Low-Abundance Drug-Resistant Viral Variants in Chronically HIV-Infected, Antiretroviral Treatment–Naive Patients Significantly Impact Treatment Outcomes - Simen, Birgitte B.; Simons, Jan Fredrik; Hullsiek, Katherine Huppler; Novak, Richard M.; MacArthur, Rodger D.; Baxter, John D.; Huang, Chunli; Lubeski, Christine; Turenchalk, Gregory S.; Braverman, Michael S.; Desany, Brian; Rothberg, Jonathan M.; et al. (The Journal of infectious diseases, 2009)
Keywords: Adult; AIDS; Anti-HIV Agents - therapeutic use; Antiretrovirals; Biological and medical sciences; Chronic Disease; Disease Progression; DNA, Complementary - chemistry; Drug resistance; Drug Resistance, Viral; Female; Fundamental and applied biological sciences. Psychology; Genetic mutation; Genetic Variation; HIV; HIV Infections - drug therapy; HIV Infections - virology; HIV-1 - drug effects; HIV-1 - genetics; HIV/AIDS; Human immunodeficiency virus; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Memory interference; Microbiology; Mutation; Reverse transcriptase inhibitors; RNA; RNA, Viral - genetics; Sequencing; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virology; Infection; Resistance; Immunopathology; Prognosis; Treatment; Microbiology; Viral disease; Antiviral; AIDS; Immune deficiency