The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety

Summary Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pr...

Full description

Saved in:
Bibliographic Details
Published inAnaesthesia Vol. 76; no. 2; pp. 238 - 250
Main Authors Foo, I., Macfarlane, A. J. R., Srivastava, D., Bhaskar, A., Barker, H., Knaggs, R., Eipe, N., Smith, A. F.
Format Journal Article
LanguageEnglish
Published England Blackwell Publishing Ltd 01.02.2021
Subjects
Administration, Intravenous
Anesthetics
Anesthetics, Local - administration & dosage
Anesthetics, Local - adverse effects
Anesthetics, Local - therapeutic use
Body weight
Chronic pain
Comorbidity
Consensus
efficacy
Humans
idocaine
Informed consent
Infusions, Intravenous
Intravenous administration
Lidocaine
Lidocaine - administration & dosage
Lidocaine - adverse effects
Lidocaine - therapeutic use
Local anesthesia
Nerve Block
Pain
Pain, Postoperative - prevention & control
Patient Safety
Patients
Postoperative period
Recovery
Recovery (Medical)
Recovery of Function
Risk Assessment
safety
Surgery
Treatment Outcome
pain
idocaine
safety
efficacy
Online AccessGet full text
ISSN0003-2409
1365-2044
1365-2044
DOI10.1111/anae.15270

Cover

Abstract Summary Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre‐existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a ‘high‐risk’ medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri‐operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg‐1, calculated using the patient’s ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg‐1.h‐1 for no longer than 24 h is recommended, subject to review and re‐assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.
AbstractList Summary Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre‐existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a ‘high‐risk’ medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri‐operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg‐1, calculated using the patient’s ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg‐1.h‐1 for no longer than 24 h is recommended, subject to review and re‐assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.
Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre‐existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a ‘high‐risk’ medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri‐operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg ‐1 , calculated using the patient’s ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg ‐1 .h ‐1 for no longer than 24 h is recommended, subject to review and re‐assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion. 리도카인 정맥주사는 수술 후 통증 및 회복에 미치는 효과 로 인해 널리 사용되고 있으나, 부적절한 사용 및 오용 시 치 명적일 수 있으며 실제 치명적인 사례들이 보고되어 왔다. 정 맥내 리도카인의 위험‐이익 비율(risk‐benefit ratio)은 수술 의 종류 및 동반질환(기존의 만성 통증 포함)과 같은 환자 요 인에 따라 달라진다. 본 합의 성명서는 세 가지 질문에 답하 는 것을 목적으로 한다. 첫째, 리도카인 정맥주사는 수술 후 통증을 효과적으로 경감하며 회복을 촉진하는가? 둘째, 리 도카인 정맥주사는 안전한가? 셋째, 이 적응증에 대해 리도 카인 정맥주사 사용이 허가되지 않았다는 사실이 사용에 영 향을 미치는가? 저자들은 리도카인 정맥주사가 ‘고위험’ 의약 품으로 간주되어야 한다고 제안한다. 개별 마취과 전문의는 선택된 환자에서 리도카인 정맥주사가 다각적 주술기 통증 관리 전략(multimodal perioperative pain management strategy)의 일부로서 도움이 된다고 느낄 수 있다. 이러한 접 근은 병원 의약품 관리 시스템의 승인을 받아야 하며, 개별 임상적 의사결정은 해당 환자에게 적절한 정보 제공에 입각 한 동의를 받아 이루어져야 한다. 리도카인 정맥주사를 사용 하는 경우, 환자의 이상 체중(ideal body weight)을 사용하 여 계산한 1.5 mg.kg‐1 이하의 초기 투여량을 10분 동안 주입 하기를 권고한다. 그 이후에는 검토 및 재평가에 따라 1.5 mg.kg‐1.h‐1 이하의 속도로 최대 24시간을 넘지 않도록 주입 하는 것을 권고한다. 리도카인 정맥주사를 다른 국소 마취제 중재와 동시에 또는 해당 중재의 작용 기간 내에 사용해서는 안 된다. 여기에는 모든 신경 차단 시행 후 4시간 이내에 정맥 내 리도카인 주입을 시작하지 않으며 정맥내 리도카인 주입 중단 후 4시간 이내에 모든 신경 차단을 시행하지 않는 것이 포함된다.
Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre‐existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a ‘high‐risk’ medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri‐operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg‐1, calculated using the patient’s ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg‐1.h‐1 for no longer than 24 h is recommended, subject to review and re‐assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.
Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk-benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre-existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a 'high-risk' medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri-operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg , calculated using the patient's ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg .h for no longer than 24 h is recommended, subject to review and re-assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.
Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk-benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre-existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a 'high-risk' medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri-operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg-1 , calculated using the patient's ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg-1 .h-1 for no longer than 24 h is recommended, subject to review and re-assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk-benefit ratio of i.v. lidocaine varies with type of surgery and with patient factors such as comorbidity (including pre-existing chronic pain). This consensus statement aims to address three questions. First, does i.v. lidocaine effectively reduce postoperative pain and facilitate recovery? Second, is i.v. lidocaine safe? Third, does the fact that i.v. lidocaine is not licensed for this indication affect its use? We suggest that i.v. lidocaine should be regarded as a 'high-risk' medicine. Individual anaesthetists may feel that, in selected patients, i.v. lidocaine may be beneficial as part of a multimodal peri-operative pain management strategy. This approach should be approved by hospital medication governance systems, and the individual clinical decision should be made with properly informed consent from the patient concerned. If i.v. lidocaine is used, we recommend an initial dose of no more than 1.5 mg.kg-1 , calculated using the patient's ideal body weight and given as an infusion over 10 min. Thereafter, an infusion of no more than 1.5 mg.kg-1 .h-1 for no longer than 24 h is recommended, subject to review and re-assessment. Intravenous lidocaine should not be used at the same time as, or within the period of action of, other local anaesthetic interventions. This includes not starting i.v. lidocaine within 4 h after any nerve block, and not performing any nerve block until 4 h after discontinuing an i.v. lidocaine infusion.
Author Foo, I.
Srivastava, D.
Bhaskar, A.
Macfarlane, A. J. R.
Eipe, N.
Barker, H.
Knaggs, R.
Smith, A. F.
Author_xml – sequence: 1
  givenname: I.
  surname: Foo
  fullname: Foo, I.
  organization: Western General Infirmary
– sequence: 2
  givenname: A. J. R.
  surname: Macfarlane
  fullname: Macfarlane, A. J. R.
  organization: Glasgow Royal Infirmary
– sequence: 3
  givenname: D.
  surname: Srivastava
  fullname: Srivastava, D.
  organization: Raigmore Hospital
– sequence: 4
  givenname: A.
  surname: Bhaskar
  fullname: Bhaskar, A.
  organization: Imperial College Healthcare NHS Trust
– sequence: 5
  givenname: H.
  surname: Barker
  fullname: Barker, H.
  organization: Ashford and St Peter’s Hospitals NHS Foundation Trust
– sequence: 6
  givenname: R.
  surname: Knaggs
  fullname: Knaggs, R.
  organization: University of Nottingham
– sequence: 7
  givenname: N.
  surname: Eipe
  fullname: Eipe, N.
  organization: Ottowa Hospital
– sequence: 8
  givenname: A. F.
  orcidid: 0000-0003-2650-9764
  surname: Smith
  fullname: Smith, A. F.
  email: Andrew.smith@mbht.nhs.uk
  organization: Royal Lancaster Infirmary
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33141959$$D View this record in MEDLINE/PubMed
BookMark eNp9kV9rFDEUxYNU7Lb64geQgC9SmJr_M-PbUmoVir7se8hmbjBlNhmTzJZ58bOb3W1finhfArm_c-Cec4HOQgyA0HtKrmmdzyYYuKaSteQVWlGuZMOIEGdoRQjhDROkP0cXOT8QQllHuzfonHMqaC_7Ffqz-QV4zoCjwz6UZPYQ4pzx6IdojQ-AXUx4irnECZIpfg94qv_YhAEnsHEPaflykEIKdR2DGbGNIUPI1SYXU2AHoeAYMDjnrbHLUZuNg7K8Ra-dGTO8e3ov0ebr7ebmW3P_8-77zfq-sUL2pDF1tkxYuRVK9YwPLW17aaVinR0od5QbBoNinGzBuJYNwrEahOisMVIpfok-nWynFH_PkIve-WxhHE2Aeq1mQrZKdUJ2Ff34An2Icz1tPFCt4pxQ0lbqwxM1b3cw6Cn5nUmLfg62AuQE2BRzTuC09eWYT83Yj5oSfehOH7rTx-6q5OqF5Nn1nzA9wY9-hOU_pF7_WN-eNH8BTSaq3A
CitedBy_id crossref_primary_10_2147_DDDT_S382412
crossref_primary_10_17816_1993_6508_2022_16_1_45_58
crossref_primary_10_12677_ACM_2024_142333
crossref_primary_10_35366_101670
crossref_primary_10_1136_bmjopen_2021_056959
crossref_primary_10_1007_s11695_025_07689_9
crossref_primary_10_1016_j_biopha_2022_113850
crossref_primary_10_1097_AJP_0000000000000995
crossref_primary_10_1155_2022_1888153
crossref_primary_10_1186_s12871_024_02885_z
crossref_primary_10_2147_DDDT_S356880
crossref_primary_10_1111_anae_15400
crossref_primary_10_2147_JPR_S473924
crossref_primary_10_1016_j_bja_2021_04_024
crossref_primary_10_1053_j_jvca_2024_12_028
crossref_primary_10_1177_0310057X231194833
crossref_primary_10_1213_ANE_0000000000006604
crossref_primary_10_1002_jac5_1762
crossref_primary_10_1016_j_aan_2022_07_003
crossref_primary_10_1111_nmo_14289
crossref_primary_10_1016_j_isci_2025_112041
crossref_primary_10_1055_a_2114_4327
crossref_primary_10_1007_s11095_025_03835_1
crossref_primary_10_1007_s00228_023_03498_0
crossref_primary_10_1016_j_accpm_2024_101427
crossref_primary_10_1016_j_xphs_2024_07_012
crossref_primary_10_1007_s44180_021_0019_6
crossref_primary_10_1016_j_jatmed_2024_09_002
crossref_primary_10_1007_s00540_024_03430_5
crossref_primary_10_1016_j_accpm_2021_100922
crossref_primary_10_1016_j_amsu_2021_103124
crossref_primary_10_2147_DDDT_S437599
crossref_primary_10_3389_fonc_2021_688896
crossref_primary_10_35366_116231
crossref_primary_10_1016_j_mpaic_2021_09_005
crossref_primary_10_1111_anae_15506
crossref_primary_10_2106_JBJS_RVW_23_00176
crossref_primary_10_1007_s11916_023_01137_y
crossref_primary_10_1007_s12663_023_02003_5
crossref_primary_10_2147_JPR_S341550
crossref_primary_10_1007_s40140_024_00617_0
crossref_primary_10_1111_anae_15467
crossref_primary_10_1097_ACO_0000000000001002
crossref_primary_10_1111_jog_16053
crossref_primary_10_3390_jcm11123543
crossref_primary_10_7759_cureus_23037
crossref_primary_10_3390_jcm12062312
crossref_primary_10_1097_EJA_0000000000001978
crossref_primary_10_3389_fonc_2023_1101449
crossref_primary_10_3802_jgo_2023_34_e61
crossref_primary_10_1016_j_bja_2023_08_024
crossref_primary_10_1111_anae_16391
crossref_primary_10_3389_fphar_2024_1422778
crossref_primary_10_1016_j_wem_2022_04_010
crossref_primary_10_1089_gyn_2023_0053
crossref_primary_10_1093_ajhp_zxad115
crossref_primary_10_23736_S0375_9393_24_17920_5
crossref_primary_10_1002_pbc_31458
crossref_primary_10_1016_j_bpa_2022_12_003
crossref_primary_10_1136_spcare_2023_004350
crossref_primary_10_7759_cureus_32090
crossref_primary_10_1016_j_wem_2023_01_004
crossref_primary_10_1186_s12871_025_02890_w
crossref_primary_10_1016_j_bja_2021_07_020
crossref_primary_10_1111_anae_15455
crossref_primary_10_1016_j_accpm_2023_101264
crossref_primary_10_1016_j_bja_2023_12_010
crossref_primary_10_1097_EJA_0000000000001987
crossref_primary_10_35366_116234
crossref_primary_10_3389_fmed_2021_706844
crossref_primary_10_36290_aim_2020_057
crossref_primary_10_4103_ija_ija_487_24
crossref_primary_10_1016_j_bja_2023_07_032
crossref_primary_10_1021_acs_jpcb_1c10504
crossref_primary_10_3389_fbioe_2022_1072205
crossref_primary_10_35119_myja_v3i2_70
crossref_primary_10_1080_14737175_2023_2284872
crossref_primary_10_3389_fonc_2023_1101582
crossref_primary_10_3390_cimb45010049
crossref_primary_10_1016_j_jogc_2021_06_010
crossref_primary_10_1111_anae_15846
crossref_primary_10_3390_jcm12113772
crossref_primary_10_1186_s13063_022_06021_5
crossref_primary_10_3389_fvets_2023_1287844
crossref_primary_10_1007_s00423_023_02937_x
crossref_primary_10_2147_CIA_S419835
crossref_primary_10_1111_anae_16531
crossref_primary_10_1097_CM9_0000000000003540
crossref_primary_10_1097_EJA_0000000000001712
crossref_primary_10_1016_j_bja_2023_03_026
crossref_primary_10_1016_j_bja_2023_03_027
crossref_primary_10_1111_anae_15440
crossref_primary_10_4103_sja_sja_236_22
crossref_primary_10_1016_j_bja_2024_01_019
crossref_primary_10_17085_apm_21094
crossref_primary_10_1007_s00405_024_09045_6
crossref_primary_10_1097_AJP_0000000000001135
crossref_primary_10_3390_healthcare9030333
crossref_primary_10_1007_s40262_024_01373_4
crossref_primary_10_1097_AJP_0000000000000960
crossref_primary_10_1111_pan_15015
crossref_primary_10_1177_10806032241248422
crossref_primary_10_23736_S0375_9393_23_17291_9
crossref_primary_10_3390_jcm10040719
crossref_primary_10_3390_cryst12060798
crossref_primary_10_1186_s42077_023_00390_y
crossref_primary_10_4103_ija_ija_126_22
crossref_primary_10_1111_anae_15439
crossref_primary_10_1097_ACO_0000000000001308
crossref_primary_10_4103_ija_ija_1010_23
crossref_primary_10_5812_aapm_146868
crossref_primary_10_1186_s12871_022_01632_6
crossref_primary_10_1186_s12871_022_01861_9
crossref_primary_10_36290_far_2022_003
crossref_primary_10_1016_j_mpaic_2024_09_005
crossref_primary_10_1097_MD_0000000000038177
crossref_primary_10_1111_anae_15434
crossref_primary_10_1111_pan_14608
crossref_primary_10_3389_fmed_2022_939098
crossref_primary_10_1016_j_cpsurg_2023_101332
crossref_primary_10_1080_07853890_2024_2315229
crossref_primary_10_3389_fneur_2023_1202426
crossref_primary_10_2147_DDDT_S496608
crossref_primary_10_1213_ANE_0000000000006383
crossref_primary_10_1016_j_wem_2023_05_005
crossref_primary_10_1016_j_bja_2022_03_031
crossref_primary_10_35172_rvz_2024_v31_1568
crossref_primary_10_1186_s13063_022_06469_5
crossref_primary_10_23736_S0375_9393_23_17350_0
crossref_primary_10_17816_1993_6508_2021_15_1_5_8
crossref_primary_10_1007_s11916_024_01276_w
crossref_primary_10_1111_bph_15800
crossref_primary_10_1016_j_bjao_2023_100138
crossref_primary_10_1016_j_diabres_2022_109928
crossref_primary_10_1111_anae_16595
crossref_primary_10_23736_S0375_9393_22_16907_5
crossref_primary_10_4103_jmas_jmas_265_23
crossref_primary_10_1186_s12871_024_02640_4
crossref_primary_10_1007_s40122_022_00442_5
crossref_primary_10_1016_j_jclinane_2024_111528
crossref_primary_10_12968_hmed_2021_0524
crossref_primary_10_1016_j_bjorl_2024_101403
crossref_primary_10_56126_75_4_57
crossref_primary_10_5937_medi57_53024
crossref_primary_10_1111_anae_16228
crossref_primary_10_1097_EJA_0000000000001945
crossref_primary_10_1186_s13023_023_02829_9
crossref_primary_10_1089_jpm_2023_0022
Cites_doi 10.1136/bmj.323.7303.42
10.3109/15563650.2015.1121270
10.1111/anae.13368
10.1186/s13741-019-0112-4
10.1097/ALN.0b013e318190b263
10.1097/00000539-199607000-00018
10.9738/INTSURG-D-14-00225.1
10.1007/s00540-009-0738-3
10.1016/S1053-0770(05)80138-7
10.1007/s12630-010-9332-2
10.1213/01.ANE.0000104582.71710.EE
10.7326/0003-4819-87-6-700
10.1093/bja/aeq416
10.1056/NEJM197412192912504
10.1017/9781139626798
10.1111/anae.13730
10.1007/BF03022051
10.1111/j.1399-6576.2009.02165.x
10.1002/bjs.6375
10.1111/anae.14705
10.1016/S0002-8703(76)80252-9
10.1097/AAP.0000000000000398
10.1002/14651858.CD003006.pub4
10.1111/j.1365-2044.1949.tb05802.x
10.1097/EJA.0b013e328356bad6
10.1097/00000542-200701000-00007
10.1097/AJP.0b013e31823b9cc8
10.1007/s00464-011-1684-3
10.1046/j.1365-2346.1997.00112.x
10.1001/jama.282.11.1054
10.1136/bmj.h1481
10.1503/cjs.009613
10.1111/papr.12442
10.1016/j.bja.2019.06.014
10.1177/0300060513505493
10.1097/ALN.0000000000001527
10.1002/14651858.CD006459.pub2
10.2165/10898560-000000000-00000
10.1097/EJA.0b013e328343c569
10.5313/wja.v4.i2.17
10.1177/2049463719873021
10.1007/s00268-015-3105-6
10.1093/bja/ael217
10.1016/S0034-7094(10)70041-6
10.1016/j.amjsurg.2008.10.015
10.1111/j.1460-9592.2010.03421.x
10.1007/s10151-013-1065-0
10.1001/jama.1960.03020140029007
10.1136/bmj.327.7428.1379
10.1111/anae.14582
10.1007/s40801-020-00205-8
10.1097/DCR.0b013e318259bcd8
10.2147/LRA.S119483
10.1093/bja/23.3.153
10.1097/00003643-199811000-00007
10.1002/14651858.CD012212.pub2
10.1111/anae.14570
10.1111/ans.12550
10.1007/BF02527813
10.1016/S0304-3959(03)00176-3
10.1093/bja/59.6.721
10.1213/ANE.0b013e318277a270
10.1111/j.1749-6632.1971.tb46915.x
10.1111/j.1365-2044.1961.tb13426.x
10.1213/01.ANE.0000142551.92340.CC
10.1016/0197-2456(81)90056-8
10.1001/archinte.1981.00340010039011
10.1016/0197-2456(95)00134-4
10.4103/joacp.JOACP_341_15
10.1056/NEJM196712072772301
10.7326/0003-4819-78-4-499
10.1002/14651858.CD009642.pub2
10.1002/14651858.CD002192.pub2
10.1089/lap.2012.0542
10.1097/EJA.0b013e32834592a8
10.1002/14651858.CD009642.pub3
10.1007/BF03013207
10.1007/BF03016348
10.1111/aas.12773
10.1093/bja/aep103
10.1136/dtb.2009.03.0012
10.1213/ANE.0b013e3181bab1bd
10.1097/AAP.0b013e3181e8d5da
10.1111/j.1365-2044.1958.tb08045.x
10.1097/SLA.0b013e31805dac11
10.1213/ANE.0b013e3182662e01
10.1016/j.pain.2006.06.018
10.1213/00000539-196105000-00011
10.1097/ALN.0b013e31817b5a9b
10.1111/anae.14519
10.1007/s12630-010-9407-0
10.1016/j.jclinane.2016.07.021
10.1097/00000542-199812000-00011
10.1097/00000539-199802000-00003
10.1213/00000539-198510000-00005
10.1093/bja/29.2.81
ContentType Journal Article
Copyright 2020 The Authors. published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.
2020 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.
2020. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: 2020 The Authors. published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.
– notice: 2020 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.
– notice: 2020. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID 24P
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7T5
7U7
C1K
H94
K9.
7X8
DOI 10.1111/anae.15270
DatabaseName Wiley Online Library Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Immunology Abstracts
Toxicology Abstracts
Environmental Sciences and Pollution Management
AIDS and Cancer Research Abstracts
ProQuest Health & Medical Complete (Alumni)
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
AIDS and Cancer Research Abstracts
ProQuest Health & Medical Complete (Alumni)
Immunology Abstracts
Toxicology Abstracts
Environmental Sciences and Pollution Management
MEDLINE - Academic
DatabaseTitleList
CrossRef
AIDS and Cancer Research Abstracts
MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: 24P
  name: Wiley Online Library Open Access
  url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
EISSN 1365-2044
EndPage 250
ExternalDocumentID 33141959
10_1111_anae_15270
ANAE15270
Genre article
Guideline
Journal Article
GroupedDBID ---
.3N
.55
.GA
.GJ
.Y3
05W
0R~
10A
1OC
23M
24P
31~
33P
36B
3O-
3SF
4.4
50Y
50Z
51W
51X
52M
52N
52O
52P
52R
52S
52T
52U
52V
52W
52X
53G
5GY
5HH
5LA
5RE
5VS
66C
6J9
6P2
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A01
A03
AAESR
AAEVG
AAHHS
AAHQN
AAIPD
AAMNL
AANLZ
AAONW
AAQQT
AASGY
AAWTL
AAXRX
AAYCA
AAZKR
ABCQN
ABCUV
ABEML
ABJNI
ABLJU
ABPVW
ABQWH
ABXGK
ACAHQ
ACCFJ
ACCZN
ACGFO
ACGFS
ACGOF
ACMXC
ACPOU
ACPRK
ACSCC
ACXBN
ACXQS
ADBBV
ADBTR
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADXAS
ADZMN
ADZOD
AEEZP
AEGXH
AEIGN
AEIMD
AENEX
AEQDE
AEUQT
AEUYR
AFBPY
AFEBI
AFFNX
AFFPM
AFGKR
AFPWT
AFRAH
AFWVQ
AFZJQ
AHBTC
AHEFC
AHMBA
AI.
AIACR
AIAGR
AITYG
AIURR
AIWBW
AJBDE
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
ALVPJ
AMBMR
AMYDB
ATUGU
AZBYB
AZVAB
BAFTC
BFHJK
BHBCM
BMXJE
BROTX
BRXPI
BY8
C45
CAG
COF
CS3
D-6
D-7
D-E
D-F
DC6
DCZOG
DPXWK
DR2
DRFUL
DRMAN
DRSTM
EBS
EJD
EMOBN
ESX
EX3
F00
F01
F04
F5P
FUBAC
FZ0
G-S
G.N
GODZA
H.X
HF~
HGLYW
HZI
HZ~
IHE
IX1
J0M
J5H
K48
KBYEO
L7B
LATKE
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
MEWTI
MK4
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
N04
N05
N9A
NF~
O66
O9-
OIG
OK1
OVD
P2P
P2W
P2X
P2Z
P4B
P4D
PQQKQ
Q.N
Q11
QB0
R.K
ROL
RX1
SUPJJ
TEORI
UB1
V8K
V9Y
VH1
W8V
W99
WBKPD
WHWMO
WIH
WIJ
WIK
WIN
WOHZO
WOW
WQJ
WRC
WUP
WVDHM
WXI
WXSBR
X7M
XG1
YFH
YOC
YUY
ZCG
ZGI
ZXP
ZZTAW
~IA
~WT
AAFWJ
AAYXX
AEYWJ
AGHNM
AGYGG
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7T5
7U7
AAMMB
AEFGJ
AGXDD
AIDQK
AIDYY
C1K
H94
K9.
7X8
ID FETCH-LOGICAL-c4590-aaaab24c5b466923d71795c5628cd13f13a2ed6230beaf72d4f213648caa5663
IEDL.DBID 24P
ISSN 0003-2409
1365-2044
IngestDate Fri Jul 11 07:33:33 EDT 2025
Sat Jul 26 03:28:37 EDT 2025
Thu Apr 03 07:07:49 EDT 2025
Thu Apr 24 23:01:30 EDT 2025
Tue Jul 01 02:13:15 EDT 2025
Wed Jan 22 16:32:08 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords pain
idocaine
safety
efficacy
Language English
License Attribution-NonCommercial-NoDerivs
2020 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c4590-aaaab24c5b466923d71795c5628cd13f13a2ed6230beaf72d4f213648caa5663
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Article-2
ObjectType-Instructional Material/Guideline-1
ObjectType-Feature-3
content type line 23
ORCID 0000-0003-2650-9764
OpenAccessLink https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fanae.15270
PMID 33141959
PQID 2476330107
PQPubID 41853
PageCount 13
ParticipantIDs proquest_miscellaneous_2457668458
proquest_journals_2476330107
pubmed_primary_33141959
crossref_citationtrail_10_1111_anae_15270
crossref_primary_10_1111_anae_15270
wiley_primary_10_1111_anae_15270_ANAE15270
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate February 2021
PublicationDateYYYYMMDD 2021-02-01
PublicationDate_xml – month: 02
  year: 2021
  text: February 2021
PublicationDecade 2020
PublicationPlace England
PublicationPlace_xml – name: England
– name: Oxford
PublicationTitle Anaesthesia
PublicationTitleAlternate Anaesthesia
PublicationYear 2021
Publisher Blackwell Publishing Ltd
Publisher_xml – name: Blackwell Publishing Ltd
References 2010; 54
2009; 47
2015; 39
2007; 106
2010; 57
2013; 23
1958; 13
2015; 100
1981; 141
1949; 4
2009; 110
2009; 198
2008; 109
1999; 46
1951; 23
1967; 277
2016; 71
2011; 58
1985; 64
2012; 55
1998; 86
1998; 89
2019; 123
2016; 35
2010; 60
1992; 6
1998; 15
2017; 72
2020; 7
2003; 327
2020; 2
2005; 100
2013; 116
2017; 33
1997; 14
2016; 41
2014; 57
1971; 179
2011; 21
1961; 40
2012; 29
2012; 28
2014; 18
2011; 25
2010; 70
2011; 28
2006; 126
2017; 126
1974; 291
2019; 8
2007; 246
2009; 23
1960; 172
1995; 9
2015; 15
2006; 97
1996; 17
2015; 4
2010; 35
2019; 74
2010
1973; 78
1981; 2
2009
2016; 54
2008; 55
1977; 87
2008; 95
2014; 84
2016; 16
2001; 323
1961; 16
1987; 59
2014; 42
2004; 98
2015; 350
2003; 105
2011; 106
2020; 75
2017; 17
1999; 282
1976; 92
2015; 65
1996; 83
2019
2005; 52
2018
2016
2015
2016; 60
2014
1957; 29
2012; 115
2009; 109
2009; 103
2016; 9
e_1_2_12_6_1
Oliveira CMB (e_1_2_12_88_1) 2010; 60
e_1_2_12_2_1
e_1_2_12_17_1
e_1_2_12_20_1
e_1_2_12_66_1
e_1_2_12_43_1
e_1_2_12_85_1
e_1_2_12_24_1
e_1_2_12_47_1
e_1_2_12_89_1
e_1_2_12_62_1
e_1_2_12_81_1
e_1_2_12_100_1
e_1_2_12_28_1
Blessberger H (e_1_2_12_63_1) 2019
e_1_2_12_104_1
e_1_2_12_31_1
e_1_2_12_77_1
e_1_2_12_54_1
e_1_2_12_96_1
e_1_2_12_35_1
e_1_2_12_58_1
e_1_2_12_12_1
e_1_2_12_73_1
e_1_2_12_50_1
e_1_2_12_92_1
e_1_2_12_3_1
e_1_2_12_18_1
e_1_2_12_21_1
e_1_2_12_44_1
e_1_2_12_86_1
Christie LE (e_1_2_12_16_1) 2015; 15
e_1_2_12_107_1
e_1_2_12_25_1
e_1_2_12_48_1
e_1_2_12_67_1
Schug SA (e_1_2_12_105_1) 2015
Singh S (e_1_2_12_101_1) 2017; 33
e_1_2_12_40_1
e_1_2_12_82_1
e_1_2_12_29_1
e_1_2_12_103_1
e_1_2_12_32_1
e_1_2_12_55_1
e_1_2_12_74_1
e_1_2_12_97_1
e_1_2_12_36_1
e_1_2_12_59_1
e_1_2_12_78_1
e_1_2_12_13_1
e_1_2_12_7_1
e_1_2_12_51_1
e_1_2_12_70_1
e_1_2_12_93_1
e_1_2_12_4_1
e_1_2_12_19_1
e_1_2_12_38_1
e_1_2_12_41_1
e_1_2_12_87_1
e_1_2_12_106_1
Eipe N (e_1_2_12_10_1) 2016; 16
e_1_2_12_22_1
e_1_2_12_64_1
e_1_2_12_45_1
e_1_2_12_26_1
e_1_2_12_83_1
e_1_2_12_60_1
e_1_2_12_49_1
e_1_2_12_102_1
e_1_2_12_52_1
e_1_2_12_98_1
e_1_2_12_33_1
e_1_2_12_75_1
e_1_2_12_56_1
e_1_2_12_37_1
e_1_2_12_79_1
e_1_2_12_14_1
e_1_2_12_90_1
e_1_2_12_8_1
e_1_2_12_94_1
e_1_2_12_71_1
e_1_2_12_5_1
e_1_2_12_39_1
e_1_2_12_42_1
e_1_2_12_65_1
e_1_2_12_23_1
e_1_2_12_46_1
e_1_2_12_69_1
De Oliveira CMB (e_1_2_12_68_1) 2015; 65
e_1_2_12_80_1
e_1_2_12_61_1
e_1_2_12_84_1
e_1_2_12_27_1
e_1_2_12_30_1
e_1_2_12_53_1
e_1_2_12_76_1
e_1_2_12_99_1
e_1_2_12_34_1
e_1_2_12_57_1
e_1_2_12_15_1
e_1_2_12_91_1
e_1_2_12_11_1
e_1_2_12_72_1
e_1_2_12_95_1
e_1_2_12_9_1
33141932 - Anaesthesia. 2021 Feb;76(2):156-160
33591570 - Anaesthesia. 2021 May;76(5):721
References_xml – volume: 97
  start-page: 640
  year: 2006
  end-page: 6
  article-title: Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery
  publication-title: British Journal of Anaesthesia
– volume: 74
  start-page: 508
  year: 2019
  end-page: 17
  article-title: People, systems and safety: resilience and excellence in healthcare practice
  publication-title: Anaesthesia
– volume: 57
  start-page: 759
  year: 2010
  end-page: 66
  article-title: Intravenous lidocaine does not reduce length of hospital stay following abdominal hysterectomy
  publication-title: Canadian Journal of Anaesthesia
– volume: 33
  start-page: 448
  year: 2017
  end-page: 9
  article-title: Off‐label use of drugs in regional anesthesia: a need for setting up policies
  publication-title: Journal of Anaesthesiology and Clinical Pharmacology
– year: 2018
  article-title: Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults
  publication-title: Cochrane Database of Systematic Reviews
– volume: 98
  start-page: 1050
  year: 2004
  end-page: 5
  article-title: Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery
  publication-title: Anesthesia and Analgesia
– volume: 15
  start-page: 664
  year: 1998
  end-page: 8
  article-title: Lignocaine plus morphine in bolus patient‐controlled intravenous analgesia lacks post‐operative morphine‐sparing effect
  publication-title: European Journal of Anaesthesiology
– volume: 115
  start-page: 1078
  year: 2012
  end-page: 84
  article-title: The effect of perioperative intravenous lidocaine and ketamine on recovery after abdominal hysterectomy
  publication-title: Anesthesia and Analgesia
– volume: 59
  start-page: 721
  year: 1987
  end-page: 4
  article-title: Effect of i.v. lignocaine on pain and the endocrine metabolic responses after surgery
  publication-title: British Journal of Anaesthesia
– volume: 18
  start-page: 373
  year: 2014
  end-page: 80
  article-title: Intravenous lidocaine for post‐operative pain relief after hand‐assisted laparoscopic colon surgery: a randomized, placebo‐controlled clinical trial
  publication-title: Techniques in Coloproctology
– volume: 105
  start-page: 151
  year: 2003
  end-page: 7
  article-title: What decline in pain intensity is meaningful to patients with acute pain?
  publication-title: Pain
– volume: 83
  start-page: 102
  year: 1996
  end-page: 6
  article-title: Equivalent outcomes during postoperative patient‐controlled intravenous analgesia with lidocaine plus morphine versus morphine alone
  publication-title: Anesthesia and Analgesia
– volume: 42
  start-page: 307
  year: 2014
  end-page: 19
  article-title: Efficacy of intraperitoneal and intravenous lidocaine on pain relief after laparoscopic cholecystectomy
  publication-title: Journal of International Medical Research
– volume: 6
  start-page: 245
  year: 1992
  end-page: 50
  article-title: Is intravenous lidocaine infusion suitable for postoperative pain management?
  publication-title: Schmerz
– year: 2014
– volume: 141
  start-page: 43
  year: 1981
  end-page: 5
  article-title: Continuous infusion of lidocaine in patients with cardiac arrhythmias
  publication-title: Archives of Internal Medicine
– volume: 72
  start-page: 12
  year: 2017
  end-page: 6
  article-title: Can systematic reviews with sparse data be trusted?
  publication-title: Anaesthesia
– volume: 74
  start-page: 292
  year: 2019
  end-page: 9
  article-title: A sustainable method to reduce postoperative oxycodone discharge prescribing in a metropolitan tertiary referral hospital
  publication-title: Anaesthesia
– volume: 179
  start-page: 383
  year: 1971
  end-page: 98
  article-title: Disposition kinetics of lidocaine in normal subjects
  publication-title: Annals of the New York Academy of Sciences
– volume: 17
  start-page: 1
  year: 1996
  end-page: 12
  article-title: Assessing the quality of reports of randomized clinical trials: is blinding necessary?
  publication-title: Controlled Clinical Trials
– volume: 29
  start-page: 537
  year: 2012
  end-page: 43
  article-title: No benefit from perioperative intravenous lidocaine in laparoscopic renal surgery: a randomised, placebo‐controlled study
  publication-title: European Journal of Anaesthesiology
– volume: 9
  start-page: 541
  year: 1995
  end-page: 6
  article-title: Lidocaine and the inhibition of postoperative pain in coronary artery bypass patients
  publication-title: Journal of Cardiothoracic and Vascular Anesthesia
– volume: 29
  start-page: 81
  year: 1957
  end-page: 3
  article-title: A personal account of lignocaine overdosage
  publication-title: British Journal of Anaesthesia
– volume: 110
  start-page: 4
  year: 2009
  end-page: 5
  article-title: In search of excellence in anaesthesiology
  publication-title: Anesthesiology
– year: 2019
  article-title: Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting
  publication-title: Cochrane Database of Systematic Reviews
– volume: 100
  start-page: 394
  year: 2015
  end-page: 401
  article-title: Intravenous lidocaine for effective pain relief after laparoscopic colectomy: a prospective, randomized, double‐blind, placebo‐controlled study
  publication-title: International Surgery
– volume: 65
  start-page: 92
  year: 2015
  end-page: 8
  article-title: Effect of intraoperative intravenous lidocaine on pain and plasma interleukin‐6 in patients undergoing hysterectomy
  publication-title: Revista Brasileira de Anestesiologia
– volume: 17
  start-page: 336
  year: 2017
  end-page: 43
  article-title: Effect of perioperative intravenous lidocaine infusion on acute and chronic pain after breast surgery: a meta‐analysis of randomized controlled trials
  publication-title: Pain Practice
– volume: 87
  start-page: 700
  year: 1977
  end-page: 6
  article-title: Pharmacokinetics of lidocaine after prolonged intravenous infusion in uncomplicated myocardial infarction
  publication-title: Annals of Internal Medicine
– volume: 9
  start-page: 87
  year: 2016
  end-page: 93
  article-title: The analgesic efficacy of intravenous lidocaine infusion after laparoscopic fundoplication: a prospective, randomised, double‐blind, placebo‐controlled trial
  publication-title: Local and Regional Anesthesia
– volume: 60
  start-page: 325
  year: 2010
  end-page: 33
  article-title: Intraoperative intravenous lidocaine
  publication-title: Revista Brasiliera de Anestesiologia
– volume: 4
  start-page: 17
  year: 2015
  end-page: 29
  article-title: Pharmacokinetics and pharmacodynamics of lignocaine: a review
  publication-title: World Journal of Anesthesiology
– volume: 39
  start-page: 2220
  year: 2015
  end-page: 34
  article-title: Efficacy of intravenous lidocaine for postoperative analgesia following laparoscopic surgery: a meta‐analysis
  publication-title: World Journal of Surgery
– volume: 7
  start-page: 205
  year: 2020
  end-page: 12
  article-title: Intravenous lidocaine for acute pain: a single‐institution retrospective study
  publication-title: Drugs – Real World Outcomes
– volume: 126
  start-page: 729
  year: 2017
  end-page: 37
  article-title: Perioperative use of intravenous lidocaine
  publication-title: Anesthesiology
– volume: 109
  start-page: 118
  year: 2008
  end-page: 23
  article-title: Lack of impact of intravenous lidocaine on analgesia, functional recovery, and nociceptive pain threshold after total hip arthroplasty
  publication-title: Anesthesiology
– year: 2016
– volume: 52
  start-page: 915
  year: 2005
  end-page: 20
  article-title: Communication between anesthesiologists, patients and the anesthesia team: a descriptive study of induction and emergence
  publication-title: Canadian Journal of Anaesthesia
– year: 2010
– volume: 15
  start-page: 136
  year: 2015
  end-page: 42
  article-title: Local anaesthetic systemic toxicity
  publication-title: British Journal of Anaesthesia Education
– volume: 54
  start-page: 549
  year: 2010
  end-page: 56
  article-title: Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy
  publication-title: Acta Anaesthesiologica Scandinavica
– year: 2009
  article-title: Premedication for anxiety in adult day surgery
  publication-title: Cochrane Database of Systematic Reviews
– volume: 35
  start-page: 370
  year: 2010
  end-page: 6
  article-title: Intravenous lidocaine is as effective as epidural bupivacaine in reducing ileus duration, hospital stay, and pain after open colon resection: a randomized clinical trial
  publication-title: Regional Anesthesia and Pain Medicine
– volume: 246
  start-page: 192
  year: 2007
  end-page: 200
  article-title: Systemic lidocaine shortens length of hospital stay after colorectal surgery: a double‐blinded, randomized, placebo‐controlled trial
  publication-title: Annals of Surgery
– volume: 323
  start-page: 42
  year: 2001
  end-page: 6
  article-title: Systematic reviews in health care: assessing the quality of controlled clinical trials
  publication-title: British Medical Journal
– volume: 8
  start-page: 1
  year: 2019
  article-title: Intravenous lidocaine infusion as a component of multimodal analgesia for colorectal surgery—measurement of plasma levels
  publication-title: Perioperative Medicine
– volume: 92
  start-page: 168
  year: 1976
  end-page: 73
  article-title: Clinical use and toxicity of intravenous lidocaine. A report from the Boston collaborative drug surveillance program
  publication-title: American Heart Journal
– volume: 123
  start-page: 335
  year: 2019
  end-page: 49
  article-title: Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review
  publication-title: British Journal of Anaesthesia
– volume: 172
  start-page: 1493
  year: 1960
  end-page: 8
  article-title: Comparison of toxicity of intravenously given local anaesthetic agents in man
  publication-title: Journal of the American Medical Association
– volume: 109
  start-page: 1464
  year: 2009
  end-page: 9
  article-title: The effect of perioperative intravenous lidocaine on postoperative pain and immune function
  publication-title: Anesthesia and Analgesia
– volume: 198
  start-page: 231
  year: 2009
  end-page: 6
  article-title: Can intravenous lidocaine decrease postsurgical ileus and shorten hospital stay in elective bowel surgery? A pilot study and literature review
  publication-title: American Journal of Surgery
– volume: 282
  start-page: 1054
  year: 1999
  end-page: 60
  article-title: The hazards of scoring the quality of clinical trials for meta‐analysis
  publication-title: Journal of the American Medical Association
– volume: 28
  start-page: 399
  year: 2011
  end-page: 400
  article-title: Measuring pain and analgesic response
  publication-title: European Journal of Anaesthesiology
– volume: 106
  start-page: 487
  year: 2011
  end-page: 93
  article-title: Impact of intravenous lidocaine on myocardial injury after off pump coronary artery surgery
  publication-title: British Journal of Anaesthesia
– volume: 21
  start-page: 841
  year: 2011
  end-page: 7
  article-title: An analysis of critical incidents relevant to paediatric anaesthesia reported to the UK National Reporting and Learning System, 2006–2008
  publication-title: Pediatric Anesthesia
– volume: 74
  start-page: 651
  year: 2019
  end-page: 62
  article-title: Analgesic impact of intra‐operative opioids vs. opioid‐free anaesthesia: a systematic review and meta‐analysis
  publication-title: Anaesthesia
– volume: 16
  start-page: 292
  year: 2016
  end-page: 8
  article-title: Intravenous lidocaine for acute pain: an evidence‐based clinical update
  publication-title: British Journal of Anaesthesia Education
– volume: 78
  start-page: 499
  year: 1973
  end-page: 508
  article-title: Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans
  publication-title: Annals of Internal Medicine
– year: 2019
  article-title: Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery
  publication-title: Cochrane Database of Systematic Reviews
– year: 2015
  article-title: Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery
  publication-title: Cochrane Database of Systematic Reviews
– volume: 70
  start-page: 1149
  year: 2010
  end-page: 63
  article-title: Impact of intravenous lidocaine infusion on postoperative analgesia and recovery from surgery: a systematic review of randomized controlled trials
  publication-title: Drugs
– volume: 57
  start-page: 175
  year: 2014
  end-page: 82
  article-title: Intraoperative systemic lidocaine for pre‐emptive analgesics in subtotal gastrectomy: a prospective, randomized, double‐blind, placebo‐controlled study
  publication-title: Canadian Journal of Surgery
– volume: 277
  start-page: 1215
  year: 1967
  end-page: 9
  article-title: Effect of lidocaine on ventricular arrhythmias in patients with coronary heart disease
  publication-title: New England Journal of Medicine
– volume: 23
  start-page: 663
  year: 2013
  end-page: 8
  article-title: Pre‐ and intraoperative lidocaine injection for preemptive analgesics in laparoscopic gastrectomy: a prospective, randomized, double‐blind, placebo‐controlled study
  publication-title: Journal of Laparoendoscopic and Advanced Surgical Techniques and Videoscopy
– year: 2019
  article-title: Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta‐analysis
  publication-title: Cochrane Database of Systematic Reviews
– volume: 100
  start-page: 448
  year: 2005
  end-page: 53
  article-title: The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy
  publication-title: Anesthesia and Analgesia
– volume: 28
  start-page: 427
  year: 2011
  end-page: 32
  article-title: Mean analgesic consumption is inappropriate for testing analgesic efficacy in post‐operative pain: analysis and alternative suggestion
  publication-title: European Journal of Anaesthesiology
– volume: 60
  start-page: 1453
  year: 2016
  end-page: 60
  article-title: Transversus abdominis plane block or intravenous lignocaine in open prostate surgery: a randomized controlled trial
  publication-title: Acta Anaesthesiologica Scandinavica
– volume: 2
  start-page: 98
  year: 2020
  end-page: 103
  article-title: A survey on the use of intravenous lidocaine infusion for acute pain in Scottish Hospitals
  publication-title: British Journal of Pain
– volume: 126
  start-page: 91
  year: 2006
  end-page: 101
  article-title: Gabapentin and postoperative pain: a systematic review of randomized controlled trials
  publication-title: Pain
– volume: 41
  start-page: 362
  year: 2016
  end-page: 7
  article-title: Systemic lidocaine fails to improve postoperative pain, but reduces time to discharge readiness in patients undergoing laparoscopic sterilization in day‐case surgery: a double‐blind, randomized, placebo‐controlled trial
  publication-title: Regional Anesthesia and Pain Medicine
– volume: 95
  start-page: 1331
  year: 2008
  end-page: 8
  article-title: Meta‐analysis of intravenous lidocaine and postoperative recovery after abdominal surgery
  publication-title: British Journal of Surgery
– volume: 14
  start-page: 231
  year: 1997
  end-page: 5
  article-title: ‘Off‐label’ use of prescription drugs: legal, clinical and policy considerations
  publication-title: European Journal of Anaesthesiology
– volume: 35
  start-page: 70
  year: 2016
  end-page: 7
  article-title: Effect of endovenous lidocaine on analgesia and serum cytokines: double‐blinded and randomized trial
  publication-title: Journal of Clinical Anesthesia
– volume: 2
  start-page: 31
  year: 1981
  end-page: 49
  article-title: A method for assessing the quality of a randomized control trial
  publication-title: Controlled Clinical Trials
– volume: 13
  start-page: 138
  year: 1958
  end-page: 46
  article-title: Intravenous lignocaine anaesthesia
  publication-title: Anaesthesia
– year: 2015
– volume: 40
  start-page: 296
  year: 1961
  end-page: 304
  article-title: Xylocaine for the relief of postoperative pain
  publication-title: Anesthesia and Analgesia
– volume: 86
  start-page: 235
  year: 1998
  end-page: 9
  article-title: Intravenous lidocaine speeds the return of bowel function, decreases postoperative pain, and shortens hospital stay in patients undergoing radical retropubic prostatectomy
  publication-title: Anesthesia and Analgesia
– volume: 4
  start-page: 4
  year: 1949
  end-page: 9
  article-title: Xylocaine, a new local analgesic
  publication-title: Anaesthesia
– volume: 116
  start-page: 1141
  year: 2013
  end-page: 61
  article-title: Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve blocks and intravenous drugs
  publication-title: Anesthesia and Analgesia
– volume: 25
  start-page: 3183
  year: 2011
  end-page: 90
  article-title: Intraperitoneal and intravenous lidocaine for effective pain relief after laparoscopic appendectomy: a prospective, randomized, double‐blind, placebo‐controlled study
  publication-title: Surgical Endoscopy
– volume: 71
  start-page: 405
  year: 2016
  end-page: 10
  article-title: A randomised controlled trial of peri‐operative lidocaine infusions for open radical prostatectomy
  publication-title: Anaesthesia
– volume: 75
  start-page: 15
  year: 2020
  end-page: 20
  article-title: Trial sequential analysis: adding a new dimension to meta‐analysis
  publication-title: Anaesthesia
– volume: 89
  start-page: 1345
  year: 1998
  end-page: 53
  article-title: Low‐dose lidocaine suppresses experimentally induced hyperalgesia in humans
  publication-title: Anesthesiology
– volume: 23
  start-page: 215
  year: 2009
  end-page: 21
  article-title: A randomised study of the effects of perioperative i.v. lidocaine on hemodynamic and hormonal responses for caesarean section
  publication-title: Journal of Anesthesia
– volume: 84
  start-page: 539
  year: 2014
  end-page: 44
  article-title: Early oral feeding following laparoscopic colorectal cancer surgery
  publication-title: Australia and New Zealand Journal of Surgery
– volume: 291
  start-page: 1324
  year: 1974
  end-page: 6
  article-title: Lidocaine in the prevention of primary ventricular fibrillation
  publication-title: New England Journal of Medicine
– year: 2009
  article-title: Ultrasound guidance for peripheral nerve blockade
  publication-title: Cochrane Database of Systematic Reviews
– volume: 106
  start-page: 11
  year: 2007
  end-page: 8
  article-title: Intravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy
  publication-title: Anesthesiology
– volume: 47
  start-page: 45
  year: 2009
  end-page: 7
  article-title: The licensing of medicines in the UK
  publication-title: Drug and Therapeutics Bulletin
– volume: 54
  start-page: 167
  year: 2016
  end-page: 93
  article-title: Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity
  publication-title: Clinical Toxicology
– volume: 28
  start-page: 567
  year: 2012
  end-page: 72
  article-title: Perioperative intravenous lidocaine decreases the incidence of persistent pain after breast surgery
  publication-title: Clinical Journal of Pain
– volume: 46
  start-page: 1082
  year: 1999
  end-page: 8
  article-title: Communication skills for anaesthetists: a practical introduction
  publication-title: Canadian Journal of Anaesthesia
– volume: 327
  start-page: 1379
  year: 2003
  article-title: Prophylactic respiratory physiotherapy after cardiac surgery: systematic review
  publication-title: British Medical Journal
– volume: 16
  start-page: 461
  year: 1961
  end-page: 78
  article-title: Concentrations of lignocaine in the blood after intravenous, intramuscular, epidural and endotracheal administration
  publication-title: Anaesthesia
– volume: 23
  start-page: 153
  year: 1951
  end-page: 61
  article-title: The toxicity of xylocaine
  publication-title: British Journal of Anaesthesia
– volume: 58
  start-page: 22
  year: 2011
  end-page: 37
  article-title: Perioperative intravenous lidocaine infusion for postoperative pain control: a meta‐analysis of randomized controlled trials
  publication-title: Canadian Journal of Anaesthesia
– volume: 64
  start-page: 971
  year: 1985
  end-page: 4
  article-title: Inhibition of postoperative pain by continuous low‐dose intravenous infusion of lidocaine
  publication-title: Anesthesia and Analgesia
– volume: 350
  start-page: h1481
  year: 2015
  article-title: Update on the UK law on consent
  publication-title: British Medical Journal
– volume: 55
  start-page: 754
  year: 2008
  end-page: 60
  article-title: Intraoperative infusion of lidocaine reduces postoperative fentanyl requirements in patients undergoing laparoscopic cholecystectomy
  publication-title: Canadian Journal of Anaesthesia
– volume: 55
  start-page: 1183
  year: 2012
  end-page: 94
  article-title: Perioperative systemic lidocaine for postoperative analgesia and recovery after abdominal surgery: a meta‐analysis of randomized controlled trials
  publication-title: Diseases of the Colon and Rectum
– volume: 103
  start-page: 213
  year: 2009
  end-page: 9
  article-title: Functional walking capacity as an outcome measure of laparoscopic prostatectomy: the effect of lidocaine infusion
  publication-title: British Journal of Anaesthesia
– ident: e_1_2_12_56_1
  doi: 10.1136/bmj.323.7303.42
– ident: e_1_2_12_106_1
  doi: 10.3109/15563650.2015.1121270
– ident: e_1_2_12_19_1
– ident: e_1_2_12_70_1
  doi: 10.1111/anae.13368
– ident: e_1_2_12_17_1
  doi: 10.1186/s13741-019-0112-4
– ident: e_1_2_12_20_1
  doi: 10.1097/ALN.0b013e318190b263
– ident: e_1_2_12_41_1
  doi: 10.1097/00000539-199607000-00018
– volume: 65
  start-page: 92
  year: 2015
  ident: e_1_2_12_68_1
  article-title: Effect of intraoperative intravenous lidocaine on pain and plasma interleukin‐6 in patients undergoing hysterectomy
  publication-title: Revista Brasileira de Anestesiologia
– ident: e_1_2_12_65_1
  doi: 10.9738/INTSURG-D-14-00225.1
– volume: 16
  start-page: 292
  year: 2016
  ident: e_1_2_12_10_1
  article-title: Intravenous lidocaine for acute pain: an evidence‐based clinical update
  publication-title: British Journal of Anaesthesia Education
– ident: e_1_2_12_84_1
  doi: 10.1007/s00540-009-0738-3
– ident: e_1_2_12_81_1
  doi: 10.1016/S1053-0770(05)80138-7
– ident: e_1_2_12_39_1
  doi: 10.1007/s12630-010-9332-2
– ident: e_1_2_12_34_1
  doi: 10.1213/01.ANE.0000104582.71710.EE
– ident: e_1_2_12_79_1
  doi: 10.7326/0003-4819-87-6-700
– ident: e_1_2_12_86_1
  doi: 10.1093/bja/aeq416
– ident: e_1_2_12_87_1
  doi: 10.1056/NEJM197412192912504
– ident: e_1_2_12_98_1
  doi: 10.1017/9781139626798
– ident: e_1_2_12_72_1
  doi: 10.1111/anae.13730
– ident: e_1_2_12_96_1
  doi: 10.1007/BF03022051
– ident: e_1_2_12_43_1
  doi: 10.1111/j.1399-6576.2009.02165.x
– ident: e_1_2_12_21_1
  doi: 10.1002/bjs.6375
– ident: e_1_2_12_102_1
– ident: e_1_2_12_73_1
  doi: 10.1111/anae.14705
– ident: e_1_2_12_91_1
  doi: 10.1016/S0002-8703(76)80252-9
– ident: e_1_2_12_66_1
  doi: 10.1097/AAP.0000000000000398
– year: 2019
  ident: e_1_2_12_63_1
  article-title: Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery
  publication-title: Cochrane Database of Systematic Reviews
– ident: e_1_2_12_54_1
  doi: 10.1002/14651858.CD003006.pub4
– ident: e_1_2_12_2_1
  doi: 10.1111/j.1365-2044.1949.tb05802.x
– ident: e_1_2_12_44_1
  doi: 10.1097/EJA.0b013e328356bad6
– ident: e_1_2_12_32_1
  doi: 10.1097/00000542-200701000-00007
– ident: e_1_2_12_85_1
  doi: 10.1097/AJP.0b013e31823b9cc8
– ident: e_1_2_12_45_1
  doi: 10.1007/s00464-011-1684-3
– ident: e_1_2_12_100_1
  doi: 10.1046/j.1365-2346.1997.00112.x
– ident: e_1_2_12_59_1
  doi: 10.1001/jama.282.11.1054
– ident: e_1_2_12_103_1
  doi: 10.1136/bmj.h1481
– ident: e_1_2_12_71_1
  doi: 10.1503/cjs.009613
– ident: e_1_2_12_25_1
  doi: 10.1111/papr.12442
– ident: e_1_2_12_9_1
  doi: 10.1016/j.bja.2019.06.014
– ident: e_1_2_12_49_1
  doi: 10.1177/0300060513505493
– ident: e_1_2_12_7_1
  doi: 10.1097/ALN.0000000000001527
– ident: e_1_2_12_55_1
  doi: 10.1002/14651858.CD006459.pub2
– ident: e_1_2_12_22_1
  doi: 10.2165/10898560-000000000-00000
– ident: e_1_2_12_60_1
  doi: 10.1097/EJA.0b013e328343c569
– ident: e_1_2_12_90_1
  doi: 10.5313/wja.v4.i2.17
– ident: e_1_2_12_8_1
  doi: 10.1177/2049463719873021
– ident: e_1_2_12_26_1
  doi: 10.1007/s00268-015-3105-6
– ident: e_1_2_12_30_1
  doi: 10.1093/bja/ael217
– volume: 60
  start-page: 325
  year: 2010
  ident: e_1_2_12_88_1
  article-title: Intraoperative intravenous lidocaine
  publication-title: Revista Brasiliera de Anestesiologia
  doi: 10.1016/S0034-7094(10)70041-6
– ident: e_1_2_12_35_1
  doi: 10.1016/j.amjsurg.2008.10.015
– ident: e_1_2_12_95_1
  doi: 10.1111/j.1460-9592.2010.03421.x
– ident: e_1_2_12_48_1
  doi: 10.1007/s10151-013-1065-0
– ident: e_1_2_12_74_1
  doi: 10.1001/jama.1960.03020140029007
– ident: e_1_2_12_57_1
  doi: 10.1136/bmj.327.7428.1379
– ident: e_1_2_12_12_1
  doi: 10.1111/anae.14582
– ident: e_1_2_12_93_1
  doi: 10.1007/s40801-020-00205-8
– ident: e_1_2_12_24_1
  doi: 10.1097/DCR.0b013e318259bcd8
– ident: e_1_2_12_107_1
– ident: e_1_2_12_92_1
  doi: 10.2147/LRA.S119483
– ident: e_1_2_12_14_1
  doi: 10.1093/bja/23.3.153
– ident: e_1_2_12_42_1
  doi: 10.1097/00003643-199811000-00007
– ident: e_1_2_12_62_1
  doi: 10.1002/14651858.CD012212.pub2
– ident: e_1_2_12_13_1
  doi: 10.1111/anae.14570
– ident: e_1_2_12_47_1
  doi: 10.1111/ans.12550
– ident: e_1_2_12_82_1
  doi: 10.1007/BF02527813
– ident: e_1_2_12_50_1
  doi: 10.1016/S0304-3959(03)00176-3
– ident: e_1_2_12_83_1
  doi: 10.1093/bja/59.6.721
– ident: e_1_2_12_11_1
  doi: 10.1213/ANE.0b013e318277a270
– ident: e_1_2_12_78_1
  doi: 10.1111/j.1749-6632.1971.tb46915.x
– volume-title: Acute Pain Management: Scientific Evidence
  year: 2015
  ident: e_1_2_12_105_1
– ident: e_1_2_12_75_1
  doi: 10.1111/j.1365-2044.1961.tb13426.x
– ident: e_1_2_12_33_1
  doi: 10.1213/01.ANE.0000142551.92340.CC
– ident: e_1_2_12_58_1
  doi: 10.1016/0197-2456(81)90056-8
– ident: e_1_2_12_77_1
  doi: 10.1001/archinte.1981.00340010039011
– ident: e_1_2_12_51_1
  doi: 10.1016/0197-2456(95)00134-4
– volume: 33
  start-page: 448
  year: 2017
  ident: e_1_2_12_101_1
  article-title: Off‐label use of drugs in regional anesthesia: a need for setting up policies
  publication-title: Journal of Anaesthesiology and Clinical Pharmacology
  doi: 10.4103/joacp.JOACP_341_15
– ident: e_1_2_12_76_1
  doi: 10.1056/NEJM196712072772301
– ident: e_1_2_12_89_1
  doi: 10.7326/0003-4819-78-4-499
– ident: e_1_2_12_27_1
  doi: 10.1002/14651858.CD009642.pub2
– ident: e_1_2_12_53_1
  doi: 10.1002/14651858.CD002192.pub2
– ident: e_1_2_12_46_1
  doi: 10.1089/lap.2012.0542
– ident: e_1_2_12_61_1
  doi: 10.1097/EJA.0b013e32834592a8
– ident: e_1_2_12_18_1
  doi: 10.1002/14651858.CD009642.pub3
– ident: e_1_2_12_97_1
  doi: 10.1007/BF03013207
– ident: e_1_2_12_38_1
  doi: 10.1007/BF03016348
– ident: e_1_2_12_67_1
  doi: 10.1111/aas.12773
– ident: e_1_2_12_37_1
  doi: 10.1093/bja/aep103
– ident: e_1_2_12_99_1
  doi: 10.1136/dtb.2009.03.0012
– ident: e_1_2_12_104_1
– ident: e_1_2_12_36_1
  doi: 10.1213/ANE.0b013e3181bab1bd
– volume: 15
  start-page: 136
  year: 2015
  ident: e_1_2_12_16_1
  article-title: Local anaesthetic systemic toxicity
  publication-title: British Journal of Anaesthesia Education
– ident: e_1_2_12_40_1
  doi: 10.1097/AAP.0b013e3181e8d5da
– ident: e_1_2_12_4_1
  doi: 10.1111/j.1365-2044.1958.tb08045.x
– ident: e_1_2_12_31_1
  doi: 10.1097/SLA.0b013e31805dac11
– ident: e_1_2_12_64_1
  doi: 10.1213/ANE.0b013e3182662e01
– ident: e_1_2_12_52_1
  doi: 10.1016/j.pain.2006.06.018
– ident: e_1_2_12_5_1
  doi: 10.1213/00000539-196105000-00011
– ident: e_1_2_12_80_1
  doi: 10.1097/ALN.0b013e31817b5a9b
– ident: e_1_2_12_94_1
  doi: 10.1111/anae.14519
– ident: e_1_2_12_23_1
  doi: 10.1007/s12630-010-9407-0
– ident: e_1_2_12_69_1
  doi: 10.1016/j.jclinane.2016.07.021
– ident: e_1_2_12_6_1
  doi: 10.1097/00000542-199812000-00011
– ident: e_1_2_12_3_1
– ident: e_1_2_12_29_1
  doi: 10.1097/00000539-199802000-00003
– ident: e_1_2_12_28_1
  doi: 10.1213/00000539-198510000-00005
– ident: e_1_2_12_15_1
  doi: 10.1093/bja/29.2.81
– reference: 33591570 - Anaesthesia. 2021 May;76(5):721
– reference: 33141932 - Anaesthesia. 2021 Feb;76(2):156-160
SSID ssj0012818
Score 2.6554673
Snippet Summary Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and...
Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and...
SourceID proquest
pubmed
crossref
wiley
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 238
SubjectTerms Administration, Intravenous
Anesthetics
Anesthetics, Local - administration & dosage
Anesthetics, Local - adverse effects
Anesthetics, Local - therapeutic use
Body weight
Chronic pain
Comorbidity
Consensus
efficacy
Humans
idocaine
Informed consent
Infusions, Intravenous
Intravenous administration
Lidocaine
Lidocaine - administration & dosage
Lidocaine - adverse effects
Lidocaine - therapeutic use
Local anesthesia
Nerve Block
Pain
Pain, Postoperative - prevention & control
Patient Safety
Patients
Postoperative period
Recovery
Recovery (Medical)
Recovery of Function
Risk Assessment
safety
Surgery
Treatment Outcome
Title The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fanae.15270
https://www.ncbi.nlm.nih.gov/pubmed/33141959
https://www.proquest.com/docview/2476330107
https://www.proquest.com/docview/2457668458
Volume 76
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEA6LXryI4qu-iOhFobBN02wrXhZ1EUERUfBW8oSFpbvYXWEv_nZn0se6KII9lNImDc3MJN-kk28IOVNaJJFlWejAtwh5BjaXAcwNuYtEqixojcINzg-P4u6V378lbx1y1eyFqfgh2gU3tAw_XqOBS1V-M3JZSIvZe3rgsK8Cqo9Rvxl_av8hIM9Rky8P5q2sJifFOJ5F3eXp6AfGXIasfs4ZbJD1GizSfiXdTdKxxRb5BMnSWWnp2NEhLs1-eJpVOhoamJfgsyjgUDpBwoyJrXi96QTuU1kYiv4vKO_8EqsulgKpxqDqooTX-B1GuGRIxwW1SDAh9dzXLaWz0_k2eRncvlzfhXUWhVDzJOuGEg7FuE4UFwLgnAEHLks04J5Umyh2USyZNYCCuspK12OGOxbFgqdaSsB68Q5ZKcaF3SNUGJdw6ZAuJ-WGCdkVhksBPolLlEmjgJw3fZnrmmEcE12M8sbTwH7Pfb8H5LQtO6l4NX4tddiIJK9tq8wZhzERxqVuLyAn7WOwCvzVIQsLXQ5lwI8SKU_SgOxWomybieOII6VOQC68bP9oP-8_9m_91f5_Ch-QNYahLz64-5CsTN9n9giwy1QdexWF880z-wLWF-sn
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8QwEA6iB734wFd9RvSiUNm2abb1toiyvvYgK3grecKidBe7K6wHf7szabc-EbSn0k4ammSSbyaTbwg5kIrHgQlT34Jt4bMUdC4FmOszG_BEGhg1Eg8433R4-45d3sf3VWwOnoUp-SFqhxtqhpuvUcHRIf1By0UuDKbvaYLFPuM26BAT3dbsUbhHlEwS5sHClVbspBjI817283r0DWR-xqxu0TlfKDOrFo6rEGNNHo5HQ3msXr4wOf77fxbJfAVHaascP0tkyuTL5BXGDh0VhvYt7aHz99kRudLHnoaVDyqigHTpACk5BqZkDqcDeE5Frila2KAe4xMs-u5spArDtvMCPuPOMKFTkvZzapDCQqixK1sIa4bjFdI9P-uetv0qT4OvWJw2fAGXDJmKJeMcAKMGEzGNFSCrROkgskEkQqMBZzWkEbYZambDIOIsUUIAmoxWyXTez806oVzbmAmLhDwJ0yEXDa6Z4GD12FjqJPDI4aSzMlVxmGMqjcdsYstgI2auET2yX8sOSuaOH6W2Jn2eVdpbZCGDWRdmvkbTI3v1a9A73EwRuYEmBxmw1HjC4sQja-VYqauJooAhaY9HjlyP_1J_1uq0ztzdxl-Ed8lsu3tznV1fdK42yVyIgTYulHyLTA-fRmYbkNJQ7jh9eAPL5w7G
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3da9swED9CCmUvY6Pt5i1bVdaXDgyxLCv26EtYG9JuC3noIG9G1gcUimOWtJCX_u27kz_SsFGon4x9srDuTvqddPoJ4LTQMoksz0KHsUUoMvS5DGFuKFwk08Ki1RS0wfnXTE5_i-tFsujBebsXpuaH6CbcyDN8f00OXhn3xMlVqSyd3jPCgH1PoOGRfXMx79YQiOeoPS8Px62sISelPJ5t2d3h6B-MuQtZ_ZgzeQOvG7DIxrV230LPlgfwiJpl9yvLlo7d0tTsg6dZZXe3Bscl_C2GOJRVRJhR2ZrXm1X4nKnSMIp_0Xg336jodiqQaUqqLlf4Gb_DiKYM2bJklggmlN74sivl7HpzCDeTy5vv07A5RSHUIsmGocKr4EInhZAS4ZzBAC5LNOKeVJsodlGsuDWIgoaFVW7EjXA8iqVItVKI9eIj6JfL0r4HJo1LhHJEl5MKw6UaSiOUxJjEJYVJowDO2rbMdcMwTgdd3OVtpEHtnvt2D-BLJ1vVvBr_lRq0Kskb31rlXGCfiP3ScBTASfcavYKWOlRpsclRBuMomYokDeBdrcqumjiOBFHqBPDV6_aZ-vPxbHzp7z68RPgY9ucXk_zn1ezHR3jFKQvG53kPoL_-c28_IYxZF5-9tf4FtcPs3w
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+use+of+intravenous+lidocaine+for+postoperative+pain+and+recovery%3A+international+consensus+statement+on+efficacy+and+safety&rft.jtitle=Anaesthesia&rft.au=Foo%2C+I&rft.au=Macfarlane%2C+A+J+R&rft.au=Srivastava%2C+D&rft.au=Bhaskar%2C+A&rft.date=2021-02-01&rft.eissn=1365-2044&rft.volume=76&rft.issue=2&rft.spage=238&rft_id=info:doi/10.1111%2Fanae.15270&rft_id=info%3Apmid%2F33141959&rft.externalDocID=33141959
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0003-2409&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0003-2409&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0003-2409&client=summon