Normalization of GRK2 protein and mRNA measures in patients with depression predict response to antidepressants - Matuzany-Ruban, Angela; Golan, Moran; Miroshnik, Nataly; Schreiber, Gabriel; Avissar, Sofia (The international journal of neuropsychopharmacology, 2010)
Keywords: Adult; Antidepressants; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Biomarkers, Pharmacological - blood; Citalopram - pharmacology; Citalopram - therapeutic use; Cyclohexanols - pharmacology; Cyclohexanols - therapeutic use; Depressive Disorder, Major - blood; Depressive Disorder, Major - drug therapy; Female; G-Protein-Coupled Receptor Kinase 2 - blood; Gene Expression Regulation - drug effects; Humans; Kinases; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Male; Mental depression; Middle Aged; Pathophysiology; Proteins; RNA, Messenger - blood; Treatment Outcome; Venlafaxine Hydrochloride; Antidepressant; GRK2; receptor desensitization; post-receptor signal transduction; mood disorders