Prostaglandin E1 and misoprostol increase epidermal growth factor production in 3D-cultured human annulus cells - Gruber, Helen E.; Hoelscher, Gretchen; Loeffler, Bryan; Chow, Yin; Ingram, Jane A.; Halligan, Will; Hanley, Edward N. (The spine journal, 2009)
Keywords: Adult; Aged; Alprostadil - metabolism; Alprostadil - pharmacology; Annulus; Cell proliferation; Cell Proliferation - drug effects; Cells, Cultured; Epidermal growth factor; Epidermal Growth Factor - drug effects; Epidermal Growth Factor - metabolism; Female; Fetus; Fibrinolytic Agents - pharmacology; Growth factor; Humans; Immunohistochemistry; Intervertebral Disc - drug effects; Intervertebral Disc - metabolism; Male; Middle Aged; Misoprostol; Misoprostol - pharmacology; Oligonucleotide Array Sequence Analysis; Orthopedics; Prostaglandin E1; Proteoglycan; Proteoglycans - biosynthesis; Receptor, Epidermal Growth Factor - biosynthesis; Receptor, Epidermal Growth Factor - drug effects; RNA, Messenger - analysis; Cell proliferation; Proteoglycan; Immunohistochemistry; Epidermal growth factor; Annulus; Prostaglandin E1; Misoprostol; Growth factor