A General Hybrid Modeling Framework for Systems Biology Applications: Combining Mechanistic Knowledge with Deep Neural Networks under the SBML Standard - Pinto, José; Ramos, João R. C.; Costa, Rafael S.; Oliveira, Rui (AI (Basel), 2023)
Keywords: Algorithms; Artificial neural networks; Back propagation; Biology; computational modeling; Coronaviruses; COVID-19; Deep learning; deep neural networks; E coli; Enzyme kinetics; Genomes; hybrid modeling; Hybrid systems; Machine learning; Metabolism; Modelling; Neural networks; Ordinary differential equations; Parameter identification; Process controls; Regularization; SBML; Signal transduction; systems biology