Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling - Santoro, Rosaria; Scaini, Denis; Severino, Luisa Ulloa; Amadeo, Francesco; Ferrari, Silvia; Bernava, Giacomo; Garoffolo, Gloria; Agrifoglio, Marco; Casalis, Loredana; Pesce, Maurizio (Biomaterials, 2018)
Keywords: actin; atomic force microscopy; Calcific aortic valve disease; compliance; cytoskeleton; gels; humans; inflammation; Mechanosensing; patients; Tissue stiffness; transcription (genetics); transcription factors; Valve interstitial cells; Yes associated protein; Tissue stiffness; Valve interstitial cells; Yes associated protein; Mechanosensing; Calcific aortic valve disease