Biases and Errors on Allele Frequency Estimation and Disease Association Tests of Next-Generation Sequencing of Pooled Samples - Chen, Xiaowei; Listman, Jennifer B.; Slack, Frank J.; Gelernter, Joel; Zhao, Hongyu (Genetic epidemiology, 2012)
Keywords: allele frequency estimation; Alleles; Bias; Bioinformatics; Computer Simulation; Data processing; Disease; disease association tests; Electronic Data Processing - methods; Gene Frequency; Gene polymorphism; Genetic Testing - methods; Humans; Models, Genetic; next-generation sequencing; Polymorphism, Single Nucleotide; pooled sequencing; Population genetics; Research Design; Sequence Analysis, DNA - methods; Single-nucleotide polymorphism; Software