Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy - Uribe-Herranz, Mireia; Beghi, Silvia; Ruella, Marco; Parvathaneni, Kalpana; Salaris, Silvano; Kostopoulos, Nektarios; George, Subin S.; Pierini, Stefano; Krimitza, Elisavet; Costabile, Francesca; Ghilardi, Guido; Amelsberg, Kimberly V.; et al. (Molecular therapy, 2023)
Keywords: Animals; antigen cross-presentation; Antigens, CD19; CAR T cell; Cross-Priming; Gastrointestinal Microbiome; gut microbiota; Humans; Immunotherapy; Immunotherapy, Adoptive - methods; Mice; Original; Receptors, Antigen, T-Cell - genetics; Receptors, Chimeric Antigen - genetics; T-Lymphocytes; vancomycin; Vancomycin - pharmacology; vancomycin; gut microbiota; antigen cross-presentation; CAR T cell; immunotherapy