DPYD6 plays an important role in fluoropyrimidine toxicity in addition to DPYD2A and c.2846A>T: a comprehensive analysis in 1254 patients - Del Re, Marzia; Cinieri, Saverio; Michelucci, Angela; Salvadori, Stefano; Loupakis, Fotios; Schirripa, Marta; Cremolini, Chiara; Crucitta, Stefania; Barbara, Cecilia; Di Leo, Angelo; Latiano, Tiziana Pia; Pietrantonio, Filippo; et al. (The pharmacogenomics journal, 2019)
Keywords: 45/22; 45/77; 631/67/69; 692/53/2423; Alleles; Biomedical and Life Sciences; Biomedicine; Cohort Studies; Dihydrouracil Dehydrogenase (NADP) - genetics; Drug-Related Side Effects and Adverse Reactions - genetics; Enzymatic activity; Female; Gene Expression; Genetic analysis; Genotype; Hematology; Human Genetics; Humans; Male; Middle Aged; Neutropenia; Oncology; Pharmacotherapy; Polymorphism, Single Nucleotide - genetics; Psychopharmacology; Pyrimidines - adverse effects; Pyrimidines - therapeutic use; Toxicity