Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia
Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corti...
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| Published in | Infection & chemotherapy Vol. 46; no. 3; pp. 209 - 215 |
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| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
01.09.2014
대한감염학회 |
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| Online Access | Get full text |
| ISSN | 2093-2340 1598-8112 2092-6448 2092-6448 |
| DOI | 10.3947/ic.2014.46.3.209 |
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| Abstract | Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy. |
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| AbstractList | Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy. Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembraneformation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies,neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) areknown to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is onlyone reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patientwith influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. Wepresent a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid useor immunosuppressive therapy. KCI Citation Count: 1 Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy.Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy. |
| Author | Yim, Seo-Hyung Yim, Jae-Wan Yu, Jung-Hee Ju, Deok-Yun Lee, Ji-Yong Joo, Eun-Jeong Shin, Dong-Suk Yeom, Joon-Sup Song, Young-Seok Do, Sung-Im Song, Jae-Uk Sohn, Yoon-Jeong |
| AuthorAffiliation | 1 Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea |
| AuthorAffiliation_xml | – name: 2 Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea – name: 1 Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea |
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| Cites_doi | 10.1111/j.1439-0507.2005.01180.x 10.1111/j.1439-0507.2012.02191.x 10.1086/525258 10.1136/thx.50.7.812 10.1007/s00134-012-2673-2 10.1056/NEJMra0808853 10.1097/MD.0b013e31826c2ccf 10.1056/NEJM199103073241003 10.3947/ic.2011.43.1.76 10.1136/thx.54.11.1047 10.1086/317452 10.1111/j.1439-0507.2011.02034.x 10.1097/SMJ.0b013e3181d39008 10.1111/j.1439-0507.1996.tb00156.x 10.1093/clinids/17.3.344 |
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| Snippet | Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or... Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembraneformation, ulcer or... |
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| Title | Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia |
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