Low Hemoglobin Density as a Measure of Iron Status
Iron deficiency anemia is the commonest cause of anemia in the developing countries. Iron status is the result of the balance between the rate of erythropoiesis and the amount of iron stored in the body. Various biochemical parameters have been used to assess iron status such as iron levels, transfe...
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| Published in | Indian journal of hematology & blood transfusion Vol. 29; no. 2; pp. 75 - 76 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
India
Springer-Verlag
01.06.2013
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0971-4502 0974-0449 0974-0449 |
| DOI | 10.1007/s12288-012-0162-y |
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| Abstract | Iron deficiency anemia is the commonest cause of anemia in the developing countries. Iron status is the result of the balance between the rate of erythropoiesis and the amount of iron stored in the body. Various biochemical parameters have been used to assess iron status such as iron levels, transferrin, transferrin saturation and ferritin, and all of them may be influenced by acute phase response and are also expensive tests 1–4. In our situation where patients cannot afford exhaustive tests to document iron deficiency we utilized the LHD values as a predictor of iron status based on the formula provided by Urrechaga 5. |
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| AbstractList | Iron deficiency anemia is the commonest cause of anemia in the developing countries. Iron status is the result of the balance between the rate of erythropoiesis and the amount of iron stored in the body. Various biochemical parameters have been used to assess iron status such as iron levels, transferrin, transferrin saturation and ferritin, and all of them may be influenced by acute phase response and are also expensive tests 1-4. In our situation where patients cannot afford exhaustive tests to document iron deficiency we utilized the LHD values as a predictor of iron status based on the formula provided by Urrechaga 5. |
| Author | S Latha, B. R. Murthy, Sreedhar Damodar, Sharat Jayanthi, K. J. Raghunath, Sneha T. |
| Author_xml | – sequence: 1 givenname: Sharat surname: Damodar fullname: Damodar, Sharat email: drsharat.damodar@gmail.com organization: Department of Haematology, Narayana Hrudayalaya – sequence: 2 givenname: Sneha T. surname: Raghunath fullname: Raghunath, Sneha T. organization: Department of Haematology, Narayana Hrudayalaya – sequence: 3 givenname: Sreedhar surname: Murthy fullname: Murthy, Sreedhar organization: Department of Laboratory Medicine (Haematology and Biochemistry), Narayana Hrudayalaya – sequence: 4 givenname: K. J. surname: Jayanthi fullname: Jayanthi, K. J. organization: Department of Laboratory Medicine (Haematology and Biochemistry), Narayana Hrudayalaya – sequence: 5 givenname: B. R. surname: S Latha fullname: S Latha, B. R. organization: Department of Laboratory Medicine (Haematology and Biochemistry), Narayana Hrudayalaya |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24426340$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1093/ndt/gfl765 10.1373/49.10.1573 10.1111/j.1751-553X.2008.01127.x 10.1182/blood.V99.4.1489 10.1038/sj.ki.5000404 |
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| Copyright | Indian Society of Haematology & Transfusion Medicine 2012 Indian Society of Haematology & Transfusion Medicine 2013 |
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| Keywords | Low hemoglobin density Iron deficiency anemia |
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| References_xml | – volume: 22 start-page: 1156 issue: 4 year: 2007 end-page: 1162 ident: CR1 article-title: Mature erythrocyte parameters as new markers of functional iron deficiency in haemodialysis: sensitivity and specificity publication-title: Nephrol Dial Transpl doi: 10.1093/ndt/gfl765 – volume: 49 start-page: 1573 issue: 10 year: 2003 end-page: 1578 ident: CR2 article-title: Iron deficiency and erythropoiesis: new diagnostic approaches publication-title: Clin Chem doi: 10.1373/49.10.1573 – volume: 32 start-page: e144 issue: 1 Pt 1 year: 2010 end-page: e150 ident: CR5 article-title: The new mature red cell parameter, low haemoglobin density of the Beckman-Coulter LH750: clinical utility in the diagnosis of iron deficiency publication-title: Int J Lab Hematol doi: 10.1111/j.1751-553X.2008.01127.x – volume: 99 start-page: 1489 issue: 4 year: 2002 end-page: 1491 ident: CR4 article-title: Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency publication-title: Blood doi: 10.1182/blood.V99.4.1489 – volume: 101 start-page: S4 year: 2006 end-page: S8 ident: CR3 article-title: Iron indices: what do they really mean? publication-title: Kidney Int Suppl doi: 10.1038/sj.ki.5000404 – volume: 101 start-page: S4 year: 2006 ident: 162_CR3 publication-title: Kidney Int Suppl doi: 10.1038/sj.ki.5000404 – volume: 49 start-page: 1573 issue: 10 year: 2003 ident: 162_CR2 publication-title: Clin Chem doi: 10.1373/49.10.1573 – volume: 32 start-page: e144 issue: 1 Pt 1 year: 2010 ident: 162_CR5 publication-title: Int J Lab Hematol doi: 10.1111/j.1751-553X.2008.01127.x – volume: 22 start-page: 1156 issue: 4 year: 2007 ident: 162_CR1 publication-title: Nephrol Dial Transpl doi: 10.1093/ndt/gfl765 – volume: 99 start-page: 1489 issue: 4 year: 2002 ident: 162_CR4 publication-title: Blood doi: 10.1182/blood.V99.4.1489 – reference: 14500582 - Clin Chem. 2003 Oct;49(10):1573-8 – reference: 16830699 - Kidney Int Suppl. 2006 May;(101):S4-8 – reference: 19220525 - Int J Lab Hematol. 2010 Feb;32(1 Pt 1):e144-50 – reference: 17237481 - Nephrol Dial Transplant. 2007 Apr;22(4):1156-62 – reference: 11830506 - Blood. 2002 Feb 15;99(4):1489-91 |
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| SubjectTerms | Anemia Blood Transfusion Medicine Hematology Hemoglobin Human Genetics Iron Medicine Medicine & Public Health Oncology Short Communication Vitamin deficiency |
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| Title | Low Hemoglobin Density as a Measure of Iron Status |
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