Glucose starvation induces resistance to metformin through the elevation of mitochondrial multidrug resistance protein 1 - Hwang, Sung‐Hyun; Kim, Myung‐Chul; Ji, Sumin; Yang, Yeseul; Jeong, Yeji; Kim, Yongbaek (Cancer science, 2019)
Keywords: ABC transporters; Adenosine triphosphate; Apoptosis; Apoptosis - drug effects; ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics; Autophagy; Autophagy - drug effects; Biotechnology; Cancer therapies; Carbonyl compounds; Cell cycle; Cell growth; Cell Line; Cell membranes; Cell Proliferation - drug effects; Cell survival; Cell Survival - drug effects; Cell Survival - genetics; Chemoresistance; CRISPR; Cyanides; Depolarization; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Drug resistance; Drug Resistance - genetics; Gene Expression Regulation, Neoplastic - drug effects; Glucose; Glucose - metabolism; glucose starvation; Glycoproteins; Humans; Hyperpolarization; Kinases; MDR1 protein; Medical prognosis; Membrane permeability; Membrane potential; Mesothelioma; Mesothelioma - genetics; Mesothelioma - metabolism; Metabolism; Metformin; Metformin - pharmacology; Mitochondria; Mitochondria - genetics; Mitochondria - metabolism; Mitochondrial permeability transition pore; Multidrug resistance; multidrug resistance protein 1; Original; P-Glycoprotein; Phagocytosis; Proteins; Starvation; Starvation - metabolism; United States--US; San Francisco California; Spain; metformin; multidrug resistance protein 1; drug resistance; mitochondria; glucose starvation