Postprandial changes in gene expression of cholesterol influx and efflux mediators after intake of SFA compared with n -6 PUFA in subjects with and without familial hypercholesterolaemia: secondary outcomes of a randomised controlled trial - Øyri, Linn K. L.; Narverud, Ingunn; Bogsrud, Martin P.; Hansson, Patrik; Leder, Lena; Byfuglien, Marte G.; Veierød, Marit B.; Thoresen, Magne; Ulven, Stine M.; Holven, Kirsten B. (Journal of nutritional science (Cambridge), 2019)
Keywords: blood sampling; cholesteremic effect; Cholesterol; cross-over studies; energy; Familial hypercholesterolaemia; fasting; Fat quality; Fatty acids; Gene expression; gene expression regulation; genes; group behavior; hypercholesterolemia; LDL receptor; Lipids; Meals; Medical laboratories; Metabolism; mononuclear leukocytes; omega-6 fatty acids; polyunsaturated fatty acids; Postprandial responses; Proteins; randomized clinical trials; reverse transcriptase polymerase chain reaction; statistical models; LDLR, LDL receptor; LDL-C, LDL-cholesterol; CT, cycle threshold; Familial hypercholesterolaemia; PBMC, peripheral blood mononuclear cells; FH, familial hypercholesterolaemia; Gene expression; Postprandial responses; SREBP, sterol regulatory element binding protein; Fat quality; LDL receptor