Switching on lysosomes

The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dor...

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Bibliographic Details
Published in	eLife Vol. 13
Main Authors	Adhikari, Deepak, Carroll, John
Format	Journal Article
Language	English
Published	England eLife Science Publications, Ltd 21.08.2024 eLife Sciences Publications Ltd eLife Sciences Publications, Ltd
Subjects	Acidification Animals Autophagy Biological research Biology, Experimental Cell Biology Developmental Biology ELYSA embryo Embryonic development Embryos endosome Enzymes Fertilization Fertilization - physiology Humans Insight lysosome Lysosomes Lysosomes - metabolism Microscopy oocyte Ovum Ovum - physiology Physiological aspects Proteins United States ELYSA mouse endosome cell biology oocyte fertilization developmental biology embryo lysosome
Online Access	Get full text
ISSN	2050-084X 2050-084X
DOI	10.7554/eLife.102430

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Summary:	The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Editorial-2 ObjectType-Commentary-1
ISSN:	2050-084X 2050-084X
DOI:	10.7554/eLife.102430