneche (863_CR21) 2004; 287 Z Mallat (863_CR156) 1999; 19 D Schmidt-Arras (863_CR205) 2016; 64 S Toldo (863_CR228) 2013; 98 JO Jin (863_CR112) 2013; 40 SE Goldblum (863_CR88) 1990; 258 M Liguz-Lecznar (863_CR148) 2015; 36 D Gurantz (863_CR96) 2005; 38 H Ohta (863_CR174) 2005; 180 MC Toufektsian (863_CR231) 2008; 22 MJ Elliott (863_CR65) 1993; 36 S Kany (863_CR117) 2019 S Toldo (863_CR226) 2019; 73 AQ Chen (863_CR41) 2019; 10 A King (863_CR118) 2014; 3 X Liu (863_CR150) 2016; 47 A Abbate (863_CR4) 2020; 9 S Rastogi (863_CR190) 2012; 19 B Schieffer (863_CR204) 2004; 110 L Liberale (863_CR145) 2020 AM Gorabi (863_CR89) 2019 LJ Pinderski (863_CR183) 2002; 90 JS Burchfield (863_CR32) 2008; 103 T Hamid (863_CR98) 2009; 119 Z Mallat (863_CR155) 1999; 85 A Bahrami (863_CR15) 2020; 177 JK Relton (863_CR191) 1996; 138 U Schonbeck (863_CR206) 1997; 272 A Gistera (863_CR85) 2013; 5 N Xiao (863_CR246) 2009; 96 C Gao (863_CR77) 2015; 308 MH Gronhoj (863_CR91) 2017; 65 H Kirii (863_CR120) 2003; 23 B Ibanez (863_CR108) 2019; 74 A Liesz (863_CR147) 2014; 579 R Davis (863_CR57) 2012; 11 MR Alexander (863_CR9) 2012; 122 HG Rus (863_CR198) 1991; 89 P Wang (863_CR240) 1995; 270 D Gurantz (863_CR97) 2005; 67 L Liberale (863_CR139) 2020; 142 F Carbone (863_CR36) 2020; 58 JH Lim (863_CR149) 2009; 41 N Iwata (863_CR111) 2015; 2015 X Wang (863_CR242) 2018 X Zhao (863_CR253) 2015; 35 J Venugopal (863_CR237) 2020 KE Salmeron (863_CR200) 2019; 16 B Kisiel (863_CR122) 2015; 2015 X Wang (863_CR241) 1995; 115 F Merhi-Soussi (863_CR163) 2005; 66 F Carbone (863_CR38) 2016; 85 C Erbel (863_CR68) 2009; 183 A Bonaventura (863_CR25) 2018; 118 Q Gu (863_CR93) 2006; 48 O Kleveland (863_CR126) 2016; 37 CA Arango-Davila (863_CR13) 2015; 125 MJ Burne (863_CR33) 2001; 70 L Liberale (863_CR142) 2018; 39 R Robert (863_CR194) 1992; 182 R Ross (863_CR195) 1976; 295 SA Loddick (863_CR151) 1996; 16 J Dong (863_CR60) 2007; 292 A Hanna (863_CR99) 2019; 6 S Goetze (863_CR86) 1999; 33 J Scheller (863_CR203) 2011; 1813 MB Carroll (863_CR39) 2018; 38 K Boniface (863_CR27) 2008; 226 BH Clausen (863_CR49) 2016; 6 K Gertz (863_CR84) 2012; 135 CR Trankle (863_CR234) 2018; 122 R Elhage (863_CR63) 1998; 97 OA Sobowale (863_CR215) 2016; 47 C Gebhard (863_CR81) 2009; 104 K Suzuki (863_CR221) 2001; 104 H Boutin (863_CR28) 2001; 21 P Akarasereenont (863_CR7) 1999; 8 N Maekawa (863_CR154) 2002; 39 L Liberale (863_CR140) 2020; 122 M Erta (863_CR69) 2012; 8 RM Friedlander (863_CR74) 1997; 185 C Koch (863_CR128) 2020; 98 H Noels (863_CR173) 2019; 39 JW Williams (863_CR243) 2019; 50 H Nawashiro (863_CR171) 1997; 778 G Ozen (863_CR177) 2020 DJ Angelini (863_CR11) 2006; 291 AK Anstensrud (863_CR12) 2019; 6 Q Feng (863_CR72) 2015; 9 L Branen (863_CR29) 2004; 24 H Ooboshi (863_CR175) 2005; 111 S Jovinge (863_CR114) 1996; 16 SA Schreyer (863_CR207) 1996; 271 SR Clark (863_CR46) 2008; 28 C Gao (863_CR76) 2020; 11 A Savard (863_CR202) 2015; 12 T Grewal (863_CR90) 2001; 21 VA Polunovsky (863_CR185) 1994; 214 L Tourneur (863_CR232) 2010; 31 JE Alard (863_CR8) 2015; 7 K Matsushita (863_CR157) 2005; 85 F de Bilbao (863_CR59) 2009; 110 M Swiatkowska (863_CR222) 2005; 272 MP Bevilacqua (863_CR22) 1984; 160 M Fuchs (863_CR75) 2003; 17 K Salmeron (863_CR199) 2016; 136 S Choi (863_CR44) 2018; 293 SA Loddick (863_CR152) 1997; 234 MG Works (863_CR245) 2013; 33 P Krishnamurthy (863_CR129) 2009; 104 A Abbate (863_CR2) 2011; 6 M Jung (863_CR115) 2017; 112 PR Lawler (863_CR133) 2020 P Dutta (863_CR62) 2012; 487 TX Zhao (863_CR252) 2020; 40 CA Davies (863_CR56) 1999; 19 SE Goldblum (863_CR87) 1993; 264 M Kamimura (863_CR116) 2005; 97 R Ramani (863_CR189) 2004; 287 BM Everett (863_CR70) 2019; 139 L Liberale (863_CR144) 2017; 24 SA Huber (863_CR106) 2001; 103 FR Rizzo (863_CR193) 2018; 2018 MR Lessard (863_CR136) 1988; 35 PM Madsen (863_CR153) 2016; 36 M Nash (863_CR169) 2019; 115 X Teng (863_CR223) 2002; 282 H Shimokawa (863_CR211) 1996; 97 H Nawashiro (863_CR170) 1997; 17 H Zhang (863_CR251) 2009; 29 J Pircher (863_CR184) 2012; 14 CJ Smith (863_CR213) 2018; 49 WH Newman (863_CR172) 2003; 109 F Labruto (863_CR131) 2005; 100 GW Moe (863_CR164) 2004; 287 B Viviani (863_CR238) 2003; 23 F Carbone (863_CR37) 2016; 22 WM Clark (863_CR47) 2000; 31 |
| References_xml | – volume: 66 start-page: 179 year: 2005 end-page: 185 ident: CR24 article-title: Tumor necrosis factor-alpha promotes atherosclerotic lesion progression in APOE*3-Leiden transgenic mice publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.01.001 – volume: 272 start-page: 19569 year: 1997 end-page: 19574 ident: CR206 article-title: Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta publication-title: J Biol Chem doi: 10.1074/jbc.272.31.19569 – volume: 86 start-page: 6753 year: 1989 end-page: 6757 ident: CR94 article-title: Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.86.17.6753 – volume: 17 start-page: 229 year: 1997 end-page: 232 ident: CR170 article-title: Inhibition of tumor necrosis factor and amelioration of brain infarction in mice publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199702000-00013 – year: 2019 ident: CR143 article-title: Interleukin-1beta mediates arterial thrombus formation via NET-associated tissue factor publication-title: J Clin Med doi: 10.3390/jcm8122072 – volume: 38 start-page: 1621 year: 2017 end-page: 1623 ident: CR34 article-title: Aging: the next cardiovascular disease? publication-title: Eur Heart J doi: 10.1093/eurheartj/ehx239 – volume: 566 start-page: 383 year: 2019 end-page: 387 ident: CR161 article-title: Sleep modulates haematopoiesis and protects against atherosclerosis publication-title: Nature doi: 10.1038/s41586-019-0948-2 – volume: 139 start-page: 1289 year: 2019 end-page: 1299 ident: CR70 article-title: Anti-inflammatory therapy with canakinumab for the prevention of hospitalization for heart failure publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.118.038010 – volume: 64 start-page: 1403 year: 2016 end-page: 1415 ident: CR205 article-title: IL-6 pathway in the liver: from physiopathology to therapy publication-title: J Hepatol doi: 10.1016/j.jhep.2016.02.004 – volume: 5 start-page: e11765 year: 2010 ident: CR188 article-title: Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation publication-title: PLoS ONE doi: 10.1371/journal.pone.0011765 – volume: 23 start-page: 8692 year: 2003 end-page: 8700 ident: CR238 article-title: Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-25-08692.2003 – year: 2020 ident: CR83 article-title: Roles of IL-1 in cancer: from tumor progression to resistance to targeted therapies publication-title: Int J Mol Sci doi: 10.3390/ijms21176009 – volume: 35 start-page: 567 year: 1988 end-page: 569 ident: CR136 article-title: A microbiological study of the contamination of the syringes used in anaesthesia practice publication-title: Can J Anaesth doi: 10.1007/BF03020341 – volume: 24 start-page: 1403 year: 2017 end-page: 1416 ident: CR144 article-title: Treatment with proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors to reduce cardiovascular inflammation and outcomes publication-title: Curr Med Chem doi: 10.2174/0929867324666170303123734 – volume: 18 start-page: 911 year: 2004 end-page: 913 ident: CR218 article-title: In vivo transfer of soluble TNF-alpha receptor 1 gene improves cardiac function and reduces infarct size after myocardial infarction in rats publication-title: FASEB J doi: 10.1096/fj.03-1148fje – volume: 126 start-page: 25 year: 2020 end-page: 37 ident: CR23 article-title: Rapamycin-loaded biomimetic nanoparticles reverse vascular inflammation publication-title: Circ Res doi: 10.1161/CIRCRESAHA.119.315185 – volume: 33 start-page: 183 year: 1999 end-page: 189 ident: CR86 article-title: TNF-alpha-induced migration of vascular smooth muscle cells is MAPK dependent publication-title: Hypertension doi: 10.1161/01.hyp.33.1.183 – volume: 115 start-page: 288 year: 2015 end-page: 292 ident: CR1 article-title: Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot studies) publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2014.11.003 – volume: 293 start-page: 14812 year: 2018 end-page: 14822 ident: CR44 article-title: TNF-alpha elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p-dependent down-regulation of cGMP-dependent kinase 1 publication-title: J Biol Chem doi: 10.1074/jbc.RA118.004220 – volume: 36 start-page: 92 year: 2015 end-page: 101 ident: CR158 article-title: Versatile functions for IL-6 in metabolism and cancer publication-title: Trends Immunol doi: 10.1016/j.it.2014.12.008 – year: 2020 ident: CR237 article-title: Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease publication-title: Haematologica doi: 10.3324/haematol.2020.252395 – volume: 8 start-page: 1039 year: 2019 ident: CR162 article-title: Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence publication-title: F1000Res doi: 10.12688/f1000research.19308.2 – volume: 66 start-page: 583 year: 2005 end-page: 593 ident: CR163 article-title: Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.01.008 – volume: 270 start-page: 9558 year: 1995 end-page: 9563 ident: CR240 article-title: Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms publication-title: J Biol Chem doi: 10.1074/jbc.270.16.9558 – year: 2020 ident: CR145 article-title: Inflammation and cardiovascular diseases: lessons from seminal clinical trials publication-title: Cardiovasc Res doi: 10.1093/cvr/cvaa211 – volume: 12 start-page: e0179065 year: 2017 ident: CR166 article-title: Proteome profiling in IL-1beta and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis publication-title: PLoS ONE doi: 10.1371/journal.pone.0179065 – volume: 138 start-page: 206 year: 1996 end-page: 213 ident: CR191 article-title: Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat publication-title: Exp Neurol doi: 10.1006/exnr.1996.0059 – volume: 12 start-page: 111 year: 2015 ident: CR202 article-title: Neuronal self-injury mediated by IL-1beta and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia publication-title: J Neuroinflamm doi: 10.1186/s12974-015-0330-8 – volume: 8 start-page: 287 year: 1999 end-page: 294 ident: CR7 article-title: The induction of cyclooxygenase-2 in IL-1beta-treated endothelial cells is inhibited by prostaglandin E2 through cAMP publication-title: Mediators Inflamm doi: 10.1080/09629359990298 – volume: 16 start-page: 932 year: 1996 end-page: 940 ident: CR151 article-title: Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199609000-00017 – volume: 11 start-page: 2622 year: 2020 ident: CR76 article-title: Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines publication-title: Nat Commun doi: 10.1038/s41467-020-16439-7 – volume: 166 start-page: 2674 year: 2001 end-page: 2680 ident: CR18 article-title: Il-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production publication-title: J Immunol doi: 10.4049/jimmunol.166.4.2674 – volume: 115 start-page: 713 year: 2019 end-page: 720 ident: CR169 article-title: Tumour necrosis factor superfamily members in ischaemic vascular diseases publication-title: Cardiovasc Res doi: 10.1093/cvr/cvz042 – volume: 101 start-page: 1019 year: 2000 end-page: 1026 ident: CR249 article-title: Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury publication-title: Circulation doi: 10.1161/01.cir.101.9.1019 – volume: 48 start-page: 320 year: 2006 end-page: 328 ident: CR93 article-title: Inhibition of TNF-alpha reduces myocardial injury and proinflammatory pathways following ischemia-reperfusion in the dog publication-title: J Cardiovasc Pharmacol doi: 10.1097/01.fjc.0000250079.46526.38 – volume: 284 start-page: H927 year: 2003 end-page: 930 ident: CR17 article-title: TNF-alpha antibodies are as effective as ischemic preconditioning in reducing infarct size in rabbits publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00374.2002 – volume: 388 start-page: 261 year: 2009 end-page: 265 ident: CR235 article-title: Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2009.07.152 – volume: 36 start-page: 596 year: 2016 end-page: 605 ident: CR160 article-title: A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X15606714 – volume: 29 start-page: 1319 year: 2009 end-page: 1330 ident: CR132 article-title: Microglia protect neurons against ischemia by synthesis of tumor necrosis factor publication-title: J Neurosci doi: 10.1523/JNEUROSCI.5505-08.2009 – volume: 6 start-page: 29291 year: 2016 ident: CR49 article-title: Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling publication-title: Sci Rep doi: 10.1038/srep29291 – volume: 36 start-page: 2877 year: 2015 end-page: 2884 ident: CR148 article-title: Inhibition of Tnf-alpha R1 signaling can rescue functional cortical plasticity impaired in early post-stroke period publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2015.06.015 – volume: 278 start-page: H1823 year: 2000 end-page: 1831 ident: CR201 article-title: Essential roles of IkappaB kinases alpha and beta in serum- and IL-1-induced human VSMC proliferation publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.2000.278.6.H1823 – volume: 21 start-page: 5528 year: 2001 end-page: 5534 ident: CR28 article-title: Role of IL-1alpha and IL-1beta in ischemic brain damage publication-title: J Neurosci doi: 10.1523/JNEUROSCI.21-15-05528.2001 – volume: 99 start-page: 69 year: 2006 end-page: 77 ident: CR180 article-title: Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome publication-title: Circ Res doi: 10.1161/01.RES.0000229685.37402.80 – volume: 75 start-page: 1305 year: 1990 end-page: 1310 ident: CR230 article-title: Interleukin-1 induces interleukin-6 production in peripheral blood monocytes publication-title: Blood doi: 10.1182/blood.V75.6.1305.1305 – volume: 142 start-page: 187 year: 2020 end-page: 189 ident: CR139 article-title: Postischemic administration of IL-1alpha neutralizing antibody reduces brain damage and neurological deficit in experimental stroke publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.120.046301 – volume: 122 start-page: 105735 year: 2020 ident: CR140 article-title: Statins reduce vascular inflammation in atherogenesis: a review of underlying molecular mechanisms publication-title: Int J Biochem Cell Biol doi: 10.1016/j.biocel.2020.105735 – volume: 28 start-page: 812 year: 2008 end-page: 819 ident: CR61 article-title: Role of smooth muscle cells in the initiation and early progression of atherosclerosis publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.107.159327 – volume: 19 start-page: 2364 year: 1999 end-page: 2367 ident: CR105 article-title: Interleukin-6 exacerbates early atherosclerosis in mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.19.10.2364 – volume: 111 start-page: 1 year: 2019 end-page: 5 ident: CR254 article-title: Recombinant human interleukin-1 receptor antagonist treatment protects rats from myocardial ischemia-reperfusion injury publication-title: Biomed Pharmacother doi: 10.1016/j.biopha.2018.12.031 – volume: 180 start-page: 11 year: 2005 end-page: 17 ident: CR174 article-title: Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient mice publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2004.11.016 – volume: 97 start-page: 769 year: 1996 end-page: 776 ident: CR211 article-title: Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor publication-title: J Clin Invest doi: 10.1172/JCI118476 – volume: 11 start-page: 203 year: 2014 ident: CR48 article-title: Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0203-6 – volume: 583 start-page: 127 year: 2020 end-page: 132 ident: CR10 article-title: Senolytic CAR T cells reverse senescence-associated pathologies publication-title: Nature doi: 10.1038/s41586-020-2403-9 – volume: 6 start-page: e001108 year: 2019 ident: CR12 article-title: Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI) publication-title: Open Heart doi: 10.1136/openhrt-2019-001108 – volume: 76 start-page: 1366 year: 2005 end-page: 1372 ident: CR66 article-title: A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.2004.054882 – volume: 100 start-page: 140 year: 2007 end-page: 146 ident: CR212 article-title: Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction publication-title: Circ Res doi: 10.1161/01.RES.0000255031.15793.86 – volume: 47 start-page: 498 year: 2016 end-page: 504 ident: CR150 article-title: Interleukin-4 is essential for microglia/macrophage M2 polarization and long-term recovery after cerebral ischemia publication-title: Stroke doi: 10.1161/STROKEAHA.115.012079 – volume: 19 start-page: 611 year: 1999 end-page: 616 ident: CR156 article-title: Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.19.3.611 – volume: 28 start-page: 387 year: 2008 end-page: 394 ident: CR46 article-title: Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations publication-title: J Cereb Blood Flow Metab doi: 10.1038/sj.jcbfm.9600537 – volume: 73 start-page: 215 year: 2019 end-page: 222 ident: CR226 article-title: The NLRP3 inflammasome inhibitor, OLT1177 (dapansutrile), reduces infarct size and preserves contractile function after ischemia reperfusion injury in the mouse publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000658 – volume: 109 start-page: 57 year: 2003 end-page: 61 ident: CR172 article-title: Cyclic AMP inhibits production of interleukin-6 and migration in human vascular smooth muscle cells publication-title: J Surg Res doi: 10.1016/s0022-4804(02)00038-0 – volume: 135 start-page: 1964 year: 2012 end-page: 1980 ident: CR84 article-title: Essential role of interleukin-6 in post-stroke angiogenesis publication-title: Brain doi: 10.1093/brain/aws075 – volume: 183 start-page: 87 year: 2017 end-page: 103 ident: CR197 article-title: Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation publication-title: Transl Res doi: 10.1016/j.trsl.2016.12.003 – volume: 6 start-page: 140 year: 2019 ident: CR99 article-title: The role of the TGF-beta superfamily in myocardial infarction publication-title: Front Cardiovasc Med doi: 10.3389/fcvm.2019.00140 – volume: 10 start-page: 150 year: 2017 end-page: 161 ident: CR53 article-title: CD4(+) Th2 cells are directly regulated by IL-10 during allergic airway inflammation publication-title: Mucosal Immunol doi: 10.1038/mi.2016.47 – volume: 37 start-page: 2079 year: 2017 end-page: 2085 ident: CR130 article-title: Tofacitinib improves atherosclerosis despite up-regulating serum cholesterol in patients with active rheumatoid arthritis: a cohort study publication-title: Rheumatol Int doi: 10.1007/s00296-017-3844-9 – volume: 107 start-page: 3133 year: 2003 end-page: 3140 ident: CR45 article-title: Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial publication-title: Circulation doi: 10.1161/01.CIR.0000077913.60364.D2 – volume: 182 start-page: 733 year: 1992 end-page: 739 ident: CR194 article-title: Interleukin-1 impairs both vascular contraction and relaxation in rabbit isolated aorta publication-title: Biochem Biophys Res Commun doi: 10.1016/0006-291x(92)91793-p – volume: 23 start-page: 1061 year: 2004 end-page: 1068 ident: CR20 article-title: Administration of a tumor necrosis factor inhibitor at the time of myocardial infarction attenuates subsequent ventricular remodeling publication-title: J Heart Lung Transplant doi: 10.1016/j.healun.2004.06.021 – volume: 22 start-page: 456 year: 2002 end-page: 461 ident: CR119 article-title: Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/hq0302.104905 – volume: 22 start-page: 5662 year: 2016 end-page: 5675 ident: CR37 article-title: Targeting inflammation in primary cardiovascular prevention publication-title: Curr Pharm Des doi: 10.2174/1381612822666160822124546 – volume: 4 start-page: 245 year: 2008 end-page: 255 ident: CR42 article-title: Role of reactive oxygen species in tumor necrosis factor-alpha induced endothelial dysfunction publication-title: Curr Hypertens Rev doi: 10.2174/157340208786241336 – volume: 4 start-page: 559 year: 2002 end-page: 561 ident: CR52 article-title: Clinical trials update: RENEWAL (RENAISSANCE and RECOVER) and ATTACH publication-title: Eur J Heart Fail doi: 10.1016/s1388-9842(02)00121-6 – volume: 122 start-page: 70 year: 2012 end-page: 79 ident: CR9 article-title: Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice publication-title: J Clin Invest doi: 10.1172/JCI43713 – volume: 17 start-page: 2118 year: 2003 end-page: 2120 ident: CR75 article-title: Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction publication-title: FASEB J doi: 10.1096/fj.03-0331fje – volume: 258 start-page: L57 year: 1990 end-page: 67 ident: CR88 article-title: Tumor necrosis factor-alpha augments pulmonary arterial transendothelial albumin flux in vitro publication-title: Am J Physiol doi: 10.1152/ajplung.1990.258.2.L57 – volume: 119 start-page: 1386 year: 2009 end-page: 1397 ident: CR98 article-title: Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kappaB and inflammatory activation publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.802918 – volume: 103 start-page: 2610 year: 2001 end-page: 2616 ident: CR106 article-title: T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia publication-title: Circulation doi: 10.1161/01.cir.103.21.2610 – volume: 74 start-page: 238 year: 2019 end-page: 256 ident: CR108 article-title: Cardiac MRI endpoints in myocardial infarction experimental and clinical trials: JACC scientific expert panel publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2019.05.024 – volume: 52 start-page: 890 year: 2012 end-page: 896 ident: CR124 article-title: Lessons from human coronary aspirate publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2011.06.022 – volume: 45 start-page: 153 year: 2005 end-page: 159 ident: CR250 article-title: Tumor necrosis factor alpha, rapid ventricular tachyarrhythmias, and infarct size in canine models of myocardial infarction publication-title: J Cardiovasc Pharmacol doi: 10.1097/01.fjc.0000151930.12026.b7 – volume: 10 start-page: 487 year: 2019 ident: CR41 article-title: Microglia-derived TNF-alpha mediates endothelial necroptosis aggravating blood brain-barrier disruption after ischemic stroke publication-title: Cell Death Dis doi: 10.1038/s41419-019-1716-9 – volume: 22 start-page: 437 year: 2008 end-page: 442 ident: CR231 article-title: A single intravenous sTNFR-Fc administration at the time of reperfusion limits infarct size–implications in reperfusion strategies in man publication-title: Cardiovasc Drugs Ther doi: 10.1007/s10557-008-6130-y – volume: 12 start-page: 12 year: 2013 ident: CR14 article-title: Coronary aspirate TNFalpha reflects saphenous vein bypass graft restenosis risk in diabetic patients publication-title: Cardiovasc Diabetol doi: 10.1186/1475-2840-12-12 – volume: 16 start-page: 49 year: 2011 end-page: 69 ident: CR125 article-title: TNFalpha in myocardial ischemia/reperfusion, remodeling and heart failure publication-title: Heart Fail Rev doi: 10.1007/s10741-010-9180-8 – volume: 115 start-page: 89 year: 1995 end-page: 98 ident: CR241 article-title: Interleukin-1 beta induces expression of adhesion molecules in human vascular smooth muscle cells and enhances adhesion of leukocytes to smooth muscle cells publication-title: Atherosclerosis doi: 10.1016/0021-9150(94)05503-b – volume: 1287 start-page: 47 year: 2009 end-page: 57 ident: CR224 article-title: Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected] publication-title: Brain Res doi: 10.1016/j.brainres.2009.06.081 – volume: 137 start-page: 1145 year: 1999 end-page: 1152 ident: CR137 article-title: Kinetics of tumor necrosis factor alpha in plasma and the cardioprotective effect of a monoclonal antibody to tumor necrosis factor alpha in acute myocardial infarction publication-title: Am Heart J doi: 10.1016/s0002-8703(99)70375-3 – volume: 99 start-page: 1330 year: 2013 end-page: 1335 ident: CR178 article-title: Cardiovascular effects of tumour necrosis factor alpha antagonism in patients with acute myocardial infarction: a first in human study publication-title: Heart doi: 10.1136/heartjnl-2013-303648 – volume: 356 start-page: 513 year: 2017 end-page: 519 ident: CR109 article-title: Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages publication-title: Science doi: 10.1126/science.aal3535 – volume: 15 start-page: 417 year: 1993 end-page: 422 ident: CR82 article-title: Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis publication-title: Dev Neurosci doi: 10.1159/000111367 – volume: 49 start-page: e949 issue: 943–957 year: 2018 ident: CR71 article-title: An interleukin-23-interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis publication-title: Immunity doi: 10.1016/j.immuni.2018.09.011 – volume: 214 start-page: 574 year: 2008 end-page: 583 ident: CR35 article-title: Progression of atherosclerosis in ApoE-deficient mice that express distinct molecular forms of TNF-alpha publication-title: J Pathol doi: 10.1002/path.2305 – volume: 195 start-page: e93 year: 2007 end-page: 99 ident: CR127 article-title: MRI follow-up of TNF-dependent differential progression of atherosclerotic wall-thickening in mouse aortic arch from early to advanced stages publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2007.06.015 – volume: 579 start-page: 18 year: 2014 end-page: 23 ident: CR147 article-title: Intracerebral interleukin-10 injection modulates post-ischemic neuroinflammation: an experimental microarray study publication-title: Neurosci Lett doi: 10.1016/j.neulet.2014.07.003 – volume: 24 start-page: 2137 year: 2004 end-page: 2142 ident: CR29 article-title: Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000143933.20616.1b – volume: 96 start-page: 239 year: 2009 end-page: 244 ident: CR246 article-title: Tumor necrosis factor-alpha deficiency retards early fatty-streak lesion by influencing the expression of inflammatory factors in apoE-null mice publication-title: Mol Genet Metab doi: 10.1016/j.ymgme.2008.11.166 – volume: 41 start-page: 757 year: 2009 end-page: 764 ident: CR149 article-title: Interleukin-1beta promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways publication-title: Exp Mol Med doi: 10.3858/emm.2009.41.10.082 – volume: 97 start-page: 305 year: 2005 end-page: 313 ident: CR116 article-title: Interleukin-10 suppresses tissue factor expression in lipopolysaccharide-stimulated macrophages via inhibition of Egr-1 and a serum response element/MEK-ERK1/2 pathway publication-title: Circ Res doi: 10.1161/01.RES.0000177893.24574.13 – volume: 163 start-page: 1117 year: 2003 end-page: 1125 ident: CR55 article-title: The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice publication-title: Am J Pathol doi: 10.1016/S0002-9440(10)63471-2 – volume: 19 start-page: 87 year: 1999 end-page: 98 ident: CR56 article-title: The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199901000-00010 – volume: 293 start-page: H743 year: 2007 end-page: 753 ident: CR167 article-title: Tumor necrosis factor-alpha is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00166.2007 – volume: 17 start-page: 1481 year: 2011 end-page: 1489 ident: CR64 article-title: Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells publication-title: Nat Med doi: 10.1038/nm.2513 – volume: 94 start-page: 459 year: 2005 end-page: 468 ident: CR247 article-title: Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons publication-title: J Neurochem doi: 10.1111/j.1471-4159.2005.03227.x – volume: 35 start-page: 1654 year: 2012 end-page: 1662 ident: CR40 article-title: Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes publication-title: Diabetes Care doi: 10.2337/dc11-2219 – volume: 36 start-page: 1681 year: 1993 end-page: 1690 ident: CR65 article-title: Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha publication-title: Arthritis Rheum doi: 10.1002/art.1780361206 – volume: 224 start-page: 454 year: 2010 end-page: 464 ident: CR134 article-title: TNF-alpha induces matrix metalloproteinase-9 expression in A549 cells: role of TNFR1/TRAF2/PKCalpha-dependent signaling pathways publication-title: J Cell Physiol doi: 10.1002/jcp.22142 – year: 2018 ident: CR67 article-title: IL-23R deficiency does not impact atherosclerotic plaque development in mice publication-title: J Am Heart Assoc doi: 10.1161/JAHA.117.008257 – volume: 377 start-page: 1119 year: 2017 end-page: 1131 ident: CR192 article-title: Antiinflammatory therapy with canakinumab for atherosclerotic disease publication-title: N Engl J Med doi: 10.1056/NEJMoa1707914 – volume: 2018 start-page: 8430123 year: 2018 ident: CR193 article-title: Tumor necrosis factor and interleukin-1beta modulate synaptic plasticity during neuroinflammation publication-title: Neural Plast doi: 10.1155/2018/8430123 – volume: 291 start-page: L1232 year: 2006 end-page: 1245 ident: CR11 article-title: TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia publication-title: Am J Physiol Lung Cell Mol Physiol doi: 10.1152/ajplung.00109.2006 – volume: 7 start-page: 317ra196 year: 2015 ident: CR8 article-title: Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5 publication-title: Sci Transl Med doi: 10.1126/scitranslmed.aad5330 – volume: 308 start-page: H1583 year: 2015 end-page: 1591 ident: CR77 article-title: TNF-alpha antagonism ameliorates myocardial ischemia-reperfusion injury in mice by upregulating adiponectin publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00346.2014 – volume: 6 start-page: e27923 year: 2011 ident: CR2 article-title: Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse publication-title: PLoS ONE doi: 10.1371/journal.pone.0027923 – volume: 160 start-page: 618 year: 1984 end-page: 623 ident: CR22 article-title: Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells publication-title: J Exp Med doi: 10.1084/jem.160.2.618 – volume: 49 start-page: 1210 year: 2018 end-page: 1216 ident: CR213 article-title: SCIL-STROKE (subcutaneous interleukin-1 receptor antagonist in ischemic stroke): a randomized controlled phase 2 trial publication-title: Stroke doi: 10.1161/STROKEAHA.118.020750 – volume: 41 start-page: 2974 year: 2020 end-page: 2982 ident: CR146 article-title: Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease publication-title: Eur Heart J doi: 10.1093/eurheartj/ehz961 – volume: 295 start-page: 369 year: 1976 end-page: 377 ident: CR195 article-title: The pathogenesis of atherosclerosis (first of two parts) publication-title: N Engl J Med doi: 10.1056/NEJM197608122950707 – volume: 117 start-page: 2670 year: 2008 end-page: 2683 ident: CR3 article-title: Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.107.740233 – volume: 32 start-page: 273 year: 2012 end-page: 280 ident: CR54 article-title: Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.111.229997 – volume: 103 start-page: 203 year: 2008 end-page: 211 ident: CR32 article-title: Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.178475 – volume: 38 start-page: 1546 year: 2001 end-page: 1553 ident: CR107 article-title: Neutralization of interleukin-1beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling publication-title: J Am Coll Cardiol doi: 10.1016/s0735-1097(01)01591-1 – volume: 5 start-page: 46 year: 2008 ident: CR50 article-title: Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice publication-title: J Neuroinflammation doi: 10.1186/1742-2094-5-46 – volume: 39 start-page: 3511 year: 2018 end-page: 3517 ident: CR142 article-title: Post-ischaemic administration of the murine Canakinumab-surrogate antibody improves outcome in experimental stroke publication-title: Eur Heart J doi: 10.1093/eurheartj/ehy286 – volume: 287 start-page: H1369 year: 2004 end-page: 1377 ident: CR189 article-title: Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00641.2003 – volume: 111 start-page: 913 year: 2005 end-page: 919 ident: CR175 article-title: Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia publication-title: Circulation doi: 10.1161/01.CIR.0000155622.68580.DC – volume: 98 start-page: 734 year: 2013 end-page: 745 ident: CR228 article-title: Interleukin-1beta blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse publication-title: Exp Physiol doi: 10.1113/expphysiol.2012.069831 – volume: 100 start-page: 198 year: 2005 end-page: 207 ident: CR131 article-title: Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia publication-title: Basic Res Cardiol doi: 10.1007/s00395-004-0509-0 – volume: 122 start-page: 1366 year: 2018 end-page: 1370 ident: CR234 article-title: Usefulness of canakinumab to improve exercise capacity in patients with long-term systolic heart failure and elevated C-reactive protein publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2018.07.002 – volume: 97 start-page: 242 year: 1998 end-page: 244 ident: CR63 article-title: Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice publication-title: Circulation doi: 10.1161/01.cir.97.3.242 – volume: 64 start-page: 1 year: 2014 end-page: 6 ident: CR227 article-title: Interleukin-1beta blockade improves left ventricular systolic/diastolic function and restores contractility reserve in severe ischemic cardiomyopathy in the mouse publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000106 – volume: 85 start-page: e17 year: 1999 end-page: 24 ident: CR155 article-title: Protective role of interleukin-10 in atherosclerosis publication-title: Circ Res doi: 10.1161/01.res.85.8.e17 – volume: 23 start-page: 573 year: 2009 end-page: 579 ident: CR217 article-title: IL-1/IL-1ra balance in the brain revisited—evidence from transgenic mouse models publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2009.02.015 – volume: 39 start-page: 1229 year: 2002 end-page: 1235 ident: CR154 article-title: Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha publication-title: J Am Coll Cardiol doi: 10.1016/s0735-1097(02)01738-2 – volume: 32 start-page: 1933 year: 2012 end-page: 1938 ident: CR219 article-title: Brain protection from stroke with intravenous TNFalpha decoy receptor-Trojan horse fusion protein publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2012.97 – volume: 29 start-page: 1164 year: 2009 end-page: 1171 ident: CR251 article-title: Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.109.187146 – volume: 38 start-page: 59 year: 2018 end-page: 66 ident: CR39 article-title: Short-term application of tocilizumab during myocardial infarction (STAT-MI) publication-title: Rheumatol Int doi: 10.1007/s00296-017-3842-y – volume: 292 start-page: C209 year: 2007 end-page: 215 ident: CR60 article-title: IL-1 and IL-6 induce hepatocyte plasminogen activator inhibitor-1 expression through independent signaling pathways converging on C/EBPdelta publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.00157.2006 – volume: 40 start-page: 853 year: 2020 end-page: 864 ident: CR252 article-title: 2019 ATVB plenary lecture: interleukin-2 therapy in cardiovascular disease: the potential to regulate innate and adaptive immunity publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.119.312287 – volume: 90 start-page: 1064 year: 2002 end-page: 1071 ident: CR183 article-title: Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes publication-title: Circ Res doi: 10.1161/01.res.0000018941.10726.fa – volume: 26 start-page: 273 year: 2012 end-page: 276 ident: CR229 article-title: Recombinant human interleukin-1 receptor antagonist provides cardioprotection during myocardial ischemia reperfusion in the mouse publication-title: Cardiovasc Drugs Ther doi: 10.1007/s10557-012-6389-x – volume: 16 start-page: 222 year: 2019 ident: CR200 article-title: Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke publication-title: J Neuroinflamm doi: 10.1186/s12974-019-1599-9 – volume: 45 start-page: 735 year: 2008 end-page: 741 ident: CR73 article-title: The role of TNF-alpha receptors p55 and p75 in acute myocardial ischemia/reperfusion injury and late preconditioning publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2008.08.014 – volume: 103 start-page: 591 year: 2008 end-page: 597 ident: CR248 article-title: Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.173963 – volume: 125 start-page: 936 year: 2015 end-page: 940 ident: CR13 article-title: Soluble or soluble/membrane TNF-alpha inhibitors protect the brain from focal ischemic injury in rats publication-title: Int J Neurosci doi: 10.3109/00207454.2014.980906 – volume: 226 start-page: 132 year: 2008 end-page: 146 ident: CR27 article-title: From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited publication-title: Immunol Rev doi: 10.1111/j.1600-065X.2008.00714.x – volume: 58 start-page: 1 year: 2020 end-page: 14 ident: CR36 article-title: Atherosclerosis in rheumatoid arthritis: promoters and opponents publication-title: Clin Rev Allergy Immunol doi: 10.1007/s12016-018-8714-z – volume: 18 start-page: 388 year: 2020 end-page: 400 ident: CR121 article-title: Muscle, bone, and fat crosstalk: the biological role of myokines, osteokines, and adipokines publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-020-00599-y – volume: 292 start-page: H2927 year: 2007 end-page: 2934 ident: CR208 article-title: Endogenous interleukin-1 alpha promotes a proliferative and proinflammatory phenotype in human vascular smooth muscle cells publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00700.2006 – volume: 23 start-page: 656 year: 2003 end-page: 660 ident: CR120 article-title: Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000064374.15232.C3 – volume: 214 start-page: 584 year: 1994 end-page: 594 ident: CR185 article-title: Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis publication-title: Exp Cell Res doi: 10.1006/excr.1994.1296 – volume: 67 start-page: 106 year: 2005 end-page: 115 ident: CR97 article-title: Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.02.016 – volume: 111 start-page: 1394 year: 2013 end-page: 1400 ident: CR5 article-title: Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study] publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2013.01.287 – volume: 112 start-page: 33 year: 2017 ident: CR115 article-title: IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation publication-title: Basic Res Cardiol doi: 10.1007/s00395-017-0622-5 – year: 2018 ident: CR242 article-title: Inflammation, autophagy, and apoptosis after myocardial infarction publication-title: J Am Heart Assoc doi: 10.1161/JAHA.117.008024 – volume: 2012 start-page: 737585 year: 2012 ident: CR92 article-title: Impact of an interleukin-1 receptor antagonist and erythropoietin on experimental myocardial ischemia/reperfusion injury publication-title: Sci World J doi: 10.1100/2012/737585 – volume: 16 start-page: 1573 year: 1996 end-page: 1579 ident: CR114 article-title: Human monocytes/macrophages release TNF-alpha in response to Ox-LDL publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.16.12.1573 – volume: 114 start-page: 30 year: 2019 ident: CR78 article-title: Relaxin mitigates microvascular damage and inflammation following cardiac ischemia-reperfusion publication-title: Basic Res Cardiol doi: 10.1007/s00395-019-0739-9 – volume: 2015 start-page: 759610 year: 2015 ident: CR122 article-title: Methotrexate, cyclosporine A, and biologics protect against atherosclerosis in rheumatoid arthritis publication-title: J Immunol Res doi: 10.1155/2015/759610 – volume: 131 start-page: 775 year: 2016 end-page: 791 ident: CR51 article-title: Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke publication-title: Acta Neuropathol doi: 10.1007/s00401-016-1541-5 – volume: 420 start-page: 868 year: 2002 end-page: 874 ident: CR138 article-title: Inflammation in atherosclerosis publication-title: Nature doi: 10.1038/nature01323 – volume: 755 start-page: 144900 year: 2020 ident: CR187 article-title: Circular RNA circ_0003645 silencing alleviates inflammation and apoptosis via the NF-kappaB pathway in endothelial cells induced by oxLDL publication-title: Gene doi: 10.1016/j.gene.2020.144900 – volume: 113 start-page: 965 year: 2013 end-page: 974 ident: CR80 article-title: Increased atherosclerotic lesion formation and vascular leukocyte accumulation in renal impairment are mediated by interleukin-17A publication-title: Circ Res doi: 10.1161/CIRCRESAHA.113.301934 – volume: 22 start-page: 38 year: 2002 end-page: 43 ident: CR233 article-title: Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor publication-title: J Neurosci doi: 10.1523/JNEUROSCI.22-01-00038.2002 – volume: 33 start-page: 1376 year: 2013 end-page: 1385 ident: CR245 article-title: Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.100 – volume: 778 start-page: 265 year: 1997 end-page: 271 ident: CR171 article-title: Neuroprotective effects of TNF binding protein in focal cerebral ischemia publication-title: Brain Res doi: 10.1016/s0006-8993(97)00981-5 – volume: 65 start-page: 489 year: 2016 end-page: 499 ident: CR113 article-title: Reduced acute myocardial ischemia-reperfusion injury in IL-6-deficient mice employing a closed-chest model publication-title: Inflamm Res doi: 10.1007/s00011-016-0931-4 – volume: 40 start-page: 28 year: 2013 end-page: 44 ident: CR112 article-title: Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation publication-title: J Autoimmun doi: 10.1016/j.jaut.2012.07.009 – volume: 2 start-page: 418 year: 2017 end-page: 430 ident: CR101 article-title: The IL-1beta antibody gevokizumab limits cardiac remodeling and coronary dysfunction in rats with heart failure publication-title: JACC Basic Transl Sci doi: 10.1016/j.jacbts.2017.06.005 – volume: 37 start-page: 2406 year: 2016 end-page: 2413 ident: CR126 article-title: Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial publication-title: Eur Heart J doi: 10.1093/eurheartj/ehw171 – volume: 31 start-page: e1904607 year: 2019 ident: CR95 article-title: Cyclodextrin-derived intrinsically bioactive nanoparticles for treatment of acute and chronic inflammatory diseases publication-title: Adv Mater doi: 10.1002/adma.201904607 – year: 2020 ident: CR177 article-title: The risk of cardiovascular events associated with disease-modifying antirheumatic drugs in rheumatoid arthritis publication-title: J Rheumatol doi: 10.3899/jrheum.200265 – volume: 25 start-page: 959 year: 2005 end-page: 967 ident: CR104 article-title: Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia publication-title: J Cereb Blood Flow Metab doi: 10.1038/sj.jcbfm.9600086 – volume: 272 start-page: 5821 year: 2005 end-page: 5831 ident: CR222 article-title: Induction of PAI-1 expression by tumor necrosis factor alpha in endothelial cells is mediated by its responsive element located in the 4G/5G site publication-title: FEBS J doi: 10.1111/j.1742-4658.2005.04979.x – volume: 9 start-page: 2173 year: 2019 ident: CR26 article-title: Tumour necrosis factor-alpha inhibition improves stroke outcome in a mouse model of rheumatoid arthritis publication-title: Sci Rep doi: 10.1038/s41598-019-38670-z – volume: 110 start-page: 3493 year: 2004 end-page: 3500 ident: CR204 article-title: Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis publication-title: Circulation doi: 10.1161/01.CIR.0000148135.08582.97 – volume: 106 start-page: 1992 year: 2005 end-page: 1994 ident: CR182 article-title: Tumor necrosis factor-alpha as trigger of platelet activation in patients with heart failure publication-title: Blood doi: 10.1182/blood-2005-03-1247 – volume: 31 start-page: 1715 year: 2000 end-page: 1720 ident: CR47 article-title: Lack of interleukin-6 expression is not protective against focal central nervous system ischemia publication-title: Stroke doi: 10.1161/01.str.31.7.1715 – volume: 25 start-page: 149 year: 2017 end-page: 157 ident: CR135 article-title: Intranasal administration of interleukin-1 receptor antagonist in a transient focal cerebral ischemia rat model publication-title: Biomol Ther (Seoul) doi: 10.4062/biomolther.2016.050 – volume: 136 start-page: 573 year: 2016 end-page: 580 ident: CR199 article-title: IL-1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury publication-title: J Neurochem doi: 10.1111/jnc.13422 – volume: 251 start-page: 189 year: 1998 end-page: 192 ident: CR216 article-title: IL-10 reduces rat brain injury following focal stroke publication-title: Neurosci Lett doi: 10.1016/s0304-3940(98)00537-0 – volume: 20 start-page: 117 year: 2018 ident: CR210 article-title: Tumor necrosis factor-alpha in heart failure: an updated review publication-title: Curr Cardiol Rep doi: 10.1007/s11886-018-1067-7 – volume: 31 start-page: 260 year: 2010 end-page: 269 ident: CR232 article-title: FADD: a regulator of life and death publication-title: Trends Immunol doi: 10.1016/j.it.2010.05.005 – volume: 104 start-page: I308 year: 2001 end-page: I303 ident: CR221 article-title: Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis publication-title: Circulation doi: 10.1161/hc37t1.094871 – volume: 85 start-page: 57 year: 2016 end-page: 65 ident: CR38 article-title: Vitamin D receptor is expressed within human carotid plaques and correlates with pro-inflammatory M1 macrophages publication-title: Vascul Pharmacol doi: 10.1016/j.vph.2016.08.004 – volume: 38 start-page: 505 year: 2005 end-page: 515 ident: CR96 article-title: IL-1beta and TNF-alpha upregulate angiotensin II type 1 (AT1) receptors on cardiac fibroblasts and are associated with increased AT1 density in the post-MI heart publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2004.12.015 – volume: 19 start-page: 274 year: 2012 end-page: 283 ident: CR190 article-title: TNF-alpha response of vascular endothelial and vascular smooth muscle cells involve differential utilization of ASK1 kinase and p73 publication-title: Cell Death Differ doi: 10.1038/cdd.2011.93 – volume: 9 start-page: e014941 year: 2020 ident: CR4 article-title: Interleukin-1 blockade inhibits the acute inflammatory response in patients with ST-segment-elevation myocardial infarction publication-title: J Am Heart Assoc doi: 10.1161/JAHA.119.014941 – volume: 117 start-page: 7 year: 2017 end-page: 18 ident: CR141 article-title: Pathophysiological relevance of macrophage subsets in atherogenesis publication-title: Thromb Haemost doi: 10.1160/TH16-08-0593 – volume: 14 start-page: R225 year: 2012 ident: CR184 article-title: Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2 publication-title: Arthritis Res Ther doi: 10.1186/ar4064 – volume: 50 start-page: 941 year: 2019 end-page: 954 ident: CR243 article-title: Cytokine circuits in cardiovascular disease publication-title: Immunity doi: 10.1016/j.immuni.2019.03.007 – volume: 147 start-page: 1477 year: 1995 end-page: 1486 ident: CR79 article-title: Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion publication-title: Am J Pathol – volume: 39 start-page: 583 year: 2019 end-page: 592 ident: CR173 article-title: Chemokines as therapeutic targets in cardiovascular disease publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.118.312037 – volume: 89 start-page: 247 year: 1991 end-page: 254 ident: CR198 article-title: Tumor necrosis factor-alpha in human arterial wall with atherosclerosis publication-title: Atherosclerosis doi: 10.1016/0021-9150(91)90066-c – volume: 90 start-page: 663 year: 2005 end-page: 670 ident: CR181 article-title: Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system publication-title: Exp Physiol doi: 10.1113/expphysiol.2005.030734 – volume: 85 start-page: 1210 year: 2005 end-page: 1223 ident: CR157 article-title: Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis publication-title: Lab Invest doi: 10.1038/labinvest.3700322 – volume: 8 start-page: 1254 year: 2012 end-page: 1266 ident: CR69 article-title: Interleukin-6, a major cytokine in the central nervous system publication-title: Int J Biol Sci doi: 10.7150/ijbs.4679 – volume: 40 start-page: 2482 year: 2019 end-page: 2491 ident: CR239 article-title: Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis publication-title: Eur Heart J doi: 10.1093/eurheartj/ehz008 – volume: 2015 start-page: 189292 year: 2015 ident: CR111 article-title: Effects of etanercept against transient cerebral ischemia in diabetic rats publication-title: Biomed Res Int doi: 10.1155/2015/189292 – volume: 234 start-page: 211 year: 1997 end-page: 215 ident: CR152 article-title: Endogenous interleukin-1 receptor antagonist is neuroprotective publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.1997.6436 – volume: 119 start-page: 1355 year: 2009 end-page: 1357 ident: CR209 article-title: Tumor necrosis factor-alpha and its receptors 1 and 2: Yin and Yang in myocardial infarction? publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.846105 – volume: 24 start-page: 1474 year: 2004 end-page: 1478 ident: CR186 article-title: Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000134378.86443.cd – volume: 118 start-page: 6 year: 2018 end-page: 27 ident: CR25 article-title: The pathophysiological role of neutrophil extracellular traps in inflammatory diseases publication-title: Thromb Haemost doi: 10.1160/TH17-09-0630 – volume: 33 start-page: 1955 year: 2013 end-page: 1966 ident: CR179 article-title: IL-10 deficiency exacerbates the brain inflammatory response to permanent ischemia without preventing resolution of the lesion publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.155 – volume: 287 start-page: H340 year: 2004 end-page: 350 ident: CR21 article-title: New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.01210.2003 – volume: 21 start-page: 825 year: 2001 end-page: 831 ident: CR90 article-title: Identification of a gamma-interferon-responsive element in the promoter of the human macrophage scavenger receptor A gene publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.21.5.825 – volume: 91 start-page: 566 year: 1995 end-page: 570 ident: CR176 article-title: Tumour necrosis factor alpha-induced oxidative burst in neutrophils adherent to fibronectin: effects of cyclic AMP-elevating agents publication-title: Br J Haematol doi: 10.1111/j.1365-2141.1995.tb05348.x – volume: 185 start-page: 933 year: 1997 end-page: 940 ident: CR74 article-title: Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury publication-title: J Exp Med doi: 10.1084/jem.185.5.933 – volume: 55 start-page: 117 year: 2010 end-page: 122 ident: CR236 article-title: Interleukin-1 trap attenuates cardiac remodeling after experimental acute myocardial infarction in mice publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0b013e3181c87e53 – volume: 94 start-page: 2007 year: 1997 end-page: 2012 ident: CR100 article-title: Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.94.5.2007 – volume: 21 start-page: 231 year: 2001 end-page: 240 ident: CR43 article-title: Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha publication-title: J Interferon Cytokine Res doi: 10.1089/107999001750169871 – volume: 110 start-page: 12 year: 2009 end-page: 22 ident: CR59 article-title: In vivo over-expression of interleukin-10 increases resistance to focal brain ischemia in mice publication-title: J Neurochem doi: 10.1111/j.1471-4159.2009.06098.x – volume: 186 start-page: 5489 year: 2011 end-page: 5496 ident: CR30 article-title: Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1beta-rich microparticles publication-title: J Immunol doi: 10.4049/jimmunol.1001623 – volume: 282 start-page: C144 year: 2002 end-page: 152 ident: CR223 article-title: Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cells publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.2002.282.1.C144 – volume: 104 start-page: 285 year: 2009 end-page: 294 ident: CR81 article-title: Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis publication-title: Basic Res Cardiol doi: 10.1007/s00395-008-0757-5 – volume: 173 start-page: 57 year: 2008 end-page: 67 ident: CR31 article-title: Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling publication-title: Am J Pathol doi: 10.2353/ajpath.2008.070974 – volume: 143 start-page: 4015 year: 1989 end-page: 4018 ident: CR103 article-title: Activated platelets express IL-1 activity publication-title: J Immunol – volume: 8 start-page: e3074 year: 2017 ident: CR220 article-title: NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension publication-title: Cell Death Dis doi: 10.1038/cddis.2017.470 – volume: 3 start-page: 315 year: 2014 end-page: 323 ident: CR118 article-title: Regenerative wound healing: the role of interleukin-10 publication-title: Adv Wound Care (New Rochelle) doi: 10.1089/wound.2013.0461 – volume: 37 start-page: 51 year: 2004 end-page: 61 ident: CR58 article-title: Tumor necrosis factor-alpha does not modulate ischemia/reperfusion injury in naive myocardium but is essential for the development of late preconditioning publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2004.03.012 – volume: 36 start-page: 1553 year: 2016 end-page: 1569 ident: CR153 article-title: Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X15610339 – volume: 74 start-page: 480 year: 2015 end-page: 489 ident: CR196 article-title: The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2014-206624 – volume: 271 start-page: 26174 year: 1996 end-page: 26178 ident: CR207 article-title: Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55 publication-title: J Biol Chem doi: 10.1074/jbc.271.42.26174 – volume: 83 start-page: 113 year: 1994 end-page: 118 ident: CR225 article-title: Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55 publication-title: Blood doi: 10.1182/blood.V83.1.113.113 – volume: 70 start-page: 192 year: 2001 end-page: 198 ident: CR33 article-title: IL-1 and TNF independent pathways mediate ICAM-1/VCAM-1 up-regulation in ischemia reperfusion injury publication-title: J Leukoc Biol – volume: 11 start-page: e0167195 year: 2016 ident: CR102 article-title: Inhibition of interleukin-6 receptor in a murine model of myocardial ischemia-reperfusion publication-title: PLoS ONE doi: 10.1371/journal.pone.0167195 – volume: 177 start-page: 25 year: 2020 end-page: 52 ident: CR15 article-title: Inflammatory biomarkers for cardiovascular risk stratification in familial hypercholesterolemia publication-title: Rev Physiol Biochem Pharmacol doi: 10.1007/112_2020_26 – volume: 28 start-page: 1233 year: 1997 end-page: 1244 ident: CR16 article-title: Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury publication-title: Stroke doi: 10.1161/01.str.28.6.1233 – volume: 98 start-page: 577 year: 2020 end-page: 585 ident: CR128 article-title: Functions of the CXCL12 receptor ACKR3/CXCR7-what has been perceived and what has been overlooked publication-title: Mol Pharmacol doi: 10.1124/molpharm.120.000056 – volume: 5 start-page: 196ra100 year: 2013 ident: CR85 article-title: Transforming growth factor-beta signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway publication-title: Sci Transl Med doi: 10.1126/scitranslmed.3006133 – year: 2019 ident: CR89 article-title: The therapeutic potential of nanoparticles to reduce inflammation in atherosclerosis publication-title: Biomolecules doi: 10.3390/biom9090416 – volume: 264 start-page: C894 year: 1993 end-page: 905 ident: CR87 article-title: TNF-alpha induces endothelial cell F-actin depolymerization, new actin synthesis, and barrier dysfunction publication-title: Am J Physiol doi: 10.1152/ajpcell.1993.264.4.C894 – volume: 104 start-page: e9 year: 2009 end-page: 18 ident: CR129 article-title: IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.188243 – volume: 3 start-page: 342 year: 2019 end-page: 355 ident: CR165 article-title: Nano-antagonist alleviates inflammation and allows for MRI of atherosclerosis publication-title: Nanotheranostics doi: 10.7150/ntno.37391 – volume: 1813 start-page: 878 year: 2011 end-page: 888 ident: CR203 article-title: The pro- and anti-inflammatory properties of the cytokine interleukin-6 publication-title: Biochim Biophys Acta doi: 10.1016/j.bbamcr.2011.01.034 – volume: 9 start-page: 1695 year: 2015 end-page: 1701 ident: CR72 article-title: Neuroprotective effect of interleukin-6 in a rat model of cerebral ischemia publication-title: Exp Ther Med doi: 10.3892/etm.2015.2363 – volume: 24 start-page: 1068 year: 2004 end-page: 1073 ident: CR110 article-title: Lack of interleukin-1 receptor antagonist modulates plaque composition in apolipoprotein E-deficient mice publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000127025.48140.a3 – volume: 69 start-page: 156 year: 2017 end-page: 160 ident: CR159 article-title: Reduction of myocardial ischemia-reperfusion injury by inhibiting interleukin-1 alpha publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000452 – volume: 172 start-page: 567 year: 2004 end-page: 576 ident: CR244 article-title: Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages publication-title: J Immunol doi: 10.4049/jimmunol.172.1.567 – volume: 20 start-page: 319 year: 2004 end-page: 325 ident: CR6 article-title: NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder publication-title: Immunity doi: 10.1016/s1074-7613(04)00046-9 – volume: 11 start-page: 109 year: 2012 end-page: 118 ident: CR57 article-title: TNF-alpha-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes publication-title: Cell Cycle doi: 10.4161/cc.11.1.18473 – year: 2020 ident: CR133 article-title: Targeting cardiovascular inflammation: next steps in clinical translation publication-title: Eur Heart J doi: 10.1093/eurheartj/ehaa099 – volume: 68 start-page: 493 year: 2005 end-page: 501 ident: CR168 article-title: Interleukin-1 receptor antagonist alters the response to vessel wall injury in a porcine coronary artery model publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.06.026 – volume: 385 start-page: 314 year: 2009 end-page: 318 ident: CR19 article-title: Influence of TNF-alpha and biomechanical stress on endothelial anti- and prothrombotic genes publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2009.05.046 – volume: 487 start-page: 325 year: 2012 end-page: 329 ident: CR62 article-title: Myocardial infarction accelerates atherosclerosis publication-title: Nature doi: 10.1038/nature11260 – volume: 287 start-page: H1813 year: 2004 end-page: 1820 ident: CR164 article-title: In vivo TNF-alpha inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00036.2004 – volume: 35 start-page: 11281 year: 2015 end-page: 11291 ident: CR253 article-title: Neuronal interleukin-4 as a modulator of microglial pathways and ischemic brain damage publication-title: J Neurosci doi: 10.1523/JNEUROSCI.1685-15.2015 – volume: 121 start-page: 1746 year: 2010 end-page: 1755 ident: CR214 article-title: Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.109.924886 – volume: 47 start-page: 2160 year: 2016 end-page: 2167 ident: CR215 article-title: Interleukin-1 in stroke: from bench to bedside publication-title: Stroke doi: 10.1161/STROKEAHA.115.010001 – volume: 108 start-page: 344 year: 2011 end-page: 352 ident: CR123 article-title: Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation publication-title: Circ Res doi: 10.1161/CIRCRESAHA.110.235713 – volume: 183 start-page: 8167 year: 2009 end-page: 8175 ident: CR68 article-title: Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice publication-title: J Immunol doi: 10.4049/jimmunol.0901126 – volume: 65 start-page: 296 year: 2017 end-page: 311 ident: CR91 article-title: Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2017.05.019 – year: 2019 ident: CR117 article-title: Cytokines in inflammatory disease publication-title: Int J Mol Sci doi: 10.3390/ijms20236008 – volume: 755 start-page: 144900 year: 2020 ident: 863_CR187 publication-title: Gene doi: 10.1016/j.gene.2020.144900 – volume: 11 start-page: e0167195 year: 2016 ident: 863_CR102 publication-title: PLoS ONE doi: 10.1371/journal.pone.0167195 – volume: 195 start-page: e93 year: 2007 ident: 863_CR127 publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2007.06.015 – volume: 214 start-page: 584 year: 1994 ident: 863_CR185 publication-title: Exp Cell Res doi: 10.1006/excr.1994.1296 – volume: 33 start-page: 1376 year: 2013 ident: 863_CR245 publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.100 – volume: 64 start-page: 1 year: 2014 ident: 863_CR227 publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000106 – volume: 183 start-page: 87 year: 2017 ident: 863_CR197 publication-title: Transl Res doi: 10.1016/j.trsl.2016.12.003 – volume: 39 start-page: 3511 year: 2018 ident: 863_CR142 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehy286 – volume: 292 start-page: H2927 year: 2007 ident: 863_CR208 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00700.2006 – volume: 8 start-page: 1039 year: 2019 ident: 863_CR162 publication-title: F1000Res doi: 10.12688/f1000research.19308.2 – year: 2020 ident: 863_CR133 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehaa099 – volume: 5 start-page: e11765 year: 2010 ident: 863_CR188 publication-title: PLoS ONE doi: 10.1371/journal.pone.0011765 – volume: 293 start-page: 14812 year: 2018 ident: 863_CR44 publication-title: J Biol Chem doi: 10.1074/jbc.RA118.004220 – volume: 65 start-page: 489 year: 2016 ident: 863_CR113 publication-title: Inflamm Res doi: 10.1007/s00011-016-0931-4 – volume: 287 start-page: H1813 year: 2004 ident: 863_CR164 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00036.2004 – volume: 69 start-page: 156 year: 2017 ident: 863_CR159 publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000452 – volume: 139 start-page: 1289 year: 2019 ident: 863_CR70 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.118.038010 – volume: 39 start-page: 1229 year: 2002 ident: 863_CR154 publication-title: J Am Coll Cardiol doi: 10.1016/s0735-1097(02)01738-2 – volume: 75 start-page: 1305 year: 1990 ident: 863_CR230 publication-title: Blood doi: 10.1182/blood.V75.6.1305.1305 – volume: 308 start-page: H1583 year: 2015 ident: 863_CR77 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00346.2014 – volume: 122 start-page: 105735 year: 2020 ident: 863_CR140 publication-title: Int J Biochem Cell Biol doi: 10.1016/j.biocel.2020.105735 – volume: 104 start-page: I308 year: 2001 ident: 863_CR221 publication-title: Circulation doi: 10.1161/hc37t1.094871 – volume: 282 start-page: C144 year: 2002 ident: 863_CR223 publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.2002.282.1.C144 – volume: 66 start-page: 179 year: 2005 ident: 863_CR24 publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.01.001 – volume: 377 start-page: 1119 year: 2017 ident: 863_CR192 publication-title: N Engl J Med doi: 10.1056/NEJMoa1707914 – volume: 83 start-page: 113 year: 1994 ident: 863_CR225 publication-title: Blood doi: 10.1182/blood.V83.1.113.113 – volume: 126 start-page: 25 year: 2020 ident: 863_CR23 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.119.315185 – volume: 12 start-page: e0179065 year: 2017 ident: 863_CR166 publication-title: PLoS ONE doi: 10.1371/journal.pone.0179065 – volume: 106 start-page: 1992 year: 2005 ident: 863_CR182 publication-title: Blood doi: 10.1182/blood-2005-03-1247 – volume: 166 start-page: 2674 year: 2001 ident: 863_CR18 publication-title: J Immunol doi: 10.4049/jimmunol.166.4.2674 – volume: 487 start-page: 325 year: 2012 ident: 863_CR62 publication-title: Nature doi: 10.1038/nature11260 – volume: 113 start-page: 965 year: 2013 ident: 863_CR80 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.113.301934 – volume: 29 start-page: 1164 year: 2009 ident: 863_CR251 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.109.187146 – volume: 287 start-page: H1369 year: 2004 ident: 863_CR189 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00641.2003 – volume: 385 start-page: 314 year: 2009 ident: 863_CR19 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2009.05.046 – volume: 224 start-page: 454 year: 2010 ident: 863_CR134 publication-title: J Cell Physiol doi: 10.1002/jcp.22142 – year: 2018 ident: 863_CR242 publication-title: J Am Heart Assoc doi: 10.1161/JAHA.117.008024 – volume: 172 start-page: 567 year: 2004 ident: 863_CR244 publication-title: J Immunol doi: 10.4049/jimmunol.172.1.567 – volume: 85 start-page: 1210 year: 2005 ident: 863_CR157 publication-title: Lab Invest doi: 10.1038/labinvest.3700322 – volume: 12 start-page: 111 year: 2015 ident: 863_CR202 publication-title: J Neuroinflamm doi: 10.1186/s12974-015-0330-8 – volume: 16 start-page: 222 year: 2019 ident: 863_CR200 publication-title: J Neuroinflamm doi: 10.1186/s12974-019-1599-9 – volume: 2012 start-page: 737585 year: 2012 ident: 863_CR92 publication-title: Sci World J doi: 10.1100/2012/737585 – volume: 31 start-page: e1904607 year: 2019 ident: 863_CR95 publication-title: Adv Mater doi: 10.1002/adma.201904607 – volume: 2015 start-page: 759610 year: 2015 ident: 863_CR122 publication-title: J Immunol Res doi: 10.1155/2015/759610 – volume: 24 start-page: 2137 year: 2004 ident: 863_CR29 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000143933.20616.1b – volume: 6 start-page: e27923 year: 2011 ident: 863_CR2 publication-title: PLoS ONE doi: 10.1371/journal.pone.0027923 – year: 2019 ident: 863_CR117 publication-title: Int J Mol Sci doi: 10.3390/ijms20236008 – volume: 38 start-page: 1546 year: 2001 ident: 863_CR107 publication-title: J Am Coll Cardiol doi: 10.1016/s0735-1097(01)01591-1 – volume: 89 start-page: 247 year: 1991 ident: 863_CR198 publication-title: Atherosclerosis doi: 10.1016/0021-9150(91)90066-c – year: 2020 ident: 863_CR237 publication-title: Haematologica doi: 10.3324/haematol.2020.252395 – volume: 28 start-page: 812 year: 2008 ident: 863_CR61 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.107.159327 – volume: 17 start-page: 229 year: 1997 ident: 863_CR170 publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199702000-00013 – volume: 388 start-page: 261 year: 2009 ident: 863_CR235 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2009.07.152 – volume: 109 start-page: 57 year: 2003 ident: 863_CR172 publication-title: J Surg Res doi: 10.1016/s0022-4804(02)00038-0 – volume: 26 start-page: 273 year: 2012 ident: 863_CR229 publication-title: Cardiovasc Drugs Ther doi: 10.1007/s10557-012-6389-x – volume: 1287 start-page: 47 year: 2009 ident: 863_CR224 publication-title: Brain Res doi: 10.1016/j.brainres.2009.06.081 – volume: 278 start-page: H1823 year: 2000 ident: 863_CR201 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.2000.278.6.H1823 – volume: 11 start-page: 203 year: 2014 ident: 863_CR48 publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0203-6 – volume: 291 start-page: L1232 year: 2006 ident: 863_CR11 publication-title: Am J Physiol Lung Cell Mol Physiol doi: 10.1152/ajplung.00109.2006 – volume: 19 start-page: 87 year: 1999 ident: 863_CR56 publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199901000-00010 – volume: 70 start-page: 192 year: 2001 ident: 863_CR33 publication-title: J Leukoc Biol doi: 10.1189/jlb.70.2.192 – volume: 6 start-page: 140 year: 2019 ident: 863_CR99 publication-title: Front Cardiovasc Med doi: 10.3389/fcvm.2019.00140 – volume: 103 start-page: 2610 year: 2001 ident: 863_CR106 publication-title: Circulation doi: 10.1161/01.cir.103.21.2610 – volume: 2015 start-page: 189292 year: 2015 ident: 863_CR111 publication-title: Biomed Res Int doi: 10.1155/2015/189292 – volume: 122 start-page: 70 year: 2012 ident: 863_CR9 publication-title: J Clin Invest doi: 10.1172/JCI43713 – volume: 356 start-page: 513 year: 2017 ident: 863_CR109 publication-title: Science doi: 10.1126/science.aal3535 – volume: 45 start-page: 735 year: 2008 ident: 863_CR73 publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2008.08.014 – volume: 104 start-page: 285 year: 2009 ident: 863_CR81 publication-title: Basic Res Cardiol doi: 10.1007/s00395-008-0757-5 – volume: 284 start-page: H927 year: 2003 ident: 863_CR17 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00374.2002 – volume: 163 start-page: 1117 year: 2003 ident: 863_CR55 publication-title: Am J Pathol doi: 10.1016/S0002-9440(10)63471-2 – volume: 98 start-page: 577 year: 2020 ident: 863_CR128 publication-title: Mol Pharmacol doi: 10.1124/molpharm.120.000056 – volume: 38 start-page: 59 year: 2018 ident: 863_CR39 publication-title: Rheumatol Int doi: 10.1007/s00296-017-3842-y – volume: 49 start-page: e949 issue: 943–957 year: 2018 ident: 863_CR71 publication-title: Immunity doi: 10.1016/j.immuni.2018.09.011 – volume: 185 start-page: 933 year: 1997 ident: 863_CR74 publication-title: J Exp Med doi: 10.1084/jem.185.5.933 – volume: 55 start-page: 117 year: 2010 ident: 863_CR236 publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0b013e3181c87e53 – volume: 31 start-page: 1715 year: 2000 ident: 863_CR47 publication-title: Stroke doi: 10.1161/01.str.31.7.1715 – volume: 115 start-page: 713 year: 2019 ident: 863_CR169 publication-title: Cardiovasc Res doi: 10.1093/cvr/cvz042 – volume: 137 start-page: 1145 year: 1999 ident: 863_CR137 publication-title: Am Heart J doi: 10.1016/s0002-8703(99)70375-3 – volume: 38 start-page: 505 year: 2005 ident: 863_CR96 publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2004.12.015 – volume: 35 start-page: 11281 year: 2015 ident: 863_CR253 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.1685-15.2015 – volume: 107 start-page: 3133 year: 2003 ident: 863_CR45 publication-title: Circulation doi: 10.1161/01.CIR.0000077913.60364.D2 – volume: 65 start-page: 296 year: 2017 ident: 863_CR91 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2017.05.019 – volume: 37 start-page: 2079 year: 2017 ident: 863_CR130 publication-title: Rheumatol Int doi: 10.1007/s00296-017-3844-9 – volume: 579 start-page: 18 year: 2014 ident: 863_CR147 publication-title: Neurosci Lett doi: 10.1016/j.neulet.2014.07.003 – volume: 122 start-page: 1366 year: 2018 ident: 863_CR234 publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2018.07.002 – volume: 272 start-page: 19569 year: 1997 ident: 863_CR206 publication-title: J Biol Chem doi: 10.1074/jbc.272.31.19569 – volume: 226 start-page: 132 year: 2008 ident: 863_CR27 publication-title: Immunol Rev doi: 10.1111/j.1600-065X.2008.00714.x – volume: 35 start-page: 567 year: 1988 ident: 863_CR136 publication-title: Can J Anaesth doi: 10.1007/BF03020341 – volume: 111 start-page: 913 year: 2005 ident: 863_CR175 publication-title: Circulation doi: 10.1161/01.CIR.0000155622.68580.DC – volume: 16 start-page: 932 year: 1996 ident: 863_CR151 publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-199609000-00017 – volume: 119 start-page: 1355 year: 2009 ident: 863_CR209 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.846105 – volume: 85 start-page: e17 year: 1999 ident: 863_CR155 publication-title: Circ Res doi: 10.1161/01.res.85.8.e17 – volume: 119 start-page: 1386 year: 2009 ident: 863_CR98 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.802918 – volume: 50 start-page: 941 year: 2019 ident: 863_CR243 publication-title: Immunity doi: 10.1016/j.immuni.2019.03.007 – volume: 114 start-page: 30 year: 2019 ident: 863_CR78 publication-title: Basic Res Cardiol doi: 10.1007/s00395-019-0739-9 – volume: 138 start-page: 206 year: 1996 ident: 863_CR191 publication-title: Exp Neurol doi: 10.1006/exnr.1996.0059 – volume: 36 start-page: 92 year: 2015 ident: 863_CR158 publication-title: Trends Immunol doi: 10.1016/j.it.2014.12.008 – volume: 15 start-page: 417 year: 1993 ident: 863_CR82 publication-title: Dev Neurosci doi: 10.1159/000111367 – volume: 32 start-page: 273 year: 2012 ident: 863_CR54 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.111.229997 – volume: 5 start-page: 196ra100 year: 2013 ident: 863_CR85 publication-title: Sci Transl Med doi: 10.1126/scitranslmed.3006133 – volume: 566 start-page: 383 year: 2019 ident: 863_CR161 publication-title: Nature doi: 10.1038/s41586-019-0948-2 – volume: 420 start-page: 868 year: 2002 ident: 863_CR138 publication-title: Nature doi: 10.1038/nature01323 – year: 2020 ident: 863_CR145 publication-title: Cardiovasc Res doi: 10.1093/cvr/cvaa211 – volume: 94 start-page: 2007 year: 1997 ident: 863_CR100 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.94.5.2007 – volume: 99 start-page: 1330 year: 2013 ident: 863_CR178 publication-title: Heart doi: 10.1136/heartjnl-2013-303648 – volume: 36 start-page: 1681 year: 1993 ident: 863_CR65 publication-title: Arthritis Rheum doi: 10.1002/art.1780361206 – volume: 14 start-page: R225 year: 2012 ident: 863_CR184 publication-title: Arthritis Res Ther doi: 10.1186/ar4064 – volume: 19 start-page: 611 year: 1999 ident: 863_CR156 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.19.3.611 – volume: 37 start-page: 51 year: 2004 ident: 863_CR58 publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2004.03.012 – volume: 17 start-page: 2118 year: 2003 ident: 863_CR75 publication-title: FASEB J doi: 10.1096/fj.03-0331fje – volume: 147 start-page: 1477 year: 1995 ident: 863_CR79 publication-title: Am J Pathol – volume: 23 start-page: 656 year: 2003 ident: 863_CR120 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000064374.15232.C3 – year: 2020 ident: 863_CR83 publication-title: Int J Mol Sci doi: 10.3390/ijms21176009 – volume: 31 start-page: 260 year: 2010 ident: 863_CR232 publication-title: Trends Immunol doi: 10.1016/j.it.2010.05.005 – volume: 41 start-page: 757 year: 2009 ident: 863_CR149 publication-title: Exp Mol Med doi: 10.3858/emm.2009.41.10.082 – volume: 47 start-page: 498 year: 2016 ident: 863_CR150 publication-title: Stroke doi: 10.1161/STROKEAHA.115.012079 – volume: 64 start-page: 1403 year: 2016 ident: 863_CR205 publication-title: J Hepatol doi: 10.1016/j.jhep.2016.02.004 – volume: 142 start-page: 187 year: 2020 ident: 863_CR139 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.120.046301 – volume: 9 start-page: 1695 year: 2015 ident: 863_CR72 publication-title: Exp Ther Med doi: 10.3892/etm.2015.2363 – volume: 17 start-page: 1481 year: 2011 ident: 863_CR64 publication-title: Nat Med doi: 10.1038/nm.2513 – volume: 6 start-page: e001108 year: 2019 ident: 863_CR12 publication-title: Open Heart doi: 10.1136/openhrt-2019-001108 – volume: 36 start-page: 2877 year: 2015 ident: 863_CR148 publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2015.06.015 – volume: 143 start-page: 4015 year: 1989 ident: 863_CR103 publication-title: J Immunol doi: 10.4049/jimmunol.143.12.4015 – volume: 86 start-page: 6753 year: 1989 ident: 863_CR94 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.86.17.6753 – volume: 97 start-page: 305 year: 2005 ident: 863_CR116 publication-title: Circ Res doi: 10.1161/01.RES.0000177893.24574.13 – volume: 40 start-page: 2482 year: 2019 ident: 863_CR239 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehz008 – volume: 25 start-page: 149 year: 2017 ident: 863_CR135 publication-title: Biomol Ther (Seoul) doi: 10.4062/biomolther.2016.050 – volume: 115 start-page: 89 year: 1995 ident: 863_CR241 publication-title: Atherosclerosis doi: 10.1016/0021-9150(94)05503-b – volume: 295 start-page: 369 year: 1976 ident: 863_CR195 publication-title: N Engl J Med doi: 10.1056/NEJM197608122950707 – volume: 24 start-page: 1403 year: 2017 ident: 863_CR144 publication-title: Curr Med Chem doi: 10.2174/0929867324666170303123734 – volume: 73 start-page: 215 year: 2019 ident: 863_CR226 publication-title: J Cardiovasc Pharmacol doi: 10.1097/FJC.0000000000000658 – volume: 214 start-page: 574 year: 2008 ident: 863_CR35 publication-title: J Pathol doi: 10.1002/path.2305 – volume: 33 start-page: 183 year: 1999 ident: 863_CR86 publication-title: Hypertension doi: 10.1161/01.hyp.33.1.183 – volume: 23 start-page: 573 year: 2009 ident: 863_CR217 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2009.02.015 – volume: 118 start-page: 6 year: 2018 ident: 863_CR25 publication-title: Thromb Haemost doi: 10.1160/TH17-09-0630 – volume: 49 start-page: 1210 year: 2018 ident: 863_CR213 publication-title: Stroke doi: 10.1161/STROKEAHA.118.020750 – volume: 12 start-page: 12 year: 2013 ident: 863_CR14 publication-title: Cardiovasc Diabetol doi: 10.1186/1475-2840-12-12 – volume: 272 start-page: 5821 year: 2005 ident: 863_CR222 publication-title: FEBS J doi: 10.1111/j.1742-4658.2005.04979.x – volume: 98 start-page: 734 year: 2013 ident: 863_CR228 publication-title: Exp Physiol doi: 10.1113/expphysiol.2012.069831 – volume: 3 start-page: 315 year: 2014 ident: 863_CR118 publication-title: Adv Wound Care (New Rochelle) doi: 10.1089/wound.2013.0461 – volume: 40 start-page: 28 year: 2013 ident: 863_CR112 publication-title: J Autoimmun doi: 10.1016/j.jaut.2012.07.009 – volume: 33 start-page: 1955 year: 2013 ident: 863_CR179 publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.155 – volume: 22 start-page: 38 year: 2002 ident: 863_CR233 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.22-01-00038.2002 – volume: 9 start-page: e014941 year: 2020 ident: 863_CR4 publication-title: J Am Heart Assoc doi: 10.1161/JAHA.119.014941 – volume: 103 start-page: 203 year: 2008 ident: 863_CR32 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.178475 – volume: 90 start-page: 663 year: 2005 ident: 863_CR181 publication-title: Exp Physiol doi: 10.1113/expphysiol.2005.030734 – volume: 28 start-page: 1233 year: 1997 ident: 863_CR16 publication-title: Stroke doi: 10.1161/01.str.28.6.1233 – volume: 121 start-page: 1746 year: 2010 ident: 863_CR214 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.109.924886 – volume: 264 start-page: C894 year: 1993 ident: 863_CR87 publication-title: Am J Physiol doi: 10.1152/ajpcell.1993.264.4.C894 – volume: 90 start-page: 1064 year: 2002 ident: 863_CR183 publication-title: Circ Res doi: 10.1161/01.res.0000018941.10726.fa – volume: 24 start-page: 1068 year: 2004 ident: 863_CR110 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000127025.48140.a3 – volume: 22 start-page: 437 year: 2008 ident: 863_CR231 publication-title: Cardiovasc Drugs Ther doi: 10.1007/s10557-008-6130-y – volume: 108 start-page: 344 year: 2011 ident: 863_CR123 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.110.235713 – volume: 16 start-page: 1573 year: 1996 ident: 863_CR114 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.16.12.1573 – volume: 20 start-page: 117 year: 2018 ident: 863_CR210 publication-title: Curr Cardiol Rep doi: 10.1007/s11886-018-1067-7 – volume: 131 start-page: 775 year: 2016 ident: 863_CR51 publication-title: Acta Neuropathol doi: 10.1007/s00401-016-1541-5 – volume: 8 start-page: 1254 year: 2012 ident: 863_CR69 publication-title: Int J Biol Sci doi: 10.7150/ijbs.4679 – year: 2019 ident: 863_CR143 publication-title: J Clin Med doi: 10.3390/jcm8122072 – volume: 270 start-page: 9558 year: 1995 ident: 863_CR240 publication-title: J Biol Chem doi: 10.1074/jbc.270.16.9558 – volume: 19 start-page: 2364 year: 1999 ident: 863_CR105 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.19.10.2364 – volume: 94 start-page: 459 year: 2005 ident: 863_CR247 publication-title: J Neurochem doi: 10.1111/j.1471-4159.2005.03227.x – volume: 4 start-page: 559 year: 2002 ident: 863_CR52 publication-title: Eur J Heart Fail doi: 10.1016/s1388-9842(02)00121-6 – volume: 21 start-page: 5528 year: 2001 ident: 863_CR28 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.21-15-05528.2001 – volume: 22 start-page: 5662 year: 2016 ident: 863_CR37 publication-title: Curr Pharm Des doi: 10.2174/1381612822666160822124546 – volume: 52 start-page: 890 year: 2012 ident: 863_CR124 publication-title: J Mol Cell Cardiol doi: 10.1016/j.yjmcc.2011.06.022 – volume: 45 start-page: 153 year: 2005 ident: 863_CR250 publication-title: J Cardiovasc Pharmacol doi: 10.1097/01.fjc.0000151930.12026.b7 – volume: 287 start-page: H340 year: 2004 ident: 863_CR21 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.01210.2003 – volume: 40 start-page: 853 year: 2020 ident: 863_CR252 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.119.312287 – volume: 68 start-page: 493 year: 2005 ident: 863_CR168 publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.06.026 – volume: 19 start-page: 274 year: 2012 ident: 863_CR190 publication-title: Cell Death Differ doi: 10.1038/cdd.2011.93 – volume: 101 start-page: 1019 year: 2000 ident: 863_CR249 publication-title: Circulation doi: 10.1161/01.cir.101.9.1019 – volume: 100 start-page: 198 year: 2005 ident: 863_CR131 publication-title: Basic Res Cardiol doi: 10.1007/s00395-004-0509-0 – volume: 778 start-page: 265 year: 1997 ident: 863_CR171 publication-title: Brain Res doi: 10.1016/s0006-8993(97)00981-5 – volume: 24 start-page: 1474 year: 2004 ident: 863_CR186 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000134378.86443.cd – volume: 97 start-page: 242 year: 1998 ident: 863_CR63 publication-title: Circulation doi: 10.1161/01.cir.97.3.242 – volume: 21 start-page: 825 year: 2001 ident: 863_CR90 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.atv.21.5.825 – volume: 23 start-page: 1061 year: 2004 ident: 863_CR20 publication-title: J Heart Lung Transplant doi: 10.1016/j.healun.2004.06.021 – volume: 76 start-page: 1366 year: 2005 ident: 863_CR66 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.2004.054882 – volume: 103 start-page: 591 year: 2008 ident: 863_CR248 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.173963 – volume: 66 start-page: 583 year: 2005 ident: 863_CR163 publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.01.008 – volume: 7 start-page: 317ra196 year: 2015 ident: 863_CR8 publication-title: Sci Transl Med doi: 10.1126/scitranslmed.aad5330 – volume: 21 start-page: 231 year: 2001 ident: 863_CR43 publication-title: J Interferon Cytokine Res doi: 10.1089/107999001750169871 – volume: 67 start-page: 106 year: 2005 ident: 863_CR97 publication-title: Cardiovasc Res doi: 10.1016/j.cardiores.2005.02.016 – volume: 97 start-page: 769 year: 1996 ident: 863_CR211 publication-title: J Clin Invest doi: 10.1172/JCI118476 – volume: 74 start-page: 238 year: 2019 ident: 863_CR108 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2019.05.024 – volume: 48 start-page: 320 year: 2006 ident: 863_CR93 publication-title: J Cardiovasc Pharmacol doi: 10.1097/01.fjc.0000250079.46526.38 – volume: 96 start-page: 239 year: 2009 ident: 863_CR246 publication-title: Mol Genet Metab doi: 10.1016/j.ymgme.2008.11.166 – volume: 35 start-page: 1654 year: 2012 ident: 863_CR40 publication-title: Diabetes Care doi: 10.2337/dc11-2219 – volume: 36 start-page: 1553 year: 2016 ident: 863_CR153 publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X15610339 – volume: 173 start-page: 57 year: 2008 ident: 863_CR31 publication-title: Am J Pathol doi: 10.2353/ajpath.2008.070974 – volume: 41 start-page: 2974 year: 2020 ident: 863_CR146 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehz961 – volume: 110 start-page: 3493 year: 2004 ident: 863_CR204 publication-title: Circulation doi: 10.1161/01.CIR.0000148135.08582.97 – volume: 85 start-page: 57 year: 2016 ident: 863_CR38 publication-title: Vascul Pharmacol doi: 10.1016/j.vph.2016.08.004 – volume: 11 start-page: 2622 year: 2020 ident: 863_CR76 publication-title: Nat Commun doi: 10.1038/s41467-020-16439-7 – volume: 104 start-page: e9 year: 2009 ident: 863_CR129 publication-title: Circ Res doi: 10.1161/CIRCRESAHA.108.188243 – volume: 258 start-page: L57 year: 1990 ident: 863_CR88 publication-title: Am J Physiol doi: 10.1152/ajplung.1990.258.2.L57 – volume: 117 start-page: 7 year: 2017 ident: 863_CR141 publication-title: Thromb Haemost doi: 10.1160/TH16-08-0593 – volume: 10 start-page: 487 year: 2019 ident: 863_CR41 publication-title: Cell Death Dis doi: 10.1038/s41419-019-1716-9 – volume: 1813 start-page: 878 year: 2011 ident: 863_CR203 publication-title: Biochim Biophys Acta doi: 10.1016/j.bbamcr.2011.01.034 – volume: 6 start-page: 29291 year: 2016 ident: 863_CR49 publication-title: Sci Rep doi: 10.1038/srep29291 – year: 2019 ident: 863_CR89 publication-title: Biomolecules doi: 10.3390/biom9090416 – volume: 74 start-page: 480 year: 2015 ident: 863_CR196 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2014-206624 – volume: 135 start-page: 1964 year: 2012 ident: 863_CR84 publication-title: Brain doi: 10.1093/brain/aws075 – volume: 183 start-page: 8167 year: 2009 ident: 863_CR68 publication-title: J Immunol doi: 10.4049/jimmunol.0901126 – volume: 18 start-page: 388 year: 2020 ident: 863_CR121 publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-020-00599-y – volume: 234 start-page: 211 year: 1997 ident: 863_CR152 publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.1997.6436 – year: 2018 ident: 863_CR67 publication-title: J Am Heart Assoc doi: 10.1161/JAHA.117.008257 – volume: 29 start-page: 1319 year: 2009 ident: 863_CR132 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.5505-08.2009 – volume: 16 start-page: 49 year: 2011 ident: 863_CR125 publication-title: Heart Fail Rev doi: 10.1007/s10741-010-9180-8 – volume: 8 start-page: 287 year: 1999 ident: 863_CR7 publication-title: Mediators Inflamm doi: 10.1080/09629359990298 – volume: 583 start-page: 127 year: 2020 ident: 863_CR10 publication-title: Nature doi: 10.1038/s41586-020-2403-9 – volume: 2 start-page: 418 year: 2017 ident: 863_CR101 publication-title: JACC Basic Transl Sci doi: 10.1016/j.jacbts.2017.06.005 – volume: 100 start-page: 140 year: 2007 ident: 863_CR212 publication-title: Circ Res doi: 10.1161/01.RES.0000255031.15793.86 – volume: 8 start-page: e3074 year: 2017 ident: 863_CR220 publication-title: Cell Death Dis doi: 10.1038/cddis.2017.470 – volume: 25 start-page: 959 year: 2005 ident: 863_CR104 publication-title: J Cereb Blood Flow Metab doi: 10.1038/sj.jcbfm.9600086 – volume: 3 start-page: 342 year: 2019 ident: 863_CR165 publication-title: Nanotheranostics doi: 10.7150/ntno.37391 – volume: 23 start-page: 8692 year: 2003 ident: 863_CR238 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-25-08692.2003 – volume: 22 start-page: 456 year: 2002 ident: 863_CR119 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/hq0302.104905 – volume: 182 start-page: 733 year: 1992 ident: 863_CR194 publication-title: Biochem Biophys Res Commun doi: 10.1016/0006-291x(92)91793-p – volume: 18 start-page: 911 year: 2004 ident: 863_CR218 publication-title: FASEB J doi: 10.1096/fj.03-1148fje – volume: 9 start-page: 2173 year: 2019 ident: 863_CR26 publication-title: Sci Rep doi: 10.1038/s41598-019-38670-z – volume: 110 start-page: 12 year: 2009 ident: 863_CR59 publication-title: J Neurochem doi: 10.1111/j.1471-4159.2009.06098.x – volume: 99 start-page: 69 year: 2006 ident: 863_CR180 publication-title: Circ Res doi: 10.1161/01.RES.0000229685.37402.80 – volume: 251 start-page: 189 year: 1998 ident: 863_CR216 publication-title: Neurosci Lett doi: 10.1016/s0304-3940(98)00537-0 – volume: 180 start-page: 11 year: 2005 ident: 863_CR174 publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2004.11.016 – volume: 5 start-page: 46 year: 2008 ident: 863_CR50 publication-title: J Neuroinflammation doi: 10.1186/1742-2094-5-46 – volume: 10 start-page: 150 year: 2017 ident: 863_CR53 publication-title: Mucosal Immunol doi: 10.1038/mi.2016.47 – volume: 111 start-page: 1 year: 2019 ident: 863_CR254 publication-title: Biomed Pharmacother doi: 10.1016/j.biopha.2018.12.031 – volume: 177 start-page: 25 year: 2020 ident: 863_CR15 publication-title: Rev Physiol Biochem Pharmacol doi: 10.1007/112_2020_26 – volume: 4 start-page: 245 year: 2008 ident: 863_CR42 publication-title: Curr Hypertens Rev doi: 10.2174/157340208786241336 – volume: 11 start-page: 109 year: 2012 ident: 863_CR57 publication-title: Cell Cycle doi: 10.4161/cc.11.1.18473 – volume: 293 start-page: H743 year: 2007 ident: 863_CR167 publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00166.2007 – volume: 38 start-page: 1621 year: 2017 ident: 863_CR34 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehx239 – volume: 292 start-page: C209 year: 2007 ident: 863_CR60 publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.00157.2006 – volume: 186 start-page: 5489 year: 2011 ident: 863_CR30 publication-title: J Immunol doi: 10.4049/jimmunol.1001623 – volume: 125 start-page: 936 year: 2015 ident: 863_CR13 publication-title: Int J Neurosci doi: 10.3109/00207454.2014.980906 – volume: 36 start-page: 596 year: 2016 ident: 863_CR160 publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X15606714 – volume: 136 start-page: 573 year: 2016 ident: 863_CR199 publication-title: J Neurochem doi: 10.1111/jnc.13422 – volume: 271 start-page: 26174 year: 1996 ident: 863_CR207 publication-title: J Biol Chem doi: 10.1074/jbc.271.42.26174 – volume: 47 start-page: 2160 year: 2016 ident: 863_CR215 publication-title: Stroke doi: 10.1161/STROKEAHA.115.010001 – volume: 91 start-page: 566 year: 1995 ident: 863_CR176 publication-title: Br J Haematol doi: 10.1111/j.1365-2141.1995.tb05348.x – volume: 2018 start-page: 8430123 year: 2018 ident: 863_CR193 publication-title: Neural Plast doi: 10.1155/2018/8430123 – volume: 32 start-page: 1933 year: 2012 ident: 863_CR219 publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2012.97 – volume: 20 start-page: 319 year: 2004 ident: 863_CR6 publication-title: Immunity doi: 10.1016/s1074-7613(04)00046-9 – volume: 160 start-page: 618 year: 1984 ident: 863_CR22 publication-title: J Exp Med doi: 10.1084/jem.160.2.618 – volume: 58 start-page: 1 year: 2020 ident: 863_CR36 publication-title: Clin Rev Allergy Immunol doi: 10.1007/s12016-018-8714-z – volume: 39 start-page: 583 year: 2019 ident: 863_CR173 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/ATVBAHA.118.312037 – volume: 112 start-page: 33 year: 2017 ident: 863_CR115 publication-title: Basic Res Cardiol doi: 10.1007/s00395-017-0622-5 – volume: 117 start-page: 2670 year: 2008 ident: 863_CR3 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.107.740233 – year: 2020 ident: 863_CR177 publication-title: J Rheumatol doi: 10.3899/jrheum.200265 – volume: 28 start-page: 387 year: 2008 ident: 863_CR46 publication-title: J Cereb Blood Flow Metab doi: 10.1038/sj.jcbfm.9600537 – volume: 115 start-page: 288 year: 2015 ident: 863_CR1 publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2014.11.003 – volume: 37 start-page: 2406 year: 2016 ident: 863_CR126 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehw171 – volume: 111 start-page: 1394 year: 2013 ident: 863_CR5 publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2013.01.287 |
| SSID | ssj0014661 |
| Score | 2.5641553 |
| SecondaryResourceType | review_article |
| Snippet | Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic complications still account for substantial morbidity and mortality... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 23 |
| SubjectTerms | Animals Anti-Inflammatory Agents - adverse effects Anti-Inflammatory Agents - therapeutic use Arteriosclerosis Atherosclerosis Cardiology Cardiovascular Diseases - drug therapy Cardiovascular Diseases - immunology Cardiovascular Diseases - metabolism Cardiovascular Diseases - physiopathology Cardiovascular System - drug effects Cardiovascular System - immunology Cardiovascular System - metabolism Cardiovascular System - physiopathology Cerebral infarction Cerebrovascular diseases Cerebrovascular Disorders - drug therapy Cerebrovascular Disorders - immunology Cerebrovascular Disorders - metabolism Cerebrovascular Disorders - physiopathology Clinical trials Crosstalk Cytokines Cytokines - antagonists & inhibitors Cytokines - metabolism Humans Inflammation Inflammation - drug therapy Inflammation - immunology Inflammation - metabolism Inflammation - physiopathology Inflammation Mediators - antagonists & inhibitors Inflammation Mediators - metabolism Intracellular signalling Ischemia Medicine Medicine & Public Health Modulation Molecular Targeted Therapy Morbidity Myocardial infarction Review Side effects Signal Transduction Therapeutic applications Therapeutic targets Transcription activation Transcription factors Vascular diseases |
| SummonAdditionalLinks | – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8QwEB58gHgR31ZXieBNg90mbdqTyKKswnpS2FtJ80BRumpX0H_vJJutrqKXXpLSZmaS-SbzAjgyphBxVhTUMKkpT3NDEcfhQ9lca9m1qTcUBzdZ_45fD9NhuHBrQljl9Ez0B7UeKXdHfupUtfMRFPHZ8wt1XaOcdzW00JiHxS4iEde6QQxbgwsPAV8vFeU4pjni7JA041PnXFKqy01GYxpRPaPvs4rpF9r8HTT5w3PqFdLlKqwEJEnOJ6xfgzlTr8PSIPjKN-Cq9zEePbqodiIb8i3PikyivxuCeJUoH49Kiaw1UeYVLeQ2OJUE502zCXeXF7e9Pg2NE6jigo9pIqTl1gojmTY6zhRXCNOULrLUZJlMkQVJjrag5ZrJKq0sq3Ib56riUiMZc7YFC_WoNjtAbJFUXFmFql5zzbmUCJKkNdJ0BbPGRNCdUq1Uoaq4a27xVLb1kD2lS6R06Sldvkdw3L7zPKmp8e_szpQZZdhfTfklDREctsO4M5y7Q9Zm9ObnZIlwfvUItie8az_HGA4kWRqBmOFqO8FV3Z4dqR_uffVtUaDhnbAITqb8__qtv1ex-_8q9mA5cbLo42Q6sDB-fTP7iHbG1YEX6U_6q_1i priority: 102 providerName: ProQuest |
| Title | Cytokines as therapeutic targets for cardio- and cerebrovascular diseases |
| URI | https://link.springer.com/article/10.1007/s00395-021-00863-x https://www.ncbi.nlm.nih.gov/pubmed/33770265 https://www.proquest.com/docview/2505575190 https://www.proquest.com/docview/2506277001 https://pubmed.ncbi.nlm.nih.gov/PMC7997823 |
| Volume | 116 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3dT9swED8xkKa9oDHGFj4qI_EGltLYsZPHtmqBISqEqFSeIscf2gRKp7ZI8N9zdtOMwjaJF_vBl687O_6dfndngCNrcxmLPKeWKUN5mlmKOA4b7TJjVNulwVG8HIqzEf8xTsd1mRyfC_OKv_fFPlnIIUanF9E3o4gXN1L88frZ3BO9hjHgItRGxTkb0wwxdZ0g8_d7rG5Cb5Dl2wDJVyxp2HwGn2GzRo2kszDzFqzZ6gt8vKx58W047z3NJ3c-gp2oGXmRU0UWkd4zgtiU6BB7SomqDNF2it5wE4hKaqJm9hVGg_5N74zWhyRQzSWf00Qqx52TVjFjTSw01wjJtMlFaoVQKao7ydDvc9wwVaalY2Xm4kyXXBkEbxnbgfVqUtnvQFyelFw7jdu64YZzpRAQKWeVbUvmrI2gvdRaoesK4v4gi_uiqX0cNF2gpoug6eIxguPmmt-L-hn_ld5fGqOo19Ks8CDNs0N5HMFhM4yrwFMbqrKThyAjEuk59Ai-LWzXPI4xHEhEGoFcsWoj4Ctsr45Uv36GStsyRyc7YRGcLO3_57X-_RW77xPfg0-Jn5shRmYf1ufTB3uASGdetuCDHMsWbHQG3e7Q96e3F33su_3h1XUrLABsR0nnGfX9_S8 |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VrQS9IN4EChgJTmCRtR0nOVQISqtd2l0h1Eq9pY4fogJlS7MV7Z_jtzH2OilLRW-95GInsWfG9jeeF8Ara8s8lWVJLVeGiqywFHEcPrQrjFFDlwVFcTKVo33x-SA7WIHfXSyMd6vs9sSwUZuZ9nfk7_xR7W0EZfr--Cf1VaO8dbUroaFiaQWzEVKMxcCOHXv-C1W4dmP8Cfn9mrHtrb3NEY1VBqgWuZhTlisnnMut4saaVGqhEdNoU8rMSqkyHC8rUHFywnBVZ7XjdeHSQtdCGUQ_Bcfv3oBV4S9QBrD6cWv65WtvxxAyZGzFlZTSApF-DNsJwXs-LNZHR6M6j3oFp2fLR-MlvHvZbfMf2204ErfvwO2IZcmHhfDdhRXb3IObk2itvw_jzfP57Lv3qyeqJX9FepGF_3lLEDETHTxiKVGNIdqeoI7eu8eSaD5qH8D-tRD1IQyaWWMfA3Elq4V2GsGGEUYIpRCmKWeVHebcWZvAsKNapWNec19e40fVZ2QOlK6Q0lWgdHWWwJv-neNFVo8re693zKjiCm-rC3lM4GXfjGvTG1xUY2enoY9kubfsJ_Bowbv-d5xjA5NZAvkSV_sOPu_3cktz9C3k_85LVP0ZT-Btx_-LYf1_Fk-unsULuDXam-xWu-PpzlNYY14ug9fOOgzmJ6f2GWKvef08CjiBw-teU38Axi1CmQ |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1bTxQxFD5BSIgvBu8jqDXRJ22YbTudmQdiFNiwIhtiJOFt7PQSDWQWmSXAX-RXedrtDK5E3niZl3YuPZf2O3NuAG-tLfNUliW1XBkqssJSxHF40a4wRg1cFgzFvbHcORBfDrPDBbjqcmF8WGW3J4aN2ky0_0e-7o9q7yMo03UXwyL2t4YfT35T30HKe1q7dhoqtlkwG6HcWEzy2LWX52jOtRujLeT9O8aG2983d2jsOEC1yMWUslw54VxuFTfWpFILjfhGm1JmVkqV4bezAo0oJwxXdVY7XhcuLXQtlEEkVHB87j1YyvHUR0Nw6fP2eP9b79MQMlRvRa1KaYGoP6bwhEQ-nyLrM6XRtEcbg9OL-WPyBva9GcL5jx83HI_DFXgQcS35NBPEh7Bgm0ewvBc9949htHk5nRz5GHuiWvJX1heZxaK3BNEz0SE6lhLVGKLtKdrrfagsia6k9gkc3AlRn8JiM2nscyCuZLXQTiPwMMIIoRRCNuWssoOcO2sTGHRUq3Ssce5bbRxXfXXmQOkKKV0FSlcXCbzv7zmZVfi4dfZax4wqantbXctmAm_6YdRT73xRjZ2chTmS5d7Ln8CzGe_613GOA0xmCeRzXO0n-Brg8yPNr5-hFniOklYwnsCHjv_Xn_X_Vby4fRWvYRl1q_o6Gu-uwn3mxTIE8KzB4vT0zL5EGDatX0X5JvDjrlXqD-TlRt0 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cytokines+as+therapeutic+targets+for+cardio-+and+cerebrovascular+diseases&rft.jtitle=Basic+research+in+cardiology&rft.au=Liberale%2C+Luca&rft.au=Ministrini%2C+Stefano&rft.au=Carbone%2C+Federico&rft.au=Camici%2C+Giovanni+G.&rft.date=2021-12-01&rft.pub=Springer+Berlin+Heidelberg&rft.issn=0300-8428&rft.eissn=1435-1803&rft.volume=116&rft.issue=1&rft_id=info:doi/10.1007%2Fs00395-021-00863-x&rft.externalDocID=10_1007_s00395_021_00863_x |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0300-8428&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0300-8428&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0300-8428&client=summon |