The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect - Ries, Laure Nicolas Annick; Rocha, Marina Campos; de Castro, Patrícia Alves; Silva-Rocha, Rafael; Silva, Roberto Nascimento; Freitas, Fernanda Zanolli; de Assis, Leandro José; Bertolini, Maria Célia; Malavazi, Iran; Goldman, Gustavo H. (mBio, 2017)
Keywords: Aspergillosis - microbiology; Aspergillus fumigatus - drug effects; Aspergillus fumigatus - genetics; Caspofungin; Cell Wall - drug effects; Cell Wall - genetics; Cell Wall - metabolism; Chitin - metabolism; Chitin Synthase - genetics; Echinocandins - genetics; Echinocandins - metabolism; Echinocandins - pharmacology; Fungal Proteins - genetics; Fungal Proteins - metabolism; Gene Expression Regulation, Fungal - drug effects; Lipopeptides - genetics; Lipopeptides - metabolism; Lipopeptides - pharmacology; Mitogen-Activated Protein Kinase 1 - genetics; Mitogen-Activated Protein Kinase 1 - metabolism; Signal Transduction - drug effects; Transcription Factors - genetics; Transcription Factors - metabolism; paradoxical effect; cell wall integrity pathway; Aspergillus fumigatus; caspofungin