Aberrant Function of the C-Terminal Tail of HIST1H1E Accelerates Cellular Senescence and Causes Premature Aging - Flex, Elisabetta; Martinelli, Simone; Van Dijck, Anke; Ciolfi, Andrea; Cecchetti, Serena; Coluzzi, Elisa; Pannone, Luca; Andreoli, Cristina; Radio, Francesca Clementina; Pizzi, Simone; Carpentieri, Giovanna; Bruselles, Alessandro; et al. (American journal of human genetics, 2019)
Keywords: accelerated aging; Aneuploidy; Cell Nucleolus - metabolism; cellular senescence; Cellular Senescence - physiology; Child; Chromatin - metabolism; chromatin compaction; chromatin dynamics; chromatin remodeling; DNA Methylation; Female; HIST1H1E; Histones - chemistry; Histones - physiology; Humans; Infant; linker histone; linker histone H1.4; Male; methylation profiling; Middle Aged; replicative senescence; accelerated aging; replicative senescence; cellular senescence; linker histone; chromatin remodeling; HIST1H1E; chromatin dynamics; linker histone H1.4; chromatin compaction; methylation profiling