Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy - Lanaspa, Miguel A.; Ishimoto, Takuji; Cicerchi, Christina; Tamura, Yoshifuru; Roncal-Jimenez, Carlos A.; Chen, Wei; Tanabe, Katsuyuki; Andres-Hernando, Ana; Orlicky, David J.; Finol, Esteban; Inaba, Shinichiro; Li, Nanxing; et al. (Journal of the American Society of Nephrology, 2014)
Keywords: Animals; Basic Research; Blood Glucose - metabolism; Body Weight; Cell Line, Transformed; Chemokines - metabolism; Cytokines - metabolism; Diabetes Mellitus, Experimental - metabolism; Diabetes Mellitus, Experimental - pathology; Diabetic Nephropathies - metabolism; Diabetic Nephropathies - pathology; Fructokinases - metabolism; Fructose - biosynthesis; Fructose - metabolism; Humans; Kidney Cortex - enzymology; Kidney Cortex - pathology; Kidney Glomerulus - cytology; Kidney Glomerulus - pathology; Kidney Tubules, Proximal - enzymology; Kidney Tubules, Proximal - pathology; Macrophages - metabolism; Macrophages - pathology; Mice, Inbred C57BL; Mice, Knockout; Polymers - metabolism