Water-Soluble Antitumor Agents. I. Synthesis and Biological Activity of 6-S-Aminoacyloxymethyl Mercaptopurine Derivatives - KASHIDA, Tatsuo; TANAKA, Takashi; TSUJIHARA, Kenji; NARASAKI, Naoko; OHOHASHI, Motoaki; HASHIYAMA, Tomiki; ODA, Kouji; HARADA, Naoyuki; HONGU, MITSUYA (Chemical & pharmaceutical bulletin, 1995)
Keywords: 6-mercaptopurine derivative; Animals; Antineoplastic agents; Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; antitumor activity; Biological and medical sciences; Colonic Neoplasms - pathology; double grafted tumor system; Fibrosarcoma - pathology; General aspects; Magnetic Resonance Spectroscopy; Medical sciences; Mercaptopurine - analogs & derivatives; Mercaptopurine - chemical synthesis; Mercaptopurine - pharmacology; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pharmacology. Drug treatments; Sarcoma - pathology; Solubility; tumor immunity; Water - chemistry; water-soluble; Antineoplastic agent; Solid tumor; Purine derivatives; Rodentia; Malignant tumor; α-Aminoacid; Vertebrata; Immunostimulant agent; Experimental disease; Mammalia; Structure activity relation; Mouse; Animal; Water solubility; Chemical synthesis