Synthesis of Piperidine Derivatives with a Quinazoline Ring System as Potential Antihypertensive Agents - TAKAI, HARUKI; SHUTO, KATSUICHI; TERANISHI, MASAYUKI; KUBO, KAZUHIRO; KASUYA, YUTAKA; OBASE, HIROYUKI; SHIGENOBU, KOKI; KARASAWA, AKIRA (Chemical & pharmaceutical bulletin, 1986)
Keywords: Animals; antihypertensive activity; Antihypertensive Agents - chemical synthesis; Blood Pressure - drug effects; Chemical Phenomena; Chemistry; Exact sciences and technology; Heterocyclic compounds; Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings; indole; Male; Organic chemistry; oxidative cleavage; piperidine; Piperidines - chemical synthesis; Preparations and properties; quinazoline; Quinazolines - chemical synthesis; Quinazolines - pharmacology; Rats; Rats, Inbred SHR; Aminoketone; Nitrogen heterocycle; Six membered ring; Bicyclic compound; Antihypertensive agent; Benzenic compound; Ureas; Aromatic compound; Infrared spectrum; NMR spectrum; Biological activity