Analysis of c-ErbB1/Epidermal Growth Factor Receptor and c-ErbB2/HER-2 Expression in Bronchial Dysplasia: Evaluation of Potential Targets for Chemoprevention of Lung Cancer - Merrick, Daniel T.; Kittelson, John; Winterhalder, Ralph; Kotantoulas, Georgia; Ingeberg, Steen; Keith, Robert L.; Kennedy, Timothy C.; Miller, York E.; Franklin, Wilbur A.; Hirsch, Fred R. (Clinical cancer research, 2006)
Keywords: Adult; Aged; Aged, 80 and over; Antineoplastic agents; Biological and medical sciences; Biomarkers, Tumor - analysis; Biomarkers, Tumor - genetics; Biopsy; Bronchial Neoplasms - genetics; Bronchial Neoplasms - pathology; Bronchial Neoplasms - prevention & control; Cell Cycle Proteins - analysis; Cell Cycle Proteins - drug effects; Cell Cycle Proteins - genetics; Cell Proliferation - drug effects; Cell Transformation, Neoplastic - genetics; Cell Transformation, Neoplastic - metabolism; Cell Transformation, Neoplastic - pathology; cellular proliferation; Chemoprevention; Disease Progression; Female; Gene Expression Regulation, Neoplastic - drug effects; Gene Expression Regulation, Neoplastic - genetics; growth factor receptor; Humans; Immunohistochemistry; Ki-67 Antigen - analysis; Ki-67 Antigen - genetics; lung cancer; Lung Neoplasms - genetics; Lung Neoplasms - pathology; Lung Neoplasms - prevention & control; Male; Medical sciences; Middle Aged; Minichromosome Maintenance Complex Component 2; Nuclear Proteins - analysis; Nuclear Proteins - drug effects; Nuclear Proteins - genetics; Pharmacology. Drug treatments; Pneumology; Precancerous Conditions - drug therapy; Precancerous Conditions - genetics; Precancerous Conditions - metabolism; premalignant change; Receptor, Epidermal Growth Factor - biosynthesis; Receptor, Epidermal Growth Factor - drug effects; Receptor, Epidermal Growth Factor - genetics; Receptor, ErbB-2 - biosynthesis; Receptor, ErbB-2 - drug effects; Receptor, ErbB-2 - genetics; Sensitivity and Specificity; Tumors of the respiratory system and mediastinum; Lung disease; Evaluation; Dysplasia; Targeting; Respiratory disease; Lung cancer; erbB2 Gene; Malignant tumor; Anticarcinogen; Gene expression; Respiratory system; Bronchopulmonary; Epidermal growth factor receptor; Human Epidermal growth factor Receptor 2; Respiratory tract; Target; Growth factor receptor; C-Onc gene; Bronchus disease; Protooncogene