Regional Difference of Microcirculation in Patients with Asymmetric Hypertrophic Cardiomyopathy: Transthoracic Doppler Coronary Flow Velocity Reserve Analysis
To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR. We evaluated 61 patients with HC (27 men; mean age 4...
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| Published in | Journal of the American Society of Echocardiography Vol. 26; no. 7; pp. 775 - 782 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Mosby, Inc
01.07.2013
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0894-7317 1097-6795 1097-6795 |
| DOI | 10.1016/j.echo.2013.03.023 |
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| Abstract | To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR.
We evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD.
Compared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = −0.24; P = .008) and relative CFVR (B = −0.34; P = .016).
CFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD. |
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| AbstractList | To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR.
We evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD.
Compared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = −0.24; P = .008) and relative CFVR (B = −0.34; P = .016).
CFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD. To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR. We evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD. Compared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = -0.24; P = .008) and relative CFVR (B = -0.34; P = .016). CFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD. To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR.OBJECTIVETo evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR.We evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD.METHODSWe evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD.Compared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = -0.24; P = .008) and relative CFVR (B = -0.34; P = .016).RESULTSCompared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = -0.24; P = .008) and relative CFVR (B = -0.34; P = .016).CFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD.CONCLUSIONSCFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD. Objective To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left ventricular outflow tract obstruction, demonstrate significant regional differences of CFVR. Methods We evaluated 61 patients with HC (27 men; mean age 49 ± 16 years), including 20 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 41 patients without obstruction (HCM). The control group included 20 age- and sex-matched subjects. Transthoracic Doppler echocardiography CFVR of the left anterior descending coronary artery (LAD) and the posterior descending coronary artery (PD) were performed, including calculation of relative CFVR as the ratio between CFVR LAD and CFVR PD. Results Compared with the controls, all the patients with HC had lower CFVR LAD (2.12 ± 0.53 vs 3.34 ± 0.67; P < .001) and CFVR PD (2.29 ± 0.49 vs 3.21 ± 0.65; P < .001). CFVR LAD in HOCM group in comparison with the HCM group was significantly lower (1.93 ± 0.42 vs 2.22 ± 0.55; P = .047), due to higher basal diastolic coronary flow velocities (0.40 ± 0.09 vs 0.33 ± 0.07 m/sec; P = .002), with similar hyperemic diastolic flow velocities (0.71 ± 0.16 vs 0.76 ± 0.19 m/sec; P = .330), respectively. There was no significant difference in CFVR PD between patients with HOCM and those with HCM (2.33 ± 0.46 vs 2.27 ± 0.50; P = .636), respectively. Relative CFVR was lower in the HOCM group compared with the HCM group (0.84 ± 0.16 vs 0.98 ± 0.14; P = .001). By multivariable regression analysis, left ventricular outflow tract gradient was the independent predictor of CFVR LAD (B = −0.24; P = .008) and relative CFVR (B = −0.34; P = .016). Conclusions CFVR LAD and relative CFVR were significantly lower in patients with HOCM compared with patients with HCM. Regional differences of CFVR are present only in patients with significant left ventricular outflow tract obstruction, which suggests that obstruction per se, by increasing wall stress in basal conditions, leads to higher basal diastolic coronary flow velocities and results in lower CFVR in LAD compared with PD. |
| Author | Beleslin, Branko Dobric, Milan Petrovic, Olga Trifunovic, Danijela Petrovic, Milan Stepanovic, Jelena Djordjevic-Dikic, Ana Vukcevic, Vladan Stankovic, Goran Marinkovic, Jelena Ostojic, Miodrag Vujisic-Tesic, Bosiljka Seferovic, Petar Giga, Vojislav Tesic, Milorad |
| Author_xml | – sequence: 1 givenname: Milorad surname: Tesic fullname: Tesic, Milorad email: misa.tesic@gmail.com organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 2 givenname: Ana surname: Djordjevic-Dikic fullname: Djordjevic-Dikic, Ana organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 3 givenname: Branko surname: Beleslin fullname: Beleslin, Branko organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 4 givenname: Danijela surname: Trifunovic fullname: Trifunovic, Danijela organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 5 givenname: Vojislav surname: Giga fullname: Giga, Vojislav organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 6 givenname: Jelena surname: Marinkovic fullname: Marinkovic, Jelena organization: Institute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia – sequence: 7 givenname: Olga surname: Petrovic fullname: Petrovic, Olga organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 8 givenname: Milan surname: Petrovic fullname: Petrovic, Milan organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 9 givenname: Jelena surname: Stepanovic fullname: Stepanovic, Jelena organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 10 givenname: Milan surname: Dobric fullname: Dobric, Milan organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 11 givenname: Vladan surname: Vukcevic fullname: Vukcevic, Vladan organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 12 givenname: Goran surname: Stankovic fullname: Stankovic, Goran organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 13 givenname: Petar surname: Seferovic fullname: Seferovic, Petar organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 14 givenname: Miodrag surname: Ostojic fullname: Ostojic, Miodrag organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia – sequence: 15 givenname: Bosiljka surname: Vujisic-Tesic fullname: Vujisic-Tesic, Bosiljka organization: Clinic for Cardiology, Clinical Center of Serbia, Belgrade, Serbia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23643850$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1136/hrt.2006.110460 10.1016/S0002-9149(02)03235-6 10.1016/j.amjcard.2008.08.023 10.1007/s002590000300 10.1016/j.jacc.2005.10.050 10.1016/j.ijcard.2003.03.015 10.1056/NEJMra061889 10.1016/S0002-9149(99)80417-2 10.1016/j.echo.2004.03.028 10.1016/j.jjcc.2008.04.004 10.1111/j.1365-2559.2004.01835.x 10.1152/ajpheart.00233.2007 10.1136/heart.84.5.476 10.1016/j.echo.2011.03.010 10.1016/j.carpath.2008.08.003 10.1016/j.jtcvs.2003.11.003 10.1016/j.echo.2005.10.005 10.1016/j.echo.2011.01.004 10.1007/BF03085982 10.1001/jama.287.10.1308 10.1056/NEJMoa025050 10.1016/j.echo.2008.09.011 10.1016/j.jacc.2003.09.046 10.1016/S0195-668X(03)00284-7 10.1016/0735-1097(91)90869-B 10.1152/ajpheart.00077.2011 10.1016/S0140-6736(04)16358-7 10.1016/j.echo.2010.09.003 10.1016/j.echo.2010.12.007 10.1161/CIRCULATIONAHA.106.657023 10.1016/S0735-1097(96)00327-0 10.2967/jnumed.111.096156 10.1114/1.1308503 10.1136/heart.89.6.657 10.1056/NEJM197906143002402 10.1016/0002-9149(94)90469-3 10.1161/01.CIR.96.3.834 10.1136/hrt.77.6.558 |
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| Copyright | 2013 American Society of Echocardiography American Society of Echocardiography Copyright © 2013 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. |
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| Keywords | CFVR NYHA IVS PW LV Coronary microcirculation CFR LAD LVOTG HOCM 2D HCM RPP PD TDE DDT Coronary flow velocity reserve Hypertrophic cardiomyopathy HC PET Left ventricular Left ventricular outflow tract gradient Diastolic deceleration time New York Heart Association Rate pressure product Interventricular septum Posterior descending coronary artery Transthoracic Doppler echocardiography Hypertrophic cardiomyopathy without obstruction Left anterior descending coronary artery Two dimensional Hypertrophic obstructive cardiomyopathy Coronary flow reserve Posterior wall Positron emission tomography |
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| References | Popovic, Kwon, Mishra, Buakhamsri, Greenberg, Thamilarasan (bib26) 2008; 21 Knaapen, Germans, Camici, Rimoldi, Ten Cate, Ten Berg (bib31) 2008; 294 Memmola, Iliceto, Napoli, Cavallari, Santoro, Rizzon (bib22) 1994; 74 Gaibazzi, Rigo, Reverberi (bib14) 2010; 23 Krams, Ten Cate, Carlier, Van Der Steen, Serruys (bib18) 2004; 43 Elliott, McKenna (bib29) 2004; 363 Diamond, Forrester (bib12) 1979; 300 Meimoun, Sayah, Luycx-Bore, Boulanger, Elmkies, Benali (bib10) 2011; 24 Vegsundvag, Holte, Wiseth, Hegbom, Hole (bib35) 2011; 24 Cortigiani, Rigo, Gherardi, Galderisi, Sicari, Picano (bib4) 2008; 102 Blauwet, Ackerman, Edwards, Riehle, Ommen (bib25) 2009; 18 Jorg-Ciopor, Namdar, Turina, Jenni, Schwitter, Turina (bib7) 2004; 128 Kern, Bach, Mechem, Caracciolo, Aguirre, Miller (bib30) 1996; 28 Soliman, Knaapen, Geleijnse, Dijkmans, Anwar, Nemes (bib6) 2007; 93 Celik, Dagdeviren, Yildirim, Gorgulu, Uslu, Eren (bib21) 2004; 17 Hoffman (bib5) 2000; 28 Maron (bib1) 2002; 287 Kim, Minagoe, Mizukami, Zhou, Yoshinaga, Takasaki (bib36) 2008; 52 Lazzeroni, Picano, Dodi, Morozzi, Chiriatti, Lu (bib11) 1995; 75 Timmer, Knaapen, Germans, Dijkmans, Lubberink, Ten Berg (bib9) 2011; 301 Petersen, Jerosch-Herold, Hudsmith, Robson, Francis, Doll (bib19) 2007; 115 Kim, Kim, Sohn, Park, Choi (bib20) 2004; 94 Djordjevic-Dikic, Beleslin, Stepanovic, Giga, Tesic, Dobric (bib15) 2011; 24 Bravo, Pinheiro, Higuchi, Rischpler, Merrill, Santaularia-Tomas (bib34) 2012; 53 Camici, Crea (bib2) 2007; 356 Camici, Chiriatti, Lorenzoni, Bellina, Gistri, Italiani (bib17) 1991; 17 Kofflard, Michels, Krams, Kliffen, Geleijnse, Ten Cate (bib33) 2007; 15 Cecchi, Olivotto, Gistri, Lorenzoni, Chiriatti, Camici (bib3) 2003; 349 Tadamura, Yoshibayashi, Yonemura, Kudoh, Kubo, Motooka (bib32) 2000; 27 Varnava, Elliott, Sharma, McKenna, Davies (bib28) 2000; 84 Crowley, Dardas, Harcombe, Shapiro (bib23) 1997; 77 Watanabe, Akasaka, Yamaura, Akiyama, Kaji, Saito (bib24) 2003; 89 Lang, Bierig, Devereux, Flachskampf, Foster, Pellikka (bib13) 2005; 18 Hughes (bib27) 2004; 44 Lethen, Tries, Brechtken, Kersting, Lambertz (bib38) 2003; 91 Kyriakidis, Dernellis, Androulakis, Kelepeshis, Barbetseas, Anastasakis (bib8) 1997; 96 Olivotto, Cecchi, Gistri, Lorenzoni, Chiriatti, Girolami (bib16) 2006; 47 Lethen, Tries, Kersting, Lambertz (bib37) 2003; 24 Lethen (10.1016/j.echo.2013.03.023_bib37) 2003; 24 Meimoun (10.1016/j.echo.2013.03.023_bib10) 2011; 24 Krams (10.1016/j.echo.2013.03.023_bib18) 2004; 43 Kofflard (10.1016/j.echo.2013.03.023_bib33) 2007; 15 Lazzeroni (10.1016/j.echo.2013.03.023_bib11) 1995; 75 Kern (10.1016/j.echo.2013.03.023_bib30) 1996; 28 Memmola (10.1016/j.echo.2013.03.023_bib22) 1994; 74 Watanabe (10.1016/j.echo.2013.03.023_bib24) 2003; 89 Knaapen (10.1016/j.echo.2013.03.023_bib31) 2008; 294 Bravo (10.1016/j.echo.2013.03.023_bib34) 2012; 53 Diamond (10.1016/j.echo.2013.03.023_bib12) 1979; 300 Lang (10.1016/j.echo.2013.03.023_bib13) 2005; 18 Camici (10.1016/j.echo.2013.03.023_bib2) 2007; 356 Olivotto (10.1016/j.echo.2013.03.023_bib16) 2006; 47 Petersen (10.1016/j.echo.2013.03.023_bib19) 2007; 115 Cortigiani (10.1016/j.echo.2013.03.023_bib4) 2008; 102 Popovic (10.1016/j.echo.2013.03.023_bib26) 2008; 21 Hughes (10.1016/j.echo.2013.03.023_bib27) 2004; 44 Vegsundvag (10.1016/j.echo.2013.03.023_bib35) 2011; 24 Hoffman (10.1016/j.echo.2013.03.023_bib5) 2000; 28 Kim (10.1016/j.echo.2013.03.023_bib20) 2004; 94 Elliott (10.1016/j.echo.2013.03.023_bib29) 2004; 363 Cecchi (10.1016/j.echo.2013.03.023_bib3) 2003; 349 Crowley (10.1016/j.echo.2013.03.023_bib23) 1997; 77 Blauwet (10.1016/j.echo.2013.03.023_bib25) 2009; 18 Tadamura (10.1016/j.echo.2013.03.023_bib32) 2000; 27 Timmer (10.1016/j.echo.2013.03.023_bib9) 2011; 301 Camici (10.1016/j.echo.2013.03.023_bib17) 1991; 17 Jorg-Ciopor (10.1016/j.echo.2013.03.023_bib7) 2004; 128 Djordjevic-Dikic (10.1016/j.echo.2013.03.023_bib15) 2011; 24 Lethen (10.1016/j.echo.2013.03.023_bib38) 2003; 91 Soliman (10.1016/j.echo.2013.03.023_bib6) 2007; 93 Celik (10.1016/j.echo.2013.03.023_bib21) 2004; 17 Varnava (10.1016/j.echo.2013.03.023_bib28) 2000; 84 Gaibazzi (10.1016/j.echo.2013.03.023_bib14) 2010; 23 Kim (10.1016/j.echo.2013.03.023_bib36) 2008; 52 Kyriakidis (10.1016/j.echo.2013.03.023_bib8) 1997; 96 Maron (10.1016/j.echo.2013.03.023_bib1) 2002; 287 |
| References_xml | – volume: 24 start-page: 374 year: 2011 end-page: 381 ident: bib10 article-title: Comparison between non-invasive coronary flow reserve and fractional flow reserve to assess the functional significance of left anterior descending artery stenosis of intermediate severity publication-title: J Am Soc Echocardiogr – volume: 27 start-page: 1340 year: 2000 end-page: 1348 ident: bib32 article-title: Significant regional heterogeneity of coronary flow reserve in pediatric hypertrophic cardiomyopathy publication-title: Eur J Nucl Med – volume: 75 start-page: 810 year: 1995 end-page: 813 ident: bib11 article-title: Dipyridamole echocardiography for diagnosis of coexistent coronary artery disease in hypertrophic cardiomyopathy. Echo-Persantine International Cooperative (EPIC) Study Group—Subproject Hypertrophic Cardiomyopathy publication-title: Am J Cardiol – volume: 300 start-page: 1350 year: 1979 end-page: 1358 ident: bib12 article-title: Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease publication-title: N Engl J Med – volume: 43 start-page: 670 year: 2004 end-page: 677 ident: bib18 article-title: Diastolic coronary vascular reserve: a new index to detect changes in the coronary microcirculation in hypertrophic cardiomyopathy publication-title: J Am Coll Cardiol – volume: 356 start-page: 830 year: 2007 end-page: 840 ident: bib2 article-title: Coronary microvascular dysfunction publication-title: N Engl J Med – volume: 301 start-page: 129 year: 2011 end-page: 137 ident: bib9 article-title: Effects of alcohol septal ablation on coronary microvascular function and myocardial energetics in hypertrophic obstructive cardiomyopathy publication-title: Am J Physiol Heart Circ Physiol – volume: 44 start-page: 412 year: 2004 end-page: 427 ident: bib27 article-title: The pathology of hypertrophic cardiomyopathy publication-title: Histopathology – volume: 21 start-page: 1299 year: 2008 end-page: 1305 ident: bib26 article-title: Association between regional ventricular function and myocardial fibrosis in hypertrophic cardiomyopathy assessed by speckle tracking echocardiography and delayed hyperenhancement magnetic resonance imaging publication-title: J Am Soc Echocardiogr – volume: 18 start-page: 262 year: 2009 end-page: 268 ident: bib25 article-title: Myocardial fibrosis in patients with symptomatic obstructive hypertrophic cardiomyopathy: correlation with echocardiographic measurements, sarcomeric genotypes, and pro-left ventricular hypertrophy polymorphisms involving the renin-angiotensin-aldosterone system publication-title: Cardiovasc Pathol – volume: 24 start-page: 758 year: 2011 end-page: 767 ident: bib35 article-title: Coronary flow velocity reserve in the three main coronary arteries assessed with transthoracic Doppler: a comparative study with quantitative coronary angiography publication-title: J Am Soc Echocardiogr – volume: 28 start-page: 884 year: 2000 end-page: 896 ident: bib5 article-title: Problems of coronary flow reserve publication-title: Ann Biomed Eng – volume: 23 start-page: 1242 year: 2010 end-page: 1250 ident: bib14 article-title: Detection of coronary artery disease by combined assessment of wall motion, myocardial perfusion and coronary flow reserve: a multiparametric contrast stress-echocardiography study publication-title: J Am Soc Echocardiogr – volume: 84 start-page: 476 year: 2000 end-page: 482 ident: bib28 article-title: Hypertrophic cardiomyopathy: the interrelation of disarray, fibrosis, and small vessel disease publication-title: Heart – volume: 24 start-page: 573 year: 2011 end-page: 581 ident: bib15 article-title: Prediction of myocardial functional recovery by noninvasive evaluation of basal and hyperemic coronary flow in patients with previous myocardial infarction publication-title: J Am Soc Echocardiogr – volume: 94 start-page: 167 year: 2004 end-page: 171 ident: bib20 article-title: Transthoracic echocardiographic evaluation of coronary flow reserve in patients with hypertrophic cardiomyopathy publication-title: Int J Cardiol – volume: 74 start-page: 1147 year: 1994 end-page: 1151 ident: bib22 article-title: Coronary flow dynamics and reserve assessed by transesophageal echocardiography in obstructive hypertrophic cardiomyopathy publication-title: Am J Cardiol – volume: 15 start-page: 209 year: 2007 end-page: 215 ident: bib33 article-title: Coronary flow reserve in hypertrophic cardiomyopathy: relation with microvascular dysfunction and pathophysiological characteristics publication-title: Neth Heart J – volume: 77 start-page: 558 year: 1997 end-page: 563 ident: bib23 article-title: Transthoracic Doppler echocardiographic analysis of phasic coronary blood flow velocity in hypertrophic cardiomyopathy publication-title: Heart – volume: 17 start-page: 879 year: 1991 end-page: 886 ident: bib17 article-title: Coronary vasodilation is impaired in both hypertrophied and nonhypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with nitrogen-13 ammonia and positron emission tomography publication-title: J Am Coll Cardiol – volume: 91 start-page: 412 year: 2003 end-page: 417 ident: bib38 article-title: Comparison of transthoracic Doppler echocardiography to intracoronary Doppler guidewire measurements for assessment of coronary flow reserve in the left anterior descending artery for detection of restenosis after coronary angioplasty publication-title: Am J Cardiol – volume: 287 start-page: 1308 year: 2002 end-page: 1320 ident: bib1 article-title: Hypertrophic cardiomyopathy: a systematic review publication-title: JAMA – volume: 24 start-page: 1567 year: 2003 end-page: 1575 ident: bib37 article-title: Validation of noninvasive assessment of coronary flow velocity reserve in the right coronary artery. A comparison of transthoracic echocardiographic results with intracoronary Doppler flow wire measurements publication-title: Eur Heart J – volume: 47 start-page: 1043 year: 2006 end-page: 1048 ident: bib16 article-title: Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy publication-title: J Am Coll Cardiol – volume: 52 start-page: 7 year: 2008 end-page: 16 ident: bib36 article-title: No reflow-like pattern in intramyocardial coronary artery suggests myocardial ischemia in patients with hypertrophic cardiomyopathy publication-title: J Cardiol – volume: 115 start-page: 2418 year: 2007 end-page: 2425 ident: bib19 article-title: Evidence for microvascular dysfunction in hypertrophic cardiomyopathy: new insights from multiparametric magnetic resonance imaging publication-title: Circulation – volume: 128 start-page: 163 year: 2004 end-page: 169 ident: bib7 article-title: Regional myocardial ischemia in hypertrophic cardiomyopathy: impact of myectomy publication-title: J Thorac Cardiovasc Surg – volume: 363 start-page: 1881 year: 2004 end-page: 1891 ident: bib29 article-title: Hypertrophic cardiomyopathy publication-title: Lancet – volume: 17 start-page: 744 year: 2004 end-page: 749 ident: bib21 article-title: Determinants of coronary flow abnormalities in obstructive type hypertrophic cardiomyopathy: noninvasive assessment by transthoracic Doppler echocardiography publication-title: J Am Soc Echocardiogr – volume: 93 start-page: 1204 year: 2007 end-page: 1212 ident: bib6 article-title: Assessment of intravascular and extravascular mechanisms of myocardial perfusion abnormalities in obstructive hypertrophic cardiomyopathy by myocardial contrast echocardiography publication-title: Heart – volume: 294 start-page: H986 year: 2008 end-page: H993 ident: bib31 article-title: Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy publication-title: Am J Physiol Heart Circ Physiol – volume: 96 start-page: 834 year: 1997 end-page: 841 ident: bib8 article-title: Changes in phasic coronary blood flow velocity profile and relative coronary flow reserve in patients with hypertrophic obstructive cardiomyopathy publication-title: Circulation – volume: 18 start-page: 1440 year: 2005 end-page: 1463 ident: bib13 article-title: Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology publication-title: J Am Soc Echocardiogr – volume: 89 start-page: 657 year: 2003 end-page: 658 ident: bib24 article-title: Intramyocardial coronary flow characteristics in patients with hypertrophic cardiomyopathy: non-invasive assessment by transthoracic Doppler echocardiography publication-title: Heart – volume: 28 start-page: 1154 year: 1996 end-page: 1160 ident: bib30 article-title: Variations in normal coronary vasodilatory reserve stratified by artery, gender, heart transplantation and coronary artery disease publication-title: J Am Coll Cardiol – volume: 53 start-page: 407 year: 2012 end-page: 414 ident: bib34 article-title: PET/CT assessment of symptomatic individuals with obstructive and nonobstructive hypertrophic cardiomyopathy publication-title: J Nucl Med – volume: 349 start-page: 1027 year: 2003 end-page: 1035 ident: bib3 article-title: Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy publication-title: N Engl J Med – volume: 102 start-page: 1718 year: 2008 end-page: 1723 ident: bib4 article-title: Prognostic implications of coronary flow reserve on left anterior descending coronary artery in hypertrophic cardiomyopathy publication-title: Am J Cardiol – volume: 93 start-page: 1204 year: 2007 ident: 10.1016/j.echo.2013.03.023_bib6 article-title: Assessment of intravascular and extravascular mechanisms of myocardial perfusion abnormalities in obstructive hypertrophic cardiomyopathy by myocardial contrast echocardiography publication-title: Heart doi: 10.1136/hrt.2006.110460 – volume: 91 start-page: 412 year: 2003 ident: 10.1016/j.echo.2013.03.023_bib38 article-title: Comparison of transthoracic Doppler echocardiography to intracoronary Doppler guidewire measurements for assessment of coronary flow reserve in the left anterior descending artery for detection of restenosis after coronary angioplasty publication-title: Am J Cardiol doi: 10.1016/S0002-9149(02)03235-6 – volume: 102 start-page: 1718 year: 2008 ident: 10.1016/j.echo.2013.03.023_bib4 article-title: Prognostic implications of coronary flow reserve on left anterior descending coronary artery in hypertrophic cardiomyopathy publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2008.08.023 – volume: 27 start-page: 1340 year: 2000 ident: 10.1016/j.echo.2013.03.023_bib32 article-title: Significant regional heterogeneity of coronary flow reserve in pediatric hypertrophic cardiomyopathy publication-title: Eur J Nucl Med doi: 10.1007/s002590000300 – volume: 47 start-page: 1043 year: 2006 ident: 10.1016/j.echo.2013.03.023_bib16 article-title: Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2005.10.050 – volume: 94 start-page: 167 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib20 article-title: Transthoracic echocardiographic evaluation of coronary flow reserve in patients with hypertrophic cardiomyopathy publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2003.03.015 – volume: 356 start-page: 830 year: 2007 ident: 10.1016/j.echo.2013.03.023_bib2 article-title: Coronary microvascular dysfunction publication-title: N Engl J Med doi: 10.1056/NEJMra061889 – volume: 75 start-page: 810 year: 1995 ident: 10.1016/j.echo.2013.03.023_bib11 article-title: Dipyridamole echocardiography for diagnosis of coexistent coronary artery disease in hypertrophic cardiomyopathy. Echo-Persantine International Cooperative (EPIC) Study Group—Subproject Hypertrophic Cardiomyopathy publication-title: Am J Cardiol doi: 10.1016/S0002-9149(99)80417-2 – volume: 17 start-page: 744 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib21 article-title: Determinants of coronary flow abnormalities in obstructive type hypertrophic cardiomyopathy: noninvasive assessment by transthoracic Doppler echocardiography publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2004.03.028 – volume: 52 start-page: 7 year: 2008 ident: 10.1016/j.echo.2013.03.023_bib36 article-title: No reflow-like pattern in intramyocardial coronary artery suggests myocardial ischemia in patients with hypertrophic cardiomyopathy publication-title: J Cardiol doi: 10.1016/j.jjcc.2008.04.004 – volume: 44 start-page: 412 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib27 article-title: The pathology of hypertrophic cardiomyopathy publication-title: Histopathology doi: 10.1111/j.1365-2559.2004.01835.x – volume: 294 start-page: H986 year: 2008 ident: 10.1016/j.echo.2013.03.023_bib31 article-title: Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00233.2007 – volume: 84 start-page: 476 year: 2000 ident: 10.1016/j.echo.2013.03.023_bib28 article-title: Hypertrophic cardiomyopathy: the interrelation of disarray, fibrosis, and small vessel disease publication-title: Heart doi: 10.1136/heart.84.5.476 – volume: 24 start-page: 758 year: 2011 ident: 10.1016/j.echo.2013.03.023_bib35 article-title: Coronary flow velocity reserve in the three main coronary arteries assessed with transthoracic Doppler: a comparative study with quantitative coronary angiography publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2011.03.010 – volume: 18 start-page: 262 year: 2009 ident: 10.1016/j.echo.2013.03.023_bib25 publication-title: Cardiovasc Pathol doi: 10.1016/j.carpath.2008.08.003 – volume: 128 start-page: 163 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib7 article-title: Regional myocardial ischemia in hypertrophic cardiomyopathy: impact of myectomy publication-title: J Thorac Cardiovasc Surg doi: 10.1016/j.jtcvs.2003.11.003 – volume: 18 start-page: 1440 year: 2005 ident: 10.1016/j.echo.2013.03.023_bib13 publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2005.10.005 – volume: 24 start-page: 573 year: 2011 ident: 10.1016/j.echo.2013.03.023_bib15 article-title: Prediction of myocardial functional recovery by noninvasive evaluation of basal and hyperemic coronary flow in patients with previous myocardial infarction publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2011.01.004 – volume: 15 start-page: 209 year: 2007 ident: 10.1016/j.echo.2013.03.023_bib33 article-title: Coronary flow reserve in hypertrophic cardiomyopathy: relation with microvascular dysfunction and pathophysiological characteristics publication-title: Neth Heart J doi: 10.1007/BF03085982 – volume: 287 start-page: 1308 year: 2002 ident: 10.1016/j.echo.2013.03.023_bib1 article-title: Hypertrophic cardiomyopathy: a systematic review publication-title: JAMA doi: 10.1001/jama.287.10.1308 – volume: 349 start-page: 1027 year: 2003 ident: 10.1016/j.echo.2013.03.023_bib3 article-title: Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy publication-title: N Engl J Med doi: 10.1056/NEJMoa025050 – volume: 21 start-page: 1299 year: 2008 ident: 10.1016/j.echo.2013.03.023_bib26 article-title: Association between regional ventricular function and myocardial fibrosis in hypertrophic cardiomyopathy assessed by speckle tracking echocardiography and delayed hyperenhancement magnetic resonance imaging publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2008.09.011 – volume: 43 start-page: 670 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib18 article-title: Diastolic coronary vascular reserve: a new index to detect changes in the coronary microcirculation in hypertrophic cardiomyopathy publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2003.09.046 – volume: 24 start-page: 1567 year: 2003 ident: 10.1016/j.echo.2013.03.023_bib37 article-title: Validation of noninvasive assessment of coronary flow velocity reserve in the right coronary artery. A comparison of transthoracic echocardiographic results with intracoronary Doppler flow wire measurements publication-title: Eur Heart J doi: 10.1016/S0195-668X(03)00284-7 – volume: 17 start-page: 879 year: 1991 ident: 10.1016/j.echo.2013.03.023_bib17 article-title: Coronary vasodilation is impaired in both hypertrophied and nonhypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with nitrogen-13 ammonia and positron emission tomography publication-title: J Am Coll Cardiol doi: 10.1016/0735-1097(91)90869-B – volume: 301 start-page: 129 year: 2011 ident: 10.1016/j.echo.2013.03.023_bib9 article-title: Effects of alcohol septal ablation on coronary microvascular function and myocardial energetics in hypertrophic obstructive cardiomyopathy publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00077.2011 – volume: 363 start-page: 1881 year: 2004 ident: 10.1016/j.echo.2013.03.023_bib29 article-title: Hypertrophic cardiomyopathy publication-title: Lancet doi: 10.1016/S0140-6736(04)16358-7 – volume: 23 start-page: 1242 year: 2010 ident: 10.1016/j.echo.2013.03.023_bib14 article-title: Detection of coronary artery disease by combined assessment of wall motion, myocardial perfusion and coronary flow reserve: a multiparametric contrast stress-echocardiography study publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2010.09.003 – volume: 24 start-page: 374 year: 2011 ident: 10.1016/j.echo.2013.03.023_bib10 article-title: Comparison between non-invasive coronary flow reserve and fractional flow reserve to assess the functional significance of left anterior descending artery stenosis of intermediate severity publication-title: J Am Soc Echocardiogr doi: 10.1016/j.echo.2010.12.007 – volume: 115 start-page: 2418 year: 2007 ident: 10.1016/j.echo.2013.03.023_bib19 article-title: Evidence for microvascular dysfunction in hypertrophic cardiomyopathy: new insights from multiparametric magnetic resonance imaging publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.106.657023 – volume: 28 start-page: 1154 year: 1996 ident: 10.1016/j.echo.2013.03.023_bib30 article-title: Variations in normal coronary vasodilatory reserve stratified by artery, gender, heart transplantation and coronary artery disease publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(96)00327-0 – volume: 53 start-page: 407 year: 2012 ident: 10.1016/j.echo.2013.03.023_bib34 article-title: PET/CT assessment of symptomatic individuals with obstructive and nonobstructive hypertrophic cardiomyopathy publication-title: J Nucl Med doi: 10.2967/jnumed.111.096156 – volume: 28 start-page: 884 year: 2000 ident: 10.1016/j.echo.2013.03.023_bib5 article-title: Problems of coronary flow reserve publication-title: Ann Biomed Eng doi: 10.1114/1.1308503 – volume: 89 start-page: 657 year: 2003 ident: 10.1016/j.echo.2013.03.023_bib24 article-title: Intramyocardial coronary flow characteristics in patients with hypertrophic cardiomyopathy: non-invasive assessment by transthoracic Doppler echocardiography publication-title: Heart doi: 10.1136/heart.89.6.657 – volume: 300 start-page: 1350 year: 1979 ident: 10.1016/j.echo.2013.03.023_bib12 article-title: Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease publication-title: N Engl J Med doi: 10.1056/NEJM197906143002402 – volume: 74 start-page: 1147 year: 1994 ident: 10.1016/j.echo.2013.03.023_bib22 article-title: Coronary flow dynamics and reserve assessed by transesophageal echocardiography in obstructive hypertrophic cardiomyopathy publication-title: Am J Cardiol doi: 10.1016/0002-9149(94)90469-3 – volume: 96 start-page: 834 year: 1997 ident: 10.1016/j.echo.2013.03.023_bib8 article-title: Changes in phasic coronary blood flow velocity profile and relative coronary flow reserve in patients with hypertrophic obstructive cardiomyopathy publication-title: Circulation doi: 10.1161/01.CIR.96.3.834 – volume: 77 start-page: 558 year: 1997 ident: 10.1016/j.echo.2013.03.023_bib23 article-title: Transthoracic Doppler echocardiographic analysis of phasic coronary blood flow velocity in hypertrophic cardiomyopathy publication-title: Heart doi: 10.1136/hrt.77.6.558 |
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| Snippet | To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without left... Objective To evaluate, by noninvasive coronary flow velocity reserve (CFVR), whether patients with asymmetric hypertrophic cardiomyopathy (HC), with or without... |
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| SubjectTerms | Adult Blood Flow Velocity Cardiomyopathy, Hypertrophic - diagnostic imaging Cardiomyopathy, Hypertrophic - physiopathology Cardiovascular Case-Control Studies Chi-Square Distribution Coronary Angiography Coronary Circulation Coronary flow velocity reserve Coronary microcirculation Echocardiography, Doppler Female Humans Hypertrophic cardiomyopathy Linear Models Male Microcirculation Middle Aged Regional Blood Flow Ventricular Outflow Obstruction - diagnostic imaging Ventricular Outflow Obstruction - physiopathology |
| Title | Regional Difference of Microcirculation in Patients with Asymmetric Hypertrophic Cardiomyopathy: Transthoracic Doppler Coronary Flow Velocity Reserve Analysis |
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