Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding - Costa, Ana P.; Court, Michael H.; Burke, Neal S.; Zhu, Zhaohui; Mealey, Katrina L.; Villarino, Nicolas F. (Drug metabolism and disposition, 2019)
Keywords: Albumin; Albumins; Alleles; Animals; Binding; Celecoxib; Celecoxib - pharmacokinetics; Dialysis; Dogs; Drug development; Drug Development - methods; Drugs; Equilibrium dialysis; Female; Gene frequency; Genotyping; Liquid chromatography; Male; Mass spectrometry; Mass spectroscopy; Meloxicam; Meloxicam - pharmacokinetics; Mycophenolic acid; Mycophenolic Acid - pharmacokinetics; Nucleotides; Pharmacokinetics; Phenylurea Compounds - pharmacokinetics; Plasma; Plasma proteins; Polymorphism, Single Nucleotide; Population genetics; Protein Binding - genetics; Proteins; Pyrrolidine; Pyrrolidines - pharmacokinetics; Serum Albumin - genetics; Serum Albumin - metabolism; Single-nucleotide polymorphism; Statistical analysis; Ultracentrifugation; QC; CV; SNP; D01-4582; WSU; ACN; MS/MS; HPLC; PCR