Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients
Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to p...
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| Published in | Brazilian journal of medical and biological research Vol. 40; no. 7; pp. 943 - 948 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
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Brazil
Associação Brasileira de Divulgação Científica
01.07.2007
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0100-879X 1414-431X 1414-431X |
| DOI | 10.1590/S0100-879X2006005000129 |
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| Abstract | Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled). Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70) and hospitalization (US$86.30 vs US$12.88)], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2%) and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system. |
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| AbstractList | Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled). Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70) and hospitalization (US$86.30 vs US$12.88)], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2%) and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system. Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled). Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70) and hospitalization (US$86.30 vs US$12.88)], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2%) and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system.Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled). Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70) and hospitalization (US$86.30 vs US$12.88)], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2%) and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system. |
| Author | Santos, L.A. Faresin, S.M. Santoro, I.L. Fernandes, A.L.G. Oliveira, M.A. |
| AuthorAffiliation | Universidade Federal de São Paulo |
| AuthorAffiliation_xml | – name: Universidade Federal de São Paulo |
| Author_xml | – sequence: 1 givenname: L.A. surname: Santos fullname: Santos, L.A. organization: Universidade Federal de São Paulo, Brasil – sequence: 2 givenname: M.A. surname: Oliveira fullname: Oliveira, M.A. organization: Universidade Federal de São Paulo, Brasil – sequence: 3 givenname: S.M. surname: Faresin fullname: Faresin, S.M. organization: Universidade Federal de São Paulo, Brasil – sequence: 4 givenname: I.L. surname: Santoro fullname: Santoro, I.L. organization: Universidade Federal de São Paulo, Brasil – sequence: 5 givenname: A.L.G. surname: Fernandes fullname: Fernandes, A.L.G. organization: Universidade Federal de São Paulo, Brasil |
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| Cites_doi | 10.1590/S1020-49892005000300007 10.1183/09031936.96.09040636 10.1056/NEJM199203263261304 10.1067/mai.2003.1449 10.1016/S0091-6749(99)70536-1 10.1067/mai.2001.114992 10.1067/mai.2003.30 10.1034/j.1399-3003.1999.14d30.x 10.1590/S0102-35862002000200003 10.1034/j.1399-3003.1999.14d29.x 10.1016/j.rmed.2005.08.012 10.1183/09031936.02.02542001 10.1164/ajrccm.156.3.9611072 10.1067/mai.2000.110470 10.1183/09031936.00.16580200 10.1016/S1081-1206(10)62451-9 10.1016/S0091-6749(00)90180-5 10.1067/mai.2002.122716 |
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| Keywords | Health care costs Health economy Health care resources Asthma |
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| References_xml | – volume: 17 start-page: 191 issn: 1020-4989 year: 2005 ident: ref2 article-title: Asthma control in Latin America: the Asthma Insights and Reality in Latin America (AIRLA) survey publication-title: Rev Panam Salud Publica doi: 10.1590/S1020-49892005000300007 – ident: ref5 – volume: 9 start-page: 636 issn: 0903-1936 year: 1996 ident: ref9 article-title: The costs of asthma publication-title: Eur Respir J doi: 10.1183/09031936.96.09040636 – volume: 326 start-page: 862 issn: 0028-4793 year: 1992 ident: ref11 article-title: An economic evaluation of asthma in the United States publication-title: N Engl J Med doi: 10.1056/NEJM199203263261304 – volume: 54 start-page: 31 issn: 0003-4738 year: 1985 ident: ref24 article-title: Direct and indirect costs associated with the management of childhood asthma publication-title: Ann Allergy – volume: 111 start-page: 1212 issn: 0091-6749 year: 1985 ident: ref25 article-title: A comprehensive study of the direct and indirect costs of adult asthma publication-title: J Allergy Clin Immunol doi: 10.1067/mai.2003.1449 – volume: 103 start-page: 125 issn: 0091-6749 year: 1999 ident: ref1 article-title: Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood publication-title: J Allergy Clin Immunol doi: 10.1016/S0091-6749(99)70536-1 – volume: 51 start-page: 411 issn: 0021-4884 year: 2002 ident: ref3 article-title: Asthma insights and reality in Japan (AIRJ) publication-title: Arerugi – ident: ref17 – ident: ref13 – volume: 107 start-page: S445 issn: 0091-6749 year: 2001 ident: ref8 article-title: Understanding the economic burden of asthma publication-title: J Allergy Clin Immunol doi: 10.1067/mai.2001.114992 – volume: 111 start-page: 263 issn: 0091-6749 year: 2003 ident: ref6 article-title: Asthma control in the Asia-Pacific region: the Asthma Insights and Reality in Asia-Pacific Study publication-title: J Allergy Clin Immunol doi: 10.1067/mai.2003.30 – volume: 14 start-page: 908 issn: 0903-1936 year: 1999 ident: ref22 article-title: Evaluation of an educational programme for socially deprived asthma patients publication-title: Eur Respir J doi: 10.1034/j.1399-3003.1999.14d30.x – volume: 21 start-page: 71 issn: 0102-3586 year: 2002 ident: ref23 article-title: Custo efetividade de programa de educação para adultos asmáticos atendidos em hospital escola de instituição pública publication-title: J Pneumol doi: 10.1590/S0102-35862002000200003 – volume: 14 start-page: 902 issn: 0903-1936 year: 1999 ident: ref15 article-title: Development and validation of a questionnaire to measure asthma control publication-title: Eur Respir J doi: 10.1034/j.1399-3003.1999.14d29.x – volume: No. 13 year: 2001 ident: ref18 article-title: Lista de preços atualizada publication-title: Rev Farm Kairos – volume: 100 start-page: 616 issn: 0954-6111 year: 2006 ident: ref16 article-title: Identifying `well-controlled' and `not well-controlled' asthma using the Asthma Control Questionnaire publication-title: Respir Med doi: 10.1016/j.rmed.2005.08.012 – volume: 20 start-page: 260 issn: 0903-1936 year: 2002 ident: ref10 article-title: Persistent asthma: disease control, resource utilisation and direct costs publication-title: Eur Respir J doi: 10.1183/09031936.02.02542001 – volume: 156 start-page: 787 issn: 1073-449X year: 1997 ident: ref12 article-title: A national estimate of the economic costs of asthma publication-title: Am J Respir Crit Care Med doi: 10.1164/ajrccm.156.3.9611072 – volume: 106 start-page: 782 issn: 0091-6749 year: 2000 ident: ref20 article-title: Association of decreases in asthma mortality with increases in sales of inhaled corticosteroids publication-title: J Allergy Clin Immunol doi: 10.1067/mai.2000.110470 – volume: 16 start-page: 802 issn: 0903-1936 year: 2000 ident: ref4 article-title: Clinical management of asthma in 1999: the Asthma Insights and Reality in Europe (AIRE) study publication-title: Eur Respir J doi: 10.1183/09031936.00.16580200 – volume: 110 start-page: S141 issn: 0091-6749 year: 2002 ident: ref14 article-title: Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma Update on Selected Topics - 2002 publication-title: J Allergy Clin Immunol – volume: 85 start-page: 121 issn: 1081-1206 year: 2000 ident: ref19 article-title: Decreases in asthma mortality in the United States publication-title: Ann Allergy Asthma Immunol doi: 10.1016/S1081-1206(10)62451-9 – volume: 105 start-page: 71 issn: 0091-6749 year: 2000 ident: ref21 article-title: Decrease in asthma mortality rate in Israel from 1991-1995: is it related to increased use of inhaled corticosteroids? 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publication-title: J Allergy Clin Immunol – volume: 51 start-page: 411 year: 2002 end-page: 420 article-title: Asthma insights and reality in Japan (AIRJ) publication-title: Arerugi – volume: 106 start-page: 782 year: 2000 article-title: Association of decreases in asthma mortality with increases in sales of inhaled corticosteroids publication-title: J Allergy Clin Immunol – volume: 14 start-page: 902 year: 1999 end-page: 907 article-title: Development and validation of a questionnaire to measure asthma control publication-title: Eur Respir J – volume: 326 start-page: 862 year: 1992 end-page: 866 article-title: An economic evaluation of asthma in the United States publication-title: N Engl J Med – volume: 21 start-page: 71 year: 2002 end-page: 76 article-title: Custo efetividade de programa de educação para adultos asmáticos atendidos em hospital escola de instituição pública publication-title: J Pneumol – volume: 17 start-page: 191 year: 2005 end-page: 197 article-title: Asthma control in Latin America: the Asthma Insights and Reality in Latin America (AIRLA) survey publication-title: Rev Panam Salud Publica – volume: 109 start-page: S482 year: 2002 end-page: S489 article-title: The burden of asthma with specific reference to the United States publication-title: J Allergy Clin Immunol – volume: 103 start-page: 125 year: 1999 end-page: 138 article-title: Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood publication-title: J Allergy Clin Immunol – volume: 156 start-page: 787 year: 1997 end-page: 793 article-title: A national estimate of the economic costs of asthma publication-title: Am J Respir Crit Care Med – publication-title: Informações de Saúde – volume: 100 start-page: 616 year: 2006 end-page: 621 article-title: Identifying `well-controlled' and `not well-controlled' asthma using the Asthma Control Questionnaire publication-title: Respir Med – volume: 14 start-page: 908 year: 1999 end-page: 914 article-title: Evaluation of an educational programme for socially deprived asthma patients publication-title: Eur Respir J – volume: 54 start-page: 31 year: 1985 end-page: 34 article-title: Direct and indirect costs associated with the management of childhood asthma publication-title: Ann Allergy |
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| SubjectTerms | Adult Asthma Asthma - drug therapy Asthma - economics BIOLOGY Brazil Cost of Illness Cross-Sectional Studies Direct Service Costs - statistics & numerical data Female Health care costs Health care resources Health economy Humans Male MEDICINE, RESEARCH & EXPERIMENTAL Middle Aged Severity of Illness Index Surveys and Questionnaires |
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| Title | Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients |
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