Smartphone app-based approximation of time spent with atrial fibrillation and symptoms in patients after catheter ablation: data from the TeleCheck-AF project

Abstract Aims Reduction of atrial fibrillation (AF) burden is the preferred outcome measure over categorical AF rhythm recurrence after AF ablation. In this sub-analysis of the TeleCheck-AF project, we tested the feasibility of smartphone app-based approximation of time spent with AF and/or symptoms...

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Published inEuropace (London, England) Vol. 26; no. 10
Main Authors Sandgren, Emma, Hermans, Astrid N L, Gawalko, Monika, Betz, Konstanze, Sohaib, Afzal, Fung, Chi Ho, Hillmann, Henrike A K, van der Velden, Rachel M J, Verhaert, Dominique, Scherr, Daniel, Sultan, Arian, Steven, Daniel, Pisters, Ron, Hemels, Martin, Lodziński, Piotr, Chaldoupi, Sevasti-Maria, Gupta, Dhiraj, Gruwez, Henri, Pluymaekers, Nikki A H A, Hendriks, Jeroen M, Nørregaard, Malene, Manninger, Martin, Duncker, David, Linz, Dominik
Format Journal Article
LanguageEnglish
Published UK Oxford University Press 03.10.2024
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ISSN1099-5129
1532-2092
1532-2092
DOI10.1093/europace/euae247

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Summary:Abstract Aims Reduction of atrial fibrillation (AF) burden is the preferred outcome measure over categorical AF rhythm recurrence after AF ablation. In this sub-analysis of the TeleCheck-AF project, we tested the feasibility of smartphone app-based approximation of time spent with AF and/or symptoms. Methods and results Patients scheduled for at least one teleconsultation during the 12-month follow-up after AF ablation were instructed to use a smartphone photoplethysmography-based application for simultaneous symptom and rhythm monitoring three times daily for 1 week. Proxies of time spent with AF and/or symptoms (% recordings, load, and % days), temporal aggregation of AF and/or symptoms (density), and symptom–rhythm correlation (SRC) were assessed. In total, 484 patients (60% male, 62 ± 9.9 years) were included. Adherence, motivation, and patient satisfaction were high. %AF recordings, AF load, and %AF days (rs = 0.88–0.95) and %symptom recordings, symptom load, and %symptom days (rs = 0.95–0.98) showed positive correlations. The SRC correlated negatively with time spent with symptoms (rs = −0.65–0.90) and with time spent with AF (rs = −0.31–0.34). In patients with paroxysmal AF before ablation and AF during the monitoring period, 87% (n = 39/44) had a low-density score <50% (‘paroxysmal AF pattern’) while 5% (n = 2/44) had a high-density score >90% (‘persistent AF pattern’). Corresponding numbers for patients with persistent AF before ablation were 48% (n = 11/23) and 43% (n = 10/23), respectively. Conclusion On-demand, app-based simultaneous rhythm and symptom assessment provides objective proxies of time spent with AF and/or symptoms and SRC, which may assist in assessing AF and symptom outcomes after AF ablation. Graphical Abstract Graphical Abstract
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Emma Sandgren, Astrid N L Hermans, Monika Gawalko and Konstanze Betz contributed equally to this work.
Conflict of interest: E.S., A.N.L.H., M.G., K.B., A.So., C.H.F., R.M.J.v.d.V., D.V., D.Sc., A.Su., D.St., R.P., M.H., P.L., D.G., H.G., N.A.H.A.P., J.M.H., M.N., M.M., and D.L. declared no conflict of interests. D.D. received modest lecture honorary, travel grants, and/or a fellowship grant from Abbott, AstraZeneca, Biotronik, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, CVRx, Medtronic, Microport, Pfizer, Sanofi, and Zoll. H.A.K.H. received modest lecture honorary and/or a fellowship grant from AstraZeneca, Boston Scientific, and Zoll.
ISSN:1099-5129
1532-2092
1532-2092
DOI:10.1093/europace/euae247