Single‐cell RNA‐seq reveals altered NK cell subsets and reduced levels of cytotoxic molecules in patients with ankylosing spondylitis - Ren, Conglin; Li, Mingshuang; Zheng, Yang; Cai, Bingbing; Du, Weibin; Zhang, Helou; Wu, Fengqing; Tong, Mengsha; Lin, Fu; Wang, Jinfu; Quan, Renfu (Journal of cellular and molecular medicine, 2022)
Keywords: Ankylosing spondylitis; Arthritis; Autoimmune diseases; Bioinformatics; CD56 Antigen - genetics; Correlation analysis; Cytotoxicity; Disease; Endopeptidase; Flow Cytometry; Gene expression; Genomics; granzyme B; Humans; Killer Cells, Natural; Leukocytes (mononuclear); Leukocytes, Mononuclear - metabolism; Lymphocytes; Natural killer cells; Original; Peripheral blood mononuclear cells; Plasma; Plasma levels; Quality control; RNA-Seq; Serine proteinase; single‐cell RNA sequencing; Software; Spondylitis, Ankylosing - metabolism; Statistical analysis; Stem cells; Transcriptomics; peripheral blood mononuclear cells; single-cell RNA sequencing; granzyme B; natural killer cells; ankylosing spondylitis